Primary Site >> Colorectal Cancer

Gene >> HES1

Journal: Biochim Biophys Acta. 1989 May 31;991(2):280-3.
Title: Differential inhibitory action of the fungal toxin orellanine on alkaline phosphatase isoenzymes.
Author: Ruedl, C|Gstraunthaler, G|Moser, M
PMID: 2566329
Journal: Int J Oncol. 2007 Jan;30(1):247-51.
Title: Notch signaling in gastrointestinal tract (review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17143535
Journal: Int J Oncol. 2007 Aug;31(2):461-6.
Title: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17611704
Journal: Cell Oncol. 2008;30(1):1-11.
Title: Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases.
Author: Veenendaal, Liesbeth M|Kranenburg, Onno|Smakman, Niels|Klomp, Annemarie|Borel Rinkes, Inne H M|van Diest, Paul J
PMID: 18219106
Journal: Dig Dis Sci. 2008 Aug;53(8):2195-203.
Title: The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.
Author: Zhang, Hui|Ye, Yingjiang|Bai, Zhigang|Wang, Shan
PMID: 18320325
Journal: Int J Oncol. 2008 Dec;33(6):1223-9.
Title: Activation of Notch signaling in human colon adenocarcinoma.
Author: Reedijk, Michael|Odorcic, Silvia|Zhang, Hui|Chetty, Runjan|Tennert, Carsten|Dickson, Brendan C|Lockwood, Gina|Gallinger, Steven|Egan, Sean E
PMID: 19020755
Journal: Cancer Res. 2009 Jan 15;69(2):573-82.
Title: gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Author: Meng, Raymond D|Shelton, Christopher C|Li, Yue-Ming|Qin, Li-Xuan|Notterman, Daniel|Paty, Philip B|Schwartz, Gary K
PMID: 19147571
Journal: Int J Colorectal Dis. 2010 Dec;25(12):1407-15.
Title: The study of effect of tea polyphenols on microsatellite instability colorectal cancer and its molecular mechanism.
Author: Jin, Heiying|Tan, Xuanzhong|Liu, Xiufang|Ding, Yijiang
PMID: 20730438
Journal: Zhong Xi Yi Jie He Xue Bao. 2010 Sep;8(9):870-6.
Title: [Tea polyphenol inhibits colorectal cancer with microsatellite instability by regulating the expressions of HES1, JAG1, MT2A and MAFA].
Author: Xu, Yan-Yan|Jin, Hei-Ying|Tan, Xuan-Zhong|Liu, Xiu-Fang|Ding, Yi-Jiang
PMID: 20836978
Journal: Neoplasma. 2011;58(4):343-7.
Title: Gamma-secretase inhibitor, a potential target therapy for MUC2-positive colorectal carcinoma.
Author: Bu, X|Li, N|Tian, X|Huang, P
PMID: 21520992
Journal: Zhonghua Yi Xue Za Zhi. 2011 Nov 8;91(41):2891-4.
Title: [Expression pattern and clinical significance of hairy enhancer of split 1 in colorectal cancer].
Author: Jin, Hei-ying|Xu, Jun-hua|Wang, Xiao-feng|Ding, Yi-jiang
PMID: 22333607
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Aug;14(8):636-9.
Title: [Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1].
Author: Zhang, Chun-xia|Wang, Shui-ming|Jin, Hei-ying
PMID: 21866461
Journal: Gastroenterology. 2011 Sep;141(3):1003-1013.e1-10.
Title: Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.
Author: Feng, Ying|Bommer, Guido T|Zhao, Jenny|Green, Maranne|Sands, Evan|Zhai, Yali|Brown, Kelly|Burberry, Aaron|Cho, Kathleen R|Fearon, Eric R
PMID: 21699772
Journal: Chem Pharm Bull (Tokyo). 2011;59(4):417-26.
Title: Approaches to neural stem cells and cancer cells based on natural products.
Author: Arai, Midori A
PMID: 21467667
Journal: PLoS One. 2011 Mar 18;6(3):e17957.
Title: The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells.
Author: Ungerback, Jonas|Elander, Nils|Grunberg, John|Sigvardsson, Mikael|Soderkvist, Peter
PMID: 21437251
Journal: Gut. 2011 Feb;60(2):166-76.
Title: Complex interplay between beta-catenin signalling and Notch effectors in intestinal tumorigenesis.
Author: Peignon, Gregory|Durand, Aurelie|Cacheux, Wulfran|Ayrault, Olivier|Terris, Benoit|Laurent-Puig, Pierre|Shroyer, Noah F|Van Seuningen, Isabelle|Honjo, Tasuku|Perret, Christine|Romagnolo, Beatrice
PMID: 21205878
Journal: Eur J Cancer. 2012 May;48(7):997-1003.
Title: A phase II study of RO4929097 in metastatic colorectal cancer.
Author: Strosberg, Jonathan R|Yeatman, Timothy|Weber, Jill|Coppola, Domenico|Schell, Michael J|Han, Gang|Almhanna, Khaldoun|Kim, Richard|Valone, Tiffany|Jump, Helen|Sullivan, Dan
PMID: 22445247
Journal: Chem Biol Drug Des. 2013 Mar;81(3):334-42.
Title: Identification of small molecule Hes1 modulators as potential anticancer chemotherapeutics.
Author: Sail, Vibhavari|Hadden, M Kyle
PMID: 23006776
Journal: PLoS One. 2013;8(2):e55620.
Title: Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo.
Author: Becker, Svetlana|Oelschlaeger, Tobias A|Wullaert, Andy|Vlantis, Katerina|Pasparakis, Manolis|Wehkamp, Jan|Stange, Eduard F|Gersemann, Michael
PMID: 23418447
Journal: Onco Targets Ther. 2013;6:145-53.
Title: Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling.
Author: Jin, Heiying|Gong, Wei|Zhang, Chunxia|Wang, Shuiming
PMID: 23525843
Journal: Br J Cancer. 2013 Aug 20;109(4):1023-30.
Title: Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.
Author: Candy, P A|Phillips, M R|Redfern, A D|Colley, S M|Davidson, J A|Stuart, L M|Wood, B A|Zeps, N|Leedman, P J
PMID: 23900217
Journal: Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author: Zhou, Jin|Li, Pu|Xue, Xiaofeng|He, Songbing|Kuang, Yuting|Zhao, Hong|Chen, Shaoji|Zhi, Qiaoming|Guo, Xiaobo
PMID: 23916687
Journal: PLoS One. 2013 Oct 2;8(10):e76596.
Title: Knockdown of lymphoid enhancer factor 1 inhibits colon cancer progression in vitro and in vivo.
Author: Wang, Wen-Juan|Yao, Yu|Jiang, Li-Li|Hu, Ting-Hua|Ma, Jie-Qun|Liao, Zi-Jun|Yao, Jun-Tao|Li, Dong-Fan|Wang, Shu-Hong|Nan, Ke-Jun
PMID: 24098538
Journal: Zhonghua Gan Zang Bing Za Zhi. 2014 May;22(5):354-7.
Title: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells].
Author: Li, Jianfang|Ding, Shixiong|Ying, Liping|Hu, Airong|Hu, Yaoren|Liang, Xiaoyue
PMID: 25180870
Journal: Mol Cell Biochem. 2014 Nov;396(1-2):281-93.
Title: Colocalization of beta-catenin with Notch intracellular domain in colon cancer: a possible role of Notch1 signaling in activation of CyclinD1-mediated cell proliferation.
Author: Gopalakrishnan, Natarajan|Saravanakumar, Marimuthu|Madankumar, Perumal|Thiyagu, Mani|Devaraj, Halagowder
PMID: 25073953
Journal: Carcinogenesis. 2014 Apr;35(4):795-806.
Title: Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.
Author: Neradugomma, Naveen K|Subramaniam, Dharmalingam|Tawfik, Ossama W|Goffin, Vincent|Kumar, T Rajendra|Jensen, Roy A|Anant, Shrikant
PMID: 24265293
Journal: Int J Cancer. 2014 Feb 1;134(3):519-29.
Title: Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer.
Author: Moon, Chang Mo|Kwon, Ji-Hee|Kim, Ji Suk|Oh, Sun-Hee|Jin Lee, Kyoung|Park, Jae Jun|Pil Hong, Sung|Cheon, Jae Hee|Kim, Tae Il|Kim, Won Ho
PMID: 23852449
Journal: Sci Rep. 2014 Feb 4;4:3963.
Title: Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer.
Author: Gao, Fei|Zhang, YuQin|Wang, ShengChun|Liu, YuanQiang|Zheng, Lin|Yang, JianQuan|Huang, Wei|Ye, YanFen|Luo, WeiRen|Xiao, Dong
PMID: 24492635
Journal: Oncogene. 2015 Jul 23;34(30):3935-3945.
Title: Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling.
Author: Mo, Pingli|Zhou, Qiling|Guan, Lei|Wang, Yi|Wang, Wei|Miao, Mengmeng|Tong, Zhangwei|Li, Ming|Majaz, Sidra|Liu, Yonghong|Su, Guoqiang|Xu, Jianming|Yu, Chundong
PMID: 25263446
Journal: J Cell Mol Med. 2015 Jan;19(1):74-81.
Title: Hypothesis: cell signalling influences age-related risk of colorectal cancer.
Author: Bordonaro, Michael|Lazarova, Darina L
PMID: 25388238
Journal: Clin Exp Metastasis. 2015 Feb;32(2):169-79.
Title: HES1 promotes metastasis and predicts poor survival in patients with colorectal cancer.
Author: Yuan, Ruixue|Ke, Jia|Sun, Lei|He, Zhen|Zou, Yifeng|He, Xiaosheng|Chen, Yufeng|Wu, Xianrui|Cai, Zerong|Wang, Lei|Wang, Jianping|Fan, Xinjuan|Wu, Xiaojian|Lan, Ping
PMID: 25636905
Journal: Oncotarget. 2015 Nov 17;6(36):38667-80.
Title: Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3beta pathway in human colon cancer.
Author: Gao, Fei|Huang, Wei|Zhang, YuQin|Tang, ShaoHui|Zheng, Lin|Ma, Feng|Wang, YiMing|Tang, Hui|Li, Xin
PMID: 26452029
Journal: PLoS One. 2015 Dec 9;10(12):e0144322.
Title: Hes1 Increases the Invasion Ability of Colorectal Cancer Cells via the STAT3-MMP14 Pathway.
Author: Weng, M T|Tsao, P N|Lin, H L|Tung, C C|Change, M C|Chang, Y T|Wong, J M|Wei, S C
PMID: 26650241
Journal: Oncol Rep. 2016 Jan;35(1):511-7.
Title: Pien Tze Huang inhibits the proliferation, and induces the apoptosis and differentiation of colorectal cancer stem cells via suppression of the Notch1 pathway.
Author: Qi, Fei|Wei, Lihui|Shen, Aling|Chen, Youqin|Lin, Jiumao|Chu, Jianfeng|Cai, Qiaoyan|Pan, Jie|Peng, Jun
PMID: 26530025
Journal: Hum Pathol. 2016 Nov;57:91-97.
Title: Loss of Hes1 expression is associated with poor prognosis in colorectal adenocarcinoma.
Author: Ahadi, Mahsa|Andrici, Juliana|Sioson, Loretta|Sheen, Amy|Clarkson, Adele|Gill, Anthony J
PMID: 27476040
Journal: Cell Signal. 2016 Aug;28(8):1105-13.
Title: Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1.
Author: Lee, Jennifer|Katzenmaier, Eva-Maria|Kopitz, Jurgen|Gebert, Johannes
PMID: 27156840
Journal: Carcinogenesis. 2016 Apr;37(4):385-96.
Title: An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis.
Author: Ahmed, Ishfaq|Roy, Badal C|Subramaniam, Dharmalingam|Ganie, Showkat Ahmad|Kwatra, Deep|Dixon, Dan|Anant, Shrikant|Zargar, Mohammad Afzal|Umar, Shahid
PMID: 26785732
Journal: World J Surg Oncol. 2016 Jan 14;14(1):10.
Title: Deciphering the anti-angiogenic effect of endostatin/cyclophosphamide to normalize tumor micrangium through notch signaling pathway in colon cancer.
Author: Lv, Jin-Yan|Hu, Tai-Yuan|Wang, Ruo-Yu|Zhu, Jin-Ming|Wang, Gang
PMID: 26762567
Journal: J Cell Physiol. 2016 May;231(5):1097-105.
Title: Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells.
Author: Mirone, Giovanna|Perna, Stefania|Shukla, Arvind|Marfe, Gabriella
PMID: 26419617
Journal: Oncotarget. 2017 Jan 3;8(1):552-564.
Title: Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
Author: Buchberger, Elisabeth|Payrhuber, Dietmar|El Harchi, Miriam|Zagrapan, Branislav|Scheuba, Katharina|Zommer, Anna|Bugyik, Edina|Dome, Balazs|Kral, Julia Barbara|Schrottmaier, Waltraud Cornelia|Schabbauer, Gernot|Petzelbauer, Peter|Groger, Marion|Bilban, Mart
PMID: 27880939
Journal: Onco Targets Ther. 2017 Dec 8;10:5827-5834.
Title: The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer.
Author: Wu, Yinfang|Gong, Lijie|Xu, Ji|Mou, Yiping|Xu, Xiaowu|Qian, Zhenyuan
PMID: 29263679
Journal: J Cancer. 2017 Aug 23;8(14):2802-2808.
Title: HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins.
Author: Sun, Lei|Ke, Jia|He, Zhen|Chen, Zexian|Huang, Qinghua|Ai, Wenjia|Wang, Guoqiang|Wei, Yisheng|Zou, Xiangcai|Zhang, Shi|Lan, Ping|Hong, Chuyuan
PMID: 28928869
Journal: Cancer Res. 2017 Oct 15;77(20):5464-5478.
Title: STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.
Author: Jin, Lin|Vu, Trung|Yuan, Guandou|Datta, Pran K
PMID: 28827371
Journal: Anticancer Drugs. 2017 Jun;28(5):531-539.
Title: Metformin depresses overactivated Notch1/Hes1 signaling in colorectal cancer patients with type 2 diabetes mellitus.
Author: Yang, Bin|Huang, Can-Ze|Yu, Tao|Zhou, Sheng-Ning|Liu, Qi|Liu, Gao-Jie|Chen, Shuang|Han, Fang-Hai
PMID: 28177944
Journal: BMC Cancer. 2017 Jan 13;17(1):50.
Title: Delta-like 4/Notch signaling promotes Apc (Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms.
Author: Badenes, Marina|Trindade, Alexandre|Pissarra, Hugo|Lopes-da-Costa, Luis|Duarte, Antonio
PMID: 28086833
Journal: Gastroenterology. 2017 Jan;152(1):193-205.e10.
Title: Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.
Author: Wang, Yiwei|Huang, Dan|Chen, Kai-Yuan|Cui, Min|Wang, Weihuan|Huang, Xiaoran|Awadellah, Amad|Li, Qing|Friedman, Ann|Xin, William W|Di Martino, Luca|Cominelli, Fabio|Miron, Alex|Chan, Ricky|Fox, James G|Xu, Yan|Shen, Xiling|Kalady, Mathew F|Markowitz, Sanfo
PMID: 27639802
Journal: Biomed Pharmacother. 2018 Jan;97:535-542.
Title: Notch signaling pathway dampens tumor-infiltrating CD8(+) T cells activity in patients with colorectal carcinoma.
Author: Yu, Weifeng|Wang, Yanjun|Guo, Peng
PMID: 29096354
Journal: Eur J Pharmacol. 2018 Jan 5;818:364-370.
Title: Inhibition of Notch1/Hes1 signaling pathway improves radiosensitivity of colorectal cancer cells.
Author: Zhang, Hongzhi|Jiang, Huijuan|Chen, Lei|Liu, Juncai|Hu, Xigang|Zhang, Huixiang
PMID: 29126793
Journal: Oncol Lett. 2018 Feb;15(2):1861-1868.
Title: lncRNA FAM83H-AS1 is associated with the prognosis of colorectal carcinoma and promotes cell proliferation by targeting the Notch signaling pathway.
Author: Lu, Song|Dong, Wei|Zhao, Pei|Liu, Zhenjun
PMID: 29434883
Journal: Oncol Rep. 2018 Apr;39(4):1930-1938.
Title: Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals.
Author: Park, Joo-Hung|Lee, Jeong-Min|Lee, Eun-Jin|Kim, Da-Jeong|Hwang, Won-Bhin
PMID: 29436668
Journal: Sci Rep. 2018 Feb 16;8(1):3161.
Title: Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations.
Author: Druliner, Brooke R|Wang, Panwen|Bae, Taejeong|Baheti, Saurabh|Slettedahl, Seth|Mahoney, Douglas|Vasmatzis, Nikolaos|Xu, Hang|Kim, Minsoo|Bockol, Matthew|O'Brien, Daniel|Grill, Diane|Warner, Nathaniel|Munoz-Gomez, Miguel|Kossick, Kimberlee|Johnson, Ruth|Mo
PMID: 29453410
Journal: Evid Based Complement Alternat Med. 2018 Jan 28;2018:2305683.
Title: Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT.
Author: Wang, Wei|Liu, Mingxing|Wang, Yang|Yang, Tao|Li, Dongsheng|Ding, Feng|Sun, Hongzhi|Bai, Guang|Li, Qing
PMID: 29619065
Journal: J Cell Biochem. 2018 Jul;119(7):5913-5920.
Title: Significance of Notch and Wnt signaling for chemoresistance of colorectal cancer cells HCT116.
Author: Kukcinaviciute, Egle|Jonusiene, Violeta|Sasnauskiene, Ausra|Dabkeviciene, Daiva|Eidenaite, Eigile|Laurinavicius, Arvydas
PMID: 29637602
Journal: PLoS One. 2018 Jun 7;13(6):e0198099.
Title: Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer.
Author: Jarzabek, Monika A|Proctor, William R|Vogt, Jennifer|Desai, Rupal|Dicker, Patrick|Cain, Gary|Raja, Rajiv|Brodbeck, Jens|Stevens, Dale|van der Stok, Eric P|Martens, John W M|Verhoef, Cornelis|Hegde, Priti S|Byrne, Annette T|Tarrant, Jacqueline M
PMID: 29879147
Journal: Int J Cancer. 2018 Jul 7.
Title: Modification of alpha2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Author: Yuan, Qingmin|Chen, Xixi|Han, Yang|Lei, Ting|Wu, Qiang|Yu, Xiao|Wang, Liping|Fan, Zhe|Wang, Shujing
PMID: 29981167