Literatures

Primary Site >> Colorectal Cancer

Gene >> HIF1A

1.
Journal:	J Cancer Res Clin Oncol. 1998;124(6):315-20.
Title:	Expression of hypoxia-inducible genes in tumor cells.
Author:	Kress, S\|Stein, A\|Maurer, P\|Weber, B\|Reichert, J\|Buchmann, A\|Huppert, P\|Schwarz, M
PMID:	9692838

2.
Journal:	Mol Carcinog. 2002 Apr;33(4):198-205.
Title:	Quinoxaline 1,4-dioxides: hypoxia-selective therapeutic agents.
Author:	Diab-Assef, Mona\|Haddadin, Makhluf J\|Yared, Pierre\|Assaad, Chafika\|Gali-Muhtasib, Hala U
PMID:	11933073

3.
Journal:	Carcinogenesis. 2002 May;23(5):735-40.
Title:	Modulation of angiogenesis-related proteins synthesis by sodium butyrate in colon cancer cell line HT29.
Author:	Pellizzaro, Cinzia\|Coradini, Danila\|Daidone, Maria Grazia
PMID:	12016145

4.
Journal:	J Biol Chem. 2002 Oct 11;277(41):38205-11.
Title:	Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.
Author:	Fukuda, Ryo\|Hirota, Kiichi\|Fan, Fan\|Jung, Young Do\|Ellis, Lee M\|Semenza, Gregg L
PMID:	12149254

5.
Journal:	Cancer Res. 2002 Sep 1;62(17):5089-95.
Title:	The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
Author:	Welsh, Sarah J\|Bellamy, William T\|Briehl, Margaret M\|Powis, Garth
PMID:	12208766

6.
Journal:	Pathobiology. 2002-2003;70(6):348-52.
Title:	A role of histone H4 hypoacetylation in vascular endothelial growth factor expression in colon mucosa adjacent to implanted cancer in athymic mice cecum.
Author:	Kuniyasu, Hiroki\|Chihara, Yoshitomo\|Kondo, Hideaki
PMID:	12865631

7.
Journal:	Biochem Biophys Res Commun. 2003 Jan 24;300(4):832-8.
Title:	Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1alpha nuclear translocation.
Author:	Zgouras, Dimitrios\|Wachtershauser, Astrid\|Frings, Daniela\|Stein, Jurgen
PMID:	12559948

8.
Journal:	Cancer Res. 2003 Mar 1;63(5):1138-43.
Title:	Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.
Author:	Krishnamachary, Balaji\|Berg-Dixon, Shannon\|Kelly, Brian\|Agani, Faton\|Feldser, David\|Ferreira, Gloria\|Iyer, Narayan\|LaRusch, Jessica\|Pak, Brian\|Taghavi, Panthea\|Semenza, Gregg L
PMID:	12615733

9.
Journal:	Mol Cancer Ther. 2003 Mar;2(3):235-43.
Title:	The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation.
Author:	Welsh, Sarah J\|Williams, Ryan R\|Birmingham, Anne\|Newman, David J\|Kirkpatrick, D Lynn\|Powis, Garth
PMID:	12657718

10.
Journal:	Int J Cancer. 2003 Jun 10;105(2):176-81.
Title:	Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.
Author:	Kuwai, Toshio\|Kitadai, Yasuhiko\|Tanaka, Shinji\|Onogawa, Seiji\|Matsutani, Norimasa\|Kaio, Eijiro\|Ito, Masanori\|Chayama, Kazuaki
PMID:	12673675

11.
Journal:	Cancer Res. 2003 May 1;63(9):2330-4.
Title:	Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.
Author:	Fukuda, Ryo\|Kelly, Brian\|Semenza, Gregg L
PMID:	12727858

12.
Journal:	Med Hypotheses. 2003 Nov-Dec;61(5-6):567-73.
Title:	Hyperinsulinemia may boost both hematocrit and iron absorption by up-regulating activity of hypoxia-inducible factor-1alpha.
Author:	McCarty, M F
PMID:	14592787

13.
Journal:	Ai Zheng. 2003 Nov;22(11):1170-4.
Title:	[Relationship of hypoxia-inducible factor 1 alpha (HIF-1alpha) gene expression with vascular endothelial growth factor (VEGF) and microvessel density (MVD) in human colorectal adenoma and adenocarcinoma].
Author:	Jiang, Cong-Qing\|Liu, Zhi-Su\|Qian, Qun\|He, Yue-Ming\|Yuan, Yu-Feng\|Ai, Zhong-Li
PMID:	14613646

14.
Journal:	Cancer Res. 2003 Dec 15;63(24):8777-83.
Title:	Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
Author:	Erez, Neta\|Milyavsky, Michael\|Eilam, Raya\|Shats, Igor\|Goldfinger, Naomi\|Rotter, Varda
PMID:	14695194

15.
Journal:	Cancer Sci. 2004 Feb;95(2):149-53.
Title:	Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha.
Author:	Kuwai, Toshio\|Kitadai, Yasuhiko\|Tanaka, Shinji\|Hiyama, Toru\|Tanimoto, Keiji\|Chayama, Kazuaki
PMID:	14965365

16.
Journal:	Cancer Res. 2004 Mar 1;64(5):1765-72.
Title:	Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.
Author:	Mizukami, Yusuke\|Li, Jingnan\|Zhang, Xiaobo\|Zimmer, Michael A\|Iliopoulos, Othon\|Chung, Daniel C
PMID:	14996738

17.
Journal:	Mol Cell Biol. 2004 Apr;24(7):2875-89.
Title:	Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.
Author:	Erler, Janine T\|Cawthorne, Christopher J\|Williams, Kaye J\|Koritzinsky, Marianne\|Wouters, Bradley G\|Wilson, Clare\|Miller, Crispin\|Demonacos, Costas\|Stratford, Ian J\|Dive, Caroline
PMID:	15024076

18.
Journal:	Mol Cancer Ther. 2004 Mar;3(3):233-44.
Title:	Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.
Author:	Welsh, Sarah\|Williams, Ryan\|Kirkpatrick, Lynn\|Paine-Murrieta, Gillian\|Powis, Garth
PMID:	15026543

19.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2004 Jun;33(3):242-6.
Title:	[Expression and pathobiological implication of hypoxia-inducible factor-1alpha in human colorectal carcinoma].
Author:	Fan, Li-Fang\|Diao, Lu-Ming\|Jiang, Cong-Qing\|Tang, Zhi-Jiao\|Xia, Dong\|Liu, Ming-Qiu\|Liu, Zhi-Su\|Ai, Zhong-Li
PMID:	15256117

20.
Journal:	Carcinogenesis. 2004 Dec;25(12):2303-10. Epub 2004 Sep 9.
Title:	n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway.
Author:	Calviello, Gabriella\|Di Nicuolo, Fiorella\|Gragnoli, Simona\|Piccioni, Elisabetta\|Serini, Simona\|Maggiano, Nicola\|Tringali, Giuseppe\|Navarra, Pierluigi\|Ranelletti, Franco O\|Palozza, Paola
PMID:	15358633

21.
Journal:	Oncol Rep. 2004 Nov;12(5):1033-7.
Title:	Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma.
Author:	Kuwai, Toshio\|Kitadai, Yasuhiko\|Tanaka, Shinji\|Kuroda, Tsuyoshi\|Ochiumi, Takehiko\|Matsumura, Shunji\|Oue, Naohide\|Yasui, Wataru\|Kaneyasu, Mika\|Tanimoto, Keiji\|Nishiyama, Masahiko\|Chayama, Kazuaki
PMID:	15492789

22.
Journal:	Chin Med J (Engl). 2004 Oct;117(10):1541-6.
Title:	Expression levels and significance of hypoxia inducible factor-1 alpha and vascular endothelial growth factor in human colorectal adenocarcinoma.
Author:	Jiang, Cong-qing\|Fan, Li-fang\|Liu, Zhi-su\|Qian, Qun\|Xia, Dong\|Diao, Lu-ming\|He, Yue-ming\|Ai, Zhong-li
PMID:	15498380

23.
Journal:	Clin Cancer Res. 2004 Dec 15;10(24):8554-60.
Title:	Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression.
Author:	Yoshimura, Hiroshi\|Dhar, Dipok Kumar\|Kohno, Hitoshi\|Kubota, Hirofumi\|Fujii, Toshiyuki\|Ueda, Shuhei\|Kinugasa, Shoichi\|Tachibana, Mitsuo\|Nagasue, Naofumi
PMID:	15623639

24.
Journal:
Title:	(125)I-Labeled mouse anti-human carbonic anhydrase IX monoclonal antibody
Author:	Shan, Liang
PMID:	22675743

25.
Journal:	Cancer Res. 2005 Jul 15;65(14):6151-8.
Title:	A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia.
Author:	Nelson, Daniel W\|Cao, Hongbin\|Zhu, Yonghua\|Sunar-Reeder, Bulbin\|Choi, Clara Y H\|Faix, James D\|Brown, J Martin\|Koong, Albert C\|Giaccia, Amato J\|Le, Quynh-Thu
PMID:	16024616

26.
Journal:	Clin Cancer Res. 2005 Aug 1;11(15):5526-33.
Title:	A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.
Author:	Mackay, Helen\|Hedley, David\|Major, Pierre\|Townsley, Carol\|Mackenzie, Mary\|Vincent, Mark\|Degendorfer, Pam\|Tsao, Ming-Sound\|Nicklee, Trudey\|Birle, Diana\|Wright, John\|Siu, Lillian\|Moore, Malcolm\|Oza, Amit
PMID:	16061869

27.
Journal:	Cancer Res. 2005 Aug 15;65(16):7259-66.
Title:	Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors.
Author:	Sobhanifar, Solmaz\|Aquino-Parsons, Christina\|Stanbridge, Eric J\|Olive, Peggy
PMID:	16103077

28.
Journal:	Endocrinology. 2005 Nov;146(11):4951-60. Epub 2005 Aug 18.
Title:	Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.
Author:	Yeung, Ho Y\|Lai, Keng P\|Chan, Hoi Y\|Mak, Nai K\|Wagner, Graham F\|Wong, Chris K C
PMID:	16109785

29.
Journal:	Nat Med. 2005 Sep;11(9):992-7. Epub 2005 Aug 28.
Title:	Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.
Author:	Mizukami, Yusuke\|Jo, Won-Seok\|Duerr, Eva-Maria\|Gala, Manish\|Li, Jingnan\|Zhang, Xiaobo\|Zimmer, Michael A\|Iliopoulos, Othon\|Zukerberg, Lawrence R\|Kohgo, Yutaka\|Lynch, Maureen P\|Rueda, Bo R\|Chung, Daniel C
PMID:	16127434

30.
Journal:	Clin Exp Metastasis. 2005;22(1):25-30.
Title:	Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer.
Author:	Koukourakis, Michael I\|Giatromanolaki, Alexandra\|Simopoulos, Costantinos\|Polychronidis, Alexandros\|Sivridis, Efthimios
PMID:	16132575

31.
Journal:	J Clin Pathol. 2005 Oct;58(10):1033-8.
Title:	Proliferating fibroblasts at the invading tumour edge of colorectal adenocarcinomas are associated with endogenous markers of hypoxia, acidity, and oxidative stress.
Author:	Sivridis, E\|Giatromanolaki, A\|Koukourakis, M I
PMID:	16189147

32.
Journal:	Cancer Biol Ther. 2005 Oct;4(10):1068-74. Epub 2005 Oct 18.
Title:	Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment.
Author:	Mayes, Patrick A\|Campbell, Latoya\|Ricci, M Stacey\|Plastaras, John P\|Dicker, David T\|El-Deiry, Wafik S
PMID:	16294025

33.
Journal:	Int J Colorectal Dis. 2006 Apr;21(3):248-57.
Title:	Hypoxia, angiogenesis and apoptosis markers in locally advanced rectal cancer.
Author:	Theodoropoulos, George E\|Lazaris, Andreas C\|Theodoropoulos, Vasilios E\|Papatheodosiou, Kalliopi\|Gazouli, Maria\|Bramis, John\|Patsouris, Efstratios\|Panoussopoulos, Dimitrios
PMID:	16052307

34.
Journal:	Oncogene. 2006 May 18;25(21):3065-70.
Title:	Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.
Author:	Giles, R H\|Lolkema, M P\|Snijckers, C M\|Belderbos, M\|van der Groep, P\|Mans, D A\|van Beest, M\|van Noort, M\|Goldschmeding, R\|van Diest, P J\|Clevers, H\|Voest, E E
PMID:	16407833

35.
Journal:	Cancer Res. 2006 Feb 1;66(3):1684-936.
Title:	Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts.
Author:	Dang, Duyen T\|Chen, Fang\|Gardner, Lawrence B\|Cummins, Jordan M\|Rago, Carlo\|Bunz, Fred\|Kantsevoy, Sergey V\|Dang, Long H
PMID:	16452228

36.
Journal:	Biochem Biophys Res Commun. 2006 Apr 28;343(1):8-14.
Title:	Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.
Author:	Woo, Kyung Jin\|Lee, Tae-Jin\|Park, Jong-Wook\|Kwon, Taeg Kyu
PMID:	16527254

37.
Journal:	J Biol Chem. 2006 May 19;281(20):13957-63. Epub 2006 Mar 16.
Title:	Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc.
Author:	Mizukami, Yusuke\|Fujiki, Kotoyo\|Duerr, Eva-Maria\|Gala, Manish\|Jo, Won-Seok\|Zhang, Xiaobo\|Chung, Daniel C
PMID:	16543245

38.
Journal:	Chin Med J (Engl). 2006 May 5;119(9):713-8.
Title:	Hypoxia-inducible factor-1alpha induces the epithelial-mesenchymal transition of human prostatecancer cells.
Author:	Luo, Yong\|He, Da-lin\|Ning, Liang\|Shen, Shu-lin\|Li, Lei\|Li, Xiang
PMID:	16701010

39.
Journal:	Carcinogenesis. 2006 Dec;27(12):2455-63.
Title:	An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.
Author:	Lee, Hyo-Jeong\|Lee, Eun-Ok\|Rhee, Yun-Hee\|Ahn, Kyoo Seok\|Li, Guang-Xun\|Jiang, Cheng\|Lu, Junxuan\|Kim, Sung-Hoon
PMID:	16777983

40.
Journal:	Cancer Res. 2006 Jul 1;66(13):6683-91.
Title:	Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia.
Author:	Kaidi, Abderrahmane\|Qualtrough, David\|Williams, Ann C\|Paraskeva, Christos
PMID:	16818642

41.
Journal:	Nat Med. 2006 Jul;12(7):809-16.
Title:	E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis.
Author:	Jung, Cho-Rok\|Hwang, Kyung-Sun\|Yoo, Jinsang\|Cho, Won-Kyung\|Kim, Jin-Man\|Kim, Woo Ho\|Im, Dong-Soo
PMID:	16819549

42.
Journal:	Cancer Sci. 2006 Jul;97(7):582-8.
Title:	Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer.
Author:	Koukourakis, Michael I\|Giatromanolaki, Alexandra\|Polychronidis, Alexandros\|Simopoulos, Costantinos\|Gatter, Kevin C\|Harris, Adrian L\|Sivridis, Efthimios
PMID:	16827797

43.
Journal:	Korean J Gastroenterol. 2006 Jul;48(1):9-18.
Title:	[Modulation of colon cancer cell invasiveness induced by deoxycholic acid].
Author:	Kim, Hyun Soo\|Lee, Yong Kyu\|Kim, Jae Woo\|Baik, Soon Koo\|Kwon, Sang Ok\|Jang, Hwa In
PMID:	16861876

44.
Journal:	Mol Carcinog. 2006 Nov;45(11):833-40.
Title:	Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients.
Author:	Fransen, Karin\|Fenech, Matthew\|Fredrikson, Mats\|Dabrosin, Charlotta\|Soderkvist, Peter
PMID:	16865676

45.
Journal:	J Clin Oncol. 2006 Sep 10;24(26):4301-8. Epub 2006 Aug 8.
Title:	Lactate dehydrogenase 5 expression in operable colorectal cancer: strong association with survival and activated vascular endothelial growth factor pathway--a report of the Tumour Angiogenesis Research Group.
Author:	Koukourakis, Michael I\|Giatromanolaki, Alexandra\|Sivridis, Efthimios\|Gatter, Kevin C\|Harris, Adrian L
PMID:	16896001

46.
Journal:	World J Gastroenterol. 2006 Aug 7;12(29):4660-4.
Title:	Expression of NOS and HIF-1alpha in human colorectal carcinoma and implication in tumor angiogenesis.
Author:	Yu, Jian-Xian\|Cui, Lin\|Zhang, Qi-Yi\|Chen, Hua\|Ji, Ping\|Wei, Hong-Jun\|Ma, Hai-Yan
PMID:	16937436

47.
Journal:	Oncogene. 2007 Jan 11;26(2):312-20.
Title:	Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis.
Author:	Laiho, P\|Kokko, A\|Vanharanta, S\|Salovaara, R\|Sammalkorpi, H\|Jarvinen, H\|Mecklin, J-P\|Karttunen, T J\|Tuppurainen, K\|Davalos, V\|Schwartz, S Jr\|Arango, D\|Makinen, M J\|Aaltonen, L A
PMID:	16819509

48.
Journal:	Med Hypotheses. 2007;68(1):162-5.
Title:	Heparanase promotes angiogenesis through Cox-2 and HIF1alpha.
Author:	Naomoto, Yoshio\|Gunduz, Mehmet\|Takaoka, Munenori\|Okawa, Takaomi\|Gunduz, Esra\|Nobuhisa, Tetsuji\|Kobayashi, Masahiko\|Shirakawa, Yasuhiro\|Yamatsuji, Tomoki\|Sonoda, Ryutaro\|Matsuoka, Junji\|Tanaka, Noriaki
PMID:	16890383

49.
Journal:	Int J Sports Med. 2007 May;28(5):361-7.
Title:	Exercise associated genes in rat colon mucosa: upregulation of ornithin decarboxylase-1.
Author:	Buehlmeyer, K\|Doering, F\|Daniel, H\|Schulz, T\|Michna, H
PMID:	17111318

50.
Journal:	Histopathology. 2007 Jan;50(1):131-50.
Title:	Colorectal serrated adenocarcinoma.
Author:	Makinen, M J
PMID:	17204027

51.
Journal:	Br J Cancer. 2007 Mar 12;96(5):692-700. Epub 2007 Feb 13.
Title:	Recombinant human erythropoietin alpha modulates the effects of radiotherapy on colorectal cancer microvessels.
Author:	Ceelen, W\|Boterberg, T\|Smeets, P\|Van Damme, N\|Demetter, P\|Zwaenepoel, O\|Cesteleyn, L\|Houtmeyers, P\|Peeters, M\|Pattyn, P
PMID:	17299396

52.
Journal:	Cancer Res. 2007 Feb 15;67(4):1735-43.
Title:	Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.
Author:	Birle, Diana C\|Hedley, David W
PMID:	17308115

53.
Journal:	Pathol Oncol Res. 2007;13(1):15-20.
Title:	Clinicopathological significance and linkage of the distribution of HIF-1alpha and GLUT-1 in human primary colorectal cancer.
Author:	Wincewicz, Andrzej\|Sulkowska, Mariola\|Koda, Mariusz\|Sulkowski, Stanislaw
PMID:	17387384

54.
Journal:	Cancer Res. 2007 Apr 1;67(7):3263-8.
Title:	Isoleucine, an essential amino acid, prevents liver metastases of colon cancer by antiangiogenesis.
Author:	Murata, Kazumoto\|Moriyama, Masami
PMID:	17409434

55.
Journal:	Mol Cancer Ther. 2007 Apr;6(4):1433-9.
Title:	1alpha,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells.
Author:	Ben-Shoshan, Moshe\|Amir, Sharon\|Dang, Duyen T\|Dang, Long H\|Weisman, Yosef\|Mabjeesh, Nicola J
PMID:	17431122

56.
Journal:	Cell Oncol. 2007;29(3):229-40.
Title:	Stromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas.
Author:	Cleven, Arjen H G\|van Engeland, Manon\|Wouters, Bradly G\|de Bruine, Adriaan P
PMID:	17452775

57.
Journal:	Mol Pharmacol. 2007 Aug;72(2):395-406.
Title:	Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
Author:	Merighi, Stefania\|Benini, Annalisa\|Mirandola, Prisco\|Gessi, Stefania\|Varani, Katia\|Simioni, Carolina\|Leung, Edward\|Maclennan, Stephen\|Baraldi, Pier Giovanni\|Borea, Pier Andrea
PMID:	17488804

58.
Journal:	Pathology. 2007 Jun;39(3):334-8.
Title:	Cumulative expression of HIF-1-alpha, Bax, Bcl-xL and P53 in human colorectal cancer.
Author:	Wincewicz, Andrzei\|Sulkowska, Mariola\|Koda, Mariusz\|Sulkowski, Stanislaw
PMID:	17558861

59.
Journal:	World J Gastroenterol. 2007 May 28;13(20):2803-10.
Title:	Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.
Author:	Koshiji, Minori\|Kumamoto, Kensuke\|Morimura, Keiichirou\|Utsumi, Yasufumi\|Aizawa, Michiko\|Hoshino, Masami\|Ohki, Shinji\|Takenoshita, Seiichi\|Costa, Max\|Commes, Therese\|Piquemal, David\|Harris, Curtis-C\|Tchou-Wong, Kam-Meng
PMID:	17569115

60.
Journal:	Ann Oncol. 2007 Jun;18 Suppl 6:vi116-9.
Title:	Expression of the obesity hormone leptin and its receptor correlates with hypoxia-inducible factor-1 alpha in human colorectal cancer.
Author:	Koda, M\|Sulkowska, M\|Kanczuga-Koda, L\|Cascio, S\|Colucci, G\|Russo, A\|Surmacz, E\|Sulkowski, S
PMID:	17591803

61.
Journal:	Int J Cancer. 2007 Dec 1;121(11):2443-50.
Title:	Hypoxia upregulates carcinoembryonic antigen expression in cancer cells.
Author:	Kokkonen, Nina\|Ulibarri, Ines Fernandez\|Kauppila, Annika\|Luosujarvi, Hanne\|Rivinoja, Antti\|Pospiech, Helmut\|Kellokumpu, Ilmo\|Kellokumpu, Sakari
PMID:	17657737

62.
Journal:	Eur J Clin Invest. 2007 Nov;37(11):878-86. Epub 2007 Sep 20.
Title:	Activated VEGFR2/KDR pathway in tumour cells and tumour associated vessels of colorectal cancer.
Author:	Giatromanolaki, A\|Koukourakis, M I\|Sivridis, E\|Chlouverakis, G\|Vourvouhaki, E\|Turley, H\|Harris, A L\|Gatter, K C
PMID:	17883421

63.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Nov;10(6):561-4.
Title:	[Influence of artificial pneumoperitoneal media on colon carcinoma cell proliferation in vitro].
Author:	Tian, Yong-Gang\|Tang, Yin-Hua\|Xu, Jun\|Dai, Wen-Jie\|Liu, Su\|Zhao, Jin-Peng\|Ma, Yong\|Jiang, Hong-Chi
PMID:	18000780

64.
Journal:	Surg Oncol. 2007 Dec;16 Suppl 1:S25-7. Epub 2007 Nov 26.
Title:	Up-regulation and stabilization of HIF-1alpha in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18023174

65.
Journal:	Pharmacogenomics. 2007 Dec;8(12):1705-13.
Title:	Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients.
Author:	Azuma, Mizutomo\|Shi, Michael\|Danenberg, Kathleen D\|Gardner, Humphrey\|Barrett, Carl\|Jacques, Christian J\|Sherod, Andrew\|Iqbal, Syma\|El-Khoueiry, Anthony\|Yang, Dongyun\|Zhang, Wu\|Danenberg, Peter V\|Lenz, Heinz-Josef
PMID:	18086000

66.
Journal:	Korean J Gastroenterol. 2007 Jul;50(1):9-18.
Title:	[Expression of MMP-2, HIF-1alpha and VEGF in colon adenoma and colon cancer].
Author:	Shin, Jeong Eun\|Jung, Sung-Ae\|Kim, Seong-Eun\|Joo, Yang-Hee\|Shim, Ki-Nam\|Kim, Tae Hun\|Yoo, Kwon\|Moon, Il-Hwan
PMID:	18172354

67.
Journal:	Curr Med Chem. 2007;14(29):3122-38.
Title:	Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Author:	Stravopodis, Dimitrios J\|Margaritis, Lukas H\|Voutsinas, Gerassimos E
PMID:	18220746

68.
Journal:	J Exp Clin Cancer Res. 2007 Dec;26(4):515-9.
Title:	Increased VEGF165 expression in HCT116 colon cancer cells after transient transfection with a GFP vector encoding HIF-1 gene.
Author:	Lucarini, G\|Zizzi, A\|Belvederesi, L\|Kyriakidou, K\|Mazzucchelli, R\|Biagini, G
PMID:	18365547

69.
Journal:	Int J Cancer. 2008 Mar 15;122(6):1435-40.
Title:	Extracellular matrix and HIF-1 signaling: the role of prolidase.
Author:	Surazynski, Arkadiusz\|Donald, Steven P\|Cooper, Sandra K\|Whiteside, Martin A\|Salnikow, Konstantin\|Liu, Yongmin\|Phang, James M
PMID:	17999410

70.
Journal:	Cancer Res. 2008 Jan 1;68(1):285-91.
Title:	Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells.
Author:	Calvani, Maura\|Trisciuoglio, Daniela\|Bergamaschi, Cristina\|Shoemaker, Robert H\|Melillo, Giovanni
PMID:	18172321

71.
Journal:	Biochem Pharmacol. 2008 Feb 1;75(3):627-38.
Title:	Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis.
Author:	Selvakumaran, Muthu\|Yao, Kang Shen\|Feldman, Michael D\|O'Dwyer, Peter J
PMID:	18178171

72.
Journal:	Int J Oncol. 2008 Mar;32(3):585-92.
Title:	Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines.
Author:	Simiantonaki, Nektaria\|Jayasinghe, Caren\|Michel-Schmidt, Romi\|Peters, Kirsten\|Hermanns, Maria Iris\|Kirkpatrick, Charles James
PMID:	18292935

73.
Journal:	Virchows Arch. 2008 May;452(5):535-44.
Title:	Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Author:	Greijer, Astrid E\|Delis-van Diemen, Pien M\|Fijneman, Remond J A\|Giles, Rachel H\|Voest, Emile E\|van Hinsbergh, Victor W M\|Meijer, Gerrit A
PMID:	18351386

74.
Journal:	Clin Exp Metastasis. 2008;25(7):703-16.
Title:	Histone deacetylase inhibitors: the anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex).
Author:	Tarasenko, Nataly\|Nudelman, Abraham\|Tarasenko, Igor\|Entin-Meer, Michal\|Hass-Kogan, Daphne\|Inbal, Aida\|Rephaeli, Ada
PMID:	18506586

75.
Journal:	Int J Colorectal Dis. 2008 Nov;23(11):1049-55.
Title:	The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer.
Author:	Rajaganeshan, R\|Prasad, R\|Guillou, P J\|Poston, G\|Scott, N\|Jayne, D G
PMID:	18594846

76.
Journal:	Hum Pathol. 2008 Oct;39(10):1483-94.
Title:	Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Bertoni, Francesco\|Kwee, Ivo\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18619649

77.
Journal:	Mol Cancer Ther. 2008 Jul;7(7):1961-73.
Title:	Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity.
Author:	Sullivan, Richard\|Pare, Genevieve C\|Frederiksen, Lisa J\|Semenza, Gregg L\|Graham, Charles H
PMID:	18645006

78.
Journal:	Br J Cancer. 2008 Aug 5;99(3):459-63.
Title:	Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer.
Author:	Seenath, M M\|Roberts, D\|Cawthorne, C\|Saunders, M P\|Armstrong, G R\|O'Dwyer, S T\|Stratford, I J\|Dive, C\|Renehan, A G
PMID:	18648372

79.
Journal:	J Cell Biochem. 2008 Oct 1;105(2):546-53.
Title:	Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) through inhibiting protein synthesis.
Author:	Lee, Dae-Hee\|Lee, Yong J
PMID:	18655183

80.
Journal:	Biomed Pharmacother. 2008 Nov;62(9):613-21.
Title:	Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells.
Author:	Wu, Hongzhong\|Liang, Xin\|Fang, Yishi\|Qin, Xiaoran\|Zhang, Yuanxing\|Liu, Jianwen
PMID:	18674879

81.
Journal:	Int J Colorectal Dis. 2008 Nov;23(11):1057-64.
Title:	Role of Hypoxia-inducible factor-1 alpha and Survivin in colorectal carcinoma progression.
Author:	Fan, Li-Fang\|Dong, Wei-Guo\|Jiang, Cong-Qing\|Qian, Qun\|Yu, Qiong-Fang
PMID:	18704463

82.
Journal:	Carcinogenesis. 2008 Dec;29(12):2267-78.
Title:	Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells.
Author:	Cannito, Stefania\|Novo, Erica\|Compagnone, Alessandra\|Valfre di Bonzo, Lorenzo\|Busletta, Chiara\|Zamara, Elena\|Paternostro, Claudia\|Povero, Davide\|Bandino, Andrea\|Bozzo, Francesca\|Cravanzola, Carlo\|Bravoco, Vittoria\|Colombatto, Sebastiano\|Parola, Maurizio
PMID:	18791199

83.
Journal:	BMC Cancer. 2008 Nov 4;8:320.
Title:	Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression.
Author:	Simiantonaki, Nektaria\|Taxeidis, Marios\|Jayasinghe, Caren\|Kurzik-Dumke, Ursula\|Kirkpatrick, Charles James
PMID:	18983642

84.
Journal:	Oncol Rep. 2008 Dec;20(6):1321-7.
Title:	Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells.
Author:	Kim, Eun Soo\|Hong, Sung Yi\|Lee, Hye Kyung\|Kim, Seung Won\|An, Min Ji\|Kim, Tae Il\|Lee, Kyoung Ryul\|Kim, Won Ho\|Cheon, Jae Hee
PMID:	19020709

85.
Journal:	Hell J Nucl Med. 2008 Sep-Dec;11(3):146-8.
Title:	Highlights and prizes of an international meeting.
Author:	Grammaticos, Philip C
PMID:	19081855

86.
Journal:	Int J Cancer. 2009 Feb 15;124(4):763-71.
Title:	HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.
Author:	Imamura, Takaaki\|Kikuchi, Hirotoshi\|Herraiz, Maria-Teresa\|Park, Do-Youn\|Mizukami, Yusuke\|Mino-Kenduson, Mari\|Lynch, Maureen P\|Rueda, Bo R\|Benita, Yair\|Xavier, Ramnik J\|Chung, Daniel C
PMID:	19030186

87.
Journal:	Cancer Lett. 2009 Apr 18;276(2):143-51.
Title:	p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway.
Author:	Khromova, N V\|Kopnin, P B\|Stepanova, E V\|Agapova, L S\|Kopnin, B P
PMID:	19091459

88.
Journal:	Pathology. 2009;41(3):254-60.
Title:	Relations of TGF-beta1 with HIF-1 alpha, GLUT-1 and longer survival of colorectal cancer patients.
Author:	Sulkowska, Mariola\|Wincewicz, Andrzej\|Sulkowski, Stanislaw\|Koda, Mariusz\|Kanczuga-Koda, Luiza
PMID:	19142800

89.
Journal:	Eur J Cancer. 2009 Mar;45(5):890-8.
Title:	Effect of HIF-1 modulation on the response of two- and three-dimensional cultures of human colon cancer cells to 5-fluorouracil.
Author:	Ravizza, Raffaella\|Molteni, Roberta\|Gariboldi, Marzia B\|Marras, Emanuela\|Perletti, Gianpaolo\|Monti, Elena
PMID:	19171477

90.
Journal:	Clin Cancer Res. 2009 Feb 15;15(4):1297-307.
Title:	Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis.
Author:	Pencreach, Erwan\|Guerin, Eric\|Nicolet, Celine\|Lelong-Rebel, Isabelle\|Voegeli, Anne-Claire\|Oudet, Pierre\|Larsen, Annette K\|Gaub, Marie-Pierre\|Guenot, Dominique
PMID:	19190131

91.
Journal:	Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):1177-86.
Title:	Immunohistochemical detection of changes in tumor hypoxia.
Author:	Russell, James\|Carlin, Sean\|Burke, Sean A\|Wen, Bixiu\|Yang, Kwang Mo\|Ling, C Clifton
PMID:	19251089

92.
Journal:	Cancer Lett. 2009 Jul 8;279(2):221-9.
Title:	Cyclooxygenase-2 and Hypoxia-Inducible Factor-1alpha protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis.
Author:	Mariani, Francesco\|Sena, Paola\|Marzona, Laura\|Riccio, Massimo\|Fano, Rita\|Manni, Paola\|Gregorio, Carmela Di\|Pezzi, Annalisa\|Leon, Maurizio Ponz de\|Monni, Sebastiano\|Pol, Anto De\|Roncucci, Luca
PMID:	19268443

93.
Journal:	J Biol Chem. 2009 May 8;284(19):13033-44.
Title:	The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.
Author:	Kimbrel, Erin A\|Kung, Andrew L
PMID:	19297328

94.
Journal:	Br J Pharmacol. 2009 Apr;156(7):1054-66.
Title:	Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.
Author:	Riganti, C\|Doublier, S\|Viarisio, D\|Miraglia, E\|Pescarmona, G\|Ghigo, D\|Bosia, A
PMID:	19298255

95.
Journal:	Cell Death Differ. 2009 Sep;16(9):1203-14.
Title:	p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
Author:	Chiacchiera, F\|Matrone, A\|Ferrari, E\|Ingravallo, G\|Lo Sasso, G\|Murzilli, S\|Petruzzelli, M\|Salvatore, L\|Moschetta, A\|Simone, C
PMID:	19343039

96.
Journal:	Ann Surg. 2009 May;249(5):814-23.
Title:	Accelerated perinecrotic outgrowth of colorectal liver metastases following radiofrequency ablation is a hypoxia-driven phenomenon.
Author:	Nijkamp, Maarten W\|van der Bilt, Jarmila D W\|de Bruijn, Menno T\|Molenaar, I Quintus\|Voest, Emile E\|van Diest, Paul J\|Kranenburg, Onno\|Borel Rinkes, Inne H M
PMID:	19387320

97.
Journal:	Biochem Biophys Res Commun. 2009 Jul 17;385(1):16-21.
Title:	A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway.
Author:	Won, Mi-Sun\|Im, Namhui\|Park, Soohyun\|Boovanahalli, Shanthaveerappa K\|Jin, Yinglan\|Jin, Xuejun\|Chung, Kyung-Sook\|Kang, Moorim\|Lee, Kiho\|Park, Song-Kyu\|Kim, Hwan Mook\|Kwon, Byoung Mog\|Lee, Jung Joon\|Lee, Kyeong
PMID:	19433063

98.
Journal:	Mol Cancer Ther. 2009 May;8(5):1148-56.
Title:	Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment.
Author:	Burkitt, Kyunghee\|Chun, Sang Y\|Dang, Duyen T\|Dang, Long H
PMID:	19435875

99.
Journal:	Br J Cancer. 2009 May 19;100(10):1666-73.
Title:	Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis.
Author:	Rasheed, S\|Harris, A L\|Tekkis, P P\|Turley, H\|Silver, A\|McDonald, P J\|Talbot, I C\|Glynne-Jones, R\|Northover, J M A\|Guenther, T
PMID:	19436307

100.
Journal:	Int J Colorectal Dis. 2009 Nov;24(11):1287-96.
Title:	Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma.
Author:	Schmitz, Klaus Jurgen\|Muller, Carmen Ina\|Reis, Henning\|Alakus, Hakan\|Winde, Gunther\|Baba, Hideo Andreas\|Wohlschlaeger, Jeremias\|Jasani, Bharat\|Fandrey, Joachim\|Schmid, Kurt Werner
PMID:	19529947

101.
Journal:	Eur J Surg Oncol. 2009 Dec;35(12):1286-94.
Title:	Expression patterns of hypoxic markers at the invasive margin of colorectal cancers and liver metastases.
Author:	Rajaganeshan, R\|Prasad, R\|Guillou, P J\|Scott, N\|Poston, G\|Jayne, D G
PMID:	19540709

102.
Journal:	Autophagy. 2009 Oct;5(7):1030-3. Epub 2009 Oct 12.
Title:	Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism.
Author:	Chiacchiera, Fulvio\|Simone, Cristiano
PMID:	19587525

103.
Journal:	BMC Cancer. 2009 Jul 20;9:241.
Title:	GLUT1 gene is a potential hypoxic marker in colorectal cancer patients.
Author:	Chung, Fu-Yen\|Huang, Ming-Yii\|Yeh, Ching-Sheng\|Chang, Hui-Jen\|Cheng, Tian-Lu\|Yen, Li-Chen\|Wang, Jaw-Yuan\|Lin, Shiu-Ru
PMID:	19619276

104.
Journal:	Toxicol Appl Pharmacol. 2009 Nov 1;240(3):385-92.
Title:	Digoxin and ouabain induce P-glycoprotein by activating calmodulin kinase II and hypoxia-inducible factor-1alpha in human colon cancer cells.
Author:	Riganti, Chiara\|Campia, Ivana\|Polimeni, Manuela\|Pescarmona, Gianpiero\|Ghigo, Dario\|Bosia, Amalia
PMID:	19647009

105.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1390-8.
Title:	Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha.
Author:	Mori, Akira\|Moser, Christian\|Lang, Sven A\|Hackl, Christina\|Gottfried, Eva\|Kreutz, Marina\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	19671674

106.
Journal:	Br J Cancer. 2009 Oct 20;101(8):1290-7.
Title:	Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells.
Author:	Roberts, D L\|Williams, K J\|Cowen, R L\|Barathova, M\|Eustace, A J\|Brittain-Dissont, S\|Tilby, M J\|Pearson, D G\|Ottley, C J\|Stratford, I J\|Dive, C
PMID:	19755992

107.
Journal:	Clin Cancer Res. 2009 Nov 1;15(21):6619-29.
Title:	The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts.
Author:	Shannon, Aoife M\|Telfer, Brian A\|Smith, Paul D\|Babur, Muhammed\|Logie, Armelle\|Wilkinson, Robert W\|Debray, Camille\|Stratford, Ian J\|Williams, Kaye J\|Wedge, Stephen R
PMID:	19843666

108.
Journal:	Cancer Res. 2009 Nov 1;69(21):8499-506.
Title:	Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.
Author:	Kikuchi, Hirotoshi\|Pino, Maria S\|Zeng, Min\|Shirasawa, Senji\|Chung, Daniel C
PMID:	19843849

109.
Journal:	BMC Cancer. 2009 Dec 10;9:432.
Title:	Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications.
Author:	Cao, Dan\|Hou, Mei\|Guan, Yong-song\|Jiang, Ming\|Yang, Yu\|Gou, Hong-feng
PMID:	20003271

110.
Journal:	Zhonghua Zhong Liu Za Zhi. 2009 Oct;31(10):746-851.
Title:	[Combination with SN-38 on human colon cancer LoVo cells].
Author:	Wang, Yan\|Xu, Jian-ming\|Xu, Qin-zhi\|Zhou, Ping-kun\|Song, San-tai
PMID:	20021826

111.
Journal:	APMIS. 2009 Dec;117(12):880-5.
Title:	Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers.
Author:	Park, Sang Wook\|Chung, Nak Gyun\|Hur, Soo Young\|Kim, Ho Shik\|Yoo, Nam Jin\|Lee, Sug Hyung
PMID:	20078552

112.
Journal:	Pathol Oncol Res. 2010 Sep;16(3):311-8.
Title:	Comparison of beta-catenin with TGF-beta1, HIF-1alpha and patients' disease-free survival in human colorectal cancer.
Author:	Wincewicz, Andrzej\|Koda, Mariusz\|Sulkowski, Stanislaw\|Kanczuga-Koda, Luiza\|Sulkowska, Mariola
PMID:	19898961

113.
Journal:	Scand J Gastroenterol. 2010 Mar;45(3):340-8.
Title:	Preoperative radiotherapy downregulates the nuclear expression of hypoxia-inducible factor-1alpha in rectal cancer.
Author:	Korkeila, E\|Jaakkola, P M\|Syrjanen, K\|Sundstrom, J\|Pyrhonen, S
PMID:	20001759

114.
Journal:	Prostate Cancer Prostatic Dis. 2010 Jun;13(2):178-81.
Title:	Carbonic anhydrase IX expression in prostate cancer.
Author:	Smyth, L G\|O'Hurley, G\|O'Grady, A\|Fitzpatrick, J M\|Kay, E\|Watson, R W G
PMID:	20038959

115.
Journal:	Cancer Gene Ther. 2010 May;17(5):365-72.
Title:	Down-regulation of HIF-1alpha by oncolytic reovirus infection independently of VHL and p53.
Author:	Cho, I-R\|Koh, S S\|Min, H-J\|Park, E-H\|Ratakorn, S\|Jhun, B H\|Jeong, S H\|Yoo, Y H\|Youn, H D\|Johnston, R N\|Chung, Y-H
PMID:	20075985

116.
Journal:	Int J Gynecol Cancer. 2010 Feb;20(2):203-11.
Title:	p38alpha is required for ovarian cancer cell metabolism and survival.
Author:	Matrone, Antonio\|Grossi, Valentina\|Chiacchiera, Fulvio\|Fina, Emanuela\|Cappellari, Marianna\|Caringella, Anna Maria\|Di Naro, Edoardo\|Loverro, Giuseppe\|Simone, Cristiano
PMID:	20169663

117.
Journal:	J Cancer Res Clin Oncol. 2010 Nov;136(11):1697-707.
Title:	Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells.
Author:	Ding, Zhenyu\|Yang, Li\|Xie, Xiaodong\|Xie, Fangwei\|Pan, Feng\|Li, Jianjun\|He, Jianming\|Liang, Houjie
PMID:	20217131

118.
Journal:	Chem Biol Interact. 2010 May 14;185(3):247-52.
Title:	(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
Author:	Shimizu, Masahito\|Shirakami, Yohei\|Sakai, Hiroyasu\|Yasuda, Yoichi\|Kubota, Masaya\|Adachi, Seiji\|Tsurumi, Hisashi\|Hara, Yukihiko\|Moriwaki, Hisataka
PMID:	20346928

119.
Journal:	Am J Pathol. 2010 May;176(5):2292-301.
Title:	HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Chung, Daniel C\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20363910

120.
Journal:	J Gastroenterol. 2010 Aug;45(8):896-902.
Title:	CD133 expression is a potential prognostic indicator in intrahepatic cholangiocarcinoma.
Author:	Shimada, Mitsuo\|Sugimoto, Koji\|Iwahashi, Shuichi\|Utsunomiya, Tohru\|Morine, Yuji\|Imura, Satoru\|Ikemoto, Tetsuya
PMID:	20379837

121.
Journal:	Cancer Sci. 2010 Jun;101(6):1557-61.
Title:	Clinicopathological significance of nuclear factor-kappa B, HIF-1 alpha, and vascular endothelial growth factor expression in stage III colorectal cancer.
Author:	Kwon, Hyuk-Chan\|Kim, Sung Hyun\|Oh, Sung Yong\|Lee, Suee\|Kwon, Kyung A\|Lee, Jong Hoon\|Choi, Hong-Jo\|Park, Ki-Jae\|Lee, Hyung-Sik\|Roh, Mee Sook\|Kim, Hyo-Jin
PMID:	20398057

122.
Journal:	Carcinogenesis. 2010 Aug;31(8):1381-6.
Title:	Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.
Author:	Frank, Bernd\|Hoffmeister, Michael\|Klopp, Norman\|Illig, Thomas\|Chang-Claude, Jenny\|Brenner, Hermann
PMID:	20403915

123.
Journal:	Mol Cancer Res. 2010 May;8(5):643-52.
Title:	Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway.
Author:	Amir, Sharon\|Golan, Maya\|Mabjeesh, Nicola J
PMID:	20407014

124.
Journal:	Neoplasma. 2010;57(4):299-305.
Title:	Identification of differential proteins in colon cancer SW480 cells with HIF1-alpha silence by proteome analysis.
Author:	Wu, X Y\|Fu, Z X\|Wang, X H\|Shen, W
PMID:	20429620

125.
Journal:	BMC Cancer. 2010 Apr 30;10:175.
Title:	Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Author:	Chia, Jean-San\|Du, Jia-Ling\|Hsu, Wei-Bin\|Sun, Andy\|Chiang, Chun-Pin\|Wang, Won-Bo
PMID:	20429953

126.
Journal:	Cancer Res. 2010 May 15;70(10):4054-63.
Title:	Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells.
Author:	Kim, Sun-Hee\|Xia, Dianren\|Kim, Sang-Wook\|Holla, Vijaykumar\|Menter, David G\|Dubois, Raymond N
PMID:	20442290

127.
Journal:	J Pineal Res. 2010 Mar;48(2):178-84.
Title:	Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia.
Author:	Park, Shi-Young\|Jang, Won-Jun\|Yi, Eui-Yeun\|Jang, Ji-Yeong\|Jung, Yunjin\|Jeong, Joo-Won\|Kim, Yung-Jin
PMID:	20449875

128.
Journal:	Oncol Rep. 2010 Jul;24(1):97-104.
Title:	Hypoxia-inducible factor-1alpha modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer.
Author:	Zheng, Jianbao\|Sun, Xuejun\|Wang, Wei\|Lu, Shaoying
PMID:	20514449

129.
Journal:	Carcinogenesis. 2010 Aug;31(8):1367-75.
Title:	Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells.
Author:	Zhao, Xu-Yun\|Chen, Ting-Ting\|Xia, Li\|Guo, Meng\|Xu, Ying\|Yue, Fei\|Jiang, Yi\|Chen, Guo-Qiang\|Zhao, Ke-Wen
PMID:	20525878

130.
Journal:	Cancer Lett. 2010 Nov 1;297(1):75-83.
Title:	Sodium dichloroacetate (DCA) reduces apoptosis in colorectal tumor hypoxia.
Author:	Shahrzad, Siranoush\|Lacombe, Kristen\|Adamcic, Una\|Minhas, Kanwal\|Coomber, Brenda L
PMID:	20537792

131.
Journal:	Mol Carcinog. 2010 Sep;49(9):805-9.
Title:	Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk.
Author:	Knechtel, Gudrun\|Szkandera, Joanna\|Stotz, Michael\|Hofmann, Gunter\|Langsenlehner, Uwe\|Krippl, Peter\|Samonigg, Hellmut\|Renner, Wilfried\|Langner, Cord\|Dehchamani, Dadbeh\|Gerger, Armin
PMID:	20572162

132.
Journal:	Biochem Biophys Res Commun. 2010 Jul 23;398(2):205-11.
Title:	Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1alpha synthesis in HT-29 colon cancer cells.
Author:	Shin, Hyun-Woo\|Cho, Chung-Hyun\|Kim, Tae-You\|Park, Jong-Wan
PMID:	20599738

133.
Journal:	Biochem Pharmacol. 2010 Oct 1;80(7):982-9.
Title:	LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line.
Author:	Lee, Kyeong\|Kang, Jung Eun\|Park, Song-Kyu\|Jin, Yinglan\|Chung, Kyung-Sook\|Kim, Hwan-Mook\|Lee, Kiho\|Kang, Moo Rim\|Lee, Myung Kyu\|Song, Kyung Bin\|Yang, Eun-Gyeong\|Lee, Jung-Jun\|Won, Misun
PMID:	20599784

134.
Journal:	J Clin Invest. 2010 Aug;120(8):2699-714.
Title:	Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation.
Author:	Imtiyaz, Hongxia Z\|Williams, Emily P\|Hickey, Michele M\|Patel, Shetal A\|Durham, Amy C\|Yuan, Li-Jun\|Hammond, Rachel\|Gimotty, Phyllis A\|Keith, Brian\|Simon, M Celeste
PMID:	20644254

135.
Journal:	Anticancer Res. 2010 Jun;30(6):2393-7.
Title:	Association of hypoxia-inducible factor 1-alpha gene polymorphisms and colorectal cancer prognosis.
Author:	Szkandera, Joanna\|Knechtel, Gudrun\|Stotz, Michael\|Hofmann, Gunter\|Langsenlehner, Uwe\|Krippl, Peter\|Langsenlehner, Tanja\|Dehchamani, Dadbeh\|Samonigg, Hellmut\|Renner, Wilfried\|Gerger, Armin
PMID:	20651398

136.
Journal:	Oncogene. 2010 Oct 14;29(41):5568-78.
Title:	PIASy stimulates HIF1alpha SUMOylation and negatively regulates HIF1alpha activity in response to hypoxia.
Author:	Kang, X\|Li, J\|Zou, Y\|Yi, J\|Zhang, H\|Cao, M\|Yeh, E T H\|Cheng, J
PMID:	20661221

137.
Journal:	Cell Cycle. 2010 Jul 15;9(14):2803-13. Epub 2010 Jul 3.
Title:	FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways.
Author:	Rodriguez-Jimenez, Francisco Javier\|Moreno-Manzano, Victoria\|Mateos-Gregorio, Pablo\|Royo, Inmaculada\|Erceg, Slaven\|Murguia, Jose Ramon\|Sanchez-Puelles, Jose Maria
PMID:	20676050

138.
Journal:	Clin Cancer Res. 2010 Aug 15;16(16):4207-16.
Title:	Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.
Author:	Terzuoli, Erika\|Donnini, Sandra\|Giachetti, Antonio\|Iniguez, Miguel A\|Fresno, Manuel\|Melillo, Giovanni\|Ziche, Marina
PMID:	20682710

139.
Journal:	Biochim Biophys Acta. 2010 Nov;1803(11):1244-51.
Title:	Thymosin beta4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1alpha-dependent manner.
Author:	Jo, Jin-Ok\|Kim, Su-Ryun\|Bae, Moon-Kyung\|Kang, Yun-Jeong\|Ock, Mee Sun\|Kleinman, Hynda K\|Cha, Hee-Jae
PMID:	20691219

140.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1128-38.
Title:	The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.
Author:	Lin, Songbai\|Lee, Sei-Jung\|Shim, Hyunsuk\|Chun, Jerold\|Yun, C Chris
PMID:	20724530

141.
Journal:	Br J Cancer. 2010 Oct 12;103(8):1209-14.
Title:	Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia.
Author:	Koukourakis, M I\|Giatromanolaki, A\|Sivridis, E\|Pitiakoudis, M\|Gatter, K C\|Harris, A L
PMID:	20842118

142.
Journal:	Clin Dev Immunol. 2010;2010. pii: 537531.
Title:	Clinicopathologic significance of HIF-1alpha, CXCR4, and VEGF expression in colon cancer.
Author:	Wu, Yugang\|Jin, Min\|Xu, Huanbai\|Shimin, Zhang\|He, Songbing\|Wang, Liang\|Zhang, Yanyun
PMID:	20953377

143.
Journal:	Anticancer Res. 2010 Oct;30(10):4163-8.
Title:	Clinicopathological significance of p53, hypoxia-inducible factor 1alpha, and vascular endothelial growth factor expression in colorectal cancer.
Author:	Kwon, Hyuk-Chan\|Kim, Sung Hyun\|Oh, Sung Yong\|Lee, Suee\|Kwon, Kyung A\|Choi, Hong-Jo\|Park, Ki-Jae\|Kim, Hyo-Jin\|Roh, Mee Sook
PMID:	21036736

144.
Journal:	Mol Cancer. 2010 Nov 13;9:293.
Title:	Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1alpha and HIF-2alpha target genes.
Author:	Chun, Sang Y\|Johnson, Craig\|Washburn, Joseph G\|Cruz-Correa, Marcia R\|Dang, Duyen T\|Dang, Long H
PMID:	21073737

145.
Journal:	Radiat Oncol. 2010 Nov 15;5:107.
Title:	Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.
Author:	El-Khatib, Mona\|Geara, Fady\|Haddadin, Makhluf J\|Gali-Muhtasib, Hala
PMID:	21078189

146.
Journal:	Mol Med Rep. 2010 May-Jun;3(3):409-15.
Title:	Effect of hypoxia-inducible factor 1-alpha on Survivin in colorectal cancer.
Author:	Wu, Xing-Ye\|Fu, Zhong-Xue\|Wang, Xue-Hu
PMID:	21472255

147.
Journal:	Invest New Drugs. 2011 Apr;29(2):300-11.
Title:	Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4',5-trimethoxylstilbene-3'-O-phosphate disodium (M410).
Author:	Cai, Yu-Chen\|Zou, Yong\|Ye, Yan-Li\|Sun, Hong-Yi\|Su, Quan-Guan\|Wang, Zhi-Xin\|Zeng, Zhao-Lei\|Xian, Li-Jian
PMID:	20012336

148.
Journal:	Med Oncol. 2011 Dec;28(4):1032-7.
Title:	No association of the hypoxia-inducible factor-1alpha gene polymorphisms with survival in patients with colorectal cancer.
Author:	Lee, Soo Jung\|Kim, Jong Gwang\|Sohn, Sang Kyun\|Chae, Yee Soo\|Moon, Joon Ho\|Kang, Byung Woog\|Park, Jun Seok\|Park, Jin Young\|Choi, Gyu Seog
PMID:	20635169

149.
Journal:	J Cell Physiol. 2011 Apr;226(4):1060-8.
Title:	Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1alpha translational pathway in colorectal cancer cells.
Author:	Chang, Li-Hsun\|Chen, Chun-Han\|Huang, Der-Yi\|Pai, Hui-Chen\|Pan, Shiow-Lin\|Teng, Che-Ming
PMID:	20857420

150.
Journal:	Clin Oncol (R Coll Radiol). 2011 Jun;23(5):323-32.
Title:	Clinical significance of CD133 and hypoxia inducible factor-1alpha gene expression in rectal cancer after preoperative chemoradiotherapy.
Author:	Saigusa, S\|Tanaka, K\|Toiyama, Y\|Yokoe, T\|Okugawa, Y\|Koike, Y\|Fujikawa, H\|Inoue, Y\|Miki, C\|Kusunoki, M
PMID:	20970309

151.
Journal:	Oncogene. 2011 Feb 17;30(7):876-82.
Title:	Tumor-associated CpG demethylation augments hypoxia-induced effects by positive autoregulation of HIF-1alpha.
Author:	Koslowski, M\|Luxemburger, U\|Tureci, O\|Sahin, U
PMID:	21042279

152.
Journal:	J Hepatol. 2011 Feb;54(2):328-39.
Title:	Human carbonyl reductase 1 upregulated by hypoxia renders resistance to apoptosis in hepatocellular carcinoma cells.
Author:	Tak, Eunyoung\|Lee, Seonmin\|Lee, Jisun\|Rashid, M A\|Kim, Youn Wha\|Park, Jae-Hoon\|Park, Won Sang\|Shokat, Kevan M\|Ha, Joohun\|Kim, Sung Soo
PMID:	21056497

153.
Journal:	Cancer Res. 2011 Mar 1;71(5):1647-57.
Title:	The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Author:	Pez, Floriane\|Dayan, Frederic\|Durivault, Jerome\|Kaniewski, Bastien\|Aimond, Geraldine\|Le Provost, Gabrielle S\|Deux, Blandine\|Clezardin, Philippe\|Sommer, Pascal\|Pouyssegur, Jacques\|Reynaud, Caroline
PMID:	21239473

154.
Journal:	Cancer Res. 2011 Mar 15;71(6):2260-75.
Title:	NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1alpha.
Author:	Kim, Tae-Hyoung\|Hur, Eu-gene\|Kang, Su-Jin\|Kim, Jung-Ae\|Thapa, Dinesh\|Lee, You Mie\|Ku, Sae Kwang\|Jung, Yunjin\|Kwak, Mi-Kyoung
PMID:	21278237

155.
Journal:	BMC Cancer. 2011 Feb 1;11:51.
Title:	Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.
Author:	Abe, Masako\|Havre, Pamela A\|Urasaki, Yasuyo\|Ohnuma, Kei\|Morimoto, Chikao\|Dang, Long H\|Dang, Nam H
PMID:	21284881

156.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title:	Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author:	Liu, Xin\|Guo, Wei-Jian\|Zhang, Xiao-Wei\|Cai, Xu\|Tian, Shu\|Li, Jin
PMID:	21286718

157.
Journal:	Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4382-7.
Title:	Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.
Author:	Yeung, Trevor M\|Gandhi, Shaan C\|Bodmer, Walter F
PMID:	21368208

158.
Journal:	Anticancer Res. 2011 Feb;31(2):575-84.
Title:	Associations between single nucleotide polymorphisms of MMP2, VEGF, and HIF1A genes and the risk of developing colorectal cancer.
Author:	Kang, Min-Jung\|Jung, Sung-Ae\|Jung, Ji Min\|Kim, Seong-Eun\|Jung, Hye-Kyung\|Kim, Tae-Hun\|Shim, Ki-Nam\|Yi, Sun Young\|Yoo, Kwon\|Moon, Il Hwan
PMID:	21378341

159.
Journal:	Cell Death Dis. 2011 Mar 10;2:e128.
Title:	Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.
Author:	So, E Y\|Ausman, M\|Saeki, T\|Ouchi, T
PMID:	21390062

160.
Journal:	Int J Radiat Biol. 2011 Jun;87(6):579-90.
Title:	Honokiol inhibits hypoxia-inducible factor-1 pathway.
Author:	Lan, Keng-Li\|Lan, Keng-Hsin\|Sheu, Meei-Ling\|Chen, Ming-Yuan\|Shih, Yi-Sheng\|Hsu, Fu-Chih\|Wang, Hong-Ming\|Liu, Ren-Shyan\|Yen, Sang-Hue
PMID:	21473672

161.
Journal:	Cell Cycle. 2011 May 15;10(10):1545-7. Epub 2011 May 15.
Title:	Antagonistic crosstalk between APC and HIF-1alpha.
Author:	Nathke, Inke\|Rocha, Sonia
PMID:	21502812

162.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2011 Apr;31(4):705-6.
Title:	[Association of peripheral blood hypoxia-inducible factor-1alpha with metastasis of colorectal cancer].
Author:	Pan, Chun-Qiu\|Han, Shu-Ling\|Yu, Bi-Xiang\|Zeng, Can-Hui
PMID:	21515475

163.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Apr;14(4):284-7.
Title:	[Association of hypoxia-inducible factor 1alpha expression with microlymphatic vessel density and lymph node micrometastasis in rectal cancer].
Author:	Chang, Jia-cong\|Zhu, Guang-yu\|Yang, Jin-lei\|Zhang, Hong\|Wang, Dao-bin
PMID:	21538273

164.
Journal:	J Biol Chem. 2011 Jul 8;286(27):24089-100.
Title:	Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
Author:	Tammali, Ravinder\|Saxena, Ashish\|Srivastava, Satish K\|Ramana, Kota V
PMID:	21576240

165.
Journal:	J Biol Chem. 2011 Jul 15;286(28):25007-15.
Title:	Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer.
Author:	Liu, Yan\|Han, Zhi-peng\|Zhang, Shan-shan\|Jing, Ying-ying\|Bu, Xin-xin\|Wang, Chen-yang\|Sun, Kai\|Jiang, Guo-cheng\|Zhao, Xue\|Li, Rong\|Gao, Lu\|Zhao, Qiu-dong\|Wu, Meng-chao\|Wei, Li-xin
PMID:	21592963

166.
Journal:	Anticancer Res. 2011 May;31(5):1559-65.
Title:	Pretreatment HIF-1alpha and GLUT-1 expressions do not correlate with outcome after preoperative chemoradiotherapy in rectal cancer.
Author:	Havelund, Birgitte Mayland\|Sorensen, Flemming Brandt\|Lindebjerg, Jan\|Spindler, Karen-Lise Garm\|Jakobsen, Anders
PMID:	21617210

167.
Journal:	PLoS One. 2011;6(5):e20291.
Title:	MicroRNA-22 regulates hypoxia signaling in colon cancer cells.
Author:	Yamakuchi, Munekazu\|Yagi, Shusuke\|Ito, Takashi\|Lowenstein, Charles J
PMID:	21629773

168.
Journal:	Target Oncol. 2011 Sep;6(3):155-62.
Title:	LDH-A influences hypoxia-inducible factor 1alpha (HIF1 alpha) and is critical for growth of HT29 colon carcinoma cells in vivo.
Author:	Langhammer, Stefan\|Najjar, Maher\|Hess-Stumpp, Holger\|Thierauch, Karl-Heinz
PMID:	21660559

169.
Journal:	Chin J Integr Med. 2011 Jul;17(7):517-24.
Title:	In vitro antimetastatic effect of Changweiqing through antiinvasion of hypoxic colorectal carcinoma LoVo cells.
Author:	Li, Jing\|Fan, Zhong-Ze\|Sun, Jue\|Xu, Jian-Hua
PMID:	21725877

170.
Journal:	Cancer Microenviron. 2011 Aug;4(2):181-5.
Title:	The colorectal tumor microenvironment: the next decade.
Author:	Beauchemin, Nicole
PMID:	21735168

171.
Journal:	Hepatology. 2011 Nov;54(5):1661-78.
Title:	Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans.
Author:	Kim, Yeonghwan\|Jang, Miran\|Lim, Sangbin\|Won, Hyeran\|Yoon, Kyung-Sik\|Park, Jae-Hoon\|Kim, Hyo Jong\|Kim, Byung-Ho\|Park, Won-Sang\|Ha, Joohun\|Kim, Sung-Soo
PMID:	21748762

172.
Journal:	Am J Pathol. 2011 Sep;179(3):1405-14.
Title:	Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer.
Author:	Lu, Chun-Wun\|Lin, Shau-Chieh\|Chien, Chun-Wei\|Lin, Shih-Chieh\|Lee, Chung-Ta\|Lin, Bo-Wen\|Lee, Jenq-Chang\|Tsai, Shaw-Jenq
PMID:	21763680

173.
Journal:	Cancer Biol Ther. 2011 Oct 1;12(7):586-97. Epub 2011 Oct 1.
Title:	Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF) and angiogenesis.
Author:	Paradziej-Lukowicz, Jolanta\|Skwarska, Anna\|Peszynska-Sularz, Grazyna\|Brillowska-Dabrowska, Anna\|Konopa, Jerzy
PMID:	21775820

174.
Journal:	BMC Cancer. 2011 Aug 3;11:331.
Title:	Long-term exposure to hypoxia inhibits tumor progression of lung cancer in rats and mice.
Author:	Yu, Lunyin\|Hales, Charles A
PMID:	21812995

175.
Journal:	Mol Cancer Ther. 2011 Dec;10(12):2373-83.
Title:	The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells.
Author:	Klymenko, Tetyana\|Brandenburg, Martin\|Morrow, Christopher\|Dive, Caroline\|Makin, Guy
PMID:	22006676

176.
Journal:	J Radiat Res. 2011;52(6):821-7.
Title:	Expression of hypoxia-inducible factor 1alpha predicts clinical outcome after preoperative hyperthermo-chemoradiotherapy for locally advanced rectal cancer.
Author:	Shioya, Mariko\|Takahashi, Takeo\|Ishikawa, Hitoshi\|Sakurai, Hideyuki\|Ebara, Takeshi\|Suzuki, Yoshiyuki\|Saitoh, Jun-ichi\|Ohno, Tatsuya\|Asao, Takayuki\|Kuwano, Hiroyuki\|Nakano, Takashi
PMID:	22104271

177.
Journal:	Mol Cancer. 2011 Nov 23;10:144.
Title:	Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma.
Author:	Schulze, Daniel\|Plohmann, Philipp\|Hobel, Sabrina\|Aigner, Achim
PMID:	22111880

178.
Journal:	Anticancer Res. 2011 Dec;31(12):4529-35.
Title:	Carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 as predictors of disease outcome in rectal cancer: multivariate Cox survival models following data reduction by principal component analysis of the clinicopathological
Author:	Korkeila, Eija A\|Sundstrom, Jari\|Pyrhonen, Seppo\|Syrjanen, Kari
PMID:	22199327

179.
Journal:	Oncotarget. 2011 Dec;2(12):1191-202.
Title:	Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation.
Author:	Sheffer, Michal\|Simon, Amos J\|Jacob-Hirsch, Jasmine\|Rechavi, Gideon\|Domany, Eytan\|Givol, David\|D'Orazi, Gabriella
PMID:	22202117

180.
Journal:	Mol Carcinog. 2012 Nov;51(11):869-80.
Title:	A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author:	Park, Heesook\|Kim, Minhee\|Kwon, Gyoo Taik\|Lim, Do Young\|Yu, Rina\|Sung, Mi-Kyung\|Lee, Ki Won\|Daily, James W 3rd\|Park, Jung Han Yoon
PMID:	21919080

181.
Journal:	Mol Cell Biochem. 2012 Feb;361(1-2):235-41.
Title:	Thrombin-dependent modulation of beta1-integrin-mediated signaling up-regulates prolidase and HIF-1alpha through p-FAK in colorectal cancer cells.
Author:	Karna, Ewa\|Szoka, Lukasz\|Palka, Jerzy
PMID:	21993963

182.
Journal:	Mol Med. 2012 Feb 10;18:83-94.
Title:	In vivo topoisomerase I inhibition attenuates the expression of hypoxia-inducible factor 1alpha target genes and decreases tumor angiogenesis.
Author:	Guerin, Eric\|Raffelsberger, Wolfgang\|Pencreach, Erwan\|Maier, Armin\|Neuville, Agnes\|Schneider, Anne\|Bachellier, Philippe\|Rohr, Serge\|Petitprez, Amelie\|Poch, Olivier\|Moras, Dino\|Oudet, Pierre\|Larsen, Annette K\|Gaub, Marie-Pierre\|Guenot, Dominique
PMID:	22033674

183.
Journal:	J Gastrointest Surg. 2012 Feb;16(2):394-400.
Title:	Molecular mechanism underlying the detection of colorectal cancer by 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography.
Author:	Izuishi, Kunihiko\|Yamamoto, Yuka\|Sano, Takanori\|Takebayashi, Ryusuke\|Nishiyama, Yoshihiro\|Mori, Hirohito\|Masaki, Tsutomu\|Morishita, Asahiro\|Suzuki, Yasuyuki
PMID:	22065316

184.
Journal:	Cancer Res. 2012 Jan 1;72(1):304-14.
Title:	Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells.
Author:	Zhou, Yunfei\|Tozzi, Federico\|Chen, Jinyu\|Fan, Fan\|Xia, Ling\|Wang, Jinrong\|Gao, Guang\|Zhang, Aijun\|Xia, Xuefeng\|Brasher, Heather\|Widger, William\|Ellis, Lee M\|Weihua, Zhang
PMID:	22084398

185.
Journal:	Oncol Rep. 2012 Mar;27(3):727-33.
Title:	Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells.
Author:	Nassar, Zeyad D\|Aisha, Abdalrahim F A\|Idris, Norshirin\|Khadeer Ahamed, Mohamed B\|Ismail, Zhari\|Abu-Salah, Khalid M\|Alrokayan, Salman A\|Shah Abdul Majid, Amin Malik
PMID:	22134768

186.
Journal:	Ann Surg. 2012 Jan;255(1):86-94.
Title:	Angiogenesis in synchronous and metachronous colorectal liver metastases: the liver as a permissive soil.
Author:	van der Wal, Gesiena E\|Gouw, Annette S H\|Kamps, Jan A A M\|Moorlag, Henk E\|Bulthuis, Marian L C\|Molema, Grietje\|de Jong, Koert P
PMID:	22156924

187.
Journal:	Int J Mol Med. 2012 May;29(5):906-12.
Title:	Transforming growth factor-beta1 induces glutathione peroxidase-1 and protects from H2O2-induced cell death in colon cancer cells via the Smad2/ERK1/2/HIF-1alpha pathway.
Author:	Huang, Ying\|Fang, Wenfeng\|Wang, Yulei\|Yang, Wancai\|Xiong, Bin
PMID:	22307228

188.
Journal:	Biochim Biophys Acta. 2012 Apr;1823(4):889-99.
Title:	Down-regulation of MutS homolog 3 by hypoxia in human colorectal cancer.
Author:	Li, Jie\|Koike, Junichi\|Kugoh, Hiroyuki\|Arita, Michitsune\|Ohhira, Takahito\|Kikuchi, Yoshinori\|Funahashi, Kimihiko\|Takamatsu, Ken\|Boland, C Richard\|Koi, Minoru\|Hemmi, Hiromichi
PMID:	22343000

189.
Journal:	Anticancer Res. 2012 Mar;32(3):865-72.
Title:	SN-38 overcomes chemoresistance of colorectal cancer cells induced by hypoxia, through HIF1alpha.
Author:	Murono, Koji\|Tsuno, Nelson H\|Kawai, Kazushige\|Sasaki, Kazuhito\|Hongo, Kumiko\|Kaneko, Manabu\|Hiyoshi, Masaya\|Tada, Noriko\|Nirei, Takako\|Sunami, Eiji\|Takahashi, Koki\|Kitayama, Joji
PMID:	22399605

190.
Journal:	Exp Mol Pathol. 2012 Jun;92(3):296-303.
Title:	Overexpression of nuclear NHERF1 in advanced colorectal cancer: association with hypoxic microenvironment and tumor invasive phenotype.
Author:	Malfettone, Andrea\|Silvestris, Nicola\|Paradiso, Angelo\|Mattioli, Eliseo\|Simone, Giovanni\|Mangia, Annita
PMID:	22440733

191.
Journal:	Biochem Biophys Res Commun. 2012 Apr 20;420(4):913-7.
Title:	Hypoxia-inducible factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells.
Author:	Ao, Jin-e\|Kuang, Liang-hong\|Zhou, Yu\|Zhao, Rong\|Yang, Chang-ming
PMID:	22475487

192.
Journal:	Mutat Res. 2012 Jun 1;734(1-2):30-40.
Title:	Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Welbourn, Bill\|Wolff, Roger K\|Corcoran, Christopher
PMID:	22531693

193.
Journal:	Biol Pharm Bull. 2012;35(6):924-32.
Title:	Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia-inducible factor-1alpha activation.
Author:	Thapa, Dinesh\|Kang, Youra\|Park, Pil-Hoon\|Noh, Seok Kyun\|Lee, Yong Rok\|Han, Sung Soo\|Ku, Sae Kwang\|Jung, Yunjin\|Kim, Jung-Ae
PMID:	22687485

194.
Journal:	Oncol Rep. 2012 Sep;28(3):855-61.
Title:	Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Author:	Saigusa, Susumu\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Hiro, Junichiro\|Inoue, Yasuhiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22711167

195.
Journal:	Cancer Discov. 2012 Jul;2(7):608-23.
Title:	The HIF-1alpha hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy.
Author:	Palazon, Asis\|Martinez-Forero, Ivan\|Teijeira, Alvaro\|Morales-Kastresana, Aizea\|Alfaro, Carlos\|Sanmamed, Miguel F\|Perez-Gracia, Jose Luis\|Penuelas, Ivan\|Hervas-Stubbs, Sandra\|Rouzaut, Ana\|de Landazuri, Manuel Ortiz\|Jure-Kunkel, Maria\|Aragones, Julian\|Meler
PMID:	22719018

196.
Journal:	Carcinogenesis. 2012 Sep;33(9):1664-73.
Title:	HIF-1alpha-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism.
Author:	Fu, Linna\|Chen, Lisha\|Yang, Jie\|Ye, Ting\|Chen, Yingxuan\|Fang, Jingyuan
PMID:	22745382

197.
Journal:	Exp Biol Med (Maywood). 2012 Jul;237(7):860-6.
Title:	Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer.
Author:	Xie, Ganfeng\|Zheng, Lei\|Ou, Juanjuan\|Huang, Haihui\|He, Jinxia\|Li, Jianjun\|Pan, Feng\|Liang, Houjie
PMID:	22802519

198.
Journal:	BMC Cancer. 2012 Jul 17;12:293.
Title:	Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
Author:	Chintala, Sreenivasulu\|Najrana, Tanbir\|Toth, Karoly\|Cao, Shousong\|Durrani, Farukh A\|Pili, Roberto\|Rustum, Youcef M
PMID:	22804960

199.
Journal:	Virchows Arch. 2012 Sep;461(3):231-43.
Title:	Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer : future possibilities for personalised treatment by use of biomarkers.
Author:	de Cuba, E M V\|Kwakman, R\|van Egmond, M\|Bosch, L J W\|Bonjer, H J\|Meijer, G A\|te Velde, E A
PMID:	22825001

200.
Journal:	Anticancer Res. 2012 Aug;32(8):3299-303.
Title:	Main effects and interactions of carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 in multivariate analysis for disease outcome in rectal cancer.
Author:	Korkeila, Eija\|Sundstrom, Jari\|Pyrhonen, Seppo\|Syrjanen, Kari
PMID:	22843905

201.
Journal:	BMC Cancer. 2012 Aug 1;12:331.
Title:	A systems biology approach to the global analysis of transcription factors in colorectal cancer.
Author:	Pradhan, Meeta P\|Prasad, Nagendra K A\|Palakal, Mathew J
PMID:	22852817

202.
Journal:	Toxicol Sci. 2012 Dec;130(2):269-80.
Title:	Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathway.
Author:	Wang, Lei\|Son, Young-Ok\|Ding, Songze\|Wang, Xin\|Hitron, John Andrew\|Budhraja, Amit\|Lee, Jeong-Chae\|Lin, Qinchen\|Poyil, Pratheeshkumar\|Zhang, Zhuo\|Luo, Jia\|Shi, Xianglin
PMID:	22872060

203.
Journal:	Dis Colon Rectum. 2012 Sep;55(9):990-5.
Title:	Hypoxia-related proteins in patients with rectal cancer undergoing neoadjuvant combined modality therapy.
Author:	Lee-Kong, Steven A\|Ruby, Jeannine A\|Chessin, David B\|Pucciarelli, Salvatore\|Shia, Jinru\|Riedel, Elyn R\|Nitti, Donato\|Guillem, Jose G
PMID:	22874607

204.
Journal:	Int J Oncol. 2012 Nov;41(5):1715-22.
Title:	Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer.
Author:	Hong, Sang-Won\|Jung, Kyung Hee\|Choi, Myung-Joo\|Kim, Da Young\|Lee, Hee-Seung\|Zheng, Hong-Mei\|Li, Guang Yong\|El-Deeb, Ibrahim M\|Park, Byung Sun\|Lee, So Ha\|Hong, Soon-Sun
PMID:	22941304

205.
Journal:	Biosci Rep. 2012 Dec;32(6):587-95.
Title:	Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling.
Author:	Zhdanov, Alexander V\|Dmitriev, Ruslan I\|Papkovsky, Dmitri B
PMID:	22943412

206.
Journal:	Oncol Rep. 2012 Nov;28(5):1701-8.
Title:	Expression of endothelial cell-specific molecule-1 regulated by hypoxia inducible factor-1alpha in human colon carcinoma: impact of ESM-1 on prognosis and its correlation with clinicopathological features.
Author:	Kim, Joo Heon\|Park, Mee Young\|Kim, Chang Nam\|Kim, Kyo Hyun\|Kang, Ho Bum\|Kim, Kwang Dong\|Kim, Jae Wha
PMID:	22948784

207.
Journal:	Chem Res Toxicol. 2012 Oct 15;25(10):2194-202.
Title:	Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1alpha stabilization in colon carcinoma cells.
Author:	Chowdhury, Rajdeep\|Godoy, Luiz C\|Thiantanawat, Apinya\|Trudel, Laura J\|Deen, William M\|Wogan, Gerald N
PMID:	22971010

208.
Journal:	BMC Complement Altern Med. 2012 Sep 19;12:160.
Title:	Astragalus saponins downregulate vascular endothelial growth factor under cobalt chloride-stimulated hypoxia in colon cancer cells.
Author:	Law, Pui-Ching\|Auyeung, Kathy K\|Chan, Lok-Yi\|Ko, Joshua K
PMID:	22992293

209.
Journal:	PLoS One. 2012;7(9):e44658. Epub 2012 Sep 14.
Title:	Dietary administration of scallion extract effectively inhibits colorectal tumor growth: cellular and molecular mechanisms in mice.
Author:	Arulselvan, Palanisamy\|Wen, Chih-Chun\|Lan, Chun-Wen\|Chen, Yung-Hsiang\|Wei, Wen-Chi\|Yang, Ning-Sun
PMID:	23024755

210.
Journal:	Oncol Lett. 2012 Nov;4(5):1056-1060.
Title:	Single nucleotide polymorphisms in the HIF-1alpha gene and chemoradiotherapy of locally advanced rectal cancer.
Author:	Havelund, Birgitte Mayland\|Spindler, Karen-Lise Garm\|Ploen, John\|Andersen, Rikke Fredslund\|Jakobsen, Anders
PMID:	23162650

211.
Journal:	Exp Ther Med. 2012 Sep;4(3):370-374.
Title:	Polysaccharide K suppresses angiogenesis in colon cancer cells.
Author:	Satoh, Yoshiki\|Goi, Takanori\|Nakazawa, Toshiyuki\|Kimura, Youhei\|Hirono, Yasuo\|Katayama, Kanji\|Yamaguchi, Akio
PMID:	23181101

212.
Journal:	Pharmacogenomics J. 2013 Oct;13(5):410-6.
Title:	Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
Author:	Wilson, P M\|Yang, D\|Azuma, M\|Shi, M M\|Danenberg, K D\|Lebwohl, D\|Sherrod, A\|Ladner, R D\|Zhang, W\|Danenberg, P V\|Trarbach, T\|Folprecht, G\|Meinhardt, G\|Lenz, H-J
PMID:	22664478

213.
Journal:	Int J Colorectal Dis. 2013 Mar;28(3):375-83.
Title:	Glucose transporter 1 (GLUT1) of anaerobic glycolysis as predictive and prognostic values in neoadjuvant chemoradiotherapy and laparoscopic surgery for locally advanced rectal cancer.
Author:	Shim, Byoung Yong\|Jung, Ji-Han\|Lee, Kang-Moon\|Kim, Hyung-Jin\|Hong, Sook Hee\|Kim, Sung Hwan\|Sun, Der Sheng\|Cho, Hyeon-Min
PMID:	22847606

214.
Journal:	Food Chem. 2013 Jan 1;136(1):26-33.
Title:	SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway.
Author:	Son, Mi Kwon\|Jung, Kyung Hee\|Hong, Sang-Won\|Lee, Hee-Seung\|Zheng, Hong-Mei\|Choi, Myung-Joo\|Seo, Ju Hyeon\|Suh, Jun-Kyu\|Hong, Soon-Sun
PMID:	23017388

215.
Journal:	APMIS. 2013 Feb;121(2):127-38.
Title:	Immunohistological expression of HIF-1alpha, GLUT-1, Bcl-2 and Ki-67 in consecutive biopsies during chemoradiotherapy in patients with rectal cancer.
Author:	Havelund, Birgitte Mayland\|Sorensen, Flemming Brandt\|Ploen, John\|Lindebjerg, Jan\|Spindler, Karen-Lise Garm\|Jakobsen, Anders
PMID:	23030583

216.
Journal:	Oncogene. 2013 Sep 5;32(36):4313-8.
Title:	Increasing the oxygen load by treatment with myo-inositol trispyrophosphate reduces growth of colon cancer and modulates the intestine homeobox gene Cdx2.
Author:	Derbal-Wolfrom, L\|Pencreach, E\|Saandi, T\|Aprahamian, M\|Martin, E\|Greferath, R\|Tufa, E\|Choquet, P\|Lehn, J-M\|Nicolau, C\|Duluc, I\|Freund, J-N
PMID:	23045284

217.
Journal:	Appl Immunohistochem Mol Morphol. 2013 Jul;21(4):298-307.
Title:	The influence of tissue ischemia on biomarker expression in colorectal cancer.
Author:	Havelund, Birgitte M\|Olsen, Dorte A\|Andersen, Rikke F\|Spindler, Karen-Lise G\|Brandslund, Ivan\|Jakobsen, Anders\|Soerensen, Flemming B
PMID:	23060299

218.
Journal:	Cancer Res. 2013 Feb 15;73(4):1386-99.
Title:	Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment.
Author:	Isaacs, John T\|Antony, Lizamma\|Dalrymple, Susan L\|Brennen, W Nathaniel\|Gerber, Stephanie\|Hammers, Hans\|Wissing, Michel\|Kachhap, Sushant\|Luo, Jun\|Xing, Li\|Bjork, Per\|Olsson, Anders\|Bjork, Anders\|Leanderson, Tomas
PMID:	23149916

219.
Journal:	Biochem Biophys Res Commun. 2013 Jan 11;430(2):505-11.
Title:	c-Myc enhances colon cancer cell-mediated angiogenesis through the regulation of HIF-1alpha.
Author:	Chen, Cheng\|Cai, Shaoxin\|Wang, Guihua\|Cao, Xiaonian\|Yang, Xi\|Luo, Xuelai\|Feng, Yongdong\|Hu, Junbo
PMID:	23237807

220.
Journal:	Eur J Pharmacol. 2013 Jan 15;699(1-3):124-31.
Title:	Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1alpha protein by inhibiting HIF prolyl hydroxylase.
Author:	Yum, Soohwan\|Doh, Hea-Jeong\|Hong, Sungchae\|Jeong, Seongkeun\|Kim, Dae-Duk\|Park, Misun\|Jung, Yunjin
PMID:	23261967

221.
Journal:	Mol Imaging. 2013 Jan-Feb;12(1):49-58.
Title:	Pharmacologic activation of tumor hypoxia: a means to increase tumor 2-deoxy-2-[18F]fluoro-D-glucose uptake?
Author:	Mees, Gilles\|Dierckx, Rudi\|Vangestel, Christel\|Laukens, Debby\|Van Damme, Nancy\|Van de Wiele, Christophe
PMID:	23348791

222.
Journal:	Angiogenesis. 2013 Jul;16(3):561-73.
Title:	p55PIK-PI3K stimulates angiogenesis in colorectal cancer cell by activating NF-kappaB pathway.
Author:	Wang, Guihua\|Chen, Cheng\|Yang, Rui\|Cao, Xiaonian\|Lai, Senyan\|Luo, Xuelai\|Feng, Yongdong\|Xia, Xianmin\|Gong, Jianping\|Hu, Junbo
PMID:	23354733

223.
Journal:	Nutr Cancer. 2013;65(1):147-56.
Title:	Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1alpha.
Author:	Cardeno, Ana\|Sanchez-Hidalgo, Marina\|Rosillo, M Angeles\|Alarcon de la Lastra, Catalina
PMID:	23368925

224.
Journal:	EMBO Mol Med. 2013 Mar;5(3):366-83.
Title:	A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-alpha.
Author:	Begley, Ulrike\|Sosa, Maria Soledad\|Avivar-Valderas, Alvaro\|Patil, Ashish\|Endres, Lauren\|Estrada, Yeriel\|Chan, Clement T Y\|Su, Dan\|Dedon, Peter C\|Aguirre-Ghiso, Julio A\|Begley, Thomas
PMID:	23381944

225.
Journal:	Bioorg Med Chem. 2013 Apr 1;21(7):2135-44.
Title:	Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy.
Author:	Schmitt, Celine\|Voegelin, Manon\|Marin, Aurelie\|Schmitt, Marjorie\|Schegg, Fabienne\|Henon, Philippe\|Guenot, Dominique\|Tarnus, Celine
PMID:	23428964

226.
Journal:	Free Radic Biol Med. 2013 Jul;60:201-10.
Title:	Mad1 mediates hypoxia-induced doxorubicin resistance in colon cancer cells by inhibiting mitochondrial function.
Author:	Cho, Kumsun\|Shin, Hyun-Woo\|Kim, Young-Im\|Cho, Chung-Hyun\|Chun, Yang-Sook\|Kim, Tae-You\|Park, Jong-Wan
PMID:	23459071

227.
Journal:	Evid Based Complement Alternat Med. 2013;2013:974313.
Title:	Activation of AMP-Activated Protein Kinase alpha and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells.
Author:	Cho, Sung-Yun\|Lee, Hyo-Jeong\|Lee, Hyo-Jung\|Jung, Deok-Beom\|Kim, Hyunseok\|Sohn, Eun Jung\|Kim, Bonglee\|Jung, Ji Hoon\|Kwon, Byoung-Mog\|Kim, Sung-Hoon
PMID:	23589723

228.
Journal:	J Biomol Screen. 2013 Aug;18(7):782-96.
Title:	A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-kappaB pathway.
Author:	Pan, Jing\|Zhang, Jing\|Hill, Andrew\|Lapan, Peter\|Berasi, Steve\|Bates, Brian\|Miller, Christopher\|Haney, Steven
PMID:	23591012

229.
Journal:	Cell Death Dis. 2013 May 2;4:e622.
Title:	Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells.
Author:	Huang, C-Y\|Kuo, W-T\|Huang, Y-C\|Lee, T-C\|Yu, L C H
PMID:	23640464

230.
Journal:	BMC Cancer. 2013 May 7;13:229.
Title:	Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells.
Author:	Yamagishi, Naoko\|Teshima-Kondo, Shigetada\|Masuda, Kiyoshi\|Nishida, Kensei\|Kuwano, Yuki\|Dang, Duyen T\|Dang, Long H\|Nikawa, Takeshi\|Rokutan, Kazuhito
PMID:	23651517

231.
Journal:	Int J Oncol. 2013 Aug;43(2):586-90.
Title:	Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.
Author:	Ahmad, Sufian S\|Glatzle, Jorg\|Bajaeifer, Khaled\|Buhler, Sarah\|Lehmann, Thorsten\|Konigsrainer, Ingmar\|Vollmer, Jorg-Peter\|Sipos, Bence\|Ahmad, Suhaib S\|Northoff, Hinnak\|Konigsrainer, Alfred\|Zieker, Derek
PMID:	23727790

232.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S527-36.
Title:	Overexpression of hypoxia inducible factor-1 alpha is an independent risk factor for recurrence after curative resection of colorectal liver metastases.
Author:	Shimomura, Manabu\|Hinoi, Takao\|Kuroda, Shintaro\|Adachi, Tomohiro\|Kawaguchi, Yasuo\|Sasada, Tatsunari\|Takakura, Yuji\|Egi, Hiroyuki\|Okajima, Masazumi\|Tashiro, Hirotaka\|Nishizaka, Takashi\|Ohdan, Hideki
PMID:	23748663

233.
Journal:	J Surg Res. 2013 Nov;185(1):264-72.
Title:	Glucose-regulated protein 78 silencing down-regulates vascular endothelial growth factor/vascular endothelial growth factor receptor 2 pathway to suppress human colon cancer tumor growth.
Author:	Kuo, Li-Jen\|Hung, Chin-Sheng\|Chen, Wei-Yu\|Chang, Yu-Jia\|Wei, Po-Li
PMID:	23759331

234.
Journal:	Cancer Lett. 2013 Oct 28;340(1):22-9.
Title:	P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1alpha.
Author:	Liu, Kevin H\|Huynh, Nhi\|Patel, Oneel\|Shulkes, Arthur\|Baldwin, Graham\|He, Hong
PMID:	23811286

235.
Journal:	Angiogenesis. 2013 Oct;16(4):903-17.
Title:	Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1alpha and STAT-3.
Author:	Nagaraju, Ganji Purnachandra\|Park, Wungki\|Wen, Jing\|Mahaseth, Hemchandra\|Landry, Jerome\|Farris, Alton B\|Willingham, Field\|Sullivan, Patrick S\|Proia, David A\|El-Hariry, Iman\|Taliaferro-Smith, Latonia\|Diaz, Roberto\|El-Rayes, Bassel F
PMID:	23838996

236.
Journal:	PLoS One. 2013 Jun 20;8(6):e66255.
Title:	hypoxia-inducible factors activate CD133 promoter through ETS family transcription factors.
Author:	Ohnishi, Shunsuke\|Maehara, Osamu\|Nakagawa, Koji\|Kameya, Ayano\|Otaki, Kanako\|Fujita, Hirotoshi\|Higashi, Ryosuke\|Takagi, Kikuko\|Asaka, Masahiro\|Sakamoto, Naoya\|Kobayashi, Masanobu\|Takeda, Hiroshi
PMID:	23840432

237.
Journal:	Mol Cancer. 2013 Jul 17;12:78.
Title:	TNFalpha and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells.
Author:	Straus, Daniel S
PMID:	23866118

238.
Journal:	Food Chem. 2013 Dec 1;141(3):1841-6.
Title:	Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1alpha and VEGF expression in human glioma cells.
Author:	Gupta, Brinda\|Chiang, Linda\|Chae, KyungMin\|Lee, Dae-Hee
PMID:	23870899

239.
Journal:	J Biol Chem. 2013 Aug 30;288(35):25244-53.
Title:	Regulation of hypoxia-inducible factor 1alpha (HIF-1alpha) by lysophosphatidic acid is dependent on interplay between p53 and Kruppel-like factor 5.
Author:	Lee, Sei-Jung\|No, Yi Ran\|Dang, Duyen T\|Dang, Long H\|Yang, Vincent W\|Shim, Hyunsuk\|Yun, C Chris
PMID:	23880760

240.
Journal:	Cancer Lett. 2013 Dec 1;341(2):159-65.
Title:	HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.
Author:	Kim, Sun-Hee\|Wang, Dingzhi\|Park, Yun-Yong\|Katoh, Hiroshi\|Margalit, Ofer\|Sheffer, Michal\|Wu, Hong\|Holla, Vijaykumar R\|Lee, Ju-Seog\|DuBois, Raymond N
PMID:	23916472

241.
Journal:	PLoS One. 2013 Jul 29;8(7):e69660.
Title:	Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma.
Author:	Al-Greene, Nicole T\|Means, Anna L\|Lu, Pengcheng\|Jiang, Aixiang\|Schmidt, Carl R\|Chakravarthy, A Bapsi\|Merchant, Nipun B\|Washington, M Kay\|Zhang, Bing\|Shyr, Yu\|Deane, Natasha G\|Beauchamp, R Daniel
PMID:	23922772

242.
Journal:	Cancer Med. 2013 Jun;2(3):277-85.
Title:	Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Townsend, Amanda R\|Wrin, Joseph W\|Wilson, Kate\|Weickhardt, Andrew\|Simes, Robert J\|Murone, Carmel\|Tebbutt, Niall C
PMID:	23930204

243.
Journal:	Mol Med Rep. 2013 Oct;8(4):1017-22.
Title:	hClock gene expression in human colorectal carcinoma.
Author:	Wang, Liying\|Chen, Bozan\|Wang, Yaping\|Sun, Ning\|Lu, Chao\|Qian, Ruizhe\|Hua, Luchun
PMID:	23970287

244.
Journal:	Mol Cell Biol. 2013 Nov;33(22):4594-605.
Title:	Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells.
Author:	Wen, Yang-An\|Stevens, Payton D\|Gasser, Michael L\|Andrei, Romina\|Gao, Tianyan
PMID:	24061475

245.
Journal:	Anticancer Agents Med Chem. 2013 Nov;13(9):1460-6.
Title:	Discovery of P3971 an orally efficacious novel anticancer agent targeting HIF-1alpha and STAT3 pathways.
Author:	Godse, Pallavi\|Kumar, Pramod\|Yewalkar, Nilambari\|Deore, Vijaykumar\|Lohar, Manoj\|Mundada, Ramswaroop\|Padgaonkar, Amol\|Manohar, Sonal\|Joshi, Asavari\|Bhatia, Dimple\|Desai, Nikesh\|Damre, Anagha\|Bhonde, Mandar\|Joshi, Kalpana\|Sharma, Rajiv\|Kumar, Sanjay
PMID:	24102269

246.
Journal:	Digestion. 2013;88(3):182-92.
Title:	Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer.
Author:	Bentz, S\|Cee, A\|Endlicher, E\|Wojtal, K A\|Naami, A\|Pesch, T\|Lang, S\|Schubert, P\|Fried, M\|Weber, A\|Coy, J F\|Goelder, S\|Knuchel, R\|Hausmann, M\|Rogler, G
PMID:	24193262

247.
Journal:	Oncol Lett. 2013 Dec;6(6):1631-1635.
Title:	Prognostic value of Annexin A3 in human colorectal cancer and its correlation with hypoxia-inducible factor-1alpha
Author:	Xie, Yong-Qiu\|Fu, DI\|He, Zheng-Hua\|Tan, Qing-Dong
PMID:	24260057

248.
Journal:	PLoS One. 2013 Dec 6;8(12):e80337.
Title:	Prognostic value and clinicopathological differences of HIFs in colorectal cancer: evidence from meta-analysis.
Author:	Chen, Zhigang\|He, Xin\|Xia, Wenjie\|Huang, Qi\|Zhang, Zhigang\|Ye, Jun\|Ni, Chao\|Wu, Pin\|Wu, Dang\|Xu, Jinghong\|Qiu, Fuming\|Huang, Jian
PMID:	24324596

249.
Journal:	Int J Endocrinol. 2013;2013:453898.
Title:	Estrogen inhibits colon polyp formation by reducing angiogenesis in a carcinogen-induced rat model.
Author:	Yang, Jia\|Xiong, Li-Juan\|Xu, Fei\|Zhao, Xiang\|Liu, Bo\|Cai, Kai-Lin\|Wang, Guo-Bin
PMID:	24348555

250.
Journal:	Folia Histochem Cytobiol. 2013;51(4):320-5.
Title:	The relationships between hypoxia-dependent markers: HIF-1alpha, EPO and EPOR in colorectal cancer.
Author:	Baltaziak, Marek\|Wincewicz, Andrzej\|Kanczuga-Koda, Luiza\|Lotowska, Joanna M\|Koda, Mariusz\|Sulkowska, Urszula\|Baltaziak, Marcin\|Podbielski, Monika\|Sobaniec-Lotowska, Maria E\|Sulkowski, Stanislaw
PMID:	24497137

251.
Journal:	Mol Carcinog. 2014 Feb;53 Suppl 1:E107-18.
Title:	Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway.
Author:	Wang, Hu\|Zhao, Li\|Zhu, Li-Tao\|Wang, Yu\|Pan, Di\|Yao, Jing\|You, Qi-Dong\|Guo, Qing-Long
PMID:	23761018

252.
Journal:	Endocr Relat Cancer. 2013 Dec 20;21(1):73-84.
Title:	GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction.
Author:	Huang, Ssu-Ming\|Chen, Tzu-Sheng\|Chiu, Chien-Ming\|Chang, Leang-Kai\|Liao, Kuan-Fu\|Tan, Hsiao-Ming\|Yeh, Wei-Lan\|Chang, Gary Ro-Lin\|Wang, Min-Ying\|Lu, Dah-Yuu
PMID:	24165321

253.
Journal:	Oncol Rep. 2014 Jan;31(1):111-6.
Title:	Deferoxamine enhances cell migration and invasion through promotion of HIF-1alpha expression and epithelial-mesenchymal transition in colorectal cancer.
Author:	Zhang, Wenjing\|Wu, Yao\|Yan, Qingqing\|Ma, Feng\|Shi, Xinpeng\|Zhao, Yingying\|Peng, Ying\|Wang, Jide\|Jiang, Bo
PMID:	24173124

254.
Journal:	Oncol Rep. 2014 Feb;31(2):737-44.
Title:	Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells.
Author:	Chen, Liang\|Kang, Qiao-Hui\|Chen, Ying\|Zhang, Ya-Hong\|Li, Qian\|Xie, Song-Qiang\|Wang, Chao-Jie
PMID:	24297510

255.
Journal:	Carcinogenesis. 2014 May;35(5):983-91.
Title:	CHIP/Stub1 functions as a tumor suppressor and represses NF-kappaB-mediated signaling in colorectal cancer.
Author:	Wang, Yangmeng\|Ren, Fangli\|Wang, Yinyin\|Feng, Yarui\|Wang, Dianjun\|Jia, Baoqing\|Qiu, Ying\|Wang, Shiyan\|Yu, Jun\|Sung, Joseph Jy\|Xu, Jiake\|Zeps, Nikolajs\|Chang, Zhijie
PMID:	24302614

256.
Journal:	Eur J Cardiothorac Surg. 2014 Jul;46(1):92-9.
Title:	Carbonic anhydrase IX is associated with early pulmonary spreading of primary colorectal carcinoma and tobacco smoking.
Author:	Schweiger, Thomas\|Kollmann, Dagmar\|Nikolowsky, Christoph\|Traxler, Denise\|Guenova, Emmanuella\|Lang, Gyorgy\|Birner, Peter\|Klepetko, Walter\|Ankersmit, Hendrik Jan\|Hoetzenecker, Konrad
PMID:	24321995

257.
Journal:	Biochem Biophys Res Commun. 2014 Jan 17;443(3):1008-13.
Title:	N-(2-Mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant.
Author:	Yum, Soohwan\|Park, Huijeong\|Hong, Sungchae\|Jeong, Seongkeun\|Kim, Wooseong\|Jung, Yunjin
PMID:	24361888

258.
Journal:	Pathol Oncol Res. 2014 Jul;20(3):603-10.
Title:	HIF-1alpha expression correlates with cellular apoptosis, angiogenesis and clinical prognosis in rectal carcinoma.
Author:	Feng, Liu\|Tao, Lin\|Dawei, He\|Xuliang, Li\|Xiaodong, Luo
PMID:	24374863

259.
Journal:	Int J Cancer. 2014 Jul 15;135(2):295-307.
Title:	Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts.
Author:	Miyazaki, Shinichiro\|Kikuchi, Hirotoshi\|Iino, Ichirota\|Uehara, Takashi\|Setoguchi, Tomohiko\|Fujita, Takeshi\|Hiramatsu, Yoshihiro\|Ohta, Manabu\|Kamiya, Kinji\|Kitagawa, Kyoko\|Kitagawa, Masatoshi\|Baba, Satoshi\|Konno, Hiroyuki
PMID:	24375080

260.
Journal:	J Am Soc Nephrol. 2014 Mar;25(3):488-500.
Title:	Delayed administration of a single dose of lithium promotes recovery from AKI.
Author:	Bao, Hui\|Ge, Yan\|Wang, Zhen\|Zhuang, Shougang\|Dworkin, Lance\|Peng, Ai\|Gong, Rujun
PMID:	24408869

261.
Journal:	Br J Cancer. 2014 Feb 18;110(4):935-45.
Title:	Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells.
Author:	To, S K Y\|Zeng, W-J\|Zeng, J-Z\|Wong, A S T
PMID:	24423919

262.
Journal:	Front Oncol. 2014 Feb 4;4:10.
Title:	Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer.
Author:	Kuiper, Caroline\|Dachs, Gabi U\|Munn, Delwyn\|Currie, Margaret J\|Robinson, Bridget A\|Pearson, John F\|Vissers, Margreet C M
PMID:	24551593

263.
Journal:	J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9.
Title:	Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Author:	Morimoto, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Murakami, Takashi\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	24612059

264.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):769-81.
Title:	Temsirolimus and chloroquine cooperatively exhibit a potent antitumor effect against colorectal cancer cells.
Author:	Kaneko, Manabu\|Nozawa, Hiroaki\|Hiyoshi, Masaya\|Tada, Noriko\|Murono, Koji\|Nirei, Takako\|Emoto, Shigenobu\|Kishikawa, Junko\|Iida, Yuuki\|Sunami, Eiji\|Tsuno, Nelson H\|Kitayama, Joji\|Takahashi, Koki\|Watanabe, Toshiaki
PMID:	24619662

265.
Journal:	BMC Genomics. 2014 Mar 13;15:190.
Title:	Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author:	Castle, John C\|Loewer, Martin\|Boegel, Sebastian\|de Graaf, Jos\|Bender, Christian\|Tadmor, Arbel D\|Boisguerin, Valesca\|Bukur, Thomas\|Sorn, Patrick\|Paret, Claudia\|Diken, Mustafa\|Kreiter, Sebastian\|Tureci, Ozlem\|Sahin, Ugur
PMID:	24621249

266.
Journal:	Mol Cancer. 2014 Mar 14;13:58.
Title:	Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer.
Author:	Romain, Benoit\|Hachet-Haas, Muriel\|Rohr, Serge\|Brigand, Cecile\|Galzi, Jean-Luc\|Gaub, Marie-Pierre\|Pencreach, Erwan\|Guenot, Dominique
PMID:	24629239

267.
Journal:	Cancer Med. 2014 Jun;3(3):472-84.
Title:	15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1alpha expression in human colon cancer cells.
Author:	Wu, Yuanqing\|Mao, Fei\|Zuo, Xiangsheng\|Moussalli, Micheline J\|Elias, Elias\|Xu, Weiguo\|Shureiqi, Imad
PMID:	24634093

268.
Journal:	Anticancer Res. 2014 Apr;34(4):1793-800.
Title:	COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-alpha.
Author:	Bocca, Claudia\|Bozzo, Francesca\|Miglietta, Antonella
PMID:	24692712

269.
Journal:	BMC Cancer. 2014 Apr 4;14:241.
Title:	P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer.
Author:	Sim, Sung Hoon\|Kang, Mi-Hyun\|Kim, Yu Jung\|Lee, Keun-Wook\|Kim, Duck-Woo\|Kang, Sung-Bum\|Eom, Keun-Yong\|Kim, Jae-Sung\|Lee, Hye Seung\|Kim, Jee Hyun
PMID:	24708484

270.
Journal:	Virchows Arch. 2014 Jun;464(6):645-54.
Title:	Prognostic value of c-FLIPL/s, HIF-1alpha, and NF-kappabeta in stage II and III rectal cancer.
Author:	Novell, Anna\|Martinez-Alonso, Montserrat\|Mira, Moises\|Tarragona, Jordi\|Salud, Antonieta\|Matias-Guiu, Xavier
PMID:	24711168

271.
Journal:	Int J Oncol. 2014 Jun;44(6):2077-84.
Title:	HIF-1alpha activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Author:	Nishimoto, Arata\|Kugimiya, Naruji\|Hosoyama, Tohru\|Enoki, Tadahiko\|Li, Tao-Sheng\|Hamano, Kimikazu
PMID:	24718784

272.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Apr;17(4):388-92.
Title:	[Correlation and clinical significance of expressions of HIF-1alpha and Sema4D in colorectal carcinoma tissues].
Author:	Mu, Linjun\|Wang, Jinshen\|Guo, Xiaobo\|Zheng, Sheng\|Shan, Keshu\|Jing, Changqing\|Li, Leping
PMID:	24760652

273.
Journal:	PLoS One. 2014 May 7;9(5):e96755.
Title:	The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.
Author:	Iovine, Barbara\|Oliviero, Giorgia\|Garofalo, Mariangela\|Orefice, Maria\|Nocella, Francesca\|Borbone, Nicola\|Piccialli, Vincenzo\|Centore, Roberto\|Mazzone, Massimiliano\|Piccialli, Gennaro\|Bevilacqua, Maria Assunta
PMID:	24804733

274.
Journal:	Mol Cancer Res. 2014 Aug;12(8):1112-27.
Title:	Prognostic potential of DNA methylation and transcript levels of HIF1A and EPAS1 in colorectal cancer.
Author:	Rawluszko-Wieczorek, Agnieszka Anna\|Horbacka, Karolina\|Krokowicz, Piotr\|Misztal, Matthew\|Jagodzinski, Pawel Piotr
PMID:	24825851

275.
Journal:	Biochem Cell Biol. 2014 Jun;92(3):206-18.
Title:	Targeting angiogenic pathway for chemoprevention of experimental colon cancer using C-phycocyanin as cyclooxygenase-2 inhibitor.
Author:	Saini, Manpreet Kaur\|Sanyal, Sankar Nath
PMID:	24861078

276.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15;307(2):G187-95.
Title:	Activation of HIF-1alpha does not increase intestinal tumorigenesis.
Author:	Xue, Xiang\|Ramakrishnan, Sadeesh K\|Shah, Yatrik M
PMID:	24875099

277.
Journal:	PLoS One. 2014 Jun 5;9(6):e98882.
Title:	HIF-1alpha inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-glycoprotein.
Author:	Chen, Jianfang\|Ding, Zhenyu\|Peng, Yonghai\|Pan, Feng\|Li, Jianjun\|Zou, Lan\|Zhang, Yanling\|Liang, Houjie
PMID:	24901645

278.
Journal:	PLoS One. 2014 Jun 16;9(6):e99143.
Title:	CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.
Author:	Lopez-Sanchez, Laura M\|Jimenez, Carla\|Valverde, Araceli\|Hernandez, Vanessa\|Penarando, Jon\|Martinez, Antonio\|Lopez-Pedrera, Chary\|Munoz-Castaneda, Juan R\|De la Haba-Rodriguez, Juan R\|Aranda, Enrique\|Rodriguez-Ariza, Antonio
PMID:	24932611

279.
Journal:	Asian Pac J Cancer Prev. 2014;15(11):4637-42.
Title:	Genetic variations in the HIF1A gene modulate response to adjuvant chemotherapy after surgery in patients with colorectal cancer.
Author:	Zhang, Yi\|Wang, Peng\|Zhou, Xing-Chun\|Bao, Guo-Qiang\|Lyu, Zhuo-Ming\|Liu, Xiao-Nan\|Wan, Shao-Gui\|He, Xian-Li\|Huang, Qi-Chao
PMID:	24969897

280.
Journal:	Biochim Biophys Acta. 2014 Nov;1843(11):2471-80.
Title:	Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo.
Author:	Westwood, David A\|Patel, Oneel\|Baldwin, Graham S
PMID:	24998603

281.
Journal:	Oncol Rep. 2014 Dec;32(6):2493-500.
Title:	Upregulation of stromal cell-derived factor 1alpha expression is associated with the resistance to neoadjuvant chemoradiotherapy of locally advanced rectal cancer: angiogenic markers of neoadjuvant chemoradiation.
Author:	Kim, Han Jo\|Bae, Sang Byung\|Jeong, Dongjun\|Kim, Eun Seog\|Kim, Chang-Nam\|Park, Dong-Guk\|Ahn, Tae Sung\|Cho, Sung Woo\|Shin, Eung Jin\|Lee, Moon Soo\|Baek, Moo Jun
PMID:	25241658

282.
Journal:	Chin Med J (Engl). 2014;127(20):3568-75.
Title:	Hypoxia-inducible factor-1alpha and semaphorin4D genes involved with tumor-associated macrophage-induced metastatic behavior and clinical significance in colon cancer.
Author:	Mu, Linjun\|Wang, Jinshen\|Chen, Yuezhi\|Li, Leping\|Guo, Xiaobo\|Zheng, Sheng\|Jing, Changqing
PMID:	25316231

283.
Journal:	World J Gastroenterol. 2014 Oct 14;20(38):13705-17.
Title:	Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells.
Author:	Minchenko, Oleksandr H\|Tsuchihara, Katsuya\|Minchenko, Dmytro O\|Bikfalvi, Andreas\|Esumi, Hiroyasu
PMID:	25320508

284.
Journal:	J Med Chem. 2014 Nov 26;57(22):9522-38.
Title:	Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1alpha/malate dehydrogenase 2 inhibitors.
Author:	Naik, Ravi\|Won, Misun\|Ban, Hyun Seung\|Bhattarai, Deepak\|Xu, Xuezhen\|Eo, Yumi\|Hong, Ye Seul\|Singh, Sarbjit\|Choi, Yongseok\|Ahn, Hee-Chul\|Lee, Kyeong
PMID:	25356789

285.
Journal:	PLoS One. 2014 Nov 14;9(11):e112580.
Title:	Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling.
Author:	Santoyo-Ramos, Paula\|Likhatcheva, Maria\|Garcia-Zepeda, Eduardo A\|Castaneda-Patlan, M Cristina\|Robles-Flores, Martha
PMID:	25396735

286.
Journal:	PLoS One. 2014 Nov 18;9(11):e113513.
Title:	Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.
Author:	Haja Mohideen, Asan M S\|Hyde, Angela\|Squires, Jessica\|Wang, Jing\|Dicks, Elizabeth\|Younghusband, Ban\|Parfrey, Patrick\|Green, Roger\|Savas, Sevtap
PMID:	25405996

287.
Journal:	J Nucl Med. 2014 Dec;55(12):2038-44.
Title:	Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.
Author:	Iwamoto, Masayoshi\|Kawada, Kenji\|Nakamoto, Yuji\|Itatani, Yoshiro\|Inamoto, Susumu\|Toda, Kosuke\|Kimura, Hiroyuki\|Sasazuki, Takehiko\|Shirasawa, Senji\|Okuyama, Hiroaki\|Inoue, Masahiro\|Hasegawa, Suguru\|Togashi, Kaori\|Sakai, Yoshiharu
PMID:	25453050

288.
Journal:	Neuropathol Appl Neurobiol. 2015 Feb;41(2):e41-55.
Title:	Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases.
Author:	Berghoff, Anna S\|Ilhan-Mutlu, Aysegul\|Dinhof, Carina\|Magerle, Manuel\|Hackl, Monika\|Widhalm, Georg\|Hainfellner, Johannes A\|Dieckmann, Karin\|Pichler, Josef\|Hutterer, Markus\|Melchardt, Thomas\|Bartsch, Rupert\|Zielinski, Christoph C\|Birner, Peter\|Preusser, Mat
PMID:	25256708

289.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):613-27.
Title:	Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway.
Author:	Xu, Wei\|Wang, Ziwei\|Zhang, Wei\|Qian, Kun\|Li, Hui\|Kong, Dequan\|Li, Yuqiang\|Tang, Yucheng
PMID:	25305448

290.
Journal:	Histopathology. 2015 Jun;66(7):982-90.
Title:	Tumour budding is associated with hypoxia at the advancing front of colorectal cancer.
Author:	Righi, Alberto\|Sarotto, Ivana\|Casorzo, Laura\|Cavalchini, Silvia\|Frangipane, Elena\|Risio, Mauro
PMID:	25381897

291.
Journal:	Int J Oncol. 2015 Feb;46(2):750-6.
Title:	Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1alpha/miR-210/Bcl-2 pathway in colon cancer cells.
Author:	Sun, Yong\|Xing, Xing\|Liu, Qi\|Wang, Zheng\|Xin, Yuhu\|Zhang, Ping\|Hu, Chaosu\|Liu, Yong
PMID:	25385144

292.
Journal:	Med Oncol. 2015 Jan;32(1):394.
Title:	Hypoxia-inducible factor 1-alpha up-regulates the expression of phospholipase D2 in colon cancer cells under hypoxic conditions.
Author:	Liu, Maoxi\|Du, Kunli\|Fu, Zhongxue\|Zhang, Shouru\|Wu, Xingye
PMID:	25432699

293.
Journal:	Eur J Pharmacol. 2015 Jan 15;747:114-22.
Title:	Lipophilic modification enhances anti-colitic properties of rosmarinic acid by potentiating its HIF-prolyl hydroxylases inhibitory activity.
Author:	Jeong, Seongkeun\|Park, Huijeong\|Hong, Sungchae\|Yum, Soohwan\|Kim, Wooseong\|Jung, Yunjin
PMID:	25483211

294.
Journal:	Am J Physiol Cell Physiol. 2015 Mar 1;308(5):C385-96.
Title:	RORalpha inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis.
Author:	Xiao, Lei\|Wang, Jing\|Li, Jiao\|Chen, Xiongwei\|Xu, Pengfei\|Sun, Suozhu\|He, Dacheng\|Cong, Yusheng\|Zhai, Yonggong
PMID:	25500738

295.
Journal:	Steroids. 2015 Mar;95:1-6.
Title:	Non-genomic effects of the NR4A1/Nur77/TR3/NGFIB orphan nuclear receptor.
Author:	Pawlak, Alicja\|Strzadala, Leon\|Kalas, Wojciech
PMID:	25555471

296.
Journal:	Cancer Biol Ther. 2015;16(2):244-52.
Title:	Factor inhibiting HIF1alpha (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1alpha pathway.
Author:	Chen, Tao\|Ren, Zhong\|Ye, Le-Chi\|Zhou, Ping-Hong\|Xu, Jian-Min\|Shi, Qiang\|Yao, Li-Qing\|Zhong, Yun-Shi
PMID:	25602156

297.
Journal:	Oncotarget. 2015 Feb 10;6(4):1920-41.
Title:	Hypoxia induces a lipogenic cancer cell phenotype via HIF1alpha-dependent and -independent pathways.
Author:	Valli, Alessandro\|Rodriguez, Miguel\|Moutsianas, Loukas\|Fischer, Roman\|Fedele, Vita\|Huang, Hong-Lei\|Van Stiphout, Ruud\|Jones, Dylan\|Mccarthy, Michael\|Vinaxia, Maria\|Igarashi, Kaori\|Sato, Maya\|Soga, Tomoyoshi\|Buffa, Francesca\|Mccullagh, James\|Yanes, Oscar\|H
PMID:	25605240

298.
Journal:	Evid Based Complement Alternat Med. 2015;2015:454279.
Title:	Pien Tze Huang Inhibits Hypoxia-Induced Angiogenesis via HIF-1 alpha /VEGF-A Pathway in Colorectal Cancer.
Author:	Chen, Hongwei\|Feng, Jianyu\|Zhang, Yuchen\|Shen, Aling\|Chen, Youqin\|Lin, Jiumao\|Lin, Wei\|Sferra, Thomas J\|Peng, Jun
PMID:	25649293

299.
Journal:	J Med Chem. 2015 Mar 12;58(5):2452-64.
Title:	Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.
Author:	Ai, Yong\|Kang, Fenghua\|Huang, Zhangjian\|Xue, Xiaowen\|Lai, Yisheng\|Peng, Sixun\|Tian, Jide\|Zhang, Yihua
PMID:	25675144

300.
Journal:	Oncotarget. 2015 Mar 30;6(9):6776-93.
Title:	Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells.
Author:	Kopecka, Joanna\|Campia, Ivana\|Jacobs, Andrea\|Frei, Andreas P\|Ghigo, Dario\|Wollscheid, Bernd\|Riganti, Chiara
PMID:	25686827

301.
Journal:	Pharmacol Res Perspect. 2015 Feb;3(1):e00083.
Title:	Cellular density-dependent down-regulation of EP4 prostanoid receptors via the up-regulation of hypoxia-inducible factor-1alpha in HCA-7 human colon cancer cells.
Author:	Otake, Sho\|Yoshida, Kenji\|Seira, Naofumi\|Sanchez, Christopher M\|Regan, John W\|Fujino, Hiromichi\|Murayama, Toshihiko
PMID:	25692008

302.
Journal:	World J Gastroenterol. 2015 Feb 21;21(7):2191-8.
Title:	Semaphorin 4D and hypoxia-inducible factor-1alpha overexpression is related to prognosis in colorectal carcinoma.
Author:	Wang, Jin-Shen\|Jing, Chang-Qing\|Shan, Ke-Shu\|Chen, Yue-Zhi\|Guo, Xiao-Bo\|Cao, Zhi-Xin\|Mu, Lin-Jun\|Peng, Li-Pan\|Zhou, Ming-Liang\|Li, Le-Ping
PMID:	25717256

303.
Journal:	Oncotarget. 2015 Feb 28;6(6):4406-17.
Title:	HIF-2alpha mediates hypoxia-induced LIF expression in human colorectal cancer cells.
Author:	Wu, Lihua\|Yu, Haiyang\|Zhao, Yuhan\|Zhang, Cen\|Wang, Jiabei\|Yue, Xuetian\|Yang, Qifeng\|Hu, Wenwei
PMID:	25726527

304.
Journal:	Fitoterapia. 2015 Jun;103:55-62.
Title:	HIF-prolyl hydroxylase is a potential molecular target for esculetin-mediated anti-colitic effects.
Author:	Yum, Soohwan\|Jeong, Seongkeun\|Lee, Sunyoung\|Kim, Wooseong\|Nam, Joon\|Jung, Yunjin
PMID:	25797536

305.
Journal:	J Med Invest. 2015;62(1-2):75-9.
Title:	Chronic exposure of VEGF inhibitors promotes the malignant phenotype of colorectal cancer cells.
Author:	Tomida, Chisato\|Yamagishi, Naoko\|Aibara, Kana\|Yano, Chiaki\|Uchida, Takayuki\|Abe, Tomoki\|Ohno, Ayako\|Hirasaka, Katsuya\|Nikawa, Takeshi\|Teshima-Kondo, Shigetada
PMID:	25817288

306.
Journal:	Asian Pac J Cancer Prev. 2015;16(6):2569-74.
Title:	Cobalt chloride induces necroptosis in human colon cancer HT-29 cells.
Author:	Wang, Hai-Yu\|Zhang, Bo
PMID:	25824798

307.
Journal:	Pharm Res. 2015 Sep;32(9):3029-43.
Title:	Anti-angiogenic Effects of Bumetanide Revealed by DCE-MRI with a Biodegradable Macromolecular Contrast Agent in a Colon Cancer Model.
Author:	Malamas, Anthony S\|Jin, Erlei\|Zhang, Qi\|Haaga, John\|Lu, Zheng-Rong
PMID:	25840948

308.
Journal:	Oncotarget. 2015 Jun 30;6(18):16198-214.
Title:	Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor.
Author:	Wei, Libin\|Zhou, Yuxin\|Yao, Jing\|Qiao, Chen\|Ni, Ting\|Guo, Ruichen\|Guo, Qinglong\|Lu, Na
PMID:	25938544

309.
Journal:	Oncotarget. 2015 Aug 21;6(24):20288-301.
Title:	Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IkappaB.
Author:	Muller-Edenborn, Kamila\|Leger, Karolin\|Glaus Garzon, Jesus F\|Oertli, Carole\|Mirsaidi, Ali\|Richards, Peter J\|Rehrauer, Hubert\|Spielmann, Patrick\|Hoogewijs, David\|Borsig, Lubor\|Hottiger, Michael O\|Wenger, Roland H
PMID:	25978030

310.
Journal:	Cancer Lett. 2015 Aug 10;364(2):156-64.
Title:	The BH3-mimetic obatoclax reduces HIF-1alpha levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil.
Author:	Gariboldi, Marzia B\|Taiana, Elisa\|Bonzi, Maria Chiara\|Craparotta, Ilaria\|Giovannardi, Stefano\|Mancini, Monica\|Monti, Elena
PMID:	25979228

311.
Journal:	Oncotarget. 2015 Aug 21;6(24):20723-39.
Title:	Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP).
Author:	Evensen, Nikki A\|Li, Yiyi\|Kuscu, Cem\|Liu, Jingxuan\|Cathcart, Jillian\|Banach, Anna\|Zhang, Qian\|Li, Ellen\|Joshi, Sonia\|Yang, Jie\|Denoya, Paula I\|Pastorekova, Silvia\|Zucker, Stanley\|Shroyer, Kenneth R\|Cao, Jian
PMID:	26009875

312.
Journal:	Am J Cancer Res. 2015 Feb 15;5(3):1047-61. eCollection 2015.
Title:	Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.
Author:	Xie, Jing\|Gao, Hui\|Peng, Jianjun\|Han, Yantao\|Chen, Xuehong\|Jiang, Qixiao\|Wang, Chunbo
PMID:	26045985

313.
Journal:	Onco Targets Ther. 2015 May 26;8:1229-37.
Title:	Positive feedback between oncogenic KRAS and HIF-1alpha confers drug resistance in colorectal cancer.
Author:	Wang, Yanzhao\|Lei, Fuming\|Rong, Wanshui\|Zeng, Qingmin\|Sun, Wenbing
PMID:	26060408

314.
Journal:	Diagn Pathol. 2015 Jun 12;10:65.
Title:	A critical role of mir-199a in the cell biological behaviors of colorectal cancer.
Author:	Ye, Hua\|Pang, Liping\|Wu, Qiong\|Zhu, Yuzhen\|Guo, Cancan\|Deng, Ying\|Zheng, Xuebao
PMID:	26065676

315.
Journal:	Biomed Res Int. 2015;2015:523930.
Title:	Nampt/PBEF/visfatin upregulation in colorectal tumors, mirrored in normal tissue and whole blood of colorectal cancer patients, is associated with metastasis, hypoxia, IL1beta, and anemia.
Author:	Neubauer, Katarzyna\|Misa, Iwona Bednarz\|Diakowska, Dorota\|Kapturkiewicz, Bartosz\|Gamian, Andrzej\|Krzystek-Korpacka, Malgorzata
PMID:	26075243

316.
Journal:	Oncotarget. 2015 Jul 30;6(21):18590-601.
Title:	Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis.
Author:	Huang, Yen-Chia\|Huang, Fang-I\|Mehndiratta, Samir\|Lai, Ssu-Chia\|Liou, Jing-Ping\|Yang, Chia-Ron
PMID:	26087180

317.
Journal:	Mol Med Rep. 2015 Sep;12(3):4508-4513.
Title:	Triptolide suppresses proliferation, hypoxia-inducible factor-1alpha and c-Myc expression in pancreatic cancer cells.
Author:	Ding, Xiaoling\|Zhou, Xiaorong\|Jiang, Bo\|Zhao, Qun\|Zhou, Guoxiong
PMID:	26094625

318.
Journal:	Cancer Lett. 2015 Sep 28;366(1):11-8.
Title:	Hypoxia inducible factor-1alpha: Its role in colorectal carcinogenesis and metastasis.
Author:	Nagaraju, Ganji Purnachandra\|Bramhachari, Pallaval Veera\|Raghu, Godi\|El-Rayes, Bassel F
PMID:	26116902

319.
Journal:	Int J Clin Exp Med. 2015 Apr 15;8(4):5075-84. eCollection 2015.
Title:	Microarray analysis of anti-cancer effects of docosahexaenoic acid on human colon cancer model in nude mice.
Author:	Zou, Shitao\|Meng, Xingjun\|Meng, You\|Liu, Jin\|Liu, Biao\|Zhang, Shuyu\|Ding, Weiqun\|Wu, Jinchang\|Zhou, Jundong
PMID:	26131080

320.
Journal:	Dis Model Mech. 2015 Sep;8(9):1093-103.
Title:	HIF1alpha deficiency reduces inflammation in a mouse model of proximal colon cancer.
Author:	Mladenova, Dessislava N\|Dahlstrom, Jane E\|Tran, Phuong N\|Benthani, Fahad\|Bean, Elaine G\|Ng, Irvin\|Pangon, Laurent\|Currey, Nicola\|Kohonen-Corish, Maija R J
PMID:	26183215

321.
Journal:	Oncotarget. 2015 Sep 15;6(27):24092-104.
Title:	eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer.
Author:	Chao, Min-Wu\|Wang, Li-Ting\|Lai, Chin-Yu\|Yang, Xiao-Ming\|Cheng, Ya-Wen\|Lee, Kuo-Hsiung\|Pan, Shiow-Lin\|Teng, Che-Ming
PMID:	26204490

322.
Journal:	J BUON. 2015 May-Jun;20(3):680-9.
Title:	HIF-1alpha in colorectal carcinoma: review of the literature.
Author:	Ioannou, Maria\|Paraskeva, Efrosyni\|Baxevanidou, Korina\|Simos, George\|Papamichali, Roidoula\|Papacharalambous, Constantina\|Samara, Maria\|Koukoulis, George
PMID:	26214618

323.
Journal:	Onco Targets Ther. 2015 Jul 29;8:1941-8.
Title:	Hypoxia-inducible factor-1alpha induces multidrug resistance protein in colon cancer.
Author:	Lv, Yingqian\|Zhao, Shan\|Han, Jinzhu\|Zheng, Likang\|Yang, Zixin\|Zhao, Li
PMID:	26251616

324.
Journal:	Asian Pac J Cancer Prev. 2015;16(14):6149-54.
Title:	Predictive Significance of VEGF and HIF-1alpha Expression in Patients with Metastatic Colorectal Cancer Receiving Chemotherapy Combinations with Bevacizumab.
Author:	Berk, Veli\|Deniz, Kemal\|Bozkurt, Oktay\|Ozaslan, Ersin\|Karaca, Halit\|Inanc, Mevlude\|Duran, Ayse Ocak\|Ozkan, Metin
PMID:	26320510

325.
Journal:	Int J Clin Exp Pathol. 2015 Jul 1;8(7):7913-20. eCollection 2015.
Title:	Anti-angiogenic and anti-proliferative effects of inhibition of HIF-1alpha by p-HIF-1alpha RNAi in colorectal cancer.
Author:	Qiu, Yan-Yan\|Hu, Song-Jiao\|Bao, Yi-Jie\|Liang, Bo\|Yan, Cui-Na\|Shi, Xiao-Jing\|Yu, Hui\|Zou, Yu\|Tang, Li-Rui\|Tang, Qing-Feng\|Feng, Wen\|Yin, Pei-Hao
PMID:	26339356

326.
Journal:	PLoS One. 2015 Sep 9;10(9):e0137513.
Title:	HIF1alpha-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5.
Author:	No, Yi Ran\|Lee, Sei-Jung\|Kumar, Ajay\|Yun, C Chris
PMID:	26352431

327.
Journal:	World J Gastroenterol. 2015 Sep 14;21(34):9887-99.
Title:	Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancer.
Author:	Kim, Jung Ho\|Hwang, You-Jin\|Han, Sang Hoon\|Lee, Young Eun\|Kim, Saerom\|Kim, Yoon Jae\|Cho, Jae Hee\|Kwon, Kwang An\|Kim, Ju Hyun\|Kim, Se-Hee
PMID:	26379394

328.
Journal:	Oncotarget. 2015 Oct 27;6(33):34732-44.
Title:	Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment.
Author:	Sun, Xiaorong\|Ackerstaff, Ellen\|He, Fuqiu\|Xing, Ligang\|Hsiao, Hung Tsung\|Koutcher, Jason A\|Ling, C Clifton\|Li, Gloria C
PMID:	26416246

329.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 Jul;46(4):537-41.
Title:	[Effect of HIF-1alpha Gene Silence on Biological Characteristics of Human Colon Cancer Cells SW480].
Author:	Wang, Qiang\|Hao, Lang-song\|Shi, Jia\|Huang, Jian
PMID:	26480654

330.
Journal:	Int J Oncol. 2015 Dec;47(6):2226-32.
Title:	Sulforaphane inhibits hypoxia-induced HIF-1alpha and VEGF expression and migration of human colon cancer cells.
Author:	Kim, Dong Hwan\|Sung, Bokyung\|Kang, Yong Jung\|Hwang, Seong Yeon\|Kim, Min Jeong\|Yoon, Jeong-Hyun\|Im, Eunok\|Kim, Nam Deuk
PMID:	26498863

331.
Journal:	Oncol Rep. 2015 Dec;34(6):3203-11.
Title:	Antiproliferation effect of evodiamine in human colon cancer cells is associated with IGF-1/HIF-1alpha downregulation.
Author:	Huang, Jun\|Chen, Zhen-Hua\|Ren, Chun-Mei\|Wang, Dong-Xu\|Yuan, Shuang-Xue\|Wu, Qiu-Xiang\|Chen, Qian-Zhao\|Zeng, Yu-Hua\|Shao, Ying\|Li, Yang\|Wu, Ke\|Yu, Yu\|Sun, Wen-Juan\|He, Bai-Cheng
PMID:	26503233

332.
Journal:	Mar Drugs. 2015 Nov 19;13(11):6962-76.
Title:	Salternamide A Suppresses Hypoxia-Induced Accumulation of HIF-1alpha and Induces Apoptosis in Human Colorectal Cancer Cells.
Author:	Bach, Duc-Hiep\|Kim, Seong-Hwan\|Hong, Ji-Young\|Park, Hyen Joo\|Oh, Dong-Chan\|Lee, Sang Kook
PMID:	26610526

333.
Journal:	World J Gastroenterol. 2015 Dec 28;21(48):13447-56.
Title:	Hypoxia-inducible factor-1 modulates upregulation of mutT homolog-1 in colorectal cancer.
Author:	Qiu, Yuan\|Zheng, Hong\|Sun, Li-Hua\|Peng, Ke\|Xiao, Wei-Dong\|Yang, Hua
PMID:	26730155

334.
Journal:	Am J Cancer Res. 2015 Oct 15;5(11):3286-300. eCollection 2015.
Title:	Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer.
Author:	Park, Young-Lan\|Myung, Eun\|Park, Sun-Young\|Kim, Nuri\|Oak, Chan-Young\|Myung, Dae-Seong\|Cho, Sung-Bum\|Lee, Wan-Sik\|Kweon, Sun-Seog\|Kim, Hyun-Soo\|Joo, Young-Eun
PMID:	26807311

335.
Journal:	Ann Surg. 2016 Jan;263(1):138-45.
Title:	Glucose Transporter 1 (SLC2A1) and Vascular Endothelial Growth Factor A (VEGFA) Predict Survival After Resection of Colorectal Cancer Liver Metastasis.
Author:	Goos, Jeroen A C M\|de Cuba, Erienne M V\|Coupe, Veerle M H\|Diosdado, Begona\|Delis-Van Diemen, Pien M\|Karga, Cemile\|Belien, Jeroen A M\|Menke-Van der Houven van Oordt, C Willemien\|Geldof, Albert A\|Meijer, Gerrit A\|Hoekstra, Otto S\|Fijneman, Remond J A
PMID:	25563886

336.
Journal:	Tumour Biol. 2016 Jan;37(1):425-35.
Title:	E-cadherin increasing multidrug resistance protein 1 via hypoxia-inducible factor-1alpha contributes to multicellular resistance in colorectal cancer.
Author:	Liang, Xi\|Xu, Xueqing\|Wang, Fengchao\|Li, Ni\|He, Jianming
PMID:	26219897

337.
Journal:	Eur J Cancer Prev. 2016 Nov;25(6):481-9.
Title:	Anti-Warburg effect of rosmarinic acid via miR-155 in colorectal carcinoma cells.
Author:	Xu, Yichun\|Han, Shuai\|Lei, Kesheng\|Chang, Xinnan\|Wang, Ke\|Li, Zhou\|Liu, Jianwen
PMID:	26340059

338.
Journal:	Oncotarget. 2016 Jan 12;7(2):2123-34.
Title:	A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9.
Author:	Goos, Jeroen A C M\|Coupe, Veerle M H\|van de Wiel, Mark A\|Diosdado, Begona\|Delis-Van Diemen, Pien M\|Hiemstra, Annemieke C\|de Cuba, Erienne M V\|Belien, Jeroen A M\|Menke-van der Houven van Oordt, C Willemien\|Geldof, Albert A\|Meijer, Gerrit A\|Hoekstra, Otto S
PMID:	26497206

339.
Journal:	Annu Rev Physiol. 2016;78:301-25.
Title:	Role of Intestinal HIF-2alpha in Health and Disease.
Author:	Ramakrishnan, Sadeesh K\|Shah, Yatrik M
PMID:	26667076

340.
Journal:	Oncol Rep. 2016 Feb;35(2):985-91.
Title:	Study on the inhibition of hyperthermic CO(2) pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism.
Author:	Zhao, Jiaying\|Cai, Yuankun\|Yin, Chenqing\|Lv, You\|Wei, Wanmin\|Wang, Xin\|Hao, Zong\|Shen, Chenxia\|Wang, Huipeng\|Chen, Jun
PMID:	26718327

341.
Journal:	Ann Surg Oncol. 2016 May;23(5):1601-8.
Title:	Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer.
Author:	de Cuba, E M V\|de Hingh, I H J T\|Sluiter, N R\|Kwakman, R\|Coupe, V M H\|Belien, J A M\|Verwaal, V J\|Meijerink, W J H J\|Delis-van Diemen, P M\|Bonjer, H J\|Meijer, G A\|Te Velde, E A
PMID:	26727921

342.
Journal:	Mol Imaging Biol. 2016 Aug;18(4):606-16.
Title:	Baseline [(18)F]FMISO muPET as a Predictive Biomarker for Response to HIF-1alpha Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model.
Author:	De Bruycker, Sven\|Vangestel, Christel\|Van den Wyngaert, Tim\|Wyffels, Leonie\|Wouters, An\|Pauwels, Patrick\|Staelens, Steven\|Stroobants, Sigrid
PMID:	26728163

343.
Journal:	Oncotarget. 2016 Feb 2;7(5):5800-14.
Title:	RPS7 inhibits colorectal cancer growth via decreasing HIF-1alpha-mediated glycolysis.
Author:	Zhang, Wen\|Tong, Duo\|Liu, Fei\|Li, Dawei\|Li, Jiajia\|Cheng, Xi\|Wang, Ziliang
PMID:	26735579

344.
Journal:	Eur J Med Chem. 2016 Feb 15;109:247-53.
Title:	Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.
Author:	Alafeefy, Ahmed M\|Ahmad, Rehan\|Abdulla, Maha\|Eldehna, Wagdy M\|Al-Tamimi, Abdul-Malek S\|Abdel-Aziz, Hatem A\|Al-Obaid, Omar\|Carta, Fabrizio\|Al-Kahtani, Abdulla A\|Supuran, Claudiu T
PMID:	26774930

345.
Journal:	PLoS One. 2016 Jan 19;11(1):e0147038.
Title:	Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1alpha.
Author:	Han, Hyeong-Jun\|Kwon, Nayoung\|Choi, Min-A\|Jung, Kyung Oh\|Piao, Juan-Yu\|Ngo, Hoang Kieu Chi\|Kim, Su-Jung\|Kim, Do-Hee\|Chung, June-Key\|Cha, Young-Nam\|Youn, Hyewon\|Choi, Bu Young\|Min, Sang-Hyun\|Surh, Young-Joon
PMID:	26784107

346.
Journal:	J Biomed Sci. 2016 Jan 28;23:18.
Title:	Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer.
Author:	Cheng, Chun-Chia\|Guan, Siao-Syun\|Yang, Hao-Jhih\|Chang, Chun-Chao\|Luo, Tsai-Yueh\|Chang, Jungshan\|Ho, Ai-Sheng
PMID:	26822586

347.
Journal:	Oncotarget. 2016 Mar 1;7(9):10578-93.
Title:	Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells.
Author:	Chang, Elizabeth T\|Parekh, Palak R\|Yang, Qingyuan\|Nguyen, Duc M\|Carrier, France
PMID:	26824423

348.
Journal:	Mol Med Rep. 2016 Mar;13(3):2583-9.
Title:	The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells.
Author:	Yang, Guanglei\|Xu, Shuqing\|Peng, Lintao\|Li, Hui\|Zhao, Yan\|Hu, Yanfang
PMID:	26846577

349.
Journal:	Int J Mol Med. 2016 Mar;37(3):734-42.
Title:	Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.
Author:	Yang, Lian\|Xiao, Ming\|Li, Xian\|Tang, Yi\|Wang, Ya-Lan
PMID:	26847718

350.
Journal:	J Exp Clin Cancer Res. 2016 Feb 9;35:29.
Title:	LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1alpha activation.
Author:	Zhang, Jingjing\|Zhu, Lingyin\|Fang, Jingyuan\|Ge, Zhizheng\|Li, Xiaobo
PMID:	26856989

351.
Journal:	Oncotarget. 2016 Mar 8;7(10):11567-79.
Title:	HIF-3alpha1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling.
Author:	Xue, Xiang\|Jungles, Kylie\|Onder, Gunseli\|Samhoun, Jalal\|Gyorffy, Balazs\|Hardiman, Karin M
PMID:	26871465

352.
Journal:	Oncotarget. 2016 Feb 16;7(7):8172-83.
Title:	Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling.
Author:	Hsu, Chia-Wen\|Huang, Ruili\|Khuc, Thai\|Shou, David\|Bullock, Joshua\|Grooby, Suzanne\|Griffin, Sue\|Zou, Chaozhong\|Little, Annette\|Astley, Holly\|Xia, Menghang
PMID:	26882567

353.
Journal:	Oncol Lett. 2016 Feb;11(2):1371-1374.
Title:	Effects of CIK on hypoxia inducible factor-1alpha and T-cell subsets on colon 26 cancer xenograft mice.
Author:	Zhang, Hongzhen\|Guo, Mingli\|Chen, Hongyao\|Zhang, Ying\|He, Li Ya
PMID:	26893745

354.
Journal:	J Magn Reson Imaging. 2016 Sep;44(3):594-600.
Title:	MRI In rectal cancer: Correlations between MRI features and molecular markers Ki-67, HIF-1alpha, and VEGF.
Author:	Meng, Xiangjiao\|Li, Huijuan\|Kong, Lingling\|Zhao, Xianguang\|Huang, Zhaoqin\|Zhao, Hanxi\|Zhu, Wanqi\|Li, Xiaolin\|Yu, Jinming\|Xing, Ligang
PMID:	26919464

355.
Journal:	Neoplasma. 2016;63(3):351-61.
Title:	Physcion 8-O-beta-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN.
Author:	Ding, Z\|Xu, F\|Tang, J\|Li, G\|Jiang, P\|Tang, Z\|Wu, H
PMID:	26925795

356.
Journal:	BMC Cancer. 2016 Mar 7;16:189.
Title:	Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
Author:	Shukla, Pradeep K\|Chaudhry, Kamaljit K\|Mir, Hina\|Gangwar, Ruchika\|Yadav, Nikki\|Manda, Bhargavi\|Meena, Avtar S\|Rao, RadhaKrishna
PMID:	26951793

357.
Journal:	Cancer Lett. 2016 Jun 28;376(1):34-42.
Title:	RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1alpha mRNA is translated.
Author:	Tanabe, Atsushi\|Tanikawa, Kenya\|Tsunetomi, Mai\|Takai, Kaori\|Ikeda, Hiroto\|Konno, Junpei\|Torigoe, Toshihiko\|Maeda, Hideki\|Kutomi, Goro\|Okita, Kenji\|Mori, Mitsuru\|Sahara, Hiroeki
PMID:	26996300

358.
Journal:	Oncol Rep. 2016 Jun;35(6):3331-40.
Title:	Effect of Recepteur d'Origine Nantais expression on chemosensitivity and tumor cell behavior in colorectal cancer.
Author:	Kim, Nuri\|Cho, Sung-Bum\|Park, Young-Lan\|Park, Sun-Young\|Myung, Eun\|Kim, Seung-Hun\|Yu, Hyung-Min\|Son, Young-Ae\|Myung, Dae-Seong\|Lee, Wan-Sik\|Joo, Young-Eun
PMID:	27035413

359.
Journal:	Oncol Lett. 2016 Apr;11(4):2725-2732.
Title:	Establishment of a colorectal cancer nude mouse visualization model of HIF-1alpha overexpression.
Author:	Li, Zhe\|Wang, Jiye\|Zhou, Tianbao\|Ye, Xiaolei
PMID:	27073543

360.
Journal:	Oncol Lett. 2016 Apr;11(4):2879-2885.
Title:	c-MET inhibition enhances the response of the colorectal cancer cells to irradiation in vitro and in vivo.
Author:	Jia, Yitao\|Dai, Guangyao\|Wang, Jinxi\|Gao, Xing\|Zhao, Zhaolong\|Duan, Zhihui\|Gu, Bin\|Yang, Weiguang\|Wu, Jianhua\|Ju, Yingchao\|Wang, Mingxia\|Li, Zhongxin
PMID:	27073569

361.
Journal:	Cancer Lett. 2016 Jul 1;376(2):293-302.
Title:	MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis.
Author:	Ma, Huabin\|Pan, Jin-Shui\|Jin, Li-Xin\|Wu, Jianfeng\|Ren, Yan-Dan\|Chen, Pengda\|Xiao, Changchun\|Han, Jiahuai
PMID:	27080303

362.
Journal:	PLoS One. 2016 Apr 28;11(4):e0154326.
Title:	Biobanking of Fresh-Frozen Human Adenocarcinomatous and Normal Colon Tissues: Which Parameters Influence RNA Quality?
Author:	Galissier, Thibaut\|Schneider, Christophe\|Nasri, Saviz\|Kanagaratnam, Lukshe\|Fichel, Caroline\|Coquelet, Christelle\|Diebold, Marie-Daniele\|Kianmanesh, Reza\|Bellon, Georges\|Dedieu, Stephane\|Marchal Bressenot, Aude\|Boulagnon-Rombi, Camille
PMID:	27124490

363.
Journal:	Anticancer Res. 2016 May;36(5):2433-40.
Title:	Increase in Gene Expression of TYMP, DPYD and HIF1A Are Associated with Response to Preoperative Chemoradiotherapy Including S-1 or UFT for Rectal Cancer.
Author:	Sadahiro, Sotaro\|Suzuki, Toshiyuki\|Tanaka, Akira\|Okada, Kazutake\|Saito, Gota\|Kamijo, Akemi\|Nagase, Hideki
PMID:	27127154

364.
Journal:	J Nat Prod. 2016 May 27;79(5):1267-75.
Title:	Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1alpha/p300 Interaction.
Author:	Goey, Andrew K L\|Chau, Cindy H\|Sissung, Tristan M\|Cook, Kristina M\|Venzon, David J\|Castro, Amaya\|Ransom, Tanya R\|Henrich, Curtis J\|McKee, Tawnya C\|McMahon, James B\|Grkovic, Tanja\|Cadelis, Melissa M\|Copp, Brent R\|Gustafson, Kirk R\|Figg, William D
PMID:	27140429

365.
Journal:	Oncotarget. 2016 Jun 14;7(24):36551-36562.
Title:	Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer.
Author:	Ma, Juan\|Mi, Chunliu\|Wang, Ke Si\|Lee, Jung Joon\|Jin, Xuejun
PMID:	27144516

366.
Journal:	Chem Biol Interact. 2016 Jun 25;253:112-24.
Title:	An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells.
Author:	Reddy, Neetinkumar D\|Shoja, M H\|Biswas, Subhankar\|Nayak, Pawan G\|Kumar, Nitesh\|Rao, C Mallikarjuna
PMID:	27163855

367.
Journal:	Int J Oncol. 2016 Jul;49(1):276-84.
Title:	Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma.
Author:	Harada, Koji\|Ferdous, Tarannum\|Harada, Toyoko\|Ueyama, Yoshiya
PMID:	27210058

368.
Journal:	Biochimie. 2016 Aug;127:196-204.
Title:	l-carnosine dipeptide overcomes acquired resistance to 5-fluorouracil in HT29 human colon cancer cells via downregulation of HIF1-alpha and induction of apoptosis.
Author:	Iovine, Barbara\|Guardia, Francesca\|Irace, Carlo\|Bevilacqua, Maria Assunta
PMID:	27234614

369.
Journal:	Mol Pharm. 2016 Jul 5;13(7):2497-506.
Title:	Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles.
Author:	Malamas, Anthony S\|Jin, Erlei\|Gujrati, Maneesh\|Lu, Zheng-Rong
PMID:	27264671

370.
Journal:	Int J Oncol. 2016 Aug;49(2):639-45.
Title:	Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Author:	Esposito, Giuseppe\|Gigli, Stefano\|Seguella, Luisa\|Nobile, Nicola\|D'Alessandro, Alessandra\|Pesce, Marcella\|Capoccia, Elena\|Steardo, Luca\|Cirillo, Carla\|Cuomo, Rosario\|Sarnelli, Giovanni
PMID:	27279570

371.
Journal:	Cell Rep. 2016 Jun 28;16(1):37-47.
Title:	The TIP60 Complex Is a Conserved Coactivator of HIF1A.
Author:	Perez-Perri, Joel I\|Dengler, Veronica L\|Audetat, K Audrey\|Pandey, Ahwan\|Bonner, Elizabeth A\|Urh, Marjeta\|Mendez, Jacqui\|Daniels, Danette L\|Wappner, Pablo\|Galbraith, Matthew D\|Espinosa, Joaquin M
PMID:	27320910

372.
Journal:	Oncotarget. 2016 Jul 19;7(29):45889-45900.
Title:	Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings.
Author:	Lu, Pei-Hua\|Chen, Min-Bin\|Ji, Chao\|Li, Wen-Ting\|Wei, Mu-Xin\|Wu, Mian-Hua
PMID:	27322552

373.
Journal:	Nat Commun. 2016 Jun 29;7:11996.
Title:	SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin.
Author:	Dai, Lei\|Cui, Xueliang\|Zhang, Xin\|Cheng, Lin\|Liu, Yi\|Yang, Yang\|Fan, Ping\|Wang, Qingnan\|Lin, Yi\|Zhang, Junfeng\|Li, Chunlei\|Mao, Ying\|Wang, Qin\|Su, Xiaolan\|Zhang, Shuang\|Peng, Yong\|Yang, Hanshuo\|Hu, Xun\|Yang, Jinliang\|Huang, Meijuan\|Xiang, Rong\|Yu, Dechao\|
PMID:	27353863

374.
Journal:	Oncotarget. 2016 Aug 2;7(31):50057-50073.
Title:	Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling.
Author:	Xiao, Bin\|Chen, Daxiang\|Luo, Shuhong\|Hao, Wenbo\|Jing, Fangyan\|Liu, Tiancai\|Wang, Suihai\|Geng, Yan\|Li, Linhai\|Xu, Weiwen\|Zhang, Yajie\|Liao, Xiaoqing\|Zuo, Daming\|Wu, Yingsong\|Li, Ming\|Ma, Qiang
PMID:	27367023

375.
Journal:	Am J Transl Res. 2016 Jun 15;8(6):2783-9. eCollection 2016.
Title:	miR-526b-3p functions as a tumor suppressor in colon cancer by regulating HIF-1alpha.
Author:	Zhang, Rui\|Zhao, Jian\|Xu, Jian\|Wang, Jian\|Jia, Jianhui
PMID:	27398161

376.
Journal:	Virchows Arch. 2016 Oct;469(4):395-404.
Title:	HIF-1alpha expression and high microvessel density are characteristic features in serrated colorectal cancer.
Author:	Tuomisto, Anne\|Garcia-Solano, Jose\|Sirnio, Paivi\|Vayrynen, Juha\|Perez-Guillermo, Miguel\|Makinen, Markus J\|Conesa-Zamora, Pablo
PMID:	27421843

377.
Journal:	Oncol Rep. 2016 Sep;36(3):1526-34.
Title:	A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Author:	Dai, Bingling\|Wang, Wenjie\|Ma, Yujiao\|Liu, Rui\|Zhang, Yanmin
PMID:	27460008

378.
Journal:	J Zhejiang Univ Sci B. 2016 Sep;17(9):672-82.
Title:	Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1alpha.
Author:	Shan, Jian-Zhen\|Xuan, Yan-Yan\|Zhang, Qi\|Huang, Jian-Jin
PMID:	27604859

379.
Journal:	PLoS One. 2016 Sep 9;11(9):e0162568.
Title:	A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration.
Author:	Ban, Hyun Seung\|Xu, Xuezhen\|Jang, Kusik\|Kim, Inhyub\|Kim, Bo-Kyung\|Lee, Kyeong\|Won, Misun
PMID:	27611801

380.
Journal:	Oncotarget. 2016 Oct 18;7(42):68749-68767.
Title:	Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
Author:	Moench, Romana\|Grimmig, Tanja\|Kannen, Vinicius\|Tripathi, Sudipta\|Faber, Marc\|Moll, Eva-Maria\|Chandraker, Anil\|Lissner, Reinhard\|Germer, Christoph-Thomas\|Waaga-Gasser, Ana Maria\|Gasser, Martin
PMID:	27626684

381.
Journal:	Oncol Rep. 2016 Nov;36(5):2951-2959.
Title:	In vitro and in vivo activities of an antitumor peptide HM-3: A special dose-efficacy relationship on an HCT116 xenograft model in nude mice.
Author:	Yassin, Sitelbanat\|Hu, Jialiang\|Xu, Hanmei\|Li, Ce\|Setrerrahmane, Sarra
PMID:	27633584

382.
Journal:	Radiat Oncol J. 2016 Sep;34(3):230-238.
Title:	Gold nanoparticles enhance anti-tumor effect of radiotherapy to hypoxic tumor.
Author:	Kim, Mi Sun\|Lee, Eun-Jung\|Kim, Jae-Won\|Chung, Ui Seok\|Koh, Won-Gun\|Keum, Ki Chang\|Koom, Woong Sub
PMID:	27730800

383.
Journal:	Oncotarget. 2016 Nov 1;7(44):72229-72241.
Title:	Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer.
Author:	Park, Young-Lan\|Park, Sun-Young\|Lee, Seung-Hyun\|Kim, Rul-Bin\|Kim, Joong-Keun\|Rew, Sung-Yoon\|Myung, Dae-Seong\|Cho, Sung-Bum\|Lee, Wan-Sik\|Kim, Hyun-Soo\|Joo, Young-Eun
PMID:	27750216

384.
Journal:	Mol Med Rep. 2016 Dec;14(6):5148-5154.
Title:	Inhibitory effects of dieckol on hypoxia-induced epithelial-mesenchymal transition of HT29 human colorectal cancer cells.
Author:	Jeong, Seung-Hyun\|Jeon, You-Jin\|Park, Sun Joo
PMID:	27779676

385.
Journal:	Oncotarget. 2016 Nov 29;7(48):78910-78917.
Title:	c-Myc is regulated by HIF-2alpha in chronic hypoxia and influences sensitivity to 5-FU in colon cancer.
Author:	Wang, Liangjing\|Xue, Meng\|Chung, Daniel C
PMID:	27793037

386.
Journal:	Hypoxia (Auckl). 2016 Apr 8;4:41-52.
Title:	Ascorbate availability affects tumor implantation-take rate and increases tumor rejection in Gulo(-/-) mice.
Author:	Campbell, Elizabeth J\|Vissers, Margreet Cm\|Dachs, Gabi U
PMID:	27800507

387.
Journal:	Biol Pharm Bull. 2016;39(11):1830-1838.
Title:	Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1alpha Accumulation.
Author:	Seo, Suho\|Seo, Kyuhwa\|Ki, Sung Hwan\|Shin, Sang Mi
PMID:	27803454

388.
Journal:	BMC Complement Altern Med. 2016 Nov 2;16(1):428.
Title:	Yi Ai Fang, a traditional Chinese herbal formula, impacts the vasculogenic mimicry formation of human colorectal cancer through HIF-1alpha and epithelial mesenchymal transition.
Author:	Hou, Fenggang\|Li, Wen\|Shi, Qi\|Li, Hongjia\|Liu, Shanshan\|Zong, Shaoqi\|Ren, Jianlin\|Chai, Jie\|Xu, Jian
PMID:	27806701

389.
Journal:	Free Radic Biol Med. 2016 Dec;101:511-523.
Title:	Sestrin2 inhibits hypoxia-inducible factor-1alpha accumulation via AMPK-mediated prolyl hydroxylase regulation.
Author:	Seo, Kyuhwa\|Seo, Suho\|Ki, Sung Hwan\|Shin, Sang Mi
PMID:	27840318

390.
Journal:	Sci Rep. 2016 Nov 21;6:37534.
Title:	Hypoxia-induced vasculogenic mimicry formation in human colorectal cancer cells: Involvement of HIF-1a, Claudin-4, and E-cadherin and Vimentin.
Author:	Li, Wen\|Zong, ShaoQi\|Shi, Qi\|Li, HongJia\|Xu, Jian\|Hou, Fenggang
PMID:	27869227

391.
Journal:	J Gen Virol. 2016 Dec;97(12):3174-3182.
Title:	Newcastle disease virus degrades HIF-1alpha through proteasomal pathways independent of VHL and p53.
Author:	Abd-Aziz, Noraini\|Stanbridge, Eric J\|Shafee, Norazizah
PMID:	27902314

392.
Journal:	Nat Commun. 2016 Dec 14;7:13593.
Title:	NQO1 inhibits proteasome-mediated degradation of HIF-1alpha.
Author:	Oh, Eun-Taex\|Kim, Jung-Whan\|Kim, Joon Mee\|Kim, Soo Jung\|Lee, Jae-Seon\|Hong, Soon-Sun\|Goodwin, Justin\|Ruthenborg, Robin J\|Jung, Myung Gu\|Lee, Hae-June\|Lee, Chul-Ho\|Park, Eun Sung\|Kim, Chulhee\|Park, Heon Joo
PMID:	27966538

393.
Journal:	Genet Mol Res. 2016 Dec 2;15(4). pii: gmr-15-04-gmr.15048936.
Title:	Hypoxia facilitates epithelial-mesenchymal transition-mediated rectal cancer progress.
Author:	Sun, L L\|Song, Z\|Li, W Z\|Tang, S Y
PMID:	27966740

394.
Journal:	Oxid Med Cell Longev. 2016;2016:1204715.
Title:	Partial Oxygen Pressure Affects the Expression of Prognostic Biomarkers HIF-1 Alpha, Ki67, and CK20 in the Microenvironment of Colorectal Cancer Tissue.
Author:	Zhang, Lirong\|Hu, Yu\|Xi, Ning\|Song, Jie\|Huang, Wenjing\|Song, Shanshan\|Liu, Yiting\|Liu, Xianying\|Xie, Yingjun
PMID:	27974949

395.
Journal:	Hypoxia (Auckl). 2016 Dec 8;4:163-174.
Title:	Combination effects of sorafenib with PI3K inhibitors under hypoxia in colorectal cancer.
Author:	Bhatia, Dimple R\|Thiagarajan, Padma
PMID:	27995152

396.
Journal:	Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Dec 28;41(12):1297-1304.
Title:	[Effect of jianpi-jiedu formula on tumor angiogenesis-relevant genes expression in colorectal cancer].
Author:	Mao, Dan\|Lei, Sanlin\|Ma, Jin'an\|Shi, Li\|Zhang, Shaofan\|Huang, Jianhua\|Liu, Xinyi\|Ding, Dengfeng\|Zhang, Yingjin\|Feng, Lei\|Zhang, Sifang
PMID:	28070042

397.
Journal:	Oncol Lett. 2016 Dec;12(6):4665-4670.
Title:	Interleukin-6 promotes tumor progression in colitis-associated colorectal cancer through HIF-1alpha regulation.
Author:	Han, Jun\|Xi, Qiulei\|Meng, Qingyang\|Liu, Jingzheng\|Zhang, Yongxian\|Han, Yusong\|Zhuang, Qiulin\|Jiang, Yi\|Ding, Qiurong\|Wu, Guohao
PMID:	28105173

398.
Journal:	J Cancer Res Ther. 2016 Oct-Dec;12(4):1313-1317.
Title:	Evaluation of hypoxia inducible factor-1 alpha gene expression in colorectal cancer stages of Iranian patients.
Author:	Mansour, Reyhaneh Nassiri\|Enderami, Seyed Ehsan\|Ardeshirylajimi, Abdolreza\|Fooladsaz, Koorosh\|Fathi, Mojtaba\|Ganji, Shahla Moahammad
PMID:	28169245

399.
Journal:	Mol Carcinog. 2017 Jan;56(1):288-299.
Title:	Novel synthetic curcumin analogs as potent antiangiogenic agents in colorectal cancer.
Author:	Rajitha, Balney\|Nagaraju, Ganji Purnachandra\|Shaib, Walid L\|Alese, Olatunji B\|Snyder, James P\|Shoji, Mamoru\|Pattnaik, Subasini\|Alam, Afroz\|El-Rayes, Bassel F
PMID:	27128654

400.
Journal:	Hum Exp Toxicol. 2017 Jul;36(7):692-700.
Title:	Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.
Author:	Ranjbarnejad, T\|Saidijam, M\|Tafakh, M Sadat\|Pourjafar, M\|Talebzadeh, F\|Najafi, R
PMID:	27481098

401.
Journal:	Oncol Res. 2017 May 24;25(5):651-661.
Title:	Exosomes Derived From Hypoxic Colorectal Cancer Cells Promote Angiogenesis Through Wnt4-Induced beta-Catenin Signaling in Endothelial Cells.
Author:	Huang, Zhe\|Feng, Yong
PMID:	27712599

402.
Journal:	Cancer Res. 2017 Jan 15;77(2):268-278.
Title:	Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.
Author:	Reynaud, Caroline\|Ferreras, Laura\|Di Mauro, Paola\|Kan, Casina\|Croset, Martine\|Bonnelye, Edith\|Pez, Floriane\|Thomas, Clemence\|Aimond, Geraldine\|Karnoub, Antoine E\|Brevet, Marie\|Clezardin, Philippe
PMID:	27742687

403.
Journal:	J Pathol Transl Med. 2017 Jan;51(1):9-16.
Title:	Increased Expression of Thymosin beta4 Is Independently Correlated with Hypoxia Inducible Factor-1alpha (HIF-1alpha) and Worse Clinical Outcome in Human Colorectal Cancer.
Author:	Lee, Seung Yun\|Park, Mee Ja\|Lee, Hye Kyung\|Son, Hyun Jin\|Kim, Chang Nam\|Kim, Joo Heon\|Kang, Dong Wook
PMID:	27744656

404.
Journal:	Biomed Pharmacother. 2017 Jan;85:733-739.
Title:	NOX2-ROS-HIF-1alpha signaling is critical for the inhibitory effect of oleanolic acid on rectal cancer cell proliferation.
Author:	Guo, Yongfeng\|Han, Bing\|Luo, Kongliang\|Ren, Zhijian\|Cai, Lei\|Sun, Li
PMID:	27938946

405.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2017 Feb 8;46(2):93-97.
Title:	[Expression of hypoxia-inducible factor 1alpha, glucose transporter 1 and lactate dehydrogenase 5 in colorectal cancer and clinicopathologic significance].
Author:	Yang, T Y\|Hao, L S\|Guo, D Z
PMID:	28173667

406.
Journal:	Cell Rep. 2017 Feb 14;18(7):1699-1712.
Title:	The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1alpha Levels and Colorectal Cancer Cell Survival under Hypoxia.
Author:	Di Conza, Giusy\|Trusso Cafarello, Sarah\|Loroch, Stefan\|Mennerich, Daniela\|Deschoemaeker, Sofie\|Di Matteo, Mario\|Ehling, Manuel\|Gevaert, Kris\|Prenen, Hans\|Zahedi, Rene Peiman\|Sickmann, Albert\|Kietzmann, Thomas\|Moretti, Fabiola\|Mazzone, Massimiliano
PMID:	28199842

407.
Journal:	J Exp Clin Cancer Res. 2017 Feb 18;36(1):32.
Title:	Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1alpha stabilization.
Author:	Bruno, Tiziana\|Valerio, Mariacristina\|Casadei, Luca\|De Nicola, Francesca\|Goeman, Frauke\|Pallocca, Matteo\|Catena, Valeria\|Iezzi, Simona\|Sorino, Cristina\|Desantis, Agata\|Manetti, Cesare\|Blandino, Giovanni\|Floridi, Aristide\|Fanciulli, Maurizio
PMID:	28214471

408.
Journal:	Cell Physiol Biochem. 2017;41(4):1271-1284.
Title:	Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity.
Author:	Westendorf, Astrid M\|Skibbe, Kathrin\|Adamczyk, Alexandra\|Buer, Jan\|Geffers, Robert\|Hansen, Wiebke\|Pastille, Eva\|Jendrossek, Verena
PMID:	28278498

409.
Journal:	J Ethnopharmacol. 2017 May 5;203:27-38.
Title:	Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1alpha via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
Author:	Mi, Chunliu\|Ma, Juan\|Wang, Ke Si\|Zuo, Hong Xiang\|Wang, Zhe\|Li, Ming Yue\|Piao, Lian Xun\|Xu, Guang Hua\|Li, Xuezheng\|Quan, Zhe Shan\|Jin, Xuejun
PMID:	28341244

410.
Journal:	Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1154-H1162.
Title:	Increased hypoxia-inducible factor-1alpha in striated muscle of tumor-bearing mice.
Author:	Devine, Raymond D\|Bicer, Sabahattin\|Reiser, Peter J\|Wold, Loren E
PMID:	28341633

411.
Journal:	Cancer Chemother Pharmacol. 2017 Jun;79(6):1077-1085.
Title:	Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer.
Author:	Sadahiro, Sotaro\|Suzuki, T\|Tanaka, A\|Okada, K\|Saito, G\|Miyakita, H\|Ogimi, T\|Nagase, H
PMID:	28417167

412.
Journal:	Dokl Biochem Biophys. 2017 Jan;472(1):27-30.
Title:	Inhibition of P-glycoprotein stimulates cell death under Hypoxia-mimicking conditions.
Author:	Vdovin, A S\|Maximchik, P V\|Kulikov, A V\|Zhivotovsky, B D\|Gogvadze, V G
PMID:	28421447

413.
Journal:	Oncotarget. 2017 Mar 28;8(13):20543-20557.
Title:	Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis.
Author:	Cruz, Mart Dela\|Ledbetter, Sarah\|Chowdhury, Sanjib\|Tiwari, Ashish K\|Momi, Navneet\|Wali, Ramesh K\|Bliss, Charles\|Huang, Christopher\|Lichtenstein, David\|Bhattacharya, Swati\|Varma-Wilson, Anisha\|Backman, Vadim\|Roy, Hemant K
PMID:	28423551

414.
Journal:	Gastroenterology. 2017 Aug;153(2):505-520.
Title:	Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells.
Author:	Li, Huihui\|Rokavec, Matjaz\|Jiang, Longchang\|Horst, David\|Hermeking, Heiko
PMID:	28435028

415.
Journal:	Theranostics. 2017 Feb 27;7(5):1114-1132.
Title:	The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer.
Author:	Wu, De-Wei\|Lin, Po-Lin\|Wang, Lee\|Huang, Chi-Chou\|Lee, Huei
PMID:	28435452

416.
Journal:	Cell Death Dis. 2017 May 4;8(5):e2761.
Title:	MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis.
Author:	Xu, Wanfu\|Zhang, Zijing\|Zou, Kejian\|Cheng, Yang\|Yang, Min\|Chen, Huan\|Wang, Hongli\|Zhao, Junhong\|Chen, Peiyu\|He, Liying\|Chen, Xinwen\|Geng, Lanlan\|Gong, Sitang
PMID:	28471448

417.
Journal:	Anticancer Res. 2017 May;37(5):2425-2436.
Title:	Inhibition of Ubiquitin-conjugating Enzyme E2 May Activate the Degradation of Hypoxia-inducible Factors and, thus, Overcome Cellular Resistance to Radiation in Colorectal Cancer.
Author:	Gombodorj, Navchaa\|Yokobori, Takehiko\|Yoshiyama, Shinji\|Kawabata-Iwakawa, Reika\|Rokudai, Susumu\|Horikoshi, Ikuko\|Nishiyama, Masahiko\|Nakano, Takashi
PMID:	28476810

418.
Journal:	Cancer Lett. 2017 Aug 1;400:117-126.
Title:	Myocyte enhancer factor 2D promotes colorectal cancer angiogenesis downstream of hypoxia-inducible factor 1alpha.
Author:	Xiang, Junyu\|Sun, Hui\|Su, Li\|Liu, Limei\|Shan, Juanjuan\|Shen, Junjie\|Yang, Zhi\|Chen, Jun\|Zhong, Xing\|Avila, Matias A\|Yan, Xiaochu\|Liu, Chungang\|Qian, Cheng
PMID:	28478181

419.
Journal:	Cell Cycle. 2017 Jun 18;16(12):1193-1200.
Title:	The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia.
Author:	Zhang, Jun\|Zhou, Lanlan\|Zhao, Shuai\|Dicker, David T\|El-Deiry, Wafik S
PMID:	28486050

420.
Journal:	Int J Oncol. 2017 Jun;50(6):2191-2199.
Title:	Upregulation of circadian gene 'hClock' contribution to metastasis of colorectal cancer.
Author:	Wang, Yaping\|Sun, Ning\|Lu, Chao\|Bei, Yibing\|Qian, Ruizhe\|Hua, Luchun
PMID:	28498393

421.
Journal:	Bioorg Med Chem Lett. 2017 Jul 1;27(13):3026-3029.
Title:	Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells.
Author:	Lee, Sanghyuck\|Kwon, Oh Seok\|Lee, Chang-Soo\|Won, Misun\|Ban, Hyun Seung\|Ra, Choon Sup
PMID:	28526370

422.
Journal:	Pathol Res Pract. 2017 Jul;213(7):783-792.
Title:	Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1alpha, CXCR4 and CA9 in colorectal carcinoma.
Author:	Saka, Burcu\|Ekinci, Ozgur\|Dursun, Ayse\|Akyurek, Nalan
PMID:	28554753

423.
Journal:	BMC Genomics. 2017 May 30;18(1):421.
Title:	Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author:	Cong, Wang\|Meng, Xianglian\|Li, Jin\|Zhang, Qiushi\|Chen, Feng\|Liu, Wenjie\|Wang, Ying\|Cheng, Sipu\|Yao, Xiaohui\|Yan, Jingwen\|Kim, Sungeun\|Saykin, Andrew J\|Liang, Hong\|Shen, Li
PMID:	28558704

424.
Journal:	Oncotarget. 2017 Jul 4;8(27):44498-44510.
Title:	Cell type-dependent HIF1 alpha-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells.
Author:	Tatrai, Eniko\|Bartal, Alexandra\|Gacs, Alexandra\|Paku, Sandor\|Kenessey, Istvan\|Garay, Tamas\|Hegedus, Balazs\|Molnar, Eszter\|Cserepes, Mihaly T\|Hegedus, Zita\|Kucsma, Nora\|Szakacs, Gergely\|Tovari, Jozsef
PMID:	28562340

425.
Journal:	Cell Death Dis. 2017 Jun 1;8(6):e2843.
Title:	The novel hypoxia-inducible factor-1alpha inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Author:	Ban, Hyun Seung\|Kim, Bo-Kyung\|Lee, Hongsub\|Kim, Hwan Mook\|Harmalkar, Dipesh\|Nam, Miso\|Park, Song-Kyu\|Lee, Kiho\|Park, Joon-Tae\|Kim, Inhyub\|Lee, Kyeong\|Hwang, Geum-Sook\|Won, Misun
PMID:	28569777

426.
Journal:	Cell Death Dis. 2017 Jun 8;8(6):e2865.
Title:	Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1alpha-modulated fatty acid metabolism.
Author:	Ni, Ting\|He, Zihao\|Dai, Yuanyuan\|Yao, Jingyue\|Guo, Qinglong\|Wei, Libin
PMID:	28594405

427.
Journal:	PLoS One. 2017 Jun 8;12(6):e0179202.
Title:	Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author:	Mahfouz, Nadine\|Tahtouh, Roula\|Alaaeddine, Nada\|El Hajj, Joelle\|Sarkis, Riad\|Hachem, Ray\|Raad, Issam\|Hilal, George
PMID:	28594907

428.
Journal:	Int J Mol Sci. 2017 Jun 9;18(6). pii: ijms18061240.
Title:	Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.
Author:	Ulivi, Paola\|Scarpi, Emanuela\|Chiadini, Elisa\|Marisi, Giorgia\|Valgiusti, Martina\|Capelli, Laura\|Casadei Gardini, Andrea\|Monti, Manlio\|Ruscelli, Silvia\|Frassineti, Giovanni Luca\|Calistri, Daniele\|Amadori, Dino\|Passardi, Alessandro
PMID:	28598398

429.
Journal:	Cancer Lett. 2017 Sep 10;403:86-97.
Title:	Tanshinone IIA inhibits beta-catenin/VEGF-mediated angiogenesis by targeting TGF-beta1 in normoxic and HIF-1alpha in hypoxic microenvironments in human colorectal cancer.
Author:	Sui, Hua\|Zhao, Jihui\|Zhou, Lihong\|Wen, Haotian\|Deng, Wanli\|Li, Chunpu\|Ji, Qing\|Liu, Xuan\|Feng, Yuanyuan\|Chai, Ni\|Zhang, Qibo\|Cai, Jianfeng\|Li, Qi
PMID:	28602978

430.
Journal:	Oncol Rep. 2017 Jul;38(1):584-590.
Title:	KLF2 inhibits cell growth via regulating HIF-1alpha/Notch-1 signal pathway in human colorectal cancer HCT116 cells.
Author:	Wang, Hai-Gang\|Cao, Bin\|Zhang, Li-Xian\|Song, Nan\|Li, Hui\|Zhao, Wen-Zeng\|Li, Yan-Shu\|Ma, Shun-Mao\|Yin, Dong-Jian
PMID:	28628187

431.
Journal:	Gene. 2017 Sep 20;629:16-28.
Title:	Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia.
Author:	Bhan, Arunoday\|Deb, Paromita\|Shihabeddin, Nadine\|Ansari, Khairul I\|Brotto, Marco\|Mandal, Subhrangsu S
PMID:	28756022

432.
Journal:	Cell Signal. 2017 Nov;39:44-54.
Title:	15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1.
Author:	Tuncer, Sinem\|Keskus, Ayse Gokce\|Colakoglu, Melis\|Cimen, Ismail\|Yener, Caner\|Konu, Ozlen\|Banerjee, Sreeparna
PMID:	28757355

433.
Journal:	Oncogene. 2017 Nov 23;36(47):6555-6567.
Title:	Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1alpha/GP78 axis.
Author:	Lee, J H\|Han, Y-S\|Yoon, Y M\|Yun, C W\|Yun, S P\|Kim, S M\|Kwon, H Y\|Jeong, D\|Baek, M J\|Lee, H J\|Lee, S-J\|Han, H J\|Lee, S H
PMID:	28759037

434.
Journal:	Chin J Nat Med. 2017 Jul;15(7):505-514.
Title:	Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways.
Author:	Asif, Muhammad\|Shafaei, Armaghan\|Abdul Majid, Aman Shah\|Ezzat, Mohammed Oday\|Dahham, Saad S\|Ahamed, Mohamed B Khadeer\|Oon, Chern Ein\|Abdul Majid, Amin Malik Shah
PMID:	28807224

435.
Journal:	Biomed Pharmacother. 2017 Nov;95:68-76.
Title:	Catalpol suppressed proliferation, growth and invasion of CT26 colon cancer by inhibiting inflammation and tumor angiogenesis.
Author:	Zhu, Pingting\|Wu, Yu\|Yang, Aihua\|Fu, Xingsheng\|Mao, Ming\|Liu, Zhaoguo
PMID:	28826099

436.
Journal:	J Biol Chem. 2017 Oct 13;292(41):17046-17056.
Title:	Hypoxia-inducible factor 2alpha (HIF-2alpha) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Author:	Ma, Xiaoya\|Zhang, Huabing\|Xue, Xiang\|Shah, Yatrik M
PMID:	28848049

437.
Journal:	Clin Sci (Lond). 2017 Sep 22;131(19):2439-2450.
Title:	Overexpression of TrpC5 promotes tumor metastasis via the HIF-1alpha-Twist signaling pathway in colon cancer.
Author:	Chen, Zhen\|Zhu, Yaodan\|Dong, Yongfei\|Zhang, Peng\|Han, Xiping\|Jin, Jian\|Ma, Xin
PMID:	28864720

438.
Journal:	Mar Drugs. 2017 Sep 4;15(9). pii: md15090283.
Title:	Potential Application of Eicosapentaenoic Acid Monoacylglyceride in the Management of Colorectal Cancer.
Author:	Morin, Caroline\|Rodriguez, Enrique\|Blier, Pierre U\|Fortin, Samuel
PMID:	28869531

439.
Journal:	Theranostics. 2017 Aug 11;7(14):3415-3431.
Title:	Brusatol-Mediated Inhibition of c-Myc Increases HIF-1alpha Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia.
Author:	Oh, Eun-Taex\|Kim, Chan Woo\|Kim, Ha Gyeong\|Lee, Jae-Seon\|Park, Heon Joo
PMID:	28912885

440.
Journal:	Biochem Biophys Res Commun. 2017 Nov 4;493(1):461-467.
Title:	Identification of hypoxia-regulated angiogenic genes in colorectal cancer.
Author:	Zong, Shaoqi\|Li, Wen\|Li, Hongjia\|Han, Susu\|Liu, Shanshan\|Shi, Qi\|Hou, Fenggang
PMID:	28928094

441.
Journal:	J Mol Med (Berl). 2017 Dec;95(12):1341-1353.
Title:	Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis.
Author:	Andreucci, Elena\|Peppicelli, Silvia\|Carta, Fabrizio\|Brisotto, Giulia\|Biscontin, Eva\|Ruzzolini, Jessica\|Bianchini, Francesca\|Biagioni, Alessio\|Supuran, Claudiu T\|Calorini, Lido
PMID:	28929255

442.
Journal:	Photochem Photobiol Sci. 2017 Nov 8;16(11):1631-1642.
Title:	A novel HIF-1alpha/VMP1-autophagic pathway induces resistance to photodynamic therapy in colon cancer cells.
Author:	Rodriguez, M E\|Catrinacio, C\|Ropolo, A\|Rivarola, V A\|Vaccaro, M I
PMID:	28936522

443.
Journal:	Cancer Biomark. 2017 Dec 6;20(4):417-424.
Title:	Elevated serum level of lncRNA-HIF1A-AS1 as a novel diagnostic predictor for worse prognosis in colorectal carcinoma.
Author:	Gong, Wanjun\|Tian, Ming\|Qiu, Honggen\|Yang, Zhenhua
PMID:	28946548

444.
Journal:	Cancer Lett. 2017 Dec 1;410:82-91.
Title:	Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1alpha pathway.
Author:	Yoshikawa, Yoko\|Takano, Osamu\|Kato, Ichiro\|Takahashi, Yoshihisa\|Shima, Fumi\|Kataoka, Tohru
PMID:	28951129

445.
Journal:	Oncotarget. 2017 Aug 24;8(44):77474-77488.
Title:	STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1alpha/VEGF signaling pathway.
Author:	Liu, Yang\|Steinestel, Konrad\|Rouhi, Arefeh\|Armacki, Milena\|Diepold, Kristina\|Chiosis, Gabriela\|Simmet, Thomas\|Seufferlein, Thomas\|Azoitei, Ninel
PMID:	29100402

446.
Journal:	Eur J Radiol. 2017 Nov;96:109-114.
Title:	Correlations between the iodine concentrations from dual energy computed tomography and molecular markers Ki-67 and HIF-1alpha in rectal cancer: A preliminary study.
Author:	Fan, Shuxuan\|Li, Xubin\|Zheng, Lei\|Hu, Dongzhi\|Ren, Xiaoyi\|Ye, Zhaoxiang
PMID:	29103468

447.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2017 Jul;48(4):566-569.
Title:	[Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis].
Author:	Shi, Xiao-Ming\|Zhao, Wei\|Yang, Yong-Bin\|Lu, Bo-Nan
PMID:	29130678

448.
Journal:	Oncotarget. 2017 Sep 6;8(48):84258-84275.
Title:	GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions.
Author:	Bustos, Viviana\|Nolan, Aine M\|Nijhuis, Anke\|Harvey, Harry\|Parker, Alexandra\|Poulsom, Richard\|McBryan, Jean\|Thomas, Warren\|Silver, Andrew\|Harvey, Brian J
PMID:	29137421

449.
Journal:	Oncotarget. 2017 Sep 21;8(49):86296-86311.
Title:	Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Author:	Jongen, Jennifer M J\|van der Waals, Lizet M\|Trumpi, Kari\|Laoukili, Jamila\|Peters, Niek A\|Schenning-van Schelven, Susanne J\|Govaert, Klaas M\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	29156796

450.
Journal:	J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):923-927.
Title:	Autophagy-related gene expression in colorectal cancer patients.
Author:	Bednarczyk, M\|Muc-Wierzgon, M\|Waniczek, D\|Fatyga, E\|Klakla, K\|Mazurek, U\|Wierzgon, J
PMID:	29254294

451.
Journal:	BMC Cancer. 2017 Dec 28;17(1):899.
Title:	Recombinant human endostatin combined with radiotherapy inhibits colorectal cancer growth.
Author:	Zhang, Ke\|Wang, Ye\|Yu, Xiaoli\|Shi, Yanyan\|Yao, Yasai\|Wei, Xiaofang\|Ma, Xuezhen
PMID:	29282026

452.
Journal:	Eur J Nutr. 2018 Jun;57(4):1381-1395.
Title:	Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms.
Author:	Scarpa, Emanuele Salvatore\|Antonini, Elena\|Palma, Francesco\|Mari, Michele\|Ninfali, Paolino
PMID:	28283822

453.
Journal:	Oncogene. 2018 Feb 1;37(5):601-615.
Title:	The extracellular matrix protein mindin attenuates colon cancer progression by blocking angiogenesis via Egr-1-mediated regulation.
Author:	Wang, L-F\|Liu, Y-S\|Yang, B\|Li, P\|Cheng, X-S\|Xiao, C-X\|Liu, J-J\|Li, S\|Ren, J-L\|Guleng, B
PMID:	28991232

454.
Journal:	Biochimie. 2018 Jan;144:21-27.
Title:	LncRNA CPS1-IT1 suppresses EMT and metastasis of colorectal cancer by inhibiting hypoxia-induced autophagy through inactivation of HIF-1alpha.
Author:	Zhang, Wei\|Yuan, Weitang\|Song, Junmin\|Wang, Shijun\|Gu, Xiaoming
PMID:	29017924

455.
Journal:	Clin Cancer Res. 2018 Jan 1;24(1):169-180.
Title:	Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.
Author:	Casillas, Andrea L\|Toth, Rachel K\|Sainz, Alva G\|Singh, Neha\|Desai, Ankit A\|Kraft, Andrew S\|Warfel, Noel A
PMID:	29084916

456.
Journal:	Carcinogenesis. 2018 Feb 9;39(2):272-282.
Title:	CD177+ neutrophils suppress epithelial cell tumourigenesis in colitis-associated cancer and predict good prognosis in colorectal cancer.
Author:	Zhou, Guangxi\|Peng, Kangsheng\|Song, Yang\|Yang, Wenjing\|Shu, Weigang\|Yu, Tianming\|Yu, Lin\|Lin, Moubin\|Wei, Qing\|Chen, Chunqiu\|Yin, Lu\|Cong, Yingzi\|Liu, Zhanju
PMID:	29228136

457.
Journal:	Br J Pharmacol. 2018 Mar;175(6):877-890.
Title:	Involvement of CYP1B1 in interferon gamma-induced alterations of epithelial barrier integrity.
Author:	Alhouayek, Mireille\|Gouveia-Figueira, Sandra\|Hammarstrom, Marie-Louise\|Fowler, Christopher J
PMID:	29232759

458.
Journal:	Int J Oncol. 2018 Feb;52(2):453-460.
Title:	Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer.
Author:	Nishizawa, Yujiro\|Konno, Masamitsu\|Asai, Ayumu\|Koseki, Jun\|Kawamoto, Koichi\|Miyoshi, Norikatsu\|Takahashi, Hidekazu\|Nishida, Naohiro\|Haraguchi, Naotsugu\|Sakai, Daisuke\|Kudo, Toshihiro\|Hata, Taishi\|Matsuda, Chu\|Mizushima, Tsunekazu\|Satoh, Taroh\|Doki, Yuichi
PMID:	29345294

459.
Journal:	Oncotarget. 2017 Dec 22;9(4):4998-5015.
Title:	Osteopontin-integrin engagement induces HIF-1alpha-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
Author:	Fan, Chi-Shuan\|Chen, Wei-Shone\|Chen, Li-Li\|Chen, Chia-Chi\|Hsu, Yu-Ting\|Chua, Kee Voon\|Wang, Horng-Dar\|Huang, Tze-Sing
PMID:	29435158

460.
Journal:	Oncol Lett. 2018 Mar;15(3):3639-3645.
Title:	Etaypoxia-inducible factor 1-alpha promotes colon cell proliferation and migration by upregulating AMPK-related protein kinase 5 under hypoxic conditions.
Author:	Peng, Ji Kui\|Shen, Shi Qiang\|Wang, Ju\|Jiang, Hong Wei\|Wang, Yong Qiang
PMID:	29467884

461.
Journal:	Mol Cancer Ther. 2018 Apr;17(4):838-848.
Title:	MCT4 Expression Is a Potential Therapeutic Target in Colorectal Cancer with Peritoneal Carcinomatosis.
Author:	Kim, Hee Kyung\|Lee, InKyoung\|Bang, Heejin\|Kim, Hee Cheol\|Lee, Woo Yong\|Yun, Seong Hyeon\|Lee, Jeeyun\|Lee, Su Jin\|Park, Young Suk\|Kim, Kyoung-Mee\|Kang, Won Ki
PMID:	29483215

462.
Journal:	Oncol Rep. 2018 May;39(5):2436-2442.
Title:	Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells.
Author:	Mao, Liyuan\|Chen, Qiongyun\|Gong, Ke\|Xu, Xiaolin\|Xie, Yurou\|Zhang, Wenqing\|Cao, Hanwei\|Hu, Tianhui\|Hong, Xiaoting\|Zhan, Yan-Yan
PMID:	29565467

463.
Journal:	Cell Physiol Biochem. 2018;46(2):492-504.
Title:	Propofol Disrupts Aerobic Glycolysis in Colorectal Cancer Cells via Inactivation of the NMDAR-CAMKII-ERK Pathway.
Author:	Chen, Xiangyuan\|Wu, Qichao\|Sun, Pengfei\|Zhao, Yanjun\|Zhu, Minmin\|Miao, Changhong
PMID:	29614493

464.
Journal:	Food Chem Toxicol. 2018 Jun;116(Pt B):70-76.
Title:	Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1alpha accumulation and VEGF expression.
Author:	Lee, Suk-Young\|Kim, Hong Jun\|Oh, Sang Cheul\|Lee, Dae-Hee
PMID:	29630948

465.
Journal:	J Inflamm (Lond). 2018 Apr 6;15:7.
Title:	Functional role of microRNA-135a in colitis.
Author:	Lou, Chunyan\|Li, Yanyang
PMID:	29636643

466.
Journal:	Oncotarget. 2018 Apr 6;9(26):18510-18517.
Title:	Histogram analysis of ADC in rectal cancer: associations with different histopathological findings including expression of EGFR, Hif1-alpha, VEGF, p53, PD1, and KI 67. A preliminary study.
Author:	Meyer, Hans Jonas\|Hohn, Annekathrin\|Surov, Alexey
PMID:	29719621

467.
Journal:	Int J Mol Med. 2018 Aug;42(2):935-945.
Title:	Role of TXNDC5 in tumorigenesis of colorectal cancer cells: In vivo and in vitro evidence.
Author:	Tan, Fengbo\|Zhu, Hong\|He, Xiao\|Yu, Nanhui\|Zhang, Xingwen\|Xu, Haifan\|Pei, Haiping
PMID:	29749460

468.
Journal:	Sci Rep. 2018 May 24;8(1):8089.
Title:	Role of Kupffer cells in the progression of CRC liver metastases after the first stage of ALPPS.
Author:	Garcia-Perez, Rocio\|Ferrer Fabrega, Joana\|Varona-Bosque, Aranzazu\|Martinez, Carlos Manuel\|Revilla-Nuin, Beatriz\|Cabellos, Laia\|Pena, Romina\|Vilana, Ramon\|Gonzalez-Abos, Carolina\|Garcia-Valdecasas, Juan Carlos\|Fuster Obregon, Jose
PMID:	29795479

469.
Journal:	Anticancer Res. 2018 Jun;38(6):3323-3331.
Title:	SN-38 Acts as a Radiosensitizer for Colorectal Cancer by Inhibiting the Radiation-induced Up-regulation of HIF-1alpha.
Author:	Okuno, Takayuki\|Kawai, Kazushige\|Hata, Keisuke\|Murono, Koji\|Emoto, Shigenobu\|Kaneko, Manabu\|Sasaki, Kazuhito\|Nishikawa, Takeshi\|Tanaka, Toshiaki\|Nozawa, Hiroaki
PMID:	29848680

470.
Journal:	J Ethnopharmacol. 2018 Oct 5;224:140-148.
Title:	Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1alpha/VEGF pathway.
Author:	Peng, Weijun\|Zhang, Shaofang\|Zhang, Zheyu\|Xu, Panpan\|Mao, Dan\|Huang, Siqi\|Chen, Biyue\|Zhang, Chunhu\|Zhang, Sifang
PMID:	29852266

471.
Journal:	Cell Commun Signal. 2018 Jun 8;16(1):26.
Title:	Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1alpha axis.
Author:	Li, Qingguo\|Li, Yaqi\|Liang, Lei\|Li, Jing\|Luo, Dakui\|Liu, Qi\|Cai, Sanjun\|Li, Xinxiang
PMID:	29884183

472.
Journal:	Anticancer Agents Med Chem. 2018 Jun 10. pii: ACAMC-EPUB-91045.
Title:	Verbascoside attenuates Rac-1 and HIF-1alpha signaling cascade in colorectal cancer cells.
Author:	Nabiuni, Mohammad\|Seyfi, Danial\|Behzad, Seyed Bahram\|Parivar, Kazem\|Tahmaseb, Mohammad\|Amini, Elaheh
PMID:	29886834

473.
Journal:	Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5990-E5999.
Title:	Hypoxic tumor microenvironment activates GLI2 via HIF-1alpha and TGF-beta2 to promote chemoresistance in colorectal cancer.
Author:	Tang, Yen-An\|Chen, Yu-Feng\|Bao, Yi\|Mahara, Sylvia\|Yatim, Siti Maryam J M\|Oguz, Gokce\|Lee, Puay Leng\|Feng, Min\|Cai, Yu\|Tan, Ern Yu\|Fong, Sau Shung\|Yang, Zi-Huan\|Lan, Ping\|Wu, Xiao-Jian\|Yu, Qiang
PMID:	29891662

474.
Journal:	Int J Biol Sci. 2018 May 12;14(7):726-735.
Title:	FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1alpha/CEACAM5 functional axis.
Author:	Li, Qingguo\|Li, Yaqi\|Li, Jing\|Ma, Yanlei\|Dai, Weixing\|Mo, Shaobo\|Xu, Ye\|Li, Xinxiang\|Cai, Sanjun
PMID:	29910683

475.
Journal:	Oncol Lett. 2018 Jun;15(6):10084-10090.
Title:	Acriflavine enhances the antitumor activity of the chemotherapeutic drug 5-fluorouracil in colorectal cancer cells.
Author:	Zargar, Parisa\|Ghani, Esmaeel\|Mashayekhi, Farideh Jalali\|Ramezani, Amin\|Eftekhar, Ebrahim
PMID:	29928378

476.
Journal:	Cancer Lett. 2018 Oct 1;433:165-175.
Title:	Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells.
Author:	Liang, Kang-Hao\|Tso, Hsien-Cheng\|Hung, Shao-Hsi\|Kuan, I-I\|Lai, Jun-Kai\|Ke, Feng-Yi\|Chuang, Yi-Ting\|Liu, I-Ju\|Wang, Yi-Ping\|Chen, Ruey-Hwa\|Wu, Han-Chung
PMID:	29981429

477.
Journal:	J Ginseng Res. 2018 Jul;42(3):288-297.
Title:	Korean Red Ginseng extract reduces hypoxia-induced epithelial-mesenchymal transition by repressing NF-kappaB and ERK1/2 pathways in colon cancer.
Author:	Kim, Eui Joo\|Kwon, Kwang An\|Lee, Young Eun\|Kim, Ju Hyun\|Kim, Se-Hee\|Kim, Jung Ho
PMID:	29983610

478.
Journal:	EBioMedicine. 2018 Aug;34:35-45.
Title:	Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Author:	Hu, Xiang\|Li, Ya-Qi\|Li, Qing-Guo\|Ma, Yan-Lei\|Peng, Jun-Jie\|Cai, San-Jun
PMID:	30037719

479.
Journal:	Biosci Rep. 2018 Jul 23. pii: BSR20180268.
Title:	The SLC34A2-ROS-HIF-1-induced upregulation of EZH2 expression promotes proliferation and chemo-resistance to apoptosis in colorectal cancer.
Author:	Li, Xu\|Xing, Junjie\|Wang, Hantao\|Yu, Enda
PMID:	30038060

480.
Journal:	Cell Physiol Biochem. 2018;48(6):2429-2440.
Title:	SRGN Promotes Colorectal Cancer Metastasis as a Critical Downstream Target of HIF-1alpha.
Author:	Xu, Yang\|Xu, Jie\|Yang, Yanfang\|Zhu, Lei\|Li, Xubin\|Zhao, Weipeng
PMID:	30121667

481.
Journal:	Biomed Pharmacother. 2018 Nov;107:1447-1453.
Title:	Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Author:	Wu, Yan-Yan\|Li, Tong-Ming\|Zang, Lin-Quan\|Liu, Bing\|Wang, Gui-Xiang
PMID:	30257361

482.
Journal:	Onco Targets Ther. 2018 Sep 20;11:6049-6056.
Title:	Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature.
Author:	Gallo, Stefania\|Arcidiacono, Maria Vittoria\|Tisato, Veronica\|Piva, Roberta\|Penolazzi, Letizia\|Bosi, Cristina\|Feo, Carlo V\|Gafa, Roberta\|Secchiero, Paola
PMID:	30275709

483.
Journal:	Cancer Lett. 2018 Oct 17;440-441:145-155.
Title:	A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53.
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PMID:	30339780

484.
Journal:	Mol Cell Biochem. 2018 Oct 24. pii: 10.1007/s11010-018-3462-1.
Title:	Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1alpha-VEGF signaling pathway.
Author:	Sabry, Dina\|El-Deek, Sahar E M\|Maher, Moataz\|El-Baz, Mona A H\|El-Bader, Hala M\|Amer, Eman\|Hassan, Elham A\|Fathy, Wael\|El-Deek, Heba E M
PMID:	30357530

485.
Journal:	J Cell Physiol. 2018 Oct 26.
Title:	Tet methylcytosine dioxygenase 1 promotes hypoxic gene induction and cell migration in colon cancer.
Author:	Ma, Ling\|Qi, Tianyang\|Wang, Shensen\|Hao, Miao\|Sakhawat, Ali\|Liang, Tianya\|Zhang, Lin\|Cong, Xianling\|Huang, Yinghui
PMID:	30367454

486.
Journal:	Int Immunopharmacol. 2018 Oct 30;65:429-437.
Title:	Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1alpha nuclear translocation.
Author:	Zhang, Lin\|Chen, Chang\|Duanmu, Jiaxin\|Wu, Yan\|Tao, Jinhua\|Yang, Aihua\|Yin, Xiaoqin\|Xiong, Biao\|Gu, Jingya\|Li, Chunling\|Liu, Zhaoguo
PMID:	30388517