Primary Site >> Biliary tract Cancer

Gene >> HIF1A

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Ref: Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion.
PMID: 16094703
 Ref: Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas.
PMID: 16900513
 Ref: Heparanase expression in gallbladder carcinoma and its correlation to prognosis.
PMID: 17524042
 Ref: Expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) in patients with the gallbladder carcinoma.
PMID: 20082206
 Ref: The prognostic relevance of tumor hypoxia markers in resected carcinoma of the gallbladder.
PMID: 21109386
Ref: Hypoxia inducible factor expression in intrahepatic cholangiocarcinoma.
PMID: 21940327
 Ref: Role of histone deacetylase expression in intrahepatic cholangiocarcinoma.
PMID: 21982637
Ref: Overexpression of HIF-1alpha in primary gallbladder carcinoma and its relation to vasculogenic mimicry and unfavourable prognosis.
PMID: 22470047
 Ref: Mucins 1-shRNA inhibit the proliferation and HIF-1alpha protein expression on human cholangiocarcinoma cells.
PMID: 23339102
Ref: Characterization of two novel cell lines with distinct heterogeneity derived from a single human bile duct carcinoma.
PMID: 23382894
Ref: EGFR, FLT1 and heparanase as markers identifying patients at risk of short survival in cholangiocarcinoma.
PMID: 23704979
 Ref: Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines.
PMID: 24788596
Ref: Different expression of glucose transporters in the progression of intrahepatic cholangiocarcinoma.
PMID: 24824030
Ref: Cordycepin down-regulates multiple drug resistant (MDR)/HIF-1alpha through regulating AMPK/mTORC1 signaling in GBC-SD gallbladder cancer cells.
PMID: 25046749
Ref: High expression of HIF-1alpha, BNIP3 and PI3KC3: hypoxia-induced autophagy predicts cholangiocarcinoma survival and metastasis.
PMID: 25081716
Ref: Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme.
PMID: 25446376
 Ref: Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1alpha.
PMID: 25499970
Ref: Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.
PMID: 26056085
Ref: Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes.
PMID: 26207380
Ref: NOX1 mediates chemoresistance via HIF1alpha/MDR1 pathway in gallbladder cancer.
PMID: 26545779
 Ref: Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy.
PMID: 26657503
Ref: Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.
PMID: 27069767
 Ref: Long non-coding RNA LINC00152 promotes gallbladder cancer metastasis and epithelial-mesenchymal transition by regulating HIF-1alpha via miR-138.
PMID: 28077595
Ref: MiR-143-5p Deficiency Triggers EMT and Metastasis by Targeting HIF-1alpha in Gallbladder Cancer.
PMID: 28803245