Primary Site >> Stomach Cancer

Gene >> HGF

Journal: J Biol Chem. 1991 Oct 15;266(29):19558-64.
Title: Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase.
Author: Ferracini, R|Longati, P|Naldini, L|Vigna, E|Comoglio, P M
PMID: 1655790
Journal: FEBS Lett. 1993 Nov 22;334(3):331-4.
Title: Stimulation of prostaglandin production by hepatocyte growth factor in human gastric carcinoma cells.
Author: Hori, T|Shibamoto, S|Hayakawa, M|Takeuchi, K|Oku, N|Miyazawa, K|Kitamura, N|Ito, F
PMID: 8243642
Journal: Int J Oncol. 1993 Dec;3(6):1067-70.
Title: Expression of hepatocyte growth factor(hgf) and C-met gene in human gastric-cancer cell-lines.
Author: Fushida, S|Yonemura, Y|Urano, T|Yamaguchi, A|Miyazaki, I|Nakamura, T|Shiku, H
PMID: 21573474
Journal: Int J Oncol. 1993 Jul;3(1):89-93.
Title: Biologic effect of human hepatocyte growth-factor on human gastric-carcinoma cell-lines.
Author: Yokozaki, H|Ito, M|Yasui, W|Kyo, E|Kuniyasu, H|Kitadai, Y|Tsubouchi, H|Daikuhara, Y|Tahara, E
PMID: 21573331
Journal: Int J Oncol. 1993 Aug;3(2):265-71.
Title: Reduced tumorigenicity and cell motility of a gastric-carcinoma cell-line by introduction of wild-type p53 gene.
Author: Kyo, E|Yokozaki, H|Yanagihara, K|Yasui, W|Ito, M|Sano, T|Lee, P|Saya, H|Tahara, E
PMID: 21573358
Journal: Gan To Kagaku Ryoho. 1994 Nov;21(15):2541-8.
Title: [Metastasis-related genes].
Author: Yokozaki, H|Tahara, E
PMID: 7526801
Journal: Gan To Kagaku Ryoho. 1994 Oct;21(14):2371-7.
Title: [Genetic characteristics of scirrhous gastric carcinomas].
Author: Yokozaki, H|Kuniyasu, H|Yasui, W|Tahara, E
PMID: 7944479
Journal: Virchows Arch. 1994;425(2):139-44.
Title: Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines.
Author: Tannapfel, A|Yasui, W|Yokozaki, H|Wittekind, C|Tahara, E
PMID: 7952499
Journal: Princess Takamatsu Symp. 1994;24:187-94.
Title: Cancer-stromal interaction through growth factor/cytokine networks implicated in growth of stomach cancer.
Author: Tahara, E
PMID: 8983075
Journal: Dig Dis Sci. 1995 May;40(5):1132-9.
Title: Roles of hepatocyte growth factor and its receptor in gastric mucosa. A cell biological and molecular biological study.
Author: Tsuji, S|Kawano, S|Tsujii, M|Fusamoto, H|Kamada, T
PMID: 7729276
Journal: Eur J Biochem. 1996 Mar 1;236(2):476-81.
Title: Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells.
Author: Nagamine, K|Shibamoto, S|Takeuchi, K|Miyazawa, K|Kitamura, N|Chatani, Y|Kohno, M|Ito, F
PMID: 8612619
Journal: Nihon Geka Gakkai Zasshi. 1996 Apr;97(4):252-6.
Title: [Genetic alterations in stomach cancer].
Author: Tahara, E|Yasui, W|Yokozaki, H
PMID: 8692139
Journal: Oncol Rep. 1996 May;3(3):425-8.
Title: A splice variant of the c-met proto-oncogene is the predominant population expressed in human gastric mucosa and carcinoma.
Author: Yokozaki, H|Semba, S|Yamamoto, S|Tahara, E
PMID: 21594385
Journal: Anticancer Res. 1997 Sep-Oct;17(5A):3575-80.
Title: Effect of hepatocyte growth factor on cell cycle and c-met expression in human gastric cancer cells.
Author: Liu, S I|Lui, W Y|Mok, K T|Wu, C W|Chi, C W
PMID: 9413205
Journal: Oncol Rep. 1997 Nov-Dec;4(6):1239-41.
Title: Increased concentration of hepatocyte growth factor in the sera of patients with gastrointestinal cancer.
Author: Narita, T|Mitsuoka, C|Kimura, N|Toi, M|Nakashio, T|Sekiguchi, K|Iwanari, H|Kannagi, R
PMID: 21590229
Journal: Biochim Biophys Acta. 1998 Jan 19;1368(2):256-66.
Title: Correlation of hepatocyte growth factor-induced proliferation and calcium-activated potassium current in human gastric cancer cells.
Author: Liu, S I|Chi, C W|Lui, W Y|Mok, K T|Wu, C W|Wu, S N
PMID: 9459603
Journal: Anticancer Res. 1998 Sep-Oct;18(5B):3657-9.
Title: Serum hepatocyte growth factor level associate with gastric cancer progression.
Author: Wu, C W|Chi, C W|Su, T L|Liu, T Y|Lui, W Y|P'eng, F K
PMID: 9854473
Journal: Hepatogastroenterology. 1998 Nov-Dec;45(24):2458-63.
Title: Serum human hepatocyte growth factor (hHGF) is elevated in patients with metastatic gastric carcinoma.
Author: Niki, M|Isozaki, H|Toyoda, M|Ishibashi, T|Fujii, K|Nomura, E|Mabuchi, H|Nakamura, M|Nishiguchi, K|Tanigawa, N
PMID: 9951944
Journal: Hepatogastroenterology. 1999 Jan-Feb;46(25):568-73.
Title: Serum human hepatocyte growth factor (hHGF) is elevated in patients with metastatic gastric carcinoma.
Author: Niki, M|Isozaki, H|Toyoda, M|Ishibashi, T|Fujii, K|Nomura, E|Mabuchi, H|Nakamura, M|Nishiguchi, K|Tanigawa, N
PMID: 10228863
Journal: World J Surg. 1999 Nov;23(11):1176-80.
Title: Significant correlation between serum level of hepatocyte growth factor and progression of gastric carcinoma.
Author: Han, S U|Lee, J H|Kim, W H|Cho, Y K|Kim, M W
PMID: 10501881
Journal: Oncogene. 2000 Oct 12;19(43):4947-53.
Title: A novel germ line juxtamembrane Met mutation in human gastric cancer.
Author: Lee, J H|Han, S U|Cho, H|Jennings, B|Gerrard, B|Dean, M|Schmidt, L|Zbar, B|Vande Woude, G F
PMID: 11042681
Journal: Am J Physiol Gastrointest Liver Physiol. 2000 Apr;278(4):G635-43.
Title: Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa.
Author: Itoh, H|Kataoka, H|Tomita, M|Hamasuna, R|Nawa, Y|Kitamura, N|Koono, M
PMID: 10762618
Journal: Anticancer Res. 2000 Mar-Apr;20(2B):1263-7.
Title: Elevation of serum hepatocyte growth factor concentration in patients with gastric cancer is mediated by production from tumor tissue.
Author: Beppu, K|Uchiyama, A|Morisaki, T|Nakamura, K|Noshiro, H|Matsumoto, K|Nakamura, T|Tanaka, M|Katano, M
PMID: 10810432
Journal: Oncogene. 2002 Jul 25;21(32):4885-93.
Title: K252a inhibits the oncogenic properties of Met, the HGF receptor.
Author: Morotti, Alessandro|Mila, Silvia|Accornero, Paolo|Tagliabue, Emma|Ponzetto, Carola
PMID: 12118367
Journal: Cancer Gene Ther. 2002 Aug;9(8):700-7.
Title: Tumor suppression effect using NK4, a molecule acting as an antagonist of HGF, on human gastric carcinomas.
Author: Hirao, Shuya|Yamada, Yukishige|Koyama, Fumikazu|Fujimoto, Heisuke|Takahama, Yasushi|Ueno, Masato|Kamada, Kiyoshi|Mizuno, Takashi|Maemondo, Makoto|Nukiwa, Toshihiro|Matsumoto, Kunio|Nakamura, Toshikazu|Nakajima, Yoshiyuki
PMID: 12136432
Journal: J Physiol Pharmacol. 2003 Mar;54(1):17-32.
Title: Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells.
Author: Konturek, P C|Kania, J|Kukharsky, V|Ocker, S|Hahn, E G|Konturek, S J
PMID: 12674216
Journal: J Gene Med. 2004 Mar;6(3):317-27.
Title: Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.
Author: Heideman, Danielle A M|van Beusechem, Victor W|Bloemena, Elisabeth|Snijders, Peter J F|Craanen, Mikael E|Offerhaus, G Johan A|Derksen, Patrick W B|de Bruin, Michiel|Witlox, M Adhiambo|Molenaar, Bonnie|Meijer, Chris J L M|Gerritsen, Winald R
PMID: 15026993
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:158-64.
Title: Helicobacter pylori eradication treatment modulates epithelial cell proliferation and tissue content of hepatocyte growth factor in the gastric mucosa.
Author: Suzuki, M|Suzuki, H|Masaoka, T|Tanaka, S|Suzuki, K|Ishii, H
PMID: 15298622
Journal: Eur J Cancer. 2004 Sep;40(14):2135-42.
Title: Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
Author: Ueda, Kentaro|Iwahashi, Makoto|Matsuura, Ichiro|Nakamori, Mikihito|Nakamura, Masaki|Ojima, Toshiyasu|Naka, Teiji|Ishida, Koichiro|Matsumoto, Kunio|Nakamura, Toshikazu|Yamaue, Hiroki
PMID: 15341989
Journal: Exp Cell Res. 2004 Dec 10;301(2):168-78.
Title: Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.
Author: Shida, Dai|Kitayama, Joji|Yamaguchi, Hironori|Hama, Kotaro|Aoki, Junken|Arai, Hiroyuki|Yamashita, Hiroharu|Mori, Ken|Sako, Akihiro|Konishi, Tsuyoshi|Watanabe, Toshiaki|Sakai, Teruyuki|Suzuki, Rika|Ohta, Hideo|Takuwa, Yoh|Nagawa, Hirokazu
PMID: 15530853
Journal: Dig Dis Sci. 2005 Oct;50 Suppl 1:S3-S11.
Title: 15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications.
Author: Arakawa, Tetsuo|Higuchi, Kazuhide|Fujiwara, Yasuhiro|Watanabe, Toshio|Tominaga, Kazunari|Sasaki, Eiji|Oshitani, Nobuhide|Yoshikawa, Toshikazu|Tarnawski, Andrzej S
PMID: 16184418
Journal: Ann Surg. 2005 Nov;242(5):676-83.
Title: Modulation of E-cadherin by hepatocyte growth factor induces aggressiveness of gastric carcinoma.
Author: Han, Sang-Uk|Lee, Hwa-Young|Lee, Jae-Ho|Kim, Wook-Hwan|Nam, Hyunja|Kim, Hong|Cho, Yong-Kwan|Kim, Myung-Wook|Lee, Kuhn Uk
PMID: 16244541
Journal: Gastric Cancer. 2005;8(2):124-31.
Title: Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: role of IL-6 as a prognostic factor.
Author: Ashizawa, Tatsuto|Okada, Ryosuke|Suzuki, Yoshiaki|Takagi, Makoto|Yamazaki, Tatsuyuki|Sumi, Tetsuo|Aoki, Toshiaki|Ohnuma, Shinobu|Aoki, Tatsuya
PMID: 15864720
Journal: Int J Cancer. 2006 Mar 15;118(6):1545-55.
Title: Preclinical study of a "tailor-made" combination of NK4-expressing gene therapy and gefitinib (ZD1839, Iressa) for disseminated peritoneal scirrhous gastric cancer.
Author: Namiki, Yoshihisa|Namiki, Tamami|Yoshida, Hiroshi|Date, Masataka|Yashiro, Masakazu|Matsumoto, Kunio|Nakamura, Toshikazu|Yanagihara, Kazuyoshi|Tada, Norio|Satoi, Jujin|Fujise, Kiyotaka
PMID: 16206271
Journal: Cancer Lett. 2006 Aug 8;239(2):263-70. Epub 2005 Oct 21.
Title: Effects of COX-2 inhibitor on growth of human gastric cancer cells and its relation to hepatocyte growth factor.
Author: Chen, Jen-Hao|Wu, Chew-Wun|Kao, Hwa-Li|Chang, Hwey-May|Li, Anna F-Y|Liu, Tsung-Yun|Chi, Chin-Wen
PMID: 16243430
Journal: Korean J Intern Med. 2006 Mar;21(1):20-7.
Title: Hepatocyte growth factor/c-met signaling in regulating urokinase plasminogen activator in human stomach cancer: A potential therapeutic target for human stomach cancer.
Author: Lee, Kyung Hee|Choi, Eun Young|Hyun, Myung Soo|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong
PMID: 16646560
Journal: Oral Oncol. 2007 Nov;43(10):1021-5. Epub 2007 Feb 15.
Title: Serum hepatocyte growth factor as a marker of tumor activity in head and neck squamous cell carcinoma.
Author: Kim, Chul-Ho|Lee, Jin Seok|Kang, Sung-Ook|Bae, Joon-Ho|Hong, Sung Pyo|Kahng, Hison
PMID: 17306605
Journal: Eur Surg Res. 2007;39(4):208-15. Epub 2007 Mar 30.
Title: Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells.
Author: Lee, K H|Choi, E Y|Hyun, M S|Jang, B I|Kim, T N|Kim, S W|Song, S K|Kim, J H|Kim, J-R
PMID: 17396032
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Nov;27(11):1771-3.
Title: [Expression of hepatocyte growth factor and its receptor in gastric cancer].
Author: Chen, Jun-zhong|Zhao, Yong|Xu, Jia-feng|Liu, Qing|Liu, Sheng-huo|Zhang, Hong-de
PMID: 18024311
Journal: Oncol Res. 2008;17(1):23-32.
Title: Hepatocyte growth factor promotes cell survival by phosphorylation of BAD in gastric cancer cells.
Author: Lee, Kyung Hee|Choi, Eun Young|Kim, Min Kyoung|Hyun, Myung Soo|Eun, Jong Ryul|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong
PMID: 18488712
Journal: Bratisl Lek Listy. 2009;110(10):627-9.
Title: Increase in the circulating level of hepatocyte growth factor in pancreatic cancer patients.
Author: Kemik, Ozgur|Purisa, Sevim|Kemik, Ahu Sarbay|Tuzun, Sefa
PMID: 20017454
Journal: Pathol Oncol Res. 2009 Dec;15(4):589-96.
Title: Prognostic value of tumor-related molecular expression in gastric carcinoma.
Author: Zhao, Zhong-Sheng|Wang, Yuan-Yu|Ye, Zai-Yuan|Tao, Hou-Quan
PMID: 19294533
Journal: Hepatogastroenterology. 2009 May-Jun;56(91-92):891-8.
Title: Molecular characterization and significance for prognosis of free gastric cancer cells in the peritoneal cavity.
Author: Li, Chunfeng|Ma, Yan|Xue, Yingwei|Zhang, Hongfeng|Wei, Yuzhe
PMID: 19621724
Journal: Histol Histopathol. 2010 Jan;25(1):63-72.
Title: Expression of Reg IV and Hath1 in neuroendocrine neoplasms.
Author: Heiskala, Kukka|Arola, Johanna|Heiskala, Marja|Andersson, Leif C
PMID: 19924642
Journal: J Clin Invest. 2010 Dec;120(12):4493-506.
Title: Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
Author: Jung, Cho-Rok|Lim, Jung Hwa|Choi, Yoonjung|Kim, Dae-Ghon|Kang, Koo Jeong|Noh, Seung-Moo|Im, Dong-Soo
PMID: 21060154
Journal: J Clin Oncol. 2011 Dec 20;29(36):4789-95.
Title: Genetic activation of the MET pathway and prognosis of patients with high-risk, radically resected gastric cancer.
Author: Graziano, Francesco|Galluccio, Nadia|Lorenzini, Paola|Ruzzo, Annamaria|Canestrari, Emanuele|D'Emidio, Silvia|Catalano, Vincenzo|Sisti, Valerio|Ligorio, Claudia|Andreoni, Francesca|Rulli, Eliana|Di Oto, Enrico|Fiorentini, Giammaria|Zingaretti, Costantino|D
PMID: 22042954
Journal: Kurume Med J. 2011;58(3):73-9.
Title: Comparison between the gastric cancer cell line MKN-45 and the high-potential peritoneal dissemination gastric cancer cell line MKN-45P.
Author: Koga, Atsuhiko|Aoyagi, Keishiro|Imaizumi, Takuya|Miyagi, Motoshi|Shirouzu, Kazuo
PMID: 22531121
Journal: Cancer Discov. 2011 Dec;1(7):550-4.
Title: Anti-MET targeted therapy has come of age: the first durable complete response with MetMAb in metastatic gastric cancer.
Author: Feng, Yan|Ma, Patrick C
PMID: 22586678
Journal: Cancer Lett. 2012 Jun 1;319(1):109-17.
Title: c-Met upregulates aquaporin 3 expression in human gastric carcinoma cells via the ERK signalling pathway.
Author: Wang, Jianping|Gui, Zhifu|Deng, Longying|Sun, Maocai|Guo, Renhua|Zhang, Weiming|Shen, Lizong
PMID: 22261330
Journal: J Clin Invest. 2012 Mar;122(3):923-34.
Title: Essential role of gastric gland mucin in preventing gastric cancer in mice.
Author: Karasawa, Fumitoshi|Shiota, Akira|Goso, Yukinobu|Kobayashi, Motohiro|Sato, Yoshiko|Masumoto, Junya|Fujiwara, Maiko|Yokosawa, Shuichi|Muraki, Takashi|Miyagawa, Shinichi|Ueda, Masatsugu|Fukuda, Michiko N|Fukuda, Minoru|Ishihara, Kazuhiko|Nakayama, Jun
PMID: 22307328
Journal: Curr Treat Options Oncol. 2012 Sep;13(3):377-89.
Title: Targeted therapy for gastric cancer.
Author: Smyth, Elizabeth C|Cunningham, David
PMID: 22552927
Journal: Bioorg Med Chem Lett. 2012 Jul 15;22(14):4693-6.
Title: 'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.
Author: Colombo, Francesco|Tintori, Cristina|Furlan, Alessandro|Borrelli, Stella|Christodoulou, Michael S|Dono, Rosanna|Maina, Flavio|Botta, Maurizio|Amat, Mercedes|Bosch, Joan|Passarella, Daniele
PMID: 22738633
Journal: Carcinogenesis. 2013 Sep;34(9):2156-69.
Title: SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities.
Author: Hong, Sang-Won|Jung, Kyung Hee|Lee, Hee-Seung|Son, Mi Kwon|Yan, Hong Hua|Kang, Nam Sook|Lee, Jongkook|Hong, Soon-Sun
PMID: 23671132
Journal: J Pathol. 2013 Nov;231(3):301-10.
Title: The genomic landscape of oesophagogastric junctional adenocarcinoma.
Author: Chong, Irene Y|Cunningham, David|Barber, Louise J|Campbell, James|Chen, Lina|Kozarewa, Iwanka|Fenwick, Kerry|Assiotis, Ioannis|Guettler, Sebastian|Garcia-Murillas, Isaac|Awan, Saima|Lambros, Maryou|Starling, Naureen|Wotherspoon, Andrew|Stamp, Gordon|Gonza
PMID: 24308032
Journal: Oncol Res. 2013;20(9):393-402.
Title: Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells.
Author: Lee, Kyung Hee|Koh, Sung Ae|Kim, Jae-Ryong
PMID: 23924923
Journal: Dig Dis Sci. 2013 Jul;58(7):2038-45.
Title: MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer.
Author: Dong, Wenjie|Wang, Liping|Shen, Ruizhe
PMID: 23456500
Journal: Cancer Lett. 2013 Jul 10;335(1):128-35.
Title: Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer.
Author: Wu, Xiongyan|Chen, Xuehua|Zhou, Quan|Li, Pu|Yu, Beiqin|Li, Jianfang|Qu, Ying|Yan, Jun|Yu, Yingyan|Yan, Min|Zhu, Zhenggang|Liu, Bingya|Su, Liping
PMID: 23402812
Journal: J Pharm Sci. 2014 Jan;103(1):328-36.
Title: Population pharmacokinetics of rilotumumab, a fully human monoclonal antibody against hepatocyte growth factor, in cancer patients.
Author: Zhu, Min|Doshi, Sameer|Gisleskog, Per O|Oliner, Kelly S|Perez Ruixo, Juan Jose|Loh, Elwyn|Zhang, Yilong
PMID: 24186235
Journal: Lancet Oncol. 2014 Aug;15(9):914-6.
Title: Targeting the HGF/MET pathway in gastric cancer.
Author: Lordick, Florian
PMID: 24965570
Journal: Helicobacter. 2014 Sep;19 Suppl 1:32-7.
Title: Gastric cancer--epidemiologic and clinical aspects.
Author: Venerito, Marino|Nardone, Gerardo|Selgrad, Michael|Rokkas, Theodoros|Malfertheiner, Peter
PMID: 25167943
Journal: Cancer Discov. 2014 Sep;4(9):OF1.
Title: Rilotumumab extends PFS in gastric cancer.
Author:
PMID: 25185191
Journal: Clin Exp Metastasis. 2014 Oct;31(7):805-15.
Title: RhoGDI2 is associated with HGF-mediated tumor invasion through VEGF in stomach cancer.
Author: Koh, Sung Ae|Kim, Min Kyoung|Lee, Kyung Hee|Kim, Sang Woon|Kim, Jae-Ryong
PMID: 25253431
Journal: Gastrointest Tumors. 2014 May;1(4):180-94.
Title: Gastric Cancer: New Drugs - New Strategies.
Author: Schulte, Nadin|Ebert, Matthias P|Hartel, Nicola
PMID: 26674336
Journal: Mol Cancer Ther. 2015 Feb;14(2):384-94.
Title: The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer.
Author: Egile, Coumaran|Kenigsberg, Mireille|Delaisi, Christine|Begassat, Francoise|Do-Vale, Veronique|Mestadier, Jessica|Bonche, Fabrice|Benard, Tsiala|Nicolas, Jean-Paul|Valence, Sandrine|Lefranc, Celine|Francesconi, Elisa|Castell, Christelle|Lefebvre, Anne-Mar
PMID: 25504634
Journal: Oncotarget. 2015 Sep 22;6(28):24750-79.
Title: Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy.
Author: Riquelme, Ismael|Saavedra, Kathleen|Espinoza, Jaime A|Weber, Helga|Garcia, Patricia|Nervi, Bruno|Garrido, Marcelo|Corvalan, Alejandro H|Roa, Juan Carlos|Bizama, Carolina
PMID: 26267324
Journal: Cell Death Dis. 2015 Jul 2;6:e1802.
Title: LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer.
Author: Liu, Y-w|Sun, M|Xia, R|Zhang, E-b|Liu, X-h|Zhang, Z-h|Xu, T-p|De, W|Liu, B-r|Wang, Z-x
PMID: 26136075
Journal: Mol Oncol. 2015 Nov;9(9):1760-72.
Title: Inhibition of ligand-independent constitutive activation of the Met oncogenic receptor by the engineered chemically-modified antibody DN30.
Author: Vigna, Elisa|Chiriaco, Cristina|Cignetto, Simona|Fontani, Lara|Basilico, Cristina|Petronzelli, Fiorella|Comoglio, Paolo M
PMID: 26119717
Journal: APMIS. 2015 May;123(5):365-72.
Title: Targeted therapy in gastric cancer.
Author: Thiel, Alexandra|Ristimaki, Ari
PMID: 25706252
Journal: Mol Med Rep. 2015 May;11(5):3423-31.
Title: Clinical significance of hepatocyte growth factor/c-Met expression in the assessment of gastric cancer progression.
Author: Noguchi, Eiichiro|Saito, Noboru|Kobayashi, Makio|Kameoka, Shingo
PMID: 25592281
Journal: Cancer Lett. 2015 Aug 28;365(1):30-6.
Title: c-Met targeting in advanced gastric cancer: An open challenge.
Author: Marano, Luigi|Chiari, Rita|Fabozzi, Alessio|De Vita, Ferdinando|Boccardi, Virginia|Roviello, Giandomenico|Petrioli, Roberto|Marrelli, Daniele|Roviello, Franco|Patriti, Alberto
PMID: 26049023
Journal: Stem Cells. 2016 Apr;34(4):1011-26.
Title: Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis.
Author: Berger, Liron|Shamai, Yeela|Skorecki, Karl L|Tzukerman, Maty
PMID: 26676563
Journal: J Exp Clin Cancer Res. 2016 Jan 22;35:16.
Title: Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors.
Author: Li, Linhao|Jiang, Xian|Zhang, Qian|Dong, Xuesong|Gao, Yuqiang|He, Yuanlong|Qiao, Haiquan|Xie, Fangyu|Xie, Xiangjun|Sun, Xueying
PMID: 26795388
Journal: Gastroenterol Res Pract. 2016;2016:4105615.
Title: Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application.
Author: Li, Kaichun|Li, Jin
PMID: 26880889
Journal: Int J Cancer. 2016 Oct 15;139(8):1851-63.
Title: A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors.
Author: Gonzalez, Alexandra|Broussas, Matthieu|Beau-Larvor, Charlotte|Haeuw, Jean-Francois|Boute, Nicolas|Robert, Alain|Champion, Thierry|Beck, Alain|Bailly, Christian|Corvaia, Nathalie|Goetsch, Liliane
PMID: 27144973
Journal: Oncotarget. 2016 Jun 7;7(23):34190-200.
Title: PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.
Author: Wu, Yan|Yao, Xiaoyuan|Zhu, Miaolin|Qian, Hai|Jiang, Lu|Lan, Ting|Wu, Min|Pang, Ji|Chen, Yongchang
PMID: 27147579
Journal: J Med Chem. 2016 Aug 11;59(15):7066-74.
Title: Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazo l-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).
Author: Ugolini, Antonio|Kenigsberg, Mireille|Rak, Alexey|Vallee, Francois|Houtmann, Jacques|Lowinski, Maryse|Capdevila, Cecile|Khider, Jean|Albert, Eva|Martinet, Nathalie|Nemecek, Conception|Grapinet, Sandrine|Bacque, Eric|Roesner, Manfred|Delaisi, Christine|Cal
PMID: 27355974
Journal: Cancer Sci. 2017 Mar;108(3):296-307.
Title: Hepatocyte growth factor/MET in cancer progression and biomarker discovery.
Author: Matsumoto, Kunio|Umitsu, Masataka|De Silva, Dinuka M|Roy, Arpita|Bottaro, Donald P
PMID: 28064454
Journal: Klin Onkol. 2017 Winter;30(Supplementum3):50-54.
Title: [Checkpoint Inhibitors in the Treatment of Upper Gastrointestinal Tract Tumors].
Author: Obermannova, R
PMID: 29239193
Journal: Cell Physiol Biochem. 2017;42(4):1670-1683.
Title: miR-26a/b Inhibit Tumor Growth and Angiogenesis by Targeting the HGF-VEGF Axis in Gastric Carcinoma.
Author: Si, Yiran|Zhang, Haiyang|Ning, Tao|Bai, Ming|Wang, Yi|Yang, Haiou|Wang, Xinyi|Li, Jialu|Ying, Guoguang|Ba, Yi
PMID: 28738343
Journal: Pathol Res Pract. 2017 Sep;213(9):1221-1226.
Title: Predictive value for lymph node metastasis of epithelial-mesenchymal transition and cancer stem cell marker expression in early gastric cancer.
Author: Nam, Kyung Han|Yoon, Hyuk|Lee, Kyungbun|Park, Do Joong|Kim, Hyung-Ho|Lee, Hye Seung|Shin, Eun
PMID: 28595915
Journal: Eur J Med Chem. 2017 Jul 7;134:147-158.
Title: Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization.
Author: Zhao, Fei|Zhang, Le-Duo|Hao, Yu|Chen, Na|Bai, Rui|Wang, Yu-Ji|Zhang, Chun-Chun|Li, Gong-Sheng|Hao, Li-Jun|Shi, Chen|Zhang, Jing|Mao, Yu|Fan, Yi|Xia, Guang-Xin|Yu, Jian-Xin|Liu, Yan-Jun
PMID: 28411455
Journal: Cancer Sci. 2018 Mar;109(3):629-641.
Title: Exosomes serve as nanoparticles to suppress tumor growth and angiogenesis in gastric cancer by delivering hepatocyte growth factor siRNA.
Author: Zhang, Haiyang|Wang, Yi|Bai, Ming|Wang, Junyi|Zhu, Kegan|Liu, Rui|Ge, Shaohua|Li, JiaLu|Ning, Tao|Deng, Ting|Fan, Qian|Li, Hongli|Sun, Wu|Ying, Guoguang|Ba, Yi
PMID: 29285843
Journal: Oncol Rep. 2018 Aug;40(2):1185-1195.
Title: HGF derived from cancerassociated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.
Author: Ding, Xusheng|Xi, Wenqi|Ji, Jun|Cai, Qu|Jiang, Jinling|Shi, Min|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 29917165
Journal: Ann Transl Med. 2018 Jun;6(12):247.
Title: Current advances of targeting HGF/c-Met pathway in gastric cancer.
Author: Anestis, Aristomenis|Zoi, Ilianna|Karamouzis, Michalis V
PMID: 30069449
Journal: Oncol Lett. 2018 Nov;16(5):5983-5991.
Title: Hepatocyte growth factor-induced mesenchymal-epithelial transition factor activation leads to insulin-like growth factor 1 receptor inhibitor unresponsiveness in gastric cancer cells.
Author: Liu, Rujiao|Tang, Wenbo|Han, Xiaotian|Geng, Ruixuan|Wang, Chenchen|Zhang, Zhe
PMID: 30333869