Primary Site >> Colorectal Cancer
Gene >> HDAC8
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Ref: Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation. PMID: 2288877 |
Ref: Colon goblet cells lose proliferative response to TGF alpha as they differentiate. PMID: 7790121 |
Ref: Identification of novel isoform-selective inhibitors within class I histone deacetylases. PMID: 12975486 |
Ref: CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo. PMID: 16731764 Ref: CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo. PMID: 16891455 |
Ref: Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. PMID: 18628250 |
Ref: Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. PMID: 19528666 |
Ref: Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases. PMID: 20068155 |
Ref: miR-93 suppresses proliferation and colony formation of human colon cancer stem cells. PMID: 22180714 |
Ref: Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups. PMID: 25203782 Ref: HDAC8 and STAT3 repress BMF gene activity in colon cancer cells. PMID: 25321483 |
Ref: In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and its Isolated Compounds. PMID: 27013795 |