Primary Site >> Biliary tract Cancer

Gene >> HIF1A

Journal: World J Gastroenterol. 2005 Aug 14;11(30):4644-9.
Title: Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion.
Author: Pinlaor, Somchai|Sripa, Banchob|Ma, Ning|Hiraku, Yusuke|Yongvanit, Puangrat|Wongkham, Sopit|Pairojkul, Chawalit|Bhudhisawasdi, Vajarabhongsa|Oikawa, Shinji|Murata, Mariko|Semba, Reiji|Kawanishi, Shosuke
PMID: 16094703
Journal: J Surg Oncol. 2006 Sep 1;94(3):242-7.
Title: Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas.
Author: Giatromanolaki, A|Sivridis, E|Simopoulos, C|Polychronidis, A|Gatter, K C|Harris, A L|Koukourakis, M I
PMID: 16900513
Journal: J Gastroenterol Hepatol. 2008 Mar;23(3):491-7.
Title: Heparanase expression in gallbladder carcinoma and its correlation to prognosis.
Author: Wu, Wujun|Pan, Cheng'en|Yu, Haibo|Gong, Huilin|Wang, Youli
PMID: 17524042
Journal: Int J Clin Oncol. 2010 Feb;15(1):59-64.
Title: Expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) in patients with the gallbladder carcinoma.
Author: Batmunkh, Erdenebulgan|Shimada, Mitsuo|Morine, Yuji|Imura, Satoru|Kanemura, Hirofumi|Arakawa, Yusuke|Hanaoka, Jun|Kanamoto, Mami|Sugimoto, Koji|Nishi, Masaaki
PMID: 20082206
Journal: Eur J Surg Oncol. 2011 Jan;37(1):80-6.
Title: The prognostic relevance of tumor hypoxia markers in resected carcinoma of the gallbladder.
Author: Sergeant, G|Lerut, E|Ectors, N|Hendrickx, T|Aerts, R|Topal, B
PMID: 21109386
Journal: Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1439-44.
Title: Hypoxia inducible factor expression in intrahepatic cholangiocarcinoma.
Author: Morine, Yuji|Shimada, Mitsuo|Utsunomiya, Tohru|Imura, Satoru|Ikemoto, Tetsuya|Mori, Hiroki|Hanaoka, Jun|Kanamoto, Mami|Iwahashi, Shuichi|Miyake, Hidenori
PMID: 21940327
Journal: Surgery. 2012 Mar;151(3):412-9.
Title: Role of histone deacetylase expression in intrahepatic cholangiocarcinoma.
Author: Morine, Yuji|Shimada, Mitsuo|Iwahashi, Shuichi|Utsunomiya, Tohru|Imura, Satoru|Ikemoto, Tetsuya|Mori, Hiroki|Hanaoka, Jun|Miyake, Hidenori
PMID: 21982637
Journal: Oncol Rep. 2012 Jun;27(6):1990-2002.
Title: Overexpression of HIF-1alpha in primary gallbladder carcinoma and its relation to vasculogenic mimicry and unfavourable prognosis.
Author: Sun, Wei|Shen, Zhen-Yu|Zhang, Hui|Fan, Yue-Zu|Zhang, Wen-Zhong|Zhang, Jing-Tao|Lu, Xing-Sui|Ye, Chun
PMID: 22470047
Journal: Cell Biol Int. 2013 Feb;37(2):121-5.
Title: Mucins 1-shRNA inhibit the proliferation and HIF-1alpha protein expression on human cholangiocarcinoma cells.
Author: Li, Zhuo-Ri|Wei, Jia-Li|Li, Zhen-Zhen|Li, Shu-Fang
PMID: 23339102
Journal: PLoS One. 2013;8(1):e54377.
Title: Characterization of two novel cell lines with distinct heterogeneity derived from a single human bile duct carcinoma.
Author: Wang, Jinghan|Li, Linfang|Zhang, Keqiang|Yu, Yong|Li, Bin|Li, Jiang|Yan, Zi|Hu, Zhenli|Yen, Yun|Wu, Mengchao|Jiang, Xiaoqing|Qian, Qijun
PMID: 23382894
Journal: PLoS One. 2013 May 21;8(5):e64186.
Title: EGFR, FLT1 and heparanase as markers identifying patients at risk of short survival in cholangiocarcinoma.
Author: Hoffmann, Andreas-Claudius|Goekkurt, Eray|Danenberg, Peter V|Lehmann, Sylvia|Ehninger, Gerhard|Aust, Daniela E|Stoehlmacher-Williams, Jan
PMID: 23704979
Journal: Hum Pathol. 2014 Aug;45(8):1610-7.
Title: Different expression of glucose transporters in the progression of intrahepatic cholangiocarcinoma.
Author: Kubo, Yuichiro|Aishima, Shinichi|Tanaka, Yuki|Shindo, Koji|Mizuuchi, Yusuke|Abe, Koichiro|Shirabe, Ken|Maehara, Yoshihiko|Honda, Hiroshi|Oda, Yoshinao
PMID: 24824030
Journal: Eur J Cancer. 2014 Dec;50(18):3125-35.
Title: Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme.
Author: Moehler, M|Maderer, A|Schimanski, C|Kanzler, S|Denzer, U|Kolligs, F T|Ebert, M P|Distelrath, A|Geissler, M|Trojan, J|Schutz, M|Berie, L|Sauvigny, C|Lammert, F|Lohse, A|Dollinger, M M|Lindig, U|Duerr, E M|Lubomierski, N|Zimmermann, S|Wachtlin, D|Kaiser, A-
PMID: 25446376
Journal: Asian Pac J Cancer Prev. 2014;15(14):5873-8.
Title: High expression of HIF-1alpha, BNIP3 and PI3KC3: hypoxia-induced autophagy predicts cholangiocarcinoma survival and metastasis.
Author: Thongchot, Suyanee|Yongvanit, Puangrat|Loilome, Watcharin|Seubwai, Wanchana|Phunicom, Kutcharin|Tassaneeyakul, Wichittra|Pairojkul, Chawalit|Promkotra, Wisuttiphong|Techasen, Anchalee|Namwat, Nisana
PMID: 25081716
Journal: Int J Mol Sci. 2014 Jul 18;15(7):12778-90.
Title: Cordycepin down-regulates multiple drug resistant (MDR)/HIF-1alpha through regulating AMPK/mTORC1 signaling in GBC-SD gallbladder cancer cells.
Author: Wu, Wei-Ding|Hu, Zhi-Ming|Shang, Min-Jie|Zhao, Da-Jian|Zhang, Cheng-Wu|Hong, De-Fei|Huang, Dong-Sheng
PMID: 25046749
Journal: Oncol Rep. 2014 Jun;31(6):2611-8.
Title: Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines.
Author: Ling, Sunbin|Feng, Tingting|Ke, Qinghong|Fan, Ning|Li, Lei|Li, Zhongxing|Dong, Chengyong|Wang, Cong|Xu, Fei|Li, Yan|Wang, Liming
PMID: 24788596
Journal: Exp Cell Res. 2015 Mar 15;332(2):236-46.
Title: Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1alpha.
Author: Gao, Hui|Xie, Jing|Peng, Jianjun|Han, Yantao|Jiang, Qixiao|Han, Mei|Wang, Chunbo
PMID: 25499970
Journal: Oncotarget. 2015 Aug 7;6(22):18905-20.
Title: Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.
Author: Wang, Jinghan|Zhang, Keqiang|Wang, Jinhui|Wu, Xiwei|Liu, Xiyong|Li, Bin|Zhu, Yan|Yu, Yong|Cheng, Qingbao|Hu, Zhenli|Guo, Chao|Hu, Shuya|Mu, Bing|Tsai, Chun-Hao|Li, Jie|Smith, Lynne|Yang, Lu|Liu, Qi|Chu, Peiguo|Chang, Vincent|Zhang, Baihe|Wu, Mengchao|Jian
PMID: 26056085
Journal: PLoS One. 2015 Jul 24;10(7):e0132953.
Title: Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes.
Author: Sadot, Eran|Simpson, Amber L|Do, Richard K G|Gonen, Mithat|Shia, Jinru|Allen, Peter J|D'Angelica, Michael I|DeMatteo, Ronald P|Kingham, T Peter|Jarnagin, William R
PMID: 26207380
Journal: Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):79-85.
Title: NOX1 mediates chemoresistance via HIF1alpha/MDR1 pathway in gallbladder cancer.
Author: Zhan, Ming|Wang, Hui|Chen, Tao|Chen, Wei|Yang, Linhua|He, Min|Xu, Sunwang|Wang, Jian
PMID: 26545779
Journal: Oncotarget. 2016 Jan 19;7(3):3341-56.
Title: Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy.
Author: Weijer, Ruud|Broekgaarden, Mans|Krekorian, Massis|Alles, Lindy K|van Wijk, Albert C|Mackaaij, Claire|Verheij, Joanne|van der Wal, Allard C|van Gulik, Thomas M|Storm, Gert|Heger, Michal
PMID: 26657503
Journal: Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):73-83. eCollection 2016.
Title: Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.
Author: Kwee, Sandi A|Okimoto, Gordon S|Chan, Owen Tm|Tiirikainen, Maarit|Wong, Linda L
PMID: 27069767
Journal: Open Biol. 2017 Jan;7(1). pii: rsob.160247.
Title: Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1alpha via miR-138.
Author: Cai, Qiang|Wang, Zhenqiang|Wang, Shouhua|Weng, Mingzhe|Zhou, Di|Li, Chen|Wang, Jiandong|Chen, Erzhen|Quan, Zhiwei
PMID: 28077595
Journal: Cell Physiol Biochem. 2017;42(5):2078-2092.
Title: MiR-143-5p Deficiency Triggers EMT and Metastasis by Targeting HIF-1alpha in Gallbladder Cancer.
Author: He, Min|Zhan, Ming|Chen, Wei|Xu, Sunwang|Long, Manmei|Shen, Hui|Shi, Yongheng|Liu, Qiang|Mohan, Man|Wang, Jian
PMID: 28803245