Primary Site >> Liver Cancer

Gene >> HGF

Journal: Eur J Immunol. 1988 Aug;18(8):1259-64.
Title: Interleukin 6, the third mediator of acute-phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 beta and tumor necrosis factor-alpha.
Author: Ramadori, G|Van Damme, J|Rieder, H|Meyer zum Buschenfelde, K H
PMID: 3138137
Journal: Prog Growth Factor Res. 1991;3(3):219-34.
Title: Growth factors in liver development, regeneration and carcinogenesis.
Author: Fausto, N
PMID: 1667366
Journal: Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):373-7.
Title: Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.
Author: Shiota, G|Rhoads, D B|Wang, T C|Nakamura, T|Schmidt, E V
PMID: 1309612
Journal: Osaka City Med J. 1994 Dec;40(2):53-69.
Title: Effect of intracellular pH and two growth factors, epidermal growth factor and human hepatocyte growth factor, on DNA synthesis in non-regenerating and regenerating hepatocytes and hepatoma cells.
Author: Yada, K
PMID: 7862427
Journal: Rinsho Byori. 1994 Oct;42(10):1001-2.
Title: [Development of diagnostic method for liver disease].
Author: Tameda, Y|Horiguchi, Y
PMID: 7996709
Journal: Carcinogenesis. 1994 Dec;15(12):2687-94.
Title: The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergize with epidermal growth factor to promote clonal expansion of initiated rat hepatocytes.
Author: James, N H|Roberts, R A
PMID: 8001222
Journal: Toxicology. 1995 Sep 1;102(1-2):223-37.
Title: Negative selection in hepatic tumor promotion in relation to cancer risk assessment.
Author: Andersen, M E|Mills, J J|Jirtle, R L|Greenlee, W F
PMID: 7482557
Journal: J Cell Physiol. 1995 Dec;165(3):459-67.
Title: Growth control and gene expression in a new hepatocellular carcinoma cell line, Hep40: inhibitory actions of vitamin K.
Author: Bouzahzah, B|Nishikawa, Y|Simon, D|Carr, B I
PMID: 7593224
Journal: J Med. 1995;26(5-6):295-308.
Title: Hepatocyte growth factor and acute phase proteins in patients with chronic liver diseases.
Author: Shiota, G|Umeki, K|Okano, J|Kawasaki, H
PMID: 8721905
Journal: Cancer Lett. 1996 Feb 6;99(2):177-83.
Title: Responsiveness of hepatocytes from dichloroacetic acid or phenobarbital treated mice to growth factors in primary culture.
Author: Tsai, W H|DeAngelo, A B
PMID: 8616822
Journal: Cell Growth Differ. 1996 Nov;7(11):1513-23.
Title: Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers.
Author: Sakata, H|Takayama, H|Sharp, R|Rubin, J S|Merlino, G|LaRochelle, W J
PMID: 8930401
Journal: Zhonghua Yi Xue Za Zhi. 1996 Nov;76(11):822-5.
Title: [Gene expression of HGF and its receptor in experimental hepatomas].
Author: Luo, Y|Wu, M|Chen, H
PMID: 9275531
Journal: Br J Cancer. 1997;75(1):47-53.
Title: Involvement of hepatocyte growth factor in increased integrin expression on HepG2 cells triggered by adhesion to endothelial cells.
Author: Kawakami-Kimura, N|Narita, T|Ohmori, K|Yoneda, T|Matsumoto, K|Nakamura, T|Kannagi, R
PMID: 9000597
Journal: Hepatology. 1997 Jul;26(1):59-66.
Title: Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines.
Author: Chen, Q|Seol, D W|Carr, B|Zarnegar, R
PMID: 9214452
Journal: Clin Cancer Res. 1997 Jul;3(7):1059-66.
Title: Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas.
Author: Kiss, A|Wang, N J|Xie, J P|Thorgeirsson, S S
PMID: 9815784
Journal: Int J Oncol. 1998 Mar;12(3):655-9.
Title: Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines.
Author: Kamiyama, T|Une, Y|Uchino, J|Hamada, J
PMID: 9472107
Journal: Gastroenterology. 1998 Apr;114(4):775-81.
Title: Hepatocyte growth factor stimulates DNA synthesis in rat preneoplastic hepatocytes but not in liver carcinoma cells.
Author: Ogasawara, H|Hiramoto, J|Takahashi, M|Shirahama, K|Furusaka, A|Hiyane, S|Nakada, T|Nagayama, K|Tanaka, T
PMID: 9516398
Journal: Exp Cell Res. 1998 Jun 15;241(2):445-57.
Title: Phenobarbital suppresses growth and accelerates restoration of differentiation markers of primary culture rat hepatocytes in the chemically defined hepatocyte growth medium containing hepatocyte growth factor and epidermal growth factor.
Author: Miyazaki, M|Mars, W M|Runge, D|Kim, T H|Bowen, W C|Michalopoulos, G K
PMID: 9637786
Journal: Gan To Kagaku Ryoho. 1998 Jul;25(9):1352-4.
Title: [Stimulation of asialoglycoprotein receptor activity after transcatheter arterial embolotherapy in clinical study and continuous infusion of human hepatocyte growth factor in rat].
Author: Hakawa, S K|Kouda, K|Tanaka, Y
PMID: 9703826
Journal: Liver. 1999 Apr;19(2):151-9.
Title: Expression of hepatocyte growth factor (HGF) and HGF receptor (c-met) proteins in liver diseases: an immunohistochemical study.
Author: Okano, J|Shiota, G|Kawasaki, H
PMID: 10220746
Journal: Int J Cancer. 2000 Sep 1;87(5):644-9.
Title: u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma.
Author: Tavian, D|De Petro, G|Benetti, A|Portolani, N|Giulini, S M|Barlati, S
PMID: 10925356
Journal: Int J Oncol. 2000 Oct;17(4):777-81.
Title: Hepatocarcinoma cells stimulate hepatocyte growth factor secretion in human liver myofibroblasts.
Author: Guirouilh, J|Castroviejo, M|Balabaud, C|Desmouliere, A|Rosenbaum, J
PMID: 10995891
Journal: Intervirology. 2001;44(1):36-42.
Title: Detection of serum and intrahepatic human hepatocyte growth factor in patients with type C liver diseases.
Author: Yamagami, H|Moriyama, M|Tanaka, N|Arakawa, Y
PMID: 11223718
Journal: In Vitro Cell Dev Biol Anim. 2001 Jan;37(1):17-25.
Title: Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma.
Author: Gil-Benso, R|Martinez-Lorente, A|Pellin-Perez, A|Navarro-Fos, S|Gregori-Romero, M A|Carda, C|Callaghan, R|Peydro-Olaya, A|Llombart-Bosch, A
PMID: 11249201
Journal: Mol Diagn. 2001 Mar;6(1):27-37.
Title: Comparative genomic hybridization of hepatocellular carcinoma: correlation with fluorescence in situ hybridization in paraffin-embedded tissue.
Author: Rao, U N|Gollin, S M|Beaves, S|Cieply, K|Nalesnik, M|Michalopoulos, G K
PMID: 11257209
Journal: Int J Oncol. 2001 Jul;19(1):83-8.
Title: Trans-resveratrol, a grapevine-derived polyphenol, blocks hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells.
Author: De Ledinghen, V|Monvoisin, A|Neaud, V|Krisa, S|Payrastre, B|Bedin, C|Desmouliere, A|Bioulac-Sage, P|Rosenbaum, J
PMID: 11408926
Journal: Biochem Biophys Res Commun. 2001 Sep 7;286(5):1123-30.
Title: Invasiveness of hepatocellular carcinoma cell lines: contribution of hepatocyte growth factor, c-met, and transcription factor Ets-1.
Author: Jiang, Y|Xu, W|Lu, J|He, F|Yang, X
PMID: 11527416
Journal: World J Gastroenterol. 2001 Dec;7(6):816-20.
Title: SF/HGF-c-Met autocrine and paracrine promote metastasis of hepatocellular carcinoma.
Author: Xie, Q|Liu, K D|Hu, M Y|Zhou, K
PMID: 11854908
Journal: Hepatology. 2002 May;35(5):1117-24.
Title: Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells.
Author: Abiru, Seigou|Nakao, Kazuhiko|Ichikawa, Tatsuki|Migita, Kiyoshi|Shigeno, Masaya|Sakamoto, Miyuki|Ishikawa, Hiroki|Hamasaki, Keisuke|Nakata, Keisuke|Eguchi, Katsumi
PMID: 11981761
Journal: World J Gastroenterol. 2002 Jun;8(3):385-92.
Title: The prognostic molecular markers in hepatocellular carcinoma.
Author: Qin, Lun-Xiu|Tang, Zhao-You
PMID: 12046056
Journal: Cancer. 2002 Aug 15;95(4):824-34.
Title: Serum concentrations of human hepatocyte growth factor is a useful indicator for predicting the occurrence of hepatocellular carcinomas in C-viral chronic liver diseases.
Author: Yamagamim, Hiroaki|Moriyama, Mitsuhiko|Matsumura, Hiroshi|Aoki, Hiroshi|Shimizu, Toshihiro|Saito, Takahide|Kaneko, Miki|Shioda, Atsuo|Tanaka, Naohide|Arakawa, Yasuyuki
PMID: 12209727
Journal: Hepatology. 2002 Nov;36(5):1089-97.
Title: Insulin-like growth factor I is a comitogen for hepatocyte growth factor in a rat model of hepatocellular carcinoma.
Author: Price, Julie A|Kovach, Stephen J|Johnson, Timothy|Koniaris, Leonidas G|Cahill, Paul A|Sitzmann, James V|McKillop, Iain H
PMID: 12395318
Journal: Mod Pathol. 2003 Jan;16(1):14-21.
Title: HGF, MET, and matrix-related proteases in hepatocellular carcinoma, fibrolamellar variant, cirrhotic and normal liver.
Author: Schoedel, Karen E|Tyner, Valerie Zajac|Kim, Tae-Hyoung|Michalopoulos, George K|Mars, Wendy M
PMID: 12527708
Journal: Biochem Biophys Res Commun. 2003 May 30;305(2):428-33.
Title: An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells.
Author: Hah, Nasun|Lee, Seung-Taek
PMID: 12745093
Journal: Hepatol Res. 2003 Dec;27(4):289-301.
Title: Induction of multiple matrix metalloproteinase genes in human hepatocellular carcinoma by hepatocyte growth factor via a transcription factor Ets-1.
Author: Ozaki, Iwata|Mizuta, Toshihiko|Zhao, Gang|Zhang, Hao|Yoshimura, Toru|Kawazoe, Seiji|Eguchi, Yuichiro|Yasutake, Tsutomu|Hisatomi, Akitaka|Sakai, Takahiro|Yamamoto, Kyosuke
PMID: 14662117
Journal: J Hepatol. 2004 Aug;41(2):267-73.
Title: SU5416 is a potent inhibitor of hepatocyte growth factor receptor (c-Met) and blocks HGF-induced invasiveness of human HepG2 hepatoma cells.
Author: Wang, Si Y|Chen, Bing|Zhan, Yi Q|Xu, Wang X|Li, Chang Y|Yang, Ri F|Zheng, Hong|Yue, Pei B|Larsen, Steven H|Sun, Hui B|Yang, Xiaoming
PMID: 15288476
Journal: Cancer Sci. 2004 Aug;95(8):666-73.
Title: Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines.
Author: Cheng, Jidong|Imanishi, Hiroyasu|Liu, Weidong|Nakamura, Hideji|Morisaki, Takayuki|Higashino, Kazuya|Hada, Toshikazu
PMID: 15298730
Journal: Hepatology. 2004 Sep;40(3):618-28.
Title: Negative regulation of hepatocellular carcinoma cell growth by signal regulatory protein alpha1.
Author: Yan, He-Xin|Wang, Hong-Yang|Zhang, Rui|Chen, Lei|Li, Bao-An|Liu, Shu-Qin|Cao, Hui-Fang|Qiu, Xiu-Hua|Shan, Yun-Feng|Yan, Zhong-Hua|Wu, Hong-Ping|Tan, Ye-Xiong|Wu, Meng-Chao
PMID: 15349900
Journal: Eur Surg Res. 2004 Sep-Oct;36(5):300-7.
Title: Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines.
Author: Efimova, Ekaterina A|Glanemann, M|Liu, L|Schumacher, G|Settmacher, U|Jonas, S|Langrehr, J M|Neuhaus, P|Nussler, A K
PMID: 15359093
Journal: Cancer Gene Ther. 2005 Feb;12(2):116-21.
Title: Vascular administration of adenoviral vector soaked in absorbable gelatin sponge particles (GSP) prolongs the transgene expression in hepatocytes.
Author: Park, Byeong-Ho|Lee, Jin-Hwa|Jeong, Jin-Sook|Rha, Seo-Hee|Kim, Seung-Eun|Kim, Jae-Seok|Kim, Jeong-Man|Hwang, Tae-Ho
PMID: 15578067
Journal: Cancer Gene Ther. 2005 Dec;12(12):954-62.
Title: Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK4 gene therapy.
Author: Heideman, Danielle A M|Overmeer, Renee M|van Beusechem, Victor W|Lamers, Wouter H|Hakvoort, Theodorus B M|Snijders, Peter J F|Craanen, Mikael E|Offerhaus, G Johan A|Meijer, Chris J L M|Gerritsen, Winald R
PMID: 15905856
Journal: Carcinogenesis. 2006 Jan;27(1):152-61.
Title: Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis.
Author: Drucker, Claudia|Parzefall, Wolfram|Teufelhofer, Olga|Grusch, Michael|Ellinger, Adolf|Schulte-Hermann, Rolf|Grasl-Kraupp, Bettina
PMID: 16081514
Journal: Chem Biol Interact. 2006 Mar 25;160(2):123-33.
Title: Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways.
Author: Lee, Wei-Jiunn|Wu, Lan-Feng|Chen, Wen-Kang|Wang, Chau-Jong|Tseng, Tsui-Hwa
PMID: 16458870
Journal: Hepatogastroenterology. 2006 Jan-Feb;53(67):115-9.
Title: The role of a protease inhibitor against hepatectomy.
Author: Gotohda, Naoto|Iwagaki, Hiromi|Ozaki, Michitaka|Konishi, Masaru|Nakagohri, Toshio|Takahashi, Shinichiro|Yagi, Takahito|Kinoshita, Taira|Tanaka, Noriaki
PMID: 16506388
Journal: Zhonghua Wai Ke Za Zhi. 2006 May 1;44(9):603-8.
Title: [Study on the prognostic value of hepatocyte growth factor and c-met for patients with hepatocellular carcinoma].
Author: Wu, Fu-sheng|Zheng, Shu-sen|Wu, Ling-jiao|Ding, Wei|Ma, Zhi-min|Wang, Zhao-ming|Teng, Li-song|Zhao, Wen-he
PMID: 16784653
Journal: Oncol Rep. 2006 Jul;16(1):25-31.
Title: Effect of hepatocyte growth factor on endogenous hepatocarcinogenesis in rats fed a choline-deficient L-amino acid-defined diet.
Author: Nakanishi, Chihiro|Moriuchi, Akihiro|Ido, Akio|Numata, Masatsugu|Kim, Il-Deok|Kusumoto, Kazunori|Hasuike, Satoru|Abe, Hiroo|Nagata, Kenji|Akiyama, Yutaka|Uto, Hirofumi|Kataoka, Hiroaki|Tsubouchi, Hirohito
PMID: 16786119
Journal: Oncogene. 2006 Jun 26;25(27):3787-800.
Title: Dysregulation of growth factor signaling in human hepatocellular carcinoma.
Author: Breuhahn, K|Longerich, T|Schirmacher, P
PMID: 16799620
Journal: J Hepatol. 2006 Nov;45(5):688-95.
Title: Blockage of HGF/c-Met system by gene therapy (adenovirus-mediated NK4 gene) suppresses hepatocellular carcinoma in mice.
Author: Son, Gakuhei|Hirano, Tadamichi|Seki, Ekihiro|Iimuro, Yuji|Nukiwa, Toshihiro|Matsumoto, Kunio|Nakamura, Toshikazu|Fujimoto, Jiro
PMID: 16839638
Journal: Hepatology. 2006 Oct;44(4):992-1002.
Title: Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice.
Author: Apte, Udayan|Zeng, Gang|Muller, Peggy|Tan, Xinping|Micsenyi, Amanda|Cieply, Benjamin|Dai, Chunsun|Liu, Youhua|Kaestner, Klaus H|Monga, Satdarshan P S
PMID: 17006939
Journal: Gastroenterology. 2006 Dec;131(6):1758-67.
Title: A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
Author: Llovet, Josep M|Chen, Yingbei|Wurmbach, Elisa|Roayaie, Sasan|Fiel, M Isabel|Schwartz, Myron|Thung, Swan N|Khitrov, Gregory|Zhang, Weijia|Villanueva, Augusto|Battiston, Carlo|Mazzaferro, Vincenzo|Bruix, Jordi|Waxman, Samuel|Friedman, Scott L
PMID: 17087938
Journal: Life Sci. 2007 Jan 9;80(5):484-92.
Title: Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis.
Author: Zhao, Qing-Tao|Yue, Shu-Qiang|Cui, Zhong|Wang, Qi|Cui, Xin|Zhai, Hui-Hong|Zhang, Li-Hui|Dou, Ke-Feng
PMID: 17097688
Journal: Eur J Surg Oncol. 2007 Mar;33(2):208-12.
Title: Evaluation of interleukin-6, interleukin-10 and human hepatocyte growth factor as tumor markers for hepatocellular carcinoma.
Author: Hsia, C-Y|Huo, T-I|Chiang, S-Y|Lu, M-F|Sun, C-L|Wu, J-C|Lee, P-C|Chi, C-W|Lui, W-Y|Lee, S-D
PMID: 17140760
Journal: Zhonghua Gan Zang Bing Za Zhi. 2007 Jun;15(6):441-4.
Title: [Molecular mechanisms of DHEA and DHEAs on apoptosis and cell cycle arrest via Akt pathway in hepatoma cell lines].
Author: Jiang, Yan-fang|Zhao, Ping-wei|Tan, Yan|Liu, Li-hua|Li, Ming-hui|Matsuzaki, Yasushi|Niu, Jun-qi
PMID: 17594810
Journal: Transplantation. 2007 Nov 27;84(10):1262-71.
Title: Angiogenesis soluble factors as hepatocellular carcinoma noninvasive markers for monitoring hepatitis C virus cirrhotic patients awaiting liver transplantation.
Author: Mas, Valeria R|Maluf, Daniel G|Archer, Kellie J|Yanek, Kenneth C|Fisher, Robert A
PMID: 18049111
Journal: Gastrointest Cancer Res. 2007;1(4 Suppl 2):S13-21.
Title: Liver stem cells and molecular signaling pathways in hepatocellular carcinoma.
Author: Kitisin, Krit|Pishvaian, Michael J|Johnson, Lynt B|Mishra, Lopa
PMID: 19360142
Journal: Eur J Surg Oncol. 2008 Mar;34(3):333-8.
Title: Significance of serum hepatocyte growth factor levels in patients with hepatocellular carcinoma undergoing hepatic resection.
Author: Chau, G-Y|Lui, W-Y|Chi, C-W|Chau, Y-P|Li, A-F|Kao, H-L|Wu, C-W
PMID: 17218078
Journal: Biochem J. 2008 Apr 15;411(2):379-86.
Title: Involvement of Egr-1 in HGF-induced elevation of the human 5alpha-R1 gene in human hepatocellular carcinoma cells.
Author: Rui, Caixia|Li, Changyan|Xu, Wangxiang|Zhan, Yiqun|Li, Yonghui|Yang, Xiaoming
PMID: 18215136
Journal: Clin Biochem. 2008 Aug;41(12):1008-14.
Title: Molecular evaluation of apoptotic versus antiapoptotic angiogenic markers in hepatocellular carcinoma.
Author: Abdel Aziz, Mohamed T|El-Miligy, Dawlat|Amin, Mona A|El Ansari, Amina|Ahmed, Hanan H|Marzouk, Samer|Sabry, Dina
PMID: 18339319
Journal: Br J Cancer. 2008 Jul 8;99(1):151-9.
Title: New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis.
Author: Sagmeister, S|Eisenbauer, M|Pirker, C|Mohr, T|Holzmann, K|Zwickl, H|Bichler, C|Kandioler, D|Wrba, F|Mikulits, W|Gerner, C|Shehata, M|Majdic, O|Streubel, B|Berger, W|Micksche, M|Zatloukal, K|Schulte-Hermann, R|Grasl-Kraupp, B
PMID: 18594539
Journal: Sci China C Life Sci. 2008 Jul;51(7):648-54.
Title: KAI1/CD82 suppresses hepatocyte growth factor-induced migration of hepatoma cells via upregulation of Sprouty2.
Author: Mu, Zhenbin|Wang, Hua|Zhang, Jing|Li, Qingfang|Wang, Lisheng|Guo, Xiaozhong
PMID: 18622748
Journal: Cancer Lett. 2008 Dec 18;272(2):268-76.
Title: A novel and effective hepatocyte growth factor kringle 1 domain and p53 cocktail viral gene therapy for the treatment of hepatocellular carcinoma.
Author: Shen, Zan|Wong, Oscar Gee Wan|Yao, Ru Yong|Liang, Jun|Kung, Hsiang-Fu|Lin, Marie C M
PMID: 18722051
Journal: Biochem Soc Trans. 2008 Oct;36(Pt 5):848-52.
Title: S-adenosylmethionine and proliferation: new pathways, new targets.
Author: Martinez-Lopez, Nuria|Varela-Rey, Marta|Ariz, Usue|Embade, Nieves|Vazquez-Chantada, Mercedes|Fernandez-Ramos, David|Gomez-Santos, Laura|Lu, Shelly C|Mato, Jose M|Martinez-Chantar, Maria L
PMID: 18793149
Journal: Hepatogastroenterology. 2008 Jul-Aug;55(85):1439-44.
Title: Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis.
Author: Gotohda, Naoto|Iwagaki, Hiromi|Ozaki, Michitaka|Kinoshita, Taira|Konishi, Masaru|Nakagohri, Toshio|Takahashi, Shinichiro|Saito, Shinya|Yagi, Takahito|Tanaka, Noriaki
PMID: 18795707
Journal: Onkologie. 2008 Oct;31(10):550-5.
Title: Molecular pathogenesis and targeted therapy of hepatocellular carcinoma.
Author: Zender, Lars|Kubicka, Stefan
PMID: 18854656
Journal: J Cell Mol Med. 2009 Aug;13(8B):2673-83.
Title: Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Author: Huynh, Hung|Ngo, Van Chanh|Koong, Heng Nung|Poon, Donald|Choo, Su Pin|Thng, Choon Hua|Chow, Pierce|Ong, Hock Soo|Chung, Alexander|Soo, Khee Chee
PMID: 19220580
Journal: Magy Onkol. 2009 Mar;53(1):61-7.
Title: [Comparative genomic classification of human hepatocellular carcinoma].
Author: Kaposi-Novak, Pal
PMID: 19318328
Journal: Biochem Pharmacol. 2009 Jul 1;78(1):21-32.
Title: Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line.
Author: Mazzanti, Roberto|Platini, Francesca|Bottini, Consuelo|Fantappie, Ornella|Solazzo, Michela|Tessitore, Luciana
PMID: 19447220
Journal: J Proteome Res. 2010 Feb 5;9(2):798-805.
Title: Identification and confirmation of biomarkers using an integrated platform for quantitative analysis of glycoproteins and their glycosylations.
Author: Liu, Yashu|He, Jintang|Li, Chen|Benitez, Ricardo|Fu, Sherry|Marrero, Jorge|Lubman, David M
PMID: 19961239
Journal: Hepatology. 2010 Jan;51(1):255-66.
Title: Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression.
Author: Quiles-Perez, Rosa|Munoz-Gamez, Jose Antonio|Ruiz-Extremera, Angeles|O'Valle, Francisco|Sanjuan-Nunez, Laura|Martin-Alvarez, Ana Belen|Martin-Oliva, David|Caballero, Trinidad|Munoz de Rueda, Paloma|Leon, Josefa|Gonzalez, Raul|Muntane, Jordi|Oliver, Franci
PMID: 20034026
Journal: Exp Mol Pathol. 2010 Jun;88(3):331-40.
Title: The identification of stem cells in human liver diseases and hepatocellular carcinoma.
Author: Oliva, Joan|French, Barbara A|Qing, X|French, Samuel W
PMID: 20080086
Journal: Int J Oncol. 2010 May;36(5):1261-7.
Title: Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation.
Author: Grotegut, S|Kappler, R|Tarimoradi, S|Lehembre, F|Christofori, G|Von Schweinitz, D
PMID: 20372801
Journal: FEBS J. 2010 Dec;277(23):4888-900.
Title: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.
Author: Hashimoto, Tomio|Kato, Minoru|Shimomura, Takeshi|Kitamura, Naomi
PMID: 20977675
Journal: Biochem Biophys Res Commun. 2010 Dec 3;403(1):120-5.
Title: miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines.
Author: Henry, Jon C|Park, Jong-Kook|Jiang, Jinmai|Kim, Ji Hye|Nagorney, David M|Roberts, Lewis R|Banerjee, Soma|Schmittgen, Thomas D
PMID: 21055388
Journal: J Clin Invest. 2010 Dec;120(12):4493-506.
Title: Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
Author: Jung, Cho-Rok|Lim, Jung Hwa|Choi, Yoonjung|Kim, Dae-Ghon|Kang, Koo Jeong|Noh, Seung-Moo|Im, Dong-Soo
PMID: 21060154
Journal: Anticancer Res. 2011 Jan;31(1):339-44.
Title: Predictive value of serum biomarkers in patients after portal vein embolization (PVE): a pilot study.
Author: Treska, Vladislav|Topolcan, Ondrej|Vrzalova, Jindra|Skalicky, Tomas|Sutnar, Alan|Liska, Vaclav|Fichtl, Jakub|Narsanska, Andrea|Ferda, Jiri|Treskova, Inka|Mirka, Hyne|Kreuzberg, Boris
PMID: 21273621
Journal: Alcohol Clin Exp Res. 2011 May;35(5):821-5.
Title: Molecular pathogenesis of hepatocellular carcinoma.
Author: Cornella, Helena|Alsinet, Clara|Villanueva, Augusto
PMID: 21303380
Journal: FEBS Lett. 2011 Jul 21;585(14):2229-34.
Title: miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway.
Author: Tan, Sheng|Li, Rui|Ding, Keshuo|Lobie, Peter E|Zhu, Tao
PMID: 21658389
Journal: Biochem Biophys Res Commun. 2011 Jul 15;410(4):803-8.
Title: Regulation of human hepatocellular carcinoma cells by Spred2 and correlative studies on its mechanism.
Author: Ma, Xiao-Ni|Liu, Xiao-Yun|Yang, Yue-Feng|Xiao, Feng-Jun|Li, Qing-Fang|Yan, Jun|Zhang, Qun-Wei|Wang, Li-Sheng|Li, Xue-Yan|Wang, Hua
PMID: 21703232
Journal: PLoS One. 2011;6(8):e23311.
Title: Differences in the properties and mirna expression profiles between side populations from hepatic cancer cells and normal liver cells.
Author: Liu, Wei-hui|Tao, Kai-shan|You, Nan|Liu, Zheng-cai|Zhang, Hong-tao|Dou, Ke-feng
PMID: 21826246
Journal: Dig Dis. 2011;29(3):273-7.
Title: Molecular targeted therapy for hepatocellular carcinoma: bench to bedside.
Author: Kudo, Masatoshi
PMID: 21829017
Journal: J Radiat Res. 2011;52(5):582-91.
Title: Hepatic regeneration after sublethal partial liver irradiation in cirrhotic rats.
Author: Gu, Ke|Lai, Song-Tao|Ma, Ning-Yi|Zhao, Jian-Dong|Ren, Zhi-Gang|Wang, Jian|Liu, Jin|Jiang, Guo-Liang
PMID: 21952315
Journal: J Exp Clin Cancer Res. 2011 Oct 12;30:96.
Title: HGF/c-Met related activation of beta-catenin in hepatoblastoma.
Author: Purcell, Rachel|Childs, Margaret|Maibach, Rudolf|Miles, Carina|Turner, Clinton|Zimmermann, Arthur|Sullivan, Michael
PMID: 21992464
Journal: Hepatogastroenterology. 2012 Mar-Apr;59(114):551-7.
Title: Serum antithrombin III level is well correlated with multiple indicators for assessment of liver function and diagnostic accuracy for predicting postoperative liver failure in hepatocellular carcinoma patients.
Author: Mizuguchi, Toru|Kawamoto, Masaki|Meguro, Makoto|Son, Seiichi|Nakamura, Yukio|Harada, Kohei|Shibata, Toshihito|Ota, Shigenori|Hirata, Koichi
PMID: 22353523
Journal: J Surg Res. 2012 Nov;178(1):255-63.
Title: Liver hypertrophy and accelerated growth of implanted tumors in nonembolized liver of rabbit after left portal vein embolization.
Author: Zou, Ru-hai|Li, An-hua|Han, Feng|Hong, Jian|Li, Bin-kui|Huang, Wei|Huang, Liang|Yuan, Yun-fei
PMID: 22494913
Journal: Hepatology. 2012 Nov;56(5):1913-23.
Title: Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice.
Author: Hsu, Yu-Chen|Huang, Hsiang-Po|Yu, I-Shing|Su, Kang-Yi|Lin, Shu-Rung|Lin, Wei-Chou|Wu, Hua-Lin|Shi, Guey-Yueh|Tao, Mi-Hua|Kao, Cheng-Heng|Wu, Yao-Ming|Martin, Patricia E|Lin, Shih-Yao|Yang, Pan-Chyr|Lin, Shu-Wha
PMID: 22505209
Journal: Front Biosci (Schol Ed). 2012 Jun 1;4:1487-515.
Title: Growth factor pathways in development and progression of hepatocellular carcinoma.
Author: Nalesnik, Michael Andrew|Michalopoulos, George Konstantine
PMID: 22652888
Journal: PLoS One. 2012;7(6):e39771.
Title: beta-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice.
Author: Awuah, Prince Kwaku|Rhieu, Byung Han|Singh, Sucha|Misse, Amalea|Monga, Satdarshan P S
PMID: 22761897
Journal: Mol Cancer Res. 2012 Sep;10(9):1216-27.
Title: Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.
Author: Munoz, Ursula|Puche, Juan E|Hannivoort, Rebekka|Lang, Ursula E|Cohen-Naftaly, Michal|Friedman, Scott L
PMID: 22859706
Journal: Expert Rev Anticancer Ther. 2012 Oct;12(10):1347-57.
Title: Pathways and targets in hepatocellular carcinoma.
Author: Psyrri, Amanda|Arkadopoulos, Nikolaos|Vassilakopoulou, Maria|Smyrniotis, Vassilios|Dimitriadis, George
PMID: 23176622
Journal: Liver Cancer. 2012 Sep;1(2):83-93.
Title: Emerging signaling pathways in hepatocellular carcinoma.
Author: Moeini, Agrin|Cornella, Helena|Villanueva, Augusto
PMID: 24159576
Journal: Clin Cancer Res. 2013 May 1;19(9):2310-8.
Title: Targeting the HGF/c-MET pathway in hepatocellular carcinoma.
Author: Goyal, Lipika|Muzumdar, Mandar D|Zhu, Andrew X
PMID: 23388504
Journal: Phytomedicine. 2013 Jun 15;20(8-9):743-52.
Title: Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells.
Author: Shi, Ming-Der|Liao, Yi-Chen|Shih, Yuan-Wei|Tsai, Li-Yu
PMID: 23537747
Journal: J Cancer Res Clin Oncol. 2013 Jul;139(7):1169-78.
Title: Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Author: Chen, Qiang|Chen, Lei|Zhao, Ren|Yang, Xiao-dong|Imran, Khan|Xing, Chun-gen
PMID: 23563852
Journal: Mol Biol Rep. 2013 Jul;40(7):4203-9.
Title: Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo.
Author: Jiang, Hong-Lei|Jin, Jun-Zhe|Wu, Dan|Xu, Dong|Lin, Guo-Fu|Yu, Hao|Ma, Dong-Yan|Liang, Jian
PMID: 23649759
Journal: Mol Cell Biochem. 2013 Oct;382(1-2):83-92.
Title: Ganglioside GM3 promotes HGF-stimulated motility of murine hepatoma cell through enhanced phosphorylation of cMet at specific tyrosine sites and PI3K/Akt-mediated migration signaling.
Author: Li, Ying|Huang, Xiaohua|Zhong, Weiliang|Zhang, Jianing|Ma, Keli
PMID: 23749170
Journal: J Clin Invest. 2013 Jul;123(7):2780-3.
Title: Linking MLL and the HGF-MET signaling pathway in liver cancer.
Author: Marquardt, Jens U|Thorgeirsson, Snorri S
PMID: 23934122
Journal: J Clin Invest. 2013 Jul;123(7):3154-65.
Title: HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.
Author: Takeda, Shugaku|Liu, Han|Sasagawa, Satoru|Dong, Yiyu|Trainor, Paul A|Cheng, Emily H|Hsieh, James J
PMID: 23934123
Journal: Int J Biochem Cell Biol. 2013 Nov;45(11):2501-11.
Title: Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma.
Author: Castro-Sanchez, Luis|Agra, Noelia|Llorente Izquierdo, Cristina|Motino, Omar|Casado, Marta|Bosca, Lisardo|Martin-Sanz, Paloma
PMID: 23954207
Journal: PLoS One. 2013 Aug 20;8(8):e71273.
Title: Cell surface glycan alterations in epithelial mesenchymal transition process of Huh7 hepatocellular carcinoma cell.
Author: Li, Shan|Mo, Cuiju|Peng, Qiliu|Kang, Xiaonan|Sun, Chun|Jiang, Kai|Huang, Li|Lu, Yu|Sui, Jingzhe|Qin, Xue|Liu, Yinkun
PMID: 23977005
Journal: Clin Sci (Lond). 2014 Feb;126(3):243-52.
Title: Radiofrequency ablation suppresses distant tumour growth in a novel rat model of multifocal hepatocellular carcinoma.
Author: Eros de Bethlenfalva-Hora, Caroline|Mertens, Joachim C|Piguet, Anne-Christine|Kettenbach, Joachim|Schmitt, Johannes|Terracciano, Luigi|Weimann, Rosemarie|Dufour, Jean-Francois|Geier, Andreas
PMID: 23822114
Journal: J Hepatol. 2014 Feb;60(2):442-52.
Title: Met as a therapeutic target in HCC: facts and hopes.
Author: Giordano, Silvia|Columbano, Amedeo
PMID: 24045150
Journal: Invest New Drugs. 2014 Apr;32(2):355-61.
Title: A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second- or third-line therapy in the patients with metastatic gastric cancer.
Author: Kang, Yoon-Koo|Muro, Kei|Ryu, Min-Hee|Yasui, Hirofumi|Nishina, Tomohiro|Ryoo, Baek-Yeol|Kamiya, Yukimasa|Akinaga, Shiro|Boku, Narikazu
PMID: 24337769
Journal: Biochem Biophys Res Commun. 2014 Apr 4;446(2):541-8.
Title: Anti-miR-197 inhibits migration in HCC cells by targeting KAI 1/CD82.
Author: Dai, Weiqi|Wang, Chengfen|Wang, Fan|Wang, Yugang|Shen, Miao|Chen, Kan|Cheng, Ping|Zhang, Yan|Yang, Jing|Zhu, Rong|Zhang, Huawei|Li, Jingjing|Zheng, Yuanyuan|Lu, Jie|Zhou, Yingqun|Xu, Ling|Guo, Chuanyong
PMID: 24613834
Journal: Cancer Discov. 2014 Jun;4(6):730-43.
Title: Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.
Author: Horwitz, Elad|Stein, Ilan|Andreozzi, Mariacarla|Nemeth, Julia|Shoham, Avivit|Pappo, Orit|Schweitzer, Nora|Tornillo, Luigi|Kanarek, Naama|Quagliata, Luca|Zreik, Farid|Porat, Rinnat M|Finkelstein, Rutie|Reuter, Hendrik|Koschny, Ronald|Ganten, Tom|Mogler, Ca
PMID: 24687604
Journal: J Hepatol. 2014 Oct;61(4):883-90.
Title: Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice.
Author: Kroy, Daniela C|Schumacher, Fabienne|Ramadori, Pierluigi|Hatting, Maximilian|Bergheim, Ina|Gassler, Nikolaus|Boekschoten, Mark V|Muller, Michael|Streetz, Konrad L|Trautwein, Christian
PMID: 24845607
Journal: J Clin Invest. 2014 Jul;124(7):3172-86.
Title: Four individually druggable MET hotspots mediate HGF-driven tumor progression.
Author: Basilico, Cristina|Hultberg, Anna|Blanchetot, Christophe|de Jonge, Natalie|Festjens, Els|Hanssens, Valerie|Osepa, Sjudry-Ilona|De Boeck, Gitte|Mira, Alessia|Cazzanti, Manuela|Morello, Virginia|Dreier, Torsten|Saunders, Michael|de Haard, Hans|Michieli, Pao
PMID: 24865428
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jun;17(6):598-601.
Title: [Association of expression of HGF and its receptor c-Met to primary colorectal cancers with synchronous liver metastasis].
Author: Sun, Yanlai|Li, Zengjun|Xu, Zhongfa
PMID: 24953371
Journal: Indian J Clin Biochem. 2014 Jul;29(3):351-6.
Title: Evaluation of Apoptotic Marker Bcl2, CD4+, Human Hepatocyte Growth Factor and Metalloproteinase-9 as Tumor Markers for Patients with Hepatocellular Carcinoma.
Author: Youness, Eman R|El Nemr, Mohamed|Oraby, F S|Ahmed, Nadia M|Moghni, Mohamed A|Aly, Hanan F|Ahmed, Hanaa H
PMID: 24966485
Journal: Anticancer Agents Med Chem. 2014;14(9):1237-48.
Title: Antineoplastic activity of monocrotaline against hepatocellular carcinoma.
Author: Kusuma, Sandeep Solmon|Tanneeru, Karunakar|Didla, Swroopa|Devendra, Bellary Nagaraju|Kiranmayi, Patnala
PMID: 25028149
Journal: Biochem Biophys Res Commun. 2014 Aug 8;450(4):1304-12.
Title: MiR-181a-5p is downregulated in hepatocellular carcinoma and suppresses motility, invasion and branching-morphogenesis by directly targeting c-Met.
Author: Korhan, Peyda|Erdal, Esra|Atabey, Nese
PMID: 25058462
Journal: Liver Int. 2015 May;35(5):1590-6.
Title: Radioembolization of hepatocellular carcinoma activates liver regeneration, induces inflammation and endothelial stress and activates coagulation.
Author: Fernandez-Ros, Nerea|Inarrairaegui, Mercedes|Paramo, Jose A|Berasain, Carmen|Avila, Matias A|Chopitea, Ana|Varo, Nerea|Sarobe, Pablo|Bilbao, Jose I|Dominguez, Ines|D'Avola, Delia|Herrero, J Ignacio|Quiroga, Jorge|Sangro, Bruno
PMID: 24836705
Journal: Toxicol Lett. 2015 Jan 22;232(2):499-512.
Title: Leishmanial lipid affords protection against oxidative stress induced hepatic injury by regulating inflammatory mediators and confining apoptosis progress.
Author: Chatterjee, Nabanita|Das, Subhadip|Bose, Dipayan|Banerjee, Somenath|Jha, Tarun|Saha, Krishna Das
PMID: 25445725
Journal: PLoS One. 2015 Jan 21;10(1):e0114495.
Title: Preclinical trials for prevention of tumor progression of hepatocellular carcinoma by LZ-8 targeting c-Met dependent and independent pathways.
Author: Wu, Jia-Ru|Hu, Chi-Tan|You, Ren-In|Ma, Pei-Ling|Pan, Siou-Mei|Lee, Ming-Che|Wu, Wen-Sheng
PMID: 25607934
Journal: Sci Rep. 2015 Jan 26;5:8021.
Title: Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells.
Author: Garcia-Vilas, Javier A|Quesada, Ana R|Medina, Miguel A
PMID: 25620570
Journal: Cell Physiol Biochem. 2015;35(3):983-96.
Title: MACC1 suppresses cell apoptosis in hepatocellular carcinoma by targeting the HGF/c-MET/AKT pathway.
Author: Yao, Yingmin|Dou, Chanwei|Lu, Zhongtang|Zheng, Xin|Liu, Qingguang
PMID: 25660117
Journal: Oncogene. 2015 Nov 12;34(46):5718-28.
Title: Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.
Author: Gui, Y|Yeganeh, M|Donates, Y-C|Tobelaim, W-S|Chababi, W|Mayhue, M|Yoshimura, A|Ramanathan, S|Saucier, C|Ilangumaran, S
PMID: 25728680
Journal: Anticancer Res. 2015 Apr;35(4):2021-8.
Title: Gene expression analysis for evaluation of potential biomarkers in hepatocellular carcinoma.
Author: Hass, Holger G|Jobst, Juergen|Scheurlen, Michael|Vogel, Ulrich|Nehls, Oliver
PMID: 25862856
Journal: Cancer Gene Ther. 2015 May;22(5):262-70.
Title: Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines.
Author: Hung, T-H|Li, Y-H|Tseng, C-P|Lan, Y-W|Hsu, S-C|Chen, Y-H|Huang, T-T|Lai, H-C|Chen, C-M|Choo, K-B|Chong, K-Y
PMID: 25908454
Journal: Oncotarget. 2015 Oct 20;6(32):32526-44.
Title: Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression.
Author: Wu, Jia-Ru|Hu, Chi-Tan|You, Ren-In|Pan, Siou-Mei|Cheng, Chuan-Chu|Lee, Ming-Che|Wu, Chao-Chuan|Chang, Yao-Jen|Lin, Shu-Chuan|Chen, Chang-Shan|Lin, Teng-Yi|Wu, Wen-Sheng
PMID: 26416447
Journal: J Exp Clin Cancer Res. 2015 Oct 12;34:118.
Title: Tivantinib induces G2/M arrest and apoptosis by disrupting tubulin polymerization in hepatocellular carcinoma.
Author: Xiang, Qingfeng|Zhen, Zuojun|Deng, David Yb|Wang, Jingnan|Chen, Yingjun|Li, Jieyuan|Zhang, Yingfei|Wang, Fengjie|Chen, Ningning|Chen, Huanwei|Chen, Yajin
PMID: 26458953
Journal: Oncotarget. 2015 Dec 15;6(40):42923-37.
Title: Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer.
Author: Chen, Wei-Ching|Chang, Yung-Sheng|Hsu, Hui-Ping|Yen, Meng-Chi|Huang, Hau-Lun|Cho, Chien-Yu|Wang, Chih-Yang|Weng, Tzu-Yang|Lai, Po-Ting|Chen, Ching-Shih|Lin, Yih-Jyh|Lai, Ming-Derg
PMID: 26556861
Journal: J Hepatocell Carcinoma. 2015 Apr 24;2:29-38.
Title: c-MET receptor tyrosine kinase as a molecular target in advanced hepatocellular carcinoma.
Author: Granito, Alessandro|Guidetti, Elena|Gramantieri, Laura
PMID: 27508192
Journal: Tumour Biol. 2016 Jun;37(6):7741-8.
Title: SENP1 regulates hepatocyte growth factor-induced migration and epithelial-mesenchymal transition of hepatocellular carcinoma.
Author: Zhang, Wenwen|Sun, Huiyan|Shi, Xuefeng|Wang, Hua|Cui, Chunping|Xiao, Fengjun|Wu, ChuTse|Guo, Xiaozhong|Wang, Lisheng
PMID: 26695141
Journal: Oncotarget. 2016 Mar 8;7(10):11067-82.
Title: Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2.
Author: Lin, Chung-Yi|Hu, Chi-Tan|Cheng, Chuan-Chu|Lee, Ming-Che|Pan, Siou-Mei|Lin, Teng-Yi|Wu, Wen-Sheng
PMID: 26840563
Journal: Future Oncol. 2016 May;12(10):1275-86.
Title: Trends in the development of MET inhibitors for hepatocellular carcinoma.
Author: Okuma, Hitomi S|Kondo, Shunsuke
PMID: 26984595
Journal: Cell Rep. 2016 May 10;15(6):1175-89.
Title: Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling.
Author: Lau, Eunice Yuen Ting|Lo, Jessica|Cheng, Bowie Yik Ling|Ma, Mark Kin Fai|Lee, Joyce Man Fong|Ng, Johnson Kai Yu|Chai, Stella|Lin, Chi Ho|Tsang, Suk Ying|Ma, Stephanie|Ng, Irene Oi Lin|Lee, Terence Kin Wah
PMID: 27134167
Journal: Oncotarget. 2016 Jun 21;7(25):38292-38305.
Title: Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma.
Author: Deng, Yan-Ru|Liu, Wen-Bin|Lian, Zhe-Xiong|Li, Xingsheng|Hou, Xin
PMID: 27203677
Journal: Clin Cancer Res. 2016 Oct 1;22(19):4870-4879.
Title: Biomarker Analyses of Clinical Outcomes in Patients with Advanced Hepatocellular Carcinoma Treated with Sorafenib with or without Erlotinib in the SEARCH Trial.
Author: Zhu, Andrew X|Kang, Yoon-Koo|Rosmorduc, Olivier|Evans, T R Jeffry|Santoro, Armando|Ross, Paul|Gane, Edward|Vogel, Arndt|Jeffers, Michael|Meinhardt, Gerold|Pena, Carol E A
PMID: 27220960
Journal: Eur Rev Med Pharmacol Sci. 2016 Jul;20(15):3186-93.
Title: The effect of sequential transcatheter arterial chemoembolization (TACE) and portal venous embolizations (PVE) vs. TACE or PVE alone on rabbit VX2 liver carcinoma and on liver regeneration.
Author: Guo, W-C|He, X-F|Li, Y-H|Li, Z-H|Mei, Q-L|Chen, Y
PMID: 27466990
Journal: J Agric Food Chem. 2016 Sep 21;64(37):7002-13.
Title: Repression of Human Hepatocellular Carcinoma Growth by Regulating Met/EGFR/VEGFR-Akt/NF-kappaB Pathways with Theanine and Its Derivative, (R)-2-(6,8-Dibromo-2-oxo-2H-chromene-3-carboxamido)-5-(ethylamino)-5-oxopentanoic Ethyl Ester (DTBrC).
Author: Zhang, Guoying|Li, Zheng|Wan, Xiaochun|Zhang, Ying|Zhu, Rongqin|Liu, Zhenzhen|Ji, Dexin|Zhang, Huarong|Wu, Fei|Tian, Huihui|Liu, Kun|Wu, Benhao
PMID: 27569455
Journal: J Exp Clin Cancer Res. 2016 Sep 30;35(1):159.
Title: Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro.
Author: Qu, Zhen|Wu, Junhua|Wu, Junyi|Luo, Dongjun|Jiang, Chunping|Ding, Yitao
PMID: 27716356
Journal: Oncoimmunology. 2016 Sep 27;5(10):e1219828.
Title: Peritumoral stromal neutrophils are essential for c-Met-elicited metastasis in human hepatocellular carcinoma.
Author: He, Min|Peng, Anping|Huang, Xian-Zhang|Shi, Dai-Chao|Wang, Jun-Cheng|Zhao, Qiyi|Lin, Haibiao|Kuang, Dong-Ming|Ke, Pei-Feng|Lao, Xiang-Ming
PMID: 27853643
Journal: Curr Pharm Des. 2017;23(1):170-175.
Title: Targeting Signalling Pathways in Hepatocellular Carcinoma.
Author: Blagotinsek, Kaja|Rozman, Damjana
PMID: 27719638
Journal: Oncol Rep. 2017 Feb;37(2):1203-1211.
Title: Resveratrol suppresses human hepatocellular carcinoma via targeting HGF-c-Met signaling pathway.
Author: Gao, Feng|Deng, Gang|Liu, Wenbin|Zhou, Kechao|Li, Ming
PMID: 28075467
Journal: Onco Targets Ther. 2017 Feb 14;10:847-857.
Title: Correlations of microvascular blood flow of contrast-enhanced ultrasound and HGF/c-Met signaling pathway with clinicopathological features and prognosis of patients with hepatocellular carcinoma.
Author: Zhuang, Peng-Hui|Xu, Lei|Gao, Lu|Lu, Wei|Ruan, Li-Tao|Yang, Jin
PMID: 28243120
Journal: Cell Death Dis. 2017 Mar 30;8(3):e2706.
Title: MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2.
Author: Ghosh, Alip|Dasgupta, Debanjali|Ghosh, Amit|Roychoudhury, Shrabasti|Kumar, Dhiraj|Gorain, Mahadeo|Butti, Ramesh|Datta, Simanti|Agarwal, Shaleen|Gupta, Subash|Krishna Dhali, Gopal|Chowdhury, Abhijit|Schmittgen, Thomas D|Kundu, Gopal C|Banerjee, Soma
PMID: 28358369
Journal: Cancer Lett. 2017 Sep 28;404:19-28.
Title: Peri-tumor associated fibroblasts promote intrahepatic metastasis of hepatocellular carcinoma by recruiting cancer stem cells.
Author: Jiang, Jinghua|Ye, Fei|Yang, Xue|Zong, Chen|Gao, Lu|Yang, Yang|Zhao, Qiudong|Han, Zhipeng|Wei, Lixin
PMID: 28716525
Journal: Sci Rep. 2017 Nov 17;7(1):15812.
Title: Therapeutic effects of hepatocyte growth factor-overexpressing dental pulp stem cells on liver cirrhosis in a rat model.
Author: Cao, Xiao-Fang|Jin, Shi-Zhu|Sun, Liang|Zhan, Yuan-Bo|Lin, Feng|Li, Ying|Zhou, Ying-Lian|Wang, Xiu-Mei|Gao, Li|Zhang, Bin
PMID: 29150644
Journal: BMC Cancer. 2017 Dec 19;17(1):870.
Title: Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study.
Author: Hayashi, Tomoyuki|Yamashita, Taro|Terashima, Takeshi|Suda, Tsuyoshi|Okada, Hikari|Asahina, Yoshiro|Hayashi, Takehiro|Hara, Yasumasa|Nio, Kouki|Sunagozaka, Hajime|Takatori, Hajime|Arai, Kuniaki|Sakai, Yoshio|Yamashita, Tatsuya|Mizukoshi, Eishiro|Honda, Mas
PMID: 29258450
Journal: Int J Hyperthermia. 2018 Sep;34(6):812-823.
Title: Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma.
Author: Thompson, Scott M|Jondal, Danielle E|Butters, Kim A|Knudsen, Bruce E|Anderson, Jill L|Stokes, Matthew P|Jia, Xiaoying|Grande, Joseph P|Roberts, Lewis R|Callstrom, Matthew R|Woodrum, David A
PMID: 28954551
Journal: Matrix Biol. 2018 Mar;66:81-92.
Title: Deficiency of periostin impairs liver regeneration in mice after partial hepatectomy.
Author: Wu, Tiantian|Huang, Jingwen|Wu, Shasha|Huang, Zhengjie|Chen, Xiaoyan|Liu, Yingfu|Cui, Dan|Song, Gang|Luo, Qi|Liu, Fan|Ouyang, Gaoliang
PMID: 28965986
Journal: Life Sci. 2018 Jan 1;192:91-98.
Title: Splenectomy after partial hepatectomy accelerates liver regeneration in mice by promoting tight junction formation via polarity protein Par 3-aPKC.
Author: Liu, Guoxing|Xie, Chengzhi|Fang, Yu|Qian, Ke|Liu, Qiang|Liu, Gao|Cao, Zhenyu|Du, Huihui|Fu, Jie|Xu, Xundi
PMID: 29166570
Journal: World J Gastroenterol. 2018 Jan 14;24(2):237-247.
Title: Transplantation of bone marrow-derived endothelial progenitor cells and hepatocyte stem cells from liver fibrosis rats ameliorates liver fibrosis.
Author: Lan, Ling|Liu, Ran|Qin, Ling-Yun|Cheng, Peng|Liu, Bo-Wei|Zhang, Bing-Yong|Ding, Song-Ze|Li, Xiu-Ling
PMID: 29375209
Journal: World J Gastroenterol. 2018 Jan 21;24(3):371-378.
Title: Multi-parameter gene expression profiling of peripheral blood for early detection of hepatocellular carcinoma.
Author: Xie, Hui|Xue, Yao-Qin|Liu, Peng|Zhang, Peng-Jun|Tian, Sheng-Tao|Yang, Zhao|Guo, Zhi|Wang, Hua-Ming
PMID: 29391759
Journal: Oncotarget. 2017 Oct 26;9(1):152-166.
Title: Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway.
Author: Li, Ming|Yu, Xinfang|Li, Wei|Liu, Ting|Deng, Gang|Liu, Wenbin|Liu, Haidan|Gao, Feng
PMID: 29416603
Journal: J Exp Clin Cancer Res. 2018 Apr 30;37(1):93.
Title: The dual blockade of MET and VEGFR2 signaling demonstrates pronounced inhibition on tumor growth and metastasis of hepatocellular carcinoma.
Author: Zhang, Yu|Gao, Xiaomei|Zhu, Ying|Kadel, Dhruba|Sun, Haoran|Chen, Jing|Luo, Qin|Sun, Haoting|Yang, Luyu|Yang, Jing|Sheng, Yuanyuan|Zheng, Yan|Zhu, Kejin|Dong, Qiongzhu|Qin, Lunxiu
PMID: 29712569
Journal: Hepatobiliary Pancreat Dis Int. 2018 Aug;17(4):336-344.
Title: MicroRNA-449a suppresses hepatocellular carcinoma cell growth via G1 phase arrest and the HGF/MET c-Met pathway.
Author: Cheng, Jun|Wu, Li-Ming|Deng, Xue-Song|Wu, Jian|Lv, Zhen|Zhao, Hang-Fen|Yang, Zhang|Ni, Yong
PMID: 30108016
Journal: Biomed Pharmacother. 2018 Sep 11;108:65-75.
Title: Chemopreventive and antitumor effects of benzyl isothiocynate on HCC models: A possible role of HGF /pAkt/ STAT3 axis and VEGF.
Author: Zakaria, Sherin|Helmy, Maged Wasfy|Salahuddin, Ahmed|Omran, Gamal
PMID: 30216802
Journal: Life Sci. 2018 Oct 4. pii: S0024-3205(18)30619-2.
Title: Inhibition of SRC/FAK cue: A novel pathway for the synergistic effect of rosuvastatin on the anti-cancer effect of dasatinib in hepatocellular carcinoma.
Author: El Sayed, Ibrahim|Helmy, Maged W|El-Abhar, Hanan S
PMID: 30292831