Primary Site >> Colorectal Cancer

Gene >> HDAC4

Journal: Cell Growth Differ. 1990 Dec;1(12):617-26.
Title: Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation.
Author: Hafez, M M|Infante, D|Winawer, S|Friedman, E
PMID: 2288877
Journal: Oncol Rep. 2006 Sep;16(3):603-8.
Title: New p53 related genes in human tumors: significant downregulation in colon and lung carcinomas.
Author: LLeonart, M E|Vidal, F|Gallardo, D|Diaz-Fuertes, M|Rojo, F|Cuatrecasas, M|Lopez-Vicente, L|Kondoh, H|Blanco, C|Carnero, A|Ramon y Cajal, S
PMID: 16865262
Journal: Mol Biol Cell. 2008 Oct;19(10):4062-75.
Title: HDAC4 promotes growth of colon cancer cells via repression of p21.
Author: Wilson, Andrew J|Byun, Do-Sun|Nasser, Shannon|Murray, Lucas B|Ayyanar, Kanyalakshmi|Arango, Diego|Figueroa, Maria|Melnick, Ari|Kao, Gary D|Augenlicht, Leonard H|Mariadason, John M
PMID: 18632985
Journal: Oncogene. 2009 Nov 19;28(46):4065-74.
Title: Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells.
Author: Song, B|Wang, Y|Xi, Y|Kudo, K|Bruheim, S|Botchkina, G I|Gavin, E|Wan, Y|Formentini, A|Kornmann, M|Fodstad, O|Ju, J
PMID: 19734943
Journal: Pathol Oncol Res. 2012 Jul;18(3):713-20.
Title: SAHA inhibits the growth of colon tumors by decreasing histone deacetylase and the expression of cyclin D1 and survivin.
Author: Jin, Jong-Shiaw|Tsao, Tang-Yi|Sun, Pei-Chang|Yu, Cheng-Ping|Tzao, Ching
PMID: 22270866
Journal: Cancer Res. 2013 Feb 15;73(4):1386-99.
Title: Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment.
Author: Isaacs, John T|Antony, Lizamma|Dalrymple, Susan L|Brennen, W Nathaniel|Gerber, Stephanie|Hammers, Hans|Wissing, Michel|Kachhap, Sushant|Luo, Jun|Xing, Li|Bjork, Per|Olsson, Anders|Bjork, Anders|Leanderson, Tomas
PMID: 23149916
Journal: Cell Oncol (Dordr). 2013 Apr;36(2):155-67.
Title: Epigenetic control of HNF-4alpha in colon carcinoma cells affects MUC4 expression and malignancy.
Author: Algamas-Dimantov, Anna|Yehuda-Shnaidman, Einav|Peri, Irena|Schwartz, Betty
PMID: 23307400
Journal: Evid Based Complement Alternat Med. 2013;2013:541695.
Title: Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer.
Author: Chen, Chun-Chieh|Sureshbabul, Munisamy|Chen, Huei-Wen|Lin, Yu-Shuang|Lee, Jen-Yi|Hong, Qi-Sheng|Yang, Ya-Chien|Yu, Sung-Liang
PMID: 23970932
Journal: Biochem Pharmacol. 2015 Mar 15;94(2):69-78.
Title: Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1.
Author: Guo, Yue|Shu, Limin|Zhang, Chengyue|Su, Zheng-Yuan|Kong, Ah-Ng Tony
PMID: 25640947
Journal: Anticancer Res. 2015 Feb;35(2):645-51.
Title: Potential anticancer properties and mechanisms of action of curcumin.
Author: Vallianou, Natalia G|Evangelopoulos, Angelos|Schizas, Nikos|Kazazis, Christos
PMID: 25667441
Journal: J Pineal Res. 2015 May;58(4):429-38.
Title: Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation.
Author: Wei, Jia-Yi|Li, Wan-Ming|Zhou, Lin-Lin|Lu, Qiu-Nan|He, Wei
PMID: 25752481
Journal: Sci Rep. 2015 Oct 29;5:15900.
Title: The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
Author: Huang, Yu-Han|Huang, Shiu-Wen|Hsu, Ya-Fen|Ou, George|Huang, Wei-Jan|Hsu, Ming-Jen
PMID: 26510776
Journal: Oncotarget. 2017 Sep 23;8(50):87718-87736.
Title: HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation.
Author: Ahmad, Rizwan|Kumar, Balawant|Pan, Kaichao|Dhawan, Punita|Singh, Amar B
PMID: 29152115
Journal: FASEB J. 2018 Sep 25:fj201801390R.
Title: RARbeta acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.
Author: Hu, Ying|French, Samuel W|Chau, Thinh|Liu, Hui-Xin|Sheng, Lili|Wei, Fang|Stondell, Jesse|Garcia, Juan C|Du, Yanlei|Bowlus, Christopher L|Wan, Yu-Jui Yvonne
PMID: 30252536
Journal: Clin Epigenetics. 2018 Sep 26;10(1):120.
Title: CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.
Author: Graule, Janina|Uth, Kristin|Fischer, Elia|Centeno, Irene|Galvan, Jose A|Eichmann, Micha|Rau, Tilman T|Langer, Rupert|Dawson, Heather|Nitsche, Ulrich|Traeger, Peter|Berger, Martin D|Schnuriger, Beat|Hadrich, Marion|Studer, Peter|Inderbitzin, Daniel|Lugli,
PMID: 30257705