Primary Site >> Colorectal Cancer

Gene >> HDAC8

Journal: Cell Growth Differ. 1990 Dec;1(12):617-26.
Title: Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation.
Author: Hafez, M M|Infante, D|Winawer, S|Friedman, E
PMID: 2288877
Journal: Int J Cancer. 1995 Jun 9;61(6):848-53.
Title: Colon goblet cells lose proliferative response to TGF alpha as they differentiate.
Author: Sauma, S|Huang, F|Winawer, S|Friedman, E
PMID: 7790121
Journal: J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15.
Title: Identification of novel isoform-selective inhibitors within class I histone deacetylases.
Author: Hu, Erding|Dul, Edward|Sung, Chiu-Mei|Chen, Zunxuan|Kirkpatrick, Robert|Zhang, Gui-Feng|Johanson, Kyung|Liu, Ronggang|Lago, Amparo|Hofmann, Glenn|Macarron, Ricardo|de los Frailes, Maite|Perez, Paloma|Krawiec, John|Winkler, James|Jaye, Michael
PMID: 12975486
Journal: Mol Cancer Ther. 2006 May;5(5):1309-17.
Title: CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
Author: Buggy, Joseph J|Cao, Z Alexander|Bass, Kathryn E|Verner, Erik|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian E|Young, Peter R|Dalrymple, Stacie A
PMID: 16731764
Journal: Mol Cancer Ther. 2006 Jul;5(7):1693-701.
Title: CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo.
Author: Cao, Z Alexander|Bass, Kathryn E|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian|Verner, Erik|Dai, Yuqin|Molina, Rafael A|Davis, Jack R|Misialek, Shawn|Sendzik, Martin|Orr, Christine J|Leung, Ling|Callan, Ondine|Young, Peter|Dalrymple, Stacie A|Buggy, J
PMID: 16891455
Journal: Carcinogenesis. 2008 Sep;29(9):1816-24.
Title: Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
Author: Nian, Hui|Delage, Barbara|Pinto, John T|Dashwood, Roderick H
PMID: 18628250
Journal: Carcinogenesis. 2009 Aug;30(8):1416-23.
Title: Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells.
Author: Nian, Hui|Bisson, William H|Dashwood, Wan-Mohaiza|Pinto, John T|Dashwood, Roderick H
PMID: 19528666
Journal: Cancer Res. 2010 Jan 15;70(2):646-54.
Title: Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.
Author: Li, Yongming|Li, Xia|Guo, Bin
PMID: 20068155
Journal: World J Gastroenterol. 2011 Nov 14;17(42):4711-7.
Title: miR-93 suppresses proliferation and colony formation of human colon cancer stem cells.
Author: Yu, Xiao-Feng|Zou, Jian|Bao, Zhi-Jun|Dong, Jie
PMID: 22180714
Journal: Eur J Med Chem. 2014 Oct 30;86:528-41.
Title: Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups.
Author: Bhansali, Pravin|Hanigan, Christin L|Perera, Lalith|Casero, Robert A Jr|Tillekeratne, L M Viranga
PMID: 25203782
Journal: Cell Death Dis. 2014 Oct 16;5:e1476.
Title: HDAC8 and STAT3 repress BMF gene activity in colon cancer cells.
Author: Kang, Y|Nian, H|Rajendran, P|Kim, E|Dashwood, W M|Pinto, J T|Boardman, L A|Thibodeau, S N|Limburg, P J|Lohr, C V|Bisson, W H|Williams, D E|Ho, E|Dashwood, R H
PMID: 25321483
Journal: Pharmacogn Mag. 2015 Oct;11(Suppl 4):S564-9.
Title: In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and its Isolated Compounds.
Author: Mira, Amira|Shimizu, Kuniyoshi
PMID: 27013795