Primary Site >> Colorectal Cancer

Gene >> HGF

Journal: Semin Liver Dis. 1992 Aug;12(3):265-78.
Title: Cellular and molecular mechanisms of hepatocarcinogenesis.
Author: Rogler, C E|Chisari, F V
PMID: 1439879
Journal: Gan To Kagaku Ryoho. 1993 Feb;20(3):326-31.
Title: [Metastasis related genes and malignancy in human esophageal, gastric and colorectal cancers].
Author: Tahara, E|Kuniyasu, H|Nakayama, H|Yasui, W|Yokozaki, H
PMID: 8094950
Journal: Clin Exp Metastasis. 1993 May;11(3):235-42.
Title: Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor.
Author: Jiang, W G|Lloyds, D|Puntis, M C|Nakamura, T|Hallett, M B
PMID: 8386069
Journal: J Cancer Res Clin Oncol. 1993;119(5):265-72.
Title: Molecular mechanism of stomach carcinogenesis.
Author: Tahara, E
PMID: 8440743
Journal: Gan To Kagaku Ryoho. 1994 Nov;21(15):2541-8.
Title: [Metastasis-related genes].
Author: Yokozaki, H|Tahara, E
PMID: 7526801
Journal: Biochem Biophys Res Commun. 1994 Jul 29;202(2):701-9.
Title: Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration.
Author: Dignass, A U|Lynch-Devaney, K|Podolsky, D K
PMID: 8048940
Journal: Clin Exp Metastasis. 1994 Mar;12(2):143-54.
Title: Hepatocyte growth factor stimulates invasion across reconstituted basement membranes by a new human small intestinal cell line.
Author: Sunitha, I|Meighen, D L|Hartman, D P|Thompson, E W|Byers, S W|Avigan, M I
PMID: 8306528
Journal: Gastroenterol Clin Biol. 1996;20(5):438-45.
Title: [Expression of hepatocyte growth factor and its receptor, C-Met in human digestive tissues and different gastric and colonic cancer cell lines].
Author: Kermorgant, S|Cadiot, G|Lewin, M J|Lehy, T
PMID: 8761141
Journal: J Cell Biochem. 1996 Sep 15;62(4):443-53.
Title: Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas.
Author: Uchiyama, A|Essner, R|Doi, F|Nguyen, T|Ramming, K P|Nakamura, T|Morton, D L|Hoon, D S
PMID: 8891890
Journal: Br J Cancer. 1997;75(2):241-50.
Title: Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.
Author: Empereur, S|Djelloul, S|Di Gioia, Y|Bruyneel, E|Mareel, M|Van Hengel, J|Van Roy, F|Comoglio, P|Courtneidge, S|Paraskeva, C|Chastre, E|Gespach, C
PMID: 9010033
Journal: Oncol Rep. 1997 Nov-Dec;4(6):1239-41.
Title: Increased concentration of hepatocyte growth factor in the sera of patients with gastrointestinal cancer.
Author: Narita, T|Mitsuoka, C|Kimura, N|Toi, M|Nakashio, T|Sekiguchi, K|Iwanari, H|Kannagi, R
PMID: 21590229
Journal: J Cell Sci. 1998 Apr;111 ( Pt 8):1039-49.
Title: Modulation of hepatocyte growth factor-induced scattering of HT29 colon carcinoma cells. Involvement of the MAPK pathway.
Author: Herrera, R
PMID: 9512500
Journal: Br J Cancer. 1998 Aug;78(4):454-9.
Title: Serum hepatocyte growth factor as an index of disease status of patients with colorectal carcinoma.
Author: Fukuura, T|Miki, C|Inoue, T|Matsumoto, K|Suzuki, H
PMID: 9716026
Journal: Biochem Biophys Res Commun. 1999 Aug 2;261(2):406-11.
Title: Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells.
Author: Hiscox, S|Jiang, W G
PMID: 10425198
Journal: Cancer Res. 1999 Sep 1;59(17):4427-34.
Title: CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins.
Author: Fujisaki, T|Tanaka, Y|Fujii, K|Mine, S|Saito, K|Yamada, S|Yamashita, U|Irimura, T|Eto, S
PMID: 10485493
Journal: Int J Cancer. 2000 Feb 15;85(4):563-70.
Title: Nk4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells.
Author: Parr, C|Hiscox, S|Nakamura, T|Matsumoto, K|Jiang, W G
PMID: 10699931
Journal: Inflamm Res. 2000 Jul;49(7):320-4.
Title: Expression of hepatocyte growth factor and c-met in ulcerative colitis.
Author: Kitamura, S|Kondo, S|Shinomura, Y|Isozaki, K|Kanayama, S|Higashimoto, Y|Minami, T|Kiyohara, T|Yasunaga, Y|Ishikawa, H|Ohtani, T|Ishiguro, S|Matsuzawa, Y
PMID: 10959552
Journal: Am J Pathol. 2000 Nov;157(5):1563-73.
Title: Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancer.
Author: Wielenga, V J|van der Voort, R|Taher, T E|Smit, L|Beuling, E A|van Krimpen, C|Spaargaren, M|Pals, S T
PMID: 11073815
Journal: Jpn J Cancer Res. 2000 Dec;91(12):1285-95.
Title: In vivo and in vitro interactions between human colon carcinoma cells and hepatic stellate cells.
Author: Shimizu, S|Yamada, N|Sawada, T|Ikeda, K|Kawada, N|Seki, S|Kaneda, K|Hirakawa, K
PMID: 11123428
Journal: Clin Exp Metastasis. 2000;18(8):639-49.
Title: Experimental and clinicopathologic studies on the function of the HGF receptor in human colon cancer metastasis.
Author: Fazekas, K|Csuka, O|Koves, I|Raso, E|Timar, J
PMID: 11827067
Journal: Hum Cell. 2001 Mar;14(1):83-93.
Title: Pericellular activation of hepatocyte growth factor/scatter factor (HGF/SF) in colorectal carcinomas: roles of HGF activator (HGFA) and HGFA inhibitor type 1 (HAI-1).
Author: Kataoka, H|Itoh, H|Hamasuna, R|Meng, J Y|Koono, M
PMID: 11436357
Journal: J Int Med Res. 2001 Sep-Oct;29(5):409-20.
Title: Bacterial lipopolysaccharide induces transforming growth factor beta and hepatocyte growth factor through toll-like receptor 2 in cultured human colon cancer cells.
Author: Yoshioka, T|Morimoto, Y|Iwagaki, H|Itoh, H|Saito, S|Kobayashi, N|Yagi, T|Tanaka, N
PMID: 11725828
Journal: J Pediatr Gastroenterol Nutr. 2001 Nov;33(5):548-53.
Title: Elevated serum hepatocyte growth factor in children and young adults with inflammatory bowel disease.
Author: Srivastava, M|Zurakowski, D|Cheifetz, P|Leichtner, A|Bousvaros, A
PMID: 11740227
Journal: Med Sci Monit. 2002 Oct;8(10):CR690-6.
Title: Hepatocyte growth factor levels in liver and blood, and post-operative liver cell proliferation in patients with benign and malignant liver tumors after partial hepatectomy.
Author: Dluzniewska, Joanna|Zolich, Dorota|Polanski, Jerzy|Zajac, Leszek|Sitkiewicz, Dariusz|Lukomska, Barbara
PMID: 12388921
Journal: Mol Cancer Res. 2003 Mar;1(5):393-401.
Title: Met receptor overexpression and oncogenic Ki-ras mutation cooperate to enhance tumorigenicity of colon cancer cells in vivo.
Author: Long, Isolde Seiden|Han, Kathy|Li, Ming|Shirasawa, Senji|Sasazuki, Takehiko|Johnston, Michael|Tsao, Ming-Sound
PMID: 12651912
Journal: Clin Exp Metastasis. 2003;20(4):291-300.
Title: Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin.
Author: Herynk, Matthew H|Tsan, Rachael|Radinsky, Robert|Gallick, Gary E
PMID: 12856716
Journal: FASEB J. 2003 Sep;17(12):1640-7.
Title: Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.
Author: Pai, Rama|Nakamura, Toshikazu|Moon, Woo S|Tarnawski, Andrzej S
PMID: 12958170
Journal: Exp Cell Res. 2004 Jan 15;292(2):274-87.
Title: HGF and ligation of alphavbeta5 integrin induce a novel, cancer cell-specific gene expression required for cell scattering.
Author: Crouch, Sonya|Spidel, Celee S|Lindsey, J Suzanne
PMID: 14697335
Journal: Biol Pharm Bull. 2004 Apr;27(4):578-82.
Title: Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells.
Author: Ogasawara, Masaru|Suzuki, Hideyo
PMID: 15056871
Journal: FASEB J. 2004 Jun;18(9):1016-8. Epub 2004 Apr 1.
Title: Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac.
Author: De Wever, Olivier|Nguyen, Quang-De|Van Hoorde, Leen|Bracke, Marc|Bruyneel, Erik|Gespach, Christian|Mareel, Marc
PMID: 15059978
Journal: Oncogene. 2004 Apr 22;23(19):3317-27.
Title: Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes.
Author: Rivat, Christine|De Wever, Olivier|Bruyneel, Erik|Mareel, Marc|Gespach, Christian|Attoub, Samir
PMID: 15077188
Journal: Nutr Cancer. 2004;48(2):182-8.
Title: Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity.
Author: Fenton, Jenifer I|Hord, Norman G
PMID: 15231453
Journal: Eur J Cancer. 2005 Mar;41(4):555-63.
Title: Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer.
Author: Jayson, Gordon C|Mulatero, Clive|Ranson, Malcolm|Zweit, Jamal|Jackson, Alan|Broughton, Lynn|Wagstaff, John|Hakansson, Leif|Groenewegen, Gerard|Lawrance, Jeremy|Tang, Meina|Wauk, Linda|Levitt, Dan|Marreaud, Sandrine|Lehmann, Frederic F|Herold, Manfred|Zwie
PMID: 15737560
Journal: Br J Cancer. 2005 Mar 28;92(6):1078-83.
Title: MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling.
Author: Boon, E M J|Kovarikova, M|Derksen, P W B|van der Neut, R
PMID: 15785735
Journal: Ann Surg. 2005 May;241(5):748-56; discussion 756-8.
Title: Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.
Author: Bauer, Todd W|Fan, Fan|Liu, Wenbiao|Johnson, Marjorie|Parikh, Nila U|Parry, Graham C|Callahan, Jennifer|Mazar, Andrew P|Gallick, Gary E|Ellis, Lee M
PMID: 15849510
Journal: World J Gastroenterol. 2005 Jul 7;11(25):3877-81.
Title: Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro.
Author: Li, Hong-Wu|Shan, Ji-Xian
PMID: 15991286
Journal: Shi Yan Sheng Wu Xue Bao. 2005 Jun;38(3):183-9.
Title: [Effect of HAI-1 over-expression on in vitro growth and migration/motility of SW620 cells].
Author: Cao, Jiang|Ye, Jing Jia
PMID: 16044910
Journal: Oncogene. 2006 Jan 5;25(1):91-102.
Title: Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer.
Author: Seiden-Long, I M|Brown, K R|Shih, W|Wigle, D A|Radulovich, N|Jurisica, I|Tsao, M-S
PMID: 16158056
Journal: J Cancer Res Clin Oncol. 2006 Jan;132(1):41-4.
Title: Impact of laparotomy and liver resection on the peritoneal concentrations of fibroblast growth factor 2, vascular endothelial growth factor and hepatocyte growth factor.
Author: Whitworth, M K|Sheen, A|Rosa, D D|Duff, S E|Ryder, D|Burumdayal, A|Wiener, K|Hawkins, R E|Saunders, M|Valle, J W|Sherlock, D|Jayson, G C
PMID: 16249905
Journal: Ann Surg Oncol. 2006 Mar;13(3):353-62.
Title: Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastases.
Author: Yoon, Sam S|Kim, Sung H|Gonen, Mithat|Heffernan, Nancy M|Detwiller, Kara Y|Jarnagin, William R|D'Angelica, Michael|Blumgart, Leslie H|Tanabe, Kenneth K|Dematteo, Ronald P
PMID: 16474912
Journal: Surgery. 2006 Mar;139(3):305-11.
Title: Genomic instability and tissue expression of angiogenic growth factors in sporadic colorectal cancer.
Author: Inoue, Yasuhiro|Miki, Chikao|Watanabe, Hideki|Ojima, Eiki|Kusunoki, Masato
PMID: 16546493
Journal: Cell Signal. 2006 Nov;18(11):1967-76. Epub 2006 May 3.
Title: Hepatocyte growth factor installs a survival platform for colorectal cancer cell invasive growth and overcomes p38 MAPK-mediated apoptosis.
Author: Fassetta, Michela|D'Alessandro, Lorenza|Coltella, Nadia|Di Renzo, Maria Flavia|Rasola, Andrea
PMID: 16677802
Journal: Acta Med Okayama. 2006 Dec;60(6):325-30.
Title: Study of interleukin-6 in the spread of colorectal cancer: the diagnostic significance of IL-6.
Author: Ashizawa, Tatsuto|Okada, Ryosuke|Suzuki, Yoshiaki|Takagi, Makoto|Yamazaki, Tatsuyuki|Sumi, Tetsuo|Aoki, Toshiaki|Aoki, Tatsuya
PMID: 17189976
Journal: Cancer Lett. 2007 Apr 18;248(2):219-28. Epub 2006 Sep 1.
Title: Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome.
Author: Kammula, Udai S|Kuntz, Eleanor J|Francone, Todd D|Zeng, Zhaoshi|Shia, Jinru|Landmann, Ron G|Paty, Philip B|Weiser, Martin R
PMID: 16945480
Journal: Oncogene. 2007 Feb 15;26(7):1078-87. Epub 2006 Sep 4.
Title: A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth.
Author: Rasola, A|Fassetta, M|De Bacco, F|D'Alessandro, L|Gramaglia, D|Di Renzo, M F|Comoglio, P M
PMID: 16953230
Journal: Biochem Biophys Res Commun. 2007 Jun 22;358(1):117-23.
Title: Inhibition of colon cancer growth and metastasis by NK4 gene repetitive delivery in mice.
Author: Wen, Jinhua|Matsumoto, Kunio|Taniura, Naoko|Tomioka, Daisaku|Nakamura, Toshikazu
PMID: 17467663
Journal: Int J Oncol. 2007 Jul;31(1):199-204.
Title: Quantification of MET and hepatocyte growth factor/scatter factor expression in colorectal adenomas, carcinomas and non-neoplastic epithelia by quantitative laser scanning microscopy.
Author: Baldus, Stephan E|Kort, Eric J|Schirmacher, Peter|Dienes, Hans P|Resau, James H
PMID: 17549422
Journal: J Exp Ther Oncol. 2007;6(3):205-17.
Title: Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells.
Author: Herynk, Matthew H|Zhang, Jing|Parikh, Nila U|Gallick, Gary E
PMID: 17552361
Journal: Hum Pathol. 2008 Oct;39(10):1483-94.
Title: Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author: Furlan, Daniela|Sahnane, Nora|Carnevali, Ileana|Cerutti, Roberta|Bertoni, Francesco|Kwee, Ivo|Uccella, Silvia|Bertolini, Valentina|Chiaravalli, Anna Maria|Capella, Carlo
PMID: 18619649
Journal: Mol Cancer Ther. 2008 Sep;7(9):2855-65.
Title: AAV-HGFK1 and Ad-p53 cocktail therapy prolongs survival of mice with colon cancer.
Author: Nie, Biao|Shen, Zan|Wen, Jun-Bao|Wong, Oscar Gee-Wan|Hsueh, Wayne D|Huo, Long-Fei|Kung, Hsiang-Fu|Jiang, Bo|Lin, Marie C M
PMID: 18790766
Journal: Hepatogastroenterology. 2008 Jul-Aug;55(85):1439-44.
Title: Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis.
Author: Gotohda, Naoto|Iwagaki, Hiromi|Ozaki, Michitaka|Kinoshita, Taira|Konishi, Masaru|Nakagohri, Toshio|Takahashi, Shinichiro|Saito, Shinya|Yagi, Takahito|Tanaka, Noriaki
PMID: 18795707
Journal: Nat Med. 2009 Jan;15(1):59-67.
Title: MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Author: Stein, Ulrike|Walther, Wolfgang|Arlt, Franziska|Schwabe, Holger|Smith, Janice|Fichtner, Iduna|Birchmeier, Walter|Schlag, Peter M
PMID: 19098908
Journal: Int J Oncol. 2009 Feb;34(2):355-60.
Title: Keratinocyte growth factor induces vascular endothelial growth factor-A expression in colorectal cancer cells.
Author: Narita, Kosuke|Fujii, Takenori|Ishiwata, Toshiyuki|Yamamoto, Tetsushi|Kawamoto, Yoko|Kawahara, Kiyoko|Nakazawa, Nando|Naito, Zenya
PMID: 19148469
Journal: Oncogene. 2009 Mar 12;28(10):1357-65.
Title: Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
Author: Sagara, M|Kawasaki, Y|Iemura, S-i|Natsume, T|Takai, Y|Akiyama, T
PMID: 19151759
Journal: Clin Exp Metastasis. 2009;26(5):447-56.
Title: NK4, an HGF antagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cells.
Author: Kubota, Takeshi|Taiyoh, Hiroaki|Matsumura, Atsushi|Murayama, Yasutoshi|Ichikawa, Daisuke|Okamoto, Kazuma|Fujiwara, Hitoshi|Ikoma, Hisashi|Nakanishi, Masayoshi|Kikuchi, Shojiro|Sakakura, Chouhei|Ochiai, Toshiya|Kokuba, Yukihito|Taniguchi, Hiroki|Sonoyama,
PMID: 19234748
Journal: Genome Med. 2009 Apr 2;1(4):36.
Title: Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer.
Author: Boardman, Lisa A
PMID: 19341507
Journal: J Biol Chem. 2009 Aug 14;284(33):22436-43.
Title: Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase.
Author: Kawasaki, Yoshihiro|Tsuji, Shinnosuke|Sagara, Masaki|Echizen, Kanae|Shibata, Yoko|Akiyama, Tetsu
PMID: 19525225
Journal: Int J Cancer. 2009 Oct 1;125(7):1657-62.
Title: Serum hepatocyte growth factor as a prognostic marker for stage II or III colorectal cancer patients.
Author: Toiyama, Yuji|Miki, Chikao|Inoue, Yasuhiro|Okugawa, Yoshinaga|Tanaka, Kouji|Kusunoki, Masato
PMID: 19569242
Journal: Int J Biochem Cell Biol. 2009 Dec;41(12):2356-9.
Title: Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Author: Arlt, Franziska|Stein, Ulrike
PMID: 19666136
Journal: Biochem Biophys Res Commun. 2009 Nov 20;389(3):527-30.
Title: Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide.
Author: Larsen, Christine A|Dashwood, Roderick H
PMID: 19744467
Journal: J Biol Chem. 2010 Jun 25;285(26):19821-32.
Title: Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor.
Author: Ghatak, Shibnath|Hascall, Vincent C|Markwald, Roger R|Misra, Suniti
PMID: 20200161
Journal: Indian J Exp Biol. 2010 Apr;48(4):354-64.
Title: Hepatocyte growth factor (HGF), heat shock proteins (HSPs) and multidrug resistance protein (MRP) expression in co-culture of colon tumor spheroids with normal cells after incubation with interleukin-1beta (IL-1beta) and/or camptothecin (CPT-11).
Author: Paduch, Roman|Jakubowicz-Gil, Joanna|Niedziela, Piotr
PMID: 20726333
Journal: J Clin Invest. 2010 Dec;120(12):4493-506.
Title: Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.
Author: Jung, Cho-Rok|Lim, Jung Hwa|Choi, Yoonjung|Kim, Dae-Ghon|Kang, Koo Jeong|Noh, Seung-Moo|Im, Dong-Soo
PMID: 21060154
Journal: PLoS One. 2010 Nov 30;5(11):e14127.
Title: Independent interactions of phosphorylated beta-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions.
Author: Faux, Maree C|Coates, Janine L|Kershaw, Nadia J|Layton, Meredith J|Burgess, Antony W
PMID: 21152425
Journal: J Diet Suppl. 2010 Dec;7(4):325-40.
Title: Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.
Author: McCabe, Jonathan|Chang, Sarah|Hajibandeh, Jeffrey|Tran, Michael D|Meeder, Colby A|Sharma, Kanika|Nguyen, Dieu-Hoa|Moody, Michael|Keiserman, Mark A|Bergman, Christine J|Kingsley, Karl
PMID: 22432562
Journal: Cancer Res. 2011 Jan 1;71(1):61-7.
Title: In vivo antitumor activity of a recombinant IL-7/HGFbeta hybrid cytokine in mice.
Author: Lai, Laijun|Jin, Jingjun|Goldschneider, Irving
PMID: 21084268
Journal: Surg Innov. 2011 Sep;18(3):254-8.
Title: Minimally invasive colorectal resection is associated with a transient increase in plasma hepatocyte growth factor levels early after surgery for colon cancer.
Author: Shantha Kumara, H M C|Tohme, Samer T|Kim, Ik Y|Kim, Donald G|Kalady, Matthew F|Luchtefeld, Martin|Hoffman, Keith|Dimaggio, Vincent|Whelan, Richard L
PMID: 21398340
Journal: HPB (Oxford). 2011 Apr;13(4):246-55.
Title: Changes in growth factor levels after thermal ablation in a murine model of colorectal liver metastases.
Author: Fifis, Theodora|Malcontenti-Wilson, Caterina|Amijoyo, Jason|Anggono, Beatrice|Muralidharan, Vijayaragavan|Nikfarjam, Mehrdad|Christophi, Christopher
PMID: 21418130
Journal: Clin Cancer Res. 2011 May 15;17(10):3146-56.
Title: Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations.
Author: Galimi, Francesco|Torti, Davide|Sassi, Francesco|Isella, Claudio|Cora, Davide|Gastaldi, Stefania|Ribero, Dario|Muratore, Andrea|Massucco, Paolo|Siatis, Dimitrios|Paraluppi, Gianluca|Gonella, Federica|Maione, Francesca|Pisacane, Alberto|David, Ezio|Torchio
PMID: 21447729
Journal: J Agric Food Chem. 2011 May 25;59(10):5357-63.
Title: Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin.
Author: Chang, Hsiang-Yu|Kao, Ming-Ching|Way, Tzong-Der|Ho, Chi-Tang|Fu, Earl
PMID: 21504235
Journal: Oncol Rep. 2011 Aug;26(2):335-41.
Title: Hepatocyte growth factor ameliorates mucosal injuries leading to inhibition of colon cancer development in mice.
Author: Yamaji, Naohisa|Ido, Akio|Moriuchi, Akihiro|Numata, Masatsugu|Setoyama, Hitoshi|Tamai, Tsutomu|Funakawa, Keita|Fujita, Hiroshi|Sakiyama, Toshio|Uto, Hirofumi|Oketani, Makoto|Tsubouchi, Hirohito
PMID: 21567095
Journal: J Proteome Res. 2011 Jul 1;10(7):3200-11.
Title: Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.
Author: Organ, Shawna L|Tong, Jiefei|Taylor, Paul|St-Germain, Jonathan R|Navab, Roya|Moran, Michael F|Tsao, Ming-Sound
PMID: 21609022
Journal: J Exp Clin Cancer Res. 2011 Sep 16;30:83.
Title: Effects of metastasis-associated in colon cancer 1 inhibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cells.
Author: Zhang, Ruitao|Shi, Huirong|Chen, Zhimin|Wu, Qinghua|Ren, Fang|Huang, Haoliang
PMID: 21923915
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Sep;31(9):1551-5.
Title: [Expressions of MACC1, HGF, and C-met protein in epithelial ovarian cancer and their significance].
Author: Zhang, Rui-tao|Shi, Hui-rong|Huang, Hao-liang|Chen, Zhi-min|Liu, Hui-na|Yuan, Zhong-fu
PMID: 21945764
Journal: PLoS One. 2011;6(11):e26450.
Title: Enhanced activity of meprin-alpha, a pro-migratory and pro-angiogenic protease, in colorectal cancer.
Author: Lottaz, Daniel|Maurer, Christoph A|Noel, Agnes|Blacher, Silvia|Huguenin, Maya|Nievergelt, Alexandra|Niggli, Verena|Kern, Alexander|Muller, Stefan|Seibold, Frank|Friess, Helmut|Becker-Pauly, Christoph|Stocker, Walter|Sterchi, Erwin E
PMID: 22096485
Journal: Oncogene. 2012 Jan 19;31(3):376-89.
Title: Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis.
Author: Swaminathan, G|Cartwright, C A
PMID: 21685945
Journal: BMC Cancer. 2012 Jan 17;12:20.
Title: A common variant of the MACC1 gene is significantly associated with overall survival in colorectal cancer patients.
Author: Lang, Alois H|Geller-Rhomberg, Simone|Winder, Thomas|Stark, Nicole|Gasser, Klaus|Hartmann, Bernd|Kohler, Bertram|Grizelj, Ina|Drexel, Heinz|Muendlein, Axel
PMID: 22251819
Journal: Tumori. 2012 Jan-Feb;98(1):105-12.
Title: Expression of the hepatocyte growth factor and c-Met in colon cancer: correlation with clinicopathological features and overall survival.
Author: Liu, Yao|Li, Qiaoyan|Zhu, Liwei
PMID: 22495710
Journal: Mol Cancer. 2012 Apr 25;11:23.
Title: MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer.
Author: Zhang, Yu|Wang, Zhongqiu|Chen, Min|Peng, Liang|Wang, Xinying|Ma, Qunying|Ma, Fengli|Jiang, Bo
PMID: 22533346
Journal: Med Oncol. 2012 Dec;29(5):3119-24.
Title: Prognostic value of tumor growth factor levels during chemotherapy in patients with metastatic colorectal cancer.
Author: Inanc, Mevlude|Er, Ozlem|Karaca, Halit|Berk, Veli|Ozkan, Metin|Saraymen, Recep|Elmali, Ferhan
PMID: 22580817
Journal: Oncol Rep. 2012 Sep;28(3):855-61.
Title: Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
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Journal: PLoS One. 2012;7(7):e42079.
Title: The aromatase gene (CYP19A1) variants and circulating hepatocyte growth factor in postmenopausal women.
Author: Lin, Jennifer H|Gunter, Marc J|Manson, JoAnn E|Rexrode, Kathryn M|Cook, Nancy R|Kraft, Peter|Cochrane, Barbara B|Chlebowski, Rowan T|Ho, Gloria Y F|Zhang, Shumin M
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Journal: PLoS One. 2012;7(11):e49249.
Title: Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
Author: Stein, Ulrike|Burock, Susen|Herrmann, Pia|Wendler, Ina|Niederstrasser, Markus|Wernecke, Klaus-Dieter|Schlag, Peter M
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Journal: J Agric Food Chem. 2012 Dec 26;60(51):12443-50.
Title: Human gut flora-fermented nondigestible fraction from cooked bean ( Phaseolus vulgaris L.) modifies protein expression associated with apoptosis, cell cycle arrest, and proliferation in human adenocarcinoma colon cancer cells.
Author: Campos-Vega, Rocio|Garcia-Gasca, Teresa|Guevara-Gonzalez, Ramon|Ramos-Gomez, Minerva|Oomah, B Dave|Loarca-Pina, Guadalupe
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Journal: Curr Pharm Des. 2013;19(5):841-63.
Title: Anti-metastatic treatment in colorectal cancer: targeting signaling pathways.
Author: Lemos, Clara|Sack, Ulrike|Schmid, Felicitas|Juneja, Manisha|Stein, Ulrike
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Journal: Front Biosci (Elite Ed). 2013 Jan 1;5:574-82.
Title: Effect of genomic instability and mutations on the signaling pathways in colon cancer cells.
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Journal: Oncol Rep. 2013 Apr;29(4):1570-8.
Title: CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer.
Author: Saito, Seiya|Okabe, Hirohisa|Watanabe, Masayuki|Ishimoto, Takatsugu|Iwatsuki, Masaaki|Baba, Yoshifumi|Tanaka, Youhei|Kurashige, Junji|Miyamoto, Yuji|Baba, Hideo
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Journal: Cancer Res. 2013 Apr 15;73(8):2659-70.
Title: Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis.
Author: Hoshiko, Shinri|Kawaguchi, Makiko|Fukushima, Tsuyoshi|Haruyama, Yukihiro|Yorita, Kenji|Tanaka, Hiroyuki|Seiki, Motoharu|Inatsu, Haruhiko|Kitamura, Kazuo|Kataoka, Hiroaki
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Journal: Int J Med Sci. 2013;10(5):548-59.
Title: Expression of HGF and Met in human tissues of colorectal cancers: biological and clinical implications for synchronous liver metastasis.
Author: Sun, Yan-lai|Liu, Wei-dong|Ma, Guo-yuan|Gao, Dong-wei|Jiang, Yuan-zhu|Liu, Qi|Du, Jia-jun
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Journal: J Cancer Res Clin Oncol. 2013 Jul;139(7):1169-78.
Title: Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Author: Chen, Qiang|Chen, Lei|Zhao, Ren|Yang, Xiao-dong|Imran, Khan|Xing, Chun-gen
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Journal: Ann Surg. 2013 Jun;257(6):1089-95.
Title: MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases.
Author: Isella, Claudio|Mellano, Alfredo|Galimi, Francesco|Petti, Consalvo|Capussotti, Lorenzo|De Simone, Michele|Bertotti, Andrea|Medico, Enzo|Muratore, Andrea
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Journal: Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title: Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
Author: Giampieri, Riccardo|Scartozzi, Mario|Del Prete, Michela|Maccaroni, Elena|Bittoni, Alessandro|Faloppi, Luca|Bianconi, Maristella|Cecchini, Luca|Cascinu, Stefano
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Journal: Chin Med J (Engl). 2013 Jul;126(14):2705-9.
Title: Effect of c-Met inhibitor SU11274 on human colon cancer cell growth.
Author: Gao, Shuo-hui|Liu, Chao|Wei, Jun|Feng, Ye
PMID: 23876900
Journal: Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G564-72.
Title: Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion.
Author: Swietlicki, Elzbieta A|Bala, Shashi|Lu, Jianyun|Shaker, Anisa|Kularatna, Gowri|Levin, Marc S|Rubin, Deborah C
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Journal: Int J Mol Sci. 2013 Sep 3;14(9):18056-77.
Title: Role of cMET in the development and progression of colorectal cancer.
Author: Samame Perez-Vargas, Juan Carlos|Biondani, Pamela|Maggi, Claudia|Gariboldi, Manuela|Gloghini, Annunziata|Inno, Alessandro|Volpi, Chiara Costanza|Gualeni, Ambra Vittoria|di Bartolomeo, Maria|de Braud, Filippo|Castano, Alessandra|Bossi, Ilaria|Pietrantonio,
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Journal: Clin Cancer Res. 2013 Dec 15;19(24):6751-65.
Title: Increased TGF-alpha as a mechanism of acquired resistance to the anti-EGFR inhibitor cetuximab through EGFR-MET interaction and activation of MET signaling in colon cancer cells.
Author: Troiani, Teresa|Martinelli, Erika|Napolitano, Stefania|Vitagliano, Donata|Ciuffreda, Loreta Pia|Costantino, Sara|Morgillo, Floriana|Capasso, Anna|Sforza, Vincenzo|Nappi, Anna|De Palma, Raffaele|D'Aiuto, Elena|Berrino, Liberato|Bianco, Roberto|Ciardiello,
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Journal: Cell Mol Life Sci. 2014 Jul;71(14):2759-73.
Title: A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions.
Author: Fram, Sally|King, Helen|Sacks, David B|Wells, Claire M
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Journal: Inflamm Bowel Dis. 2014 Apr;20(4):703-11.
Title: Expression of MACC1 and MET in inflammatory bowel disease-associated colonic neoplasia.
Author: Harpaz, Noam|Taboada, Sofia|Ko, Huaibin Mabel|Yu, Jiangzhou|Yang, Qi|Xu, Haodong|Cao, Wenqing
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Journal: Clin Cancer Res. 2014 May 15;20(10):2793-804.
Title: A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.
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Journal: Int J Mol Sci. 2014 Apr 4;15(4):5838-51.
Title: Cetuximab-induced MET activation acts as a novel resistance mechanism in colon cancer cells.
Author: Song, Na|Liu, Shizhou|Zhang, Jingdong|Liu, Jing|Xu, Ling|Liu, Yunpeng|Qu, Xiujuan
PMID: 24714091
Journal: PLoS One. 2014 May 13;9(5):e97432.
Title: Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model.
Author: Elliott, Victoria A|Rychahou, Piotr|Zaytseva, Yekaterina Y|Evers, B Mark
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Journal: Eur J Cancer. 2014 Aug;50(12):2134-41.
Title: Significant survival impact of MACC1 polymorphisms in HER2 positive breast cancer patients.
Author: Muendlein, Axel|Hubalek, Michael|Geller-Rhomberg, Simone|Gasser, Klaus|Winder, Thomas|Drexel, Heinz|Decker, Thomas|Mueller-Holzner, Elisabeth|Chamson, Martina|Marth, Christian|Lang, Alois H
PMID: 24910416
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jun;17(6):598-601.
Title: [Association of expression of HGF and its receptor c-Met to primary colorectal cancers with synchronous liver metastasis].
Author: Sun, Yanlai|Li, Zengjun|Xu, Zhongfa
PMID: 24953371
Journal: PLoS One. 2014 Aug 1;9(8):e103159.
Title: Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.
Author: Kirzin, Sylvain|Marisa, Laetitia|Guimbaud, Rosine|De Reynies, Aurelien|Legrain, Michele|Laurent-Puig, Pierre|Cordelier, Pierre|Pradere, Bernard|Bonnet, Delphine|Meggetto, Fabienne|Portier, Guillaume|Brousset, Pierre|Selves, Janick
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Journal: Oncol Rep. 2014 Dec;32(6):2359-64.
Title: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow.
Author: Tawada, Masahiro|Hayashi, Shin-Ichiro|Ikegame, Yuka|Nakashima, Shigeru|Yoshida, Kazuhiro
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Journal: Oncol Lett. 2014 Nov;8(5):2305-2309.
Title: MACC1 expression levels as a novel prognostic marker for colorectal cancer.
Author: Yamamoto, Hirofumi|Miyoshi, Norikatsu|Mimori, Koshi|Hitora, Toshiki|Tokuoka, Masayoshi|Fujino, Shiki|Ellis, Haley L|Ishii, Hideshi|Noura, Shingo|Ohue, Masayuki|Yano, Masahiko|Doki, Yuichiro|Mori, Masaki
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Journal: Biomedicines. 2014 Nov 25;2(4):345-358.
Title: Role of HGF-MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer.
Author: Della Corte, Carminia Maria|Fasano, Morena|Papaccio, Federica|Ciardiello, Fortunato|Morgillo, Floriana
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Journal: Gastroenterology. 2015 Jan;148(1):181-191.e17.
Title: Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis.
Author: Seneviratne, Danushka|Ma, Jihong|Tan, Xinping|Kwon, Yong-Kook|Muhammad, Eman|Melhem, Mona|DeFrances, Marie C|Zarnegar, Reza
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Journal: Mol Oncol. 2015 Feb;9(2):377-88.
Title: TNF-alpha promotes invasive growth through the MET signaling pathway.
Author: Bigatto, Viola|De Bacco, Francesca|Casanova, Elena|Reato, Gigliola|Lanzetti, Letizia|Isella, Claudio|Sarotto, Ivana|Comoglio, Paolo M|Boccaccio, Carla
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Journal: Cell Signal. 2015 Apr;27(4):860-6.
Title: HGF-activated colonic fibroblasts mediates carcinogenesis of colonic epithelial cancer cells via PKC-cMET-ERK1/2-COX-2 signaling.
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Journal: Int J Oncol. 2015 May;46(5):2143-53.
Title: Differential role of MACC1 expression and its regulation of the HGF/cMet pathway between breast and colorectal cancer.
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Journal: Clin Cancer Res. 2015 Apr 1;21(7):1752-63.
Title: BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs.
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Journal: Hepatology. 2015 Sep;62(3):841-50.
Title: Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in Klatskin tumor patients.
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Journal: Tumour Biol. 2015 Sep;36(10):7947-60.
Title: gamma-Synuclein confers both pro-invasive and doxorubicin-mediated pro-apoptotic properties to the colon adenocarcinoma LS 174T cell line.
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Journal: Front Oncol. 2015 Jun 3;5:125.
Title: Neuropilin-1 as Therapeutic Target for Malignant Melanoma.
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Journal: Oncotarget. 2015 Sep 15;6(27):24047-60.
Title: Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF.
Author: Woo, Jong Kyu|Kang, Ju-Hee|Kim, BoRa|Park, Byung Hee|Shin, Kum-Joo|Song, Seong-Won|Kim, Jung Ju|Kim, Hwan-Mook|Lee, Sang-Jin|Oh, Seung Hyun
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Journal: Oncol Lett. 2015 May;9(5):1989-1996.
Title: Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer.
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Journal: Mol Cancer Res. 2015 Nov;13(11):1478-86.
Title: Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon.
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Journal: Oncol Lett. 2016 Jan;11(1):731-734.
Title: Expression of hepatocyte growth factor and c-Met is characteristic of alpha-fetoprotein-producing colorectal adenocarcinoma: A report of three cases.
Author: Li, Jun|Liu, Yue|Xu, Jing-Hong|Xu, Zheng-Ping|Zheng, Shu|Ding, Ke-Feng
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Journal: Oncol Lett. 2016 Feb;11(2):1499-1505.
Title: Curcumin mediates reversion of HGF-induced epithelial-mesenchymal transition via inhibition of c-Met expression in DU145 cells.
Author: Hu, Hui-Jun|Lin, Xiao-Long|Liu, Mi-Hua|Fan, Xiao-Juan|Zou, Wei-Wen
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Journal: Anticancer Res. 2016 Apr;36(4):1901-7.
Title: Predictive Value of Growth Factors and Interleukins for Future Liver Remnant Volume and Colorectal Liver Metastasis Volume Growth Following Portal Vein Embolization and Autologous Stem Cell Application.
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PMID: 27069178
Journal: Oncotarget. 2016 Jul 12;7(28):43907-43923.
Title: Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice.
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Journal: BMC Cancer. 2016 Jun 13;16:366.
Title: PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study.
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Journal: Biomed Pharmacother. 2016 Aug;82:528-36.
Title: IGF1R and c-met as therapeutic targets for colorectal cancer.
Author: Shali, Hajar|Ahmadi, Majid|Kafil, Hossein Samadi|Dorosti, Abbasali|Yousefi, Mehdi
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Journal: Int J Cancer. 2016 Dec 1;139(11):2553-69.
Title: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.
Author: Xia, Jianling|Huang, Na|Huang, Hongxiang|Sun, Li|Dong, Shaoting|Su, Jinyu|Zhang, Jingwen|Wang, Lin|Lin, Li|Shi, Min|Bin, Jianping|Liao, Yulin|Li, Nailin|Liao, Wangjun
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Journal: Oncotarget. 2016 Nov 29;7(48):78932-78945.
Title: Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer.
Author: Bradley, Conor A|Dunne, Philip D|Bingham, Victoria|McQuaid, Stephen|Khawaja, Hajrah|Craig, Stephanie|James, Jackie|Moore, Wendy L|McArt, Darragh G|Lawler, Mark|Dasgupta, Sonali|Johnston, Patrick G|Van Schaeybroeck, Sandra
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Journal: Med Sci Monit. 2016 Nov 1;22:4126-4131.
Title: Effects and Mechanism of Imatinib in Inhibiting Colon Cancer Cell Proliferation.
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Journal: EJNMMI Res. 2016 Dec;6(1):92.
Title: Yttrium-90 radioembolization for colorectal cancer liver metastases: a prospective cohort study on circulating angiogenic factors and treatment response.
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Journal: Cancer Sci. 2017 Mar;108(3):296-307.
Title: Hepatocyte growth factor/MET in cancer progression and biomarker discovery.
Author: Matsumoto, Kunio|Umitsu, Masataka|De Silva, Dinuka M|Roy, Arpita|Bottaro, Donald P
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Journal: Colorectal Dis. 2017 May;19(5):O115-O125.
Title: Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study.
Author: Alonso, S|Mayol, X|Nonell, L|Salvans, S|Pascual, M|Pera, M
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Journal: Oncotarget. 2017 Jun 13;8(24):38193-38213.
Title: Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors.
Author: Mira, Alessia|Morello, Virginia|Cespedes, Maria Virtudes|Perera, Timothy|Comoglio, Paolo M|Mangues, Ramon|Michieli, Paolo
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Journal: Anticancer Res. 2017 May;37(5):2477-2486.
Title: Diagnostic Performance of a Novel Multiplex Immunoassay in Colorectal Cancer.
Author: Dressen, Katja|Hermann, Natalie|Manekeller, Steffen|Walgenbach-Bruenagel, Gisela|Schildberg, Frank A|Hettwer, Karina|Uhlig, Steffen|Kalff, Jorg C|Hartmann, Gunther|Holdenrieder, Stefan
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Journal: J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):923-927.
Title: Autophagy-related gene expression in colorectal cancer patients.
Author: Bednarczyk, M|Muc-Wierzgon, M|Waniczek, D|Fatyga, E|Klakla, K|Mazurek, U|Wierzgon, J
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Journal: Ann Clin Lab Sci. 2018 Mar;48(2):191-196.
Title: The Predictive Significance of Metastasis-Associated in Colon Cancer-1 (MACC1) in Primary Breast Cancer.
Author: Prguda-Mujic, Jasminka|Milde-Langosch, Karin|Mueller, Volkmar|Suljagic, Mirza|Coric, Jozo|Ler, Daria
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Journal: Int J Cancer. 2018 Apr 25.
Title: Targeting the MET oncogene by concomitant inhibition of receptor and ligand via an antibody-"decoy" strategy.
Author: Basilico, Cristina|Modica, Chiara|Maione, Federica|Vigna, Elisa|Comoglio, Paolo M
PMID: 29693242