Primary Site >> Stomach Cancer
Gene >> HIF1A
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. PMID: 12671019 |
Ref: [The overexpression and significance of MKP-1 in oxygen-deprived gastric cancer cell line SGC7901]. PMID: 15059515 Ref: Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation. PMID: 15199114 Ref: [Expressions and activities of Rho GTPases in hypoxia and its relationship with tumor angiogenesis]. PMID: 15555278 |
Ref: Inhibition of gastric cancer angiogenesis by vector-based RNA interference for Raf-1. PMID: 15662129 Ref: Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. PMID: 15864753 Ref: Is the hypoxia-inducible factor pathway important in gastric cancer? PMID: 16290133 |
Ref: Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer. PMID: 16338068 Ref: Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation. PMID: 16395716 Ref: Overexpression of hypoxia-inducible factor-1 alpha in gastric adenocarcinoma. PMID: 16557436 Ref: Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma. PMID: 16785763 Ref: Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas. PMID: 16847924 Ref: CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. PMID: 16865270 Ref: Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells. PMID: 16872154 Ref: Overexpression of hypoxia-inducible factor 1alpha and p53 is a marker for an unfavorable prognosis in gastric cancer. PMID: 16951228 Ref: Up-regulation of hypoxia-inducible factor-1 alpha and VEGF mRNAs in peritoneal dissemination of patients with gastric cancer. PMID: 17094412 Ref: [Expression and clinical significance of hypoxia-inducible factor-1alpha in gastric cancer]. PMID: 17094917 Ref: Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers. PMID: 17143338 Ref: Relationship of hypoxia-inducible factor 1alpha and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer. PMID: 17166265 |
Ref: Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model. PMID: 17230506 Ref: Hypoxia-inducible factor 1alpha regulates lung adenocarcinoma cell invasion. PMID: 17335808 Ref: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo. PMID: 17363505 Ref: Upregulation of hypoxia inducible factor 1alpha mRNA is associated with elevated vascular endothelial growth factor expression and excessive angiogenesis and predicts a poor prognosis in gastric carcinoma. PMID: 17461470 Ref: Involvement of MGr1-Ag/37LRP in the vincristine-induced HIF-1 expression in gastric cancer cells. PMID: 17476462 Ref: KCl depolarization increases HIF-1 transcriptional activity via the calcium-independent pathway in SGC7901 gastric cancer cells. PMID: 17519536 Ref: Structural basis for depletion of heat shock protein 90 client proteins by deguelin. PMID: 17565155 Ref: Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1. PMID: 17583950 Ref: [Expressions of hypoxia inducible factor-1alpha and insulin-like growth factor-II in gastric carcinoma: correlation with angiogenesis and prognosis]. PMID: 17953839 Ref: Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival. PMID: 18025805 Ref: Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis. PMID: 18089723 |
Ref: Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer. PMID: 17953712 Ref: A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer. PMID: 17984117 Ref: Down-regulation of cobalt-induced HIF-1alpha expression correlates with cell proliferation and apoptosis in human gastric carcinoma cells. PMID: 18202779 Ref: Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer. PMID: 18452596 Ref: Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis. PMID: 18521687 Ref: Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo. PMID: 18708754 Ref: Hypoxia-inducible factor 1alpha mediates anoikis resistance via suppression of alpha5 integrin. PMID: 19074877 Ref: mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo. PMID: 19189667 |
Ref: Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway. PMID: 18723843 Ref: RNAi-mediated inhibition of Raf-1 leads to decreased angiogenesis and tumor growth in gastric cancer. PMID: 19029826 Ref: Effects of HIF-1alpha on human gastric cancer cell apoptosis at different CO(2) pressures. PMID: 19048182 Ref: HIF-1alpha determines the metastatic potential of gastric cancer cells. PMID: 19223895 Ref: Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer. PMID: 19287200 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Association of the hypoxia inducible factor-1alpha gene polymorphisms with gastric cancer in Tibetans. PMID: 19504235 Ref: Radiosensitization effect of luteolin on human gastric cancer SGC-7901 cells. PMID: 19589287 Ref: Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation. PMID: 19602039 Ref: Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer. PMID: 19724845 Ref: mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. PMID: 19738050 Ref: [Relationship between the expression of hypoxia-inducible factor-1alpha and chemotherapy response in gastric carcinoma]. PMID: 19742344 Ref: Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers. PMID: 20078552 Ref: The clinicopathological significance of tissue levels of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in gastric cancer. PMID: 20431729 |
Ref: Anti-HIF-1alpha antibody-conjugated pluronic triblock copolymers encapsulated with Paclitaxel for tumor targeting therapy. PMID: 20004970 Ref: HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy. PMID: 20020496 Ref: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. PMID: 20043076 Ref: [Experimental study of HIF-1alpha antisense oligonucleotide on implanted human gastric cancer in nude mice]. PMID: 20369469 Ref: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines. PMID: 20428833 Ref: gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. PMID: 20452389 Ref: HIF-1alpha and HIF-2alpha correlate with migration and invasion in gastric cancer. PMID: 20559021 Ref: Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB. PMID: 20706634 Ref: [Effects of hypoxia-inducible factor-1alpha on human gastric cancer cell apoptosis under in vitro CO(2) pneumoperitoneum environment]. PMID: 21163055 Ref: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. PMID: 21194482 |
Ref: A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-kappaB promotes gastric tumour growth and angiogenesis. PMID: 21119667 Ref: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. PMID: 21286718 Ref: Establishment and characterization of chronic-hypoxia-resistant gastric cancer cell line MNK45/HYP. PMID: 21336723 Ref: Pigment epithelium-derived factor inhibits angiogenesis and growth of gastric carcinoma by down-regulation of VEGF. PMID: 21617872 Ref: Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules. PMID: 21696576 Ref: [The effect of RhoA and proteasome inhibitor MG132 on angiogenesis in tumors]. PMID: 21866623 Ref: The effects of recombinant human GH on promoting tumor growth depend on the expression of GH receptor in vivo. PMID: 21920991 Ref: Transcriptional up-regulation of RhoE by hypoxia-inducible factor (HIF)-1 promotes epithelial to mesenchymal transition of gastric cancer cells during hypoxia. PMID: 22037464 Ref: Eupatilin Inhibits Gastric Cancer Cell Growth by Blocking STAT3-Mediated VEGF Expression. PMID: 22076197 |
Ref: TFF3 mediated induction of VEGF via hypoxia in human gastric cancer SGC-7901 cells. PMID: 21769478 Ref: The increased expression of DEC1 gene is related to HIF-1alpha protein in gastric cancer cell lines. PMID: 21779800 Ref: Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF). PMID: 22593272 Ref: Anti-proliferation and anti-invasion effects of diosgenin on gastric cancer BGC-823 cells with HIF-1alpha shRNAs. PMID: 22754381 Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 Ref: Hypoxia induces CXCR4 expression and biological activity in gastric cancer cells through activation of hypoxia-inducible factor-1alpha. PMID: 23023480 Ref: Knockdown of hypoxia-inducible factor-1alpha accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines. PMID: 23181099 |
Ref: Clinicopathological significance of hypoxia-inducible factor-1 alpha (HIF-1alpha) expression in gastric cancer. PMID: 22350022 Ref: Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target. PMID: 23135628 Ref: Blockade of VEGFR-1 and VEGFR-2 enhances paclitaxel sensitivity in gastric cancer cells. PMID: 23364970 Ref: Differentiated embryonic chondrocyte-expressed gene 1 is associated with hypoxia-inducible factor 1alpha and Ki67 in human gastric cancer. PMID: 23445622 Ref: Expression of Rac1, HIF-1alpha, and VEGF in gastric carcinoma: correlation with angiogenesis and prognosis. PMID: 23485997 Ref: Molecular alterations in fibroblasts exposed to Helicobacter pylori: a missing link in bacterial inflammation progressing into gastric carcinogenesis? PMID: 23568974 Ref: Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma. PMID: 23569336 Ref: [18F]Fluorodeoxyglucose accumulation as a biological marker of hypoxic status but not glucose transport ability in gastric cancer. PMID: 23718763 Ref: Clinicopathological implications of the expression of hypoxia-related proteins in gastric cancer. PMID: 23935399 Ref: HIF-1alpha is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer. PMID: 23970191 Ref: Hypoxia-inducible factor 1 alpha (HIF-1alpha) as a prognostic indicator in patients with gastric tumors: a meta-analysis. PMID: 23991975 Ref: Prognostic value of HIF-1alpha expression in patients with gastric cancer. PMID: 24057269 Ref: The Critical Impact of HIF-1a on Gastric Cancer Biology. PMID: 24216696 Ref: RhoE promotes metastasis in gastric cancer through a mechanism dependent on enhanced expression of CXCR4. PMID: 24312338 Ref: [Expressions of Jumonji domain containing protein 2C and hypoxia-inducible factor-1alpha in gastric carcinoma and their clinical significance]. PMID: 24418035 Ref: [Effect of huazhuo jiedu hewei recipe on the mechanism of angiogenesis in precancerous lesions of gastric cancer rats]. PMID: 24483113 |
Ref: Prolyl hydroxylase 3 inhibited the tumorigenecity of gastric cancer cells. PMID: 23533015 Ref: RUNX3 inhibits hypoxia-inducible factor-1alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells. PMID: 23542169 Ref: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition. PMID: 24070739 Ref: Up-regulation of survivin by AKT and hypoxia-inducible factor 1alpha contributes to cisplatin resistance in gastric cancer. PMID: 24165223 Ref: Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer. PMID: 24287180 Ref: Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism. PMID: 24342832 Ref: Meta-analysis of immunohistochemical expression of hypoxia inducible factor-1alpha as a prognostic role in gastric cancer. PMID: 24574785 Ref: Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis. PMID: 24602839 Ref: HIF-1 alpha overexpression correlates with poor overall survival and disease-free survival in gastric cancer patients post-gastrectomy. PMID: 24614305 Ref: Clinical and prognostic significance of HIF-1alpha, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis. PMID: 24647137 Ref: Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cells. PMID: 24729089 Ref: Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia. PMID: 24764682 Ref: Inhibition of phosphoinositide 3-kinase/Akt pathway decreases hypoxia inducible factor-1alpha expression and increases therapeutic efficacy of paclitaxel in human hypoxic gastric cancer cells. PMID: 24765145 Ref: Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy. PMID: 24903273 Ref: MicroRNA-382 induced by HIF-1alpha is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog. PMID: 24914051 Ref: Altered expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory genes in gastric cancer tissues. PMID: 24927122 Ref: Validation of 2-mm tissue microarray technology in gastric cancer. Agreement of 2-mm TMAs and full sections for Glut-1 and Hif-1 alpha. PMID: 24982335 Ref: Kruppel-like factor 8 contributes to hypoxia-induced MDR in gastric cancer cells. PMID: 25040744 Ref: Peritoneal milky spots serve as a hypoxic niche and favor gastric cancer stem/progenitor cell peritoneal dissemination through hypoxia-inducible factor 1alpha. PMID: 25142304 Ref: Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells. PMID: 25320508 |
Ref: Comparison of site-specific gene expression levels in primary tumors and synchronous lymph node metastases in advanced gastric cancer. PMID: 24651981 Ref: The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. PMID: 25263443 Ref: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway. PMID: 25333894 Ref: Interplay between the prostaglandin transporter OATP2A1 and prostaglandin E2-mediated cellular effects. PMID: 25433165 Ref: MIR210 as a potential molecular target to block invasion and metastasis of gastric cancer. PMID: 25618442 Ref: Overexpression of CDX2 in gastric cancer cells promotes the development of multidrug resistance. PMID: 25628941 Ref: Antisense Long Noncoding RNA HIF1A-AS2 Is Upregulated in Gastric Cancer and Associated with Poor Prognosis. PMID: 25686741 Ref: Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. PMID: 25710915 Ref: CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer. PMID: 25843777 Ref: [Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway]. PMID: 25916117 Ref: Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance. PMID: 25956062 Ref: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling. PMID: 26101707 Ref: The potential predictive role of nuclear NHERF1 expression in advanced gastric cancer patients treated with epirubicin/oxaliplatin/capecitabine first line chemotherapy. PMID: 26126066 Ref: Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas. PMID: 26147886 Ref: HIF-1alpha Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a. PMID: 26292288 Ref: [Changes in the number of copies of genetic loci in gastric cancer]. PMID: 26299866 Ref: Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer. PMID: 26329876 Ref: Involvement of nuclear receptor RZR/RORgamma in melatonin-induced HIF-1alpha inactivation in SGC-7901 human gastric cancer cells. PMID: 26330273 Ref: The Apoptotic Effect of HIF-1alpha Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions. PMID: 26339797 Ref: Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments. PMID: 26385890 Ref: Increased levels of serum and tissue miR-107 in human gastric cancer: Correlation with tumor hypoxia. PMID: 26406411 Ref: Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. PMID: 26497999 Ref: Sulforaphane inhibits hypoxia-induced HIF-1alpha and VEGF expression and migration of human colon cancer cells. PMID: 26498863 Ref: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer. PMID: 26567773 Ref: microRNA-18a regulates gastric carcinoma cell apoptosis and invasion by suppressing hypoxia-inducible factor-1alpha expression. PMID: 26622381 |
Ref: Repression of PES1 expression inhibits growth of gastric cancer. PMID: 26423399 Ref: Rab11-FIP2 promotes the metastasis of gastric cancer cells. PMID: 26502090 Ref: PRL-3 promotes gastric cancer migration and invasion through a NF-kappaB-HIF-1alpha-miR-210 axis. PMID: 26548949 Ref: Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A. PMID: 26760764 Ref: Role of miR-27a, miR-181a and miR-20b in gastric cancer hypoxia-induced chemoresistance. PMID: 26793992 Ref: Impaired mitophagy activates mtROS/HIF-1alpha interplay and increases cancer aggressiveness in gastric cancer cells under hypoxia. PMID: 26820502 Ref: Cobalt chloride-mediated protein kinase Calpha (PKCalpha) phosphorylation induces hypoxia-inducible factor 1alpha (HIF1alpha) in the nucleus of gastric cancer cell. PMID: 26826385 Ref: Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer. PMID: 26893686 Ref: Enhancement of Drug Sensitivity by Knockdown of HIF-1alpha in Gastric Carcinoma Cells. PMID: 26931435 Ref: Inhibition of peritoneal metastasis of human gastric cancer cells by dextran sulphate through the reduction in HIF-1alpha and ITGbeta1 expression. PMID: 27004522 Ref: MicroRNA-421 regulated by HIF-1alpha promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer. PMID: 27016414 Ref: Tetracycline-inducible shRNA targeting antisense long non-coding RNA HIF1A-AS2 represses the malignant phenotypes of bladder cancer. PMID: 27018306 Ref: MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1alpha regulation. PMID: 27159677 Ref: [Expression of hypoxia-inducible factor 1alpha in gastric cancer and its clinical signficance]. PMID: 27266349 Ref: Hypoxic inactivation of glycogen synthase kinase-3beta promotes gastric tumor growth and angiogenesis by facilitating hypoxia-inducible factor-1 signaling. PMID: 27365055 Ref: Melatonin downregulates nuclear receptor RZR/RORgamma expression causing growth-inhibitory and anti-angiogenesis activity in human gastric cancer cells in vitro and in vivo. PMID: 27446366 Ref: Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway. PMID: 27590684 |
Ref: Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer. PMID: 27902480 Ref: Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation. PMID: 28061458 Ref: Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer. PMID: 28069585 Ref: HIF-1alpha induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway. PMID: 28076840 Ref: The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer. PMID: 28122299 Ref: Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer. PMID: 28173803 Ref: Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia. PMID: 28281307 Ref: Hypoxia regulates CD44 expression via hypoxia-inducible factor-1alpha in human gastric cancer cells. PMID: 28356986 Ref: Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1alpha to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells. PMID: 28401064 Ref: MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1alpha regulation. PMID: 28414319 Ref: Chemotherapy regimen based on sorafenib combined with 5-FU on HIF-1alpha and VEGF expression and survival in advanced gastric cancer patients. PMID: 28454454 Ref: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors. PMID: 28594907 Ref: Hypoxia/IL-1alpha axis promotes gastric cancer progression and drug resistance. PMID: 28608600 Ref: Hypoxia-inducible factor-1alpha plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PMID: 28617871 Ref: Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma. PMID: 28848967 Ref: Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. PMID: 28894280 Ref: PHD3 affects gastric cancer progression by negatively regulating HIF1A. PMID: 28901473 Ref: Tumor microenvironment interruption: a novel anti-cancer mechanism of Proton-pump inhibitor in gastric cancer by suppressing the release of microRNA-carrying exosomes. PMID: 28979813 Ref: Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1alpha and GRP78. PMID: 29072683 Ref: Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer by Helicobacter pylori oncoprotein CagA. PMID: 29108235 |
Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 28915664 Ref: Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin beta4/FAK/SOX2/HIF-1alpha signaling pathway in gastric cancer. PMID: 29059156 Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 29328491 Ref: Long noncoding RNA BC005927 upregulates EPHB4 and promotes gastric cancer metastasis under hypoxia. PMID: 29383777 Ref: A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer. PMID: 29563065 Ref: Astragaloside IV reverses MNNG-induced precancerous lesions of gastric carcinoma in rats: Regulation on glycolysis through miRNA-34a/LDHA pathway. PMID: 29577459 Ref: Acetylation-mediated Siah2 stabilization enhances PHD3 degradation in Helicobacter pylori-infected gastric epithelial cancer cells. PMID: 29688807 Ref: Pachymic Acid Sensitizes Gastric Cancer Cells to Radiation Therapy by Upregulating Bax through Hypoxia. PMID: 29737213 Ref: Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer. PMID: 29785022 Ref: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. PMID: 29858600 Ref: Downregulation of HIF-1alpha inhibits the proliferation, migration and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression. PMID: 29899167 Ref: Prognostic value of hypoxia-inducible factor-1 alpha and prolyl 4-hydroxylase beta polypeptide overexpression in gastric cancer. PMID: 29904245 Ref: Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer. PMID: 29992789 Ref: The effect of HIF-1alpha and PKM1 expression on acquisition of chemoresistance. PMID: 30013393 Ref: The molecular mechanism and clinical significance of LDHA in HER2-mediated progression of gastric cancer. PMID: 30093943 Ref: Weipixiao attenuate early angiogenesis in rats with gastric precancerous lesions. PMID: 30200948 Ref: Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells. PMID: 30226558 Ref: Dextran sulfate inhibition on human gastric cancer cells invasion, migration and epithelial-mesenchymal transformation. PMID: 30250571 Ref: Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1alpha signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo. PMID: 30349304 |