Primary Site >> Colorectal Cancer

Gene >> HDAC3

Journal: Gan. 1984 Nov;75(11):1025-9.
Title: Tumor-associated expression of glycosphingolipid Hanganutziu-Deicher antigen in human cancers.
Author: Higashi, H|Nishi, Y|Fukui, Y|Ikuta, K|Ueda, S|Kato, S|Fujita, M|Nakano, Y|Taguchi, T|Sakai, S
PMID: 6394416
Journal: Cell Growth Differ. 1990 Dec;1(12):617-26.
Title: Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation.
Author: Hafez, M M|Infante, D|Winawer, S|Friedman, E
PMID: 2288877
Journal: Cell Growth Differ. 1994 Mar;5(3):267-75.
Title: Colon carcinoma cells switch their response to transforming growth factor beta 1 with tumor progression.
Author: Hsu, S|Huang, F|Hafez, M|Winawer, S|Friedman, E
PMID: 8018559
Journal: J Biol Chem. 1994 May 6;269(18):13231-7.
Title: Two different signal transduction pathways can be activated by transforming growth factor beta 1 in epithelial cells.
Author: Yan, Z|Winawer, S|Friedman, E
PMID: 8175753
Journal: Cell Growth Differ. 1994 Sep;5(9):909-17.
Title: The role of nm23 in transforming growth factor beta 1-mediated adherence and growth arrest.
Author: Hsu, S|Huang, F|Wang, L|Banerjee, S|Winawer, S|Friedman, E
PMID: 7819128
Journal: Carcinogenesis. 1995 Sep;16(9):2259-62.
Title: Colon carcinoma cells with inactive nm23 show increased motility and response to motility factors.
Author: Hsu, S|Huang, F|Ossowski, L|Friedman, E
PMID: 7554087
Journal: Cell Growth Differ. 1996 May;7(5):587-94.
Title: Protein kinase C beta 1 and protein kinase C beta 2 activate p57 mitogen-activated protein kinase and block differentiation in colon carcinoma cells.
Author: Sauma, S|Yan, Z|Ohno, S|Friedman, E
PMID: 8732668
Journal: J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15.
Title: Identification of novel isoform-selective inhibitors within class I histone deacetylases.
Author: Hu, Erding|Dul, Edward|Sung, Chiu-Mei|Chen, Zunxuan|Kirkpatrick, Robert|Zhang, Gui-Feng|Johanson, Kyung|Liu, Ronggang|Lago, Amparo|Hofmann, Glenn|Macarron, Ricardo|de los Frailes, Maite|Perez, Paloma|Krawiec, John|Winkler, James|Jaye, Michael
PMID: 12975486
Journal: J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3.
Title: Requirement of histone deacetylase activity for signaling by STAT1.
Author: Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard
PMID: 15123634
Journal: Int J Cancer. 2005 Dec 10;117(5):800-6.
Title: Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients.
Author: Shebzukhov, Yuriy V|Koroleva, Ekaterina P|Khlgatian, Svetlana V|Belousov, Pavel V|Kuz'mina, Ksenia E|Radko, Boris V|Longpre, Fanny|Lagarkova, Maria A|Kadachigova, Tatiana S|Gurova, Olga V|Meshcheryakov, Andrey A|Lichinitser, Mikhail R|Knuth, Alexander|Jag
PMID: 15981215
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4287-92.
Title: Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma.
Author: Giannini, Romina|Cavallini, Aldo
PMID: 16309230
Journal: J Biol Chem. 2006 May 12;281(19):13548-58. Epub 2006 Mar 13.
Title: Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.
Author: Wilson, Andrew J|Byun, Do-Sun|Popova, Natalia|Murray, Lucas B|L'Italien, Kaitlin|Sowa, Yoshihiro|Arango, Diego|Velcich, Anna|Augenlicht, Leonard H|Mariadason, John M
PMID: 16533812
Journal: Mol Cancer Ther. 2006 May;5(5):1309-17.
Title: CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
Author: Buggy, Joseph J|Cao, Z Alexander|Bass, Kathryn E|Verner, Erik|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian E|Young, Peter R|Dalrymple, Stacie A
PMID: 16731764
Journal: Mol Cancer Ther. 2006 Jul;5(7):1693-701.
Title: CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo.
Author: Cao, Z Alexander|Bass, Kathryn E|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian|Verner, Erik|Dai, Yuqin|Molina, Rafael A|Davis, Jack R|Misialek, Shawn|Sendzik, Martin|Orr, Christine J|Leung, Ling|Callan, Ondine|Young, Peter|Dalrymple, Stacie A|Buggy, J
PMID: 16891455
Journal: Int J Cancer. 2007 Sep 1;121(5):1138-48.
Title: Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group.
Author: Beckers, Thomas|Burkhardt, Carmen|Wieland, Heike|Gimmnich, Petra|Ciossek, Thomas|Maier, Thomas|Sanders, Karl
PMID: 17455259
Journal: J Biol Chem. 2007 Nov 23;282(47):33994-4002.
Title: Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Author: Evans, Paul M|Zhang, Wen|Chen, Xi|Yang, Jun|Bhakat, Kishor K|Liu, Chunming
PMID: 17908689
Journal: Int J Oncol. 2007 Sep;31(3):633-41.
Title: The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
Author: Fedier, Andre|Dedes, Konstantin J|Imesch, Patrick|Von Bueren, Andre O|Fink, Daniel
PMID: 17671692
Journal: Expert Opin Ther Targets. 2007 Feb;11(2):235-44.
Title: Targeting serum antibody for cancer diagnosis: a focus on colorectal cancer.
Author: Lu, Hailing|Goodell, Vivian|Disis, Mary L
PMID: 17227237
Journal: Mol Carcinog. 2008 Feb;47(2):137-47.
Title: HDAC3 overexpression and colon cancer cell proliferation and differentiation.
Author: Spurling, Colleen C|Godman, Cassandra A|Noonan, Emily J|Rasmussen, Theodore P|Rosenberg, Daniel W|Giardina, Charles
PMID: 17849419
Journal: Clin Cancer Res. 2008 Mar 15;14(6):1669-77.
Title: Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.
Author: Weichert, Wilko|Roske, Annika|Niesporek, Silvia|Noske, Aurelia|Buckendahl, Ann-Christin|Dietel, Manfred|Gekeler, Volker|Boehm, Markus|Beckers, Thomas|Denkert, Carsten
PMID: 18347167
Journal: Mol Biol Cell. 2008 Oct;19(10):4062-75.
Title: HDAC4 promotes growth of colon cancer cells via repression of p21.
Author: Wilson, Andrew J|Byun, Do-Sun|Nasser, Shannon|Murray, Lucas B|Ayyanar, Kanyalakshmi|Arango, Diego|Figueroa, Maria|Melnick, Ari|Kao, Gary D|Augenlicht, Leonard H|Mariadason, John M
PMID: 18632985
Journal: Cancer Biol Ther. 2008 Oct;7(10):1570-80. Epub 2008 Oct 7.
Title: HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling.
Author: Godman, Cassandra A|Joshi, Rashmi|Tierney, Brendan R|Greenspan, Emily|Rasmussen, Theodore P|Wang, Hsin-Wei|Shin, Dong-Guk|Rosenberg, Daniel W|Giardina, Charles
PMID: 18769117
Journal: Biochem J. 2009 Jan 1;417(1):379-89.
Title: Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
Author: Thangaraju, Muthusamy|Carswell, Kristina N|Prasad, Puttur D|Ganapathy, Vadivel
PMID: 18789002
Journal: Autoimmunity. 2009 Feb;42(2):120-5.
Title: Decreased levels of autoantibody against histone deacetylase 3 in patients with systemic sclerosis.
Author: Kuwatsuka, Yutaka|Ogawa, Fumihide|Iwata, Yohei|Komura, Kazuhiro|Muroi, Eiji|Hara, Toshihide|Takenaka, Motoi|Shimizu, Kazuhiro|Hasegawa, Minoru|Fujimoto, Manabu|Sato, Shinichi
PMID: 19021012
Journal: Cancer Res. 2010 Jan 15;70(2):646-54.
Title: Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.
Author: Li, Yongming|Li, Xia|Guo, Bin
PMID: 20068155
Journal: PLoS One. 2011 Mar 25;6(3):e18087.
Title: HDAC inhibition decreases the expression of EGFR in colorectal cancer cells.
Author: Chou, Chia-Wei|Wu, Ming-Shiang|Huang, Wei-Chien|Chen, Ching-Chow
PMID: 21464950
Journal: Mol Cancer. 2011 May 30;10:68.
Title: Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
Author: Rajendran, Praveen|Delage, Barbara|Dashwood, W Mohaiza|Yu, Tian-Wei|Wuth, Bradyn|Williams, David E|Ho, Emily|Dashwood, Roderick H
PMID: 21624135
Journal: Biochim Biophys Acta. 2012 Oct;1821(10):1334-40.
Title: Mechanism and stereoselectivity of HDAC I inhibition by (R)-9-hydroxystearic acid in colon cancer.
Author: Parolin, Carola|Calonghi, Natalia|Presta, Enrica|Boga, Carla|Caruana, Paolo|Naldi, Marina|Andrisano, Vincenza|Masotti, Lanfranco|Sartor, Giorgio
PMID: 22814230
Journal: Pathol Oncol Res. 2012 Jul;18(3):713-20.
Title: SAHA inhibits the growth of colon tumors by decreasing histone deacetylase and the expression of cyclin D1 and survivin.
Author: Jin, Jong-Shiaw|Tsao, Tang-Yi|Sun, Pei-Chang|Yu, Cheng-Ping|Tzao, Ching
PMID: 22270866
Journal: Cancer Res. 2013 Feb 15;73(4):1386-99.
Title: Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment.
Author: Isaacs, John T|Antony, Lizamma|Dalrymple, Susan L|Brennen, W Nathaniel|Gerber, Stephanie|Hammers, Hans|Wissing, Michel|Kachhap, Sushant|Luo, Jun|Xing, Li|Bjork, Per|Olsson, Anders|Bjork, Anders|Leanderson, Tomas
PMID: 23149916
Journal: Cell Oncol (Dordr). 2013 Apr;36(2):155-67.
Title: Epigenetic control of HNF-4alpha in colon carcinoma cells affects MUC4 expression and malignancy.
Author: Algamas-Dimantov, Anna|Yehuda-Shnaidman, Einav|Peri, Irena|Schwartz, Betty
PMID: 23307400
Journal: Mol Cell. 2013 Mar 28;49(6):1083-96.
Title: Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis.
Author: Yang, Fu|Huo, Xi-song|Yuan, Sheng-xian|Zhang, Ling|Zhou, Wei-ping|Wang, Fang|Sun, Shu-han
PMID: 23395002
Journal: Carcinogenesis. 2013 Aug;34(8):1756-63.
Title: DNA methylation and histone modifications of Wnt genes by genistein during colon cancer development.
Author: Zhang, Yukun|Li, Qian|Chen, Hong
PMID: 23598468
Journal: PLoS One. 2013 May 28;8(5):e64600.
Title: HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure.
Author: Stypula-Cyrus, Yolanda|Damania, Dhwanil|Kunte, Dhananjay P|Cruz, Mart Dela|Subramanian, Hariharan|Roy, Hemant K|Backman, Vadim
PMID: 23724067
Journal: Epigenetics. 2013 Jun;8(6):612-23.
Title: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
Author: Rajendran, Praveen|Kidane, Ariam I|Yu, Tian-Wei|Dashwood, Wan-Mohaiza|Bisson, William H|Lohr, Christiane V|Ho, Emily|Williams, David E|Dashwood, Roderick H
PMID: 23770684
Journal: PLoS One. 2013 Jul 16;8(7):e68669.
Title: Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly.
Author: Suzuki, Takayoshi|Kasuya, Yuki|Itoh, Yukihiro|Ota, Yosuke|Zhan, Peng|Asamitsu, Kaori|Nakagawa, Hidehiko|Okamoto, Takashi|Miyata, Naoki
PMID: 23874714
Journal: Anticancer Res. 2013 Dec;33(12):5325-33.
Title: Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
Author: Moseley, Vondina R|Morris, Jay|Knackstedt, Rebecca W|Wargovich, Michael J
PMID: 24324066
Journal: Cancer Biol Ther. 2014 Sep;15(9):1198-207.
Title: The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer.
Author: Wang, Jian|Elahi, Abul|Ajidahun, Abidemi|Clark, Whalen|Hernandez, Jonathan|Achille, Alex|Hao, Ji-hui|Seto, Edward|Shibata, David
PMID: 24919179
Journal: Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15526-31.
Title: Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.
Author: Hamabe, Atsushi|Konno, Masamitsu|Tanuma, Nobuhiro|Shima, Hiroshi|Tsunekuni, Kenta|Kawamoto, Koichi|Nishida, Naohiro|Koseki, Jun|Mimori, Koshi|Gotoh, Noriko|Yamamoto, Hirofumi|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi
PMID: 25313085
Journal: Int J Oncol. 2015 Dec;47(6):2264-75.
Title: Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.
Author: Cacan, Ercan|Greer, Susanna F|Garnett-Benson, Charlie
PMID: 26458736
Journal: Sci Rep. 2015 Oct 29;5:15900.
Title: The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
Author: Huang, Yu-Han|Huang, Shiu-Wen|Hsu, Ya-Fen|Ou, George|Huang, Wei-Jan|Hsu, Ming-Jen
PMID: 26510776
Journal: Clin Epigenetics. 2015 Sep 18;7:102.
Title: Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Author: Rajendran, Praveen|Dashwood, Wan-Mohaiza|Li, Li|Kang, Yuki|Kim, Eunah|Johnson, Gavin|Fischer, Kay A|Lohr, Christiane V|Williams, David E|Ho, Emily|Yamamoto, Masayuki|Lieberman, David A|Dashwood, Roderick H
PMID: 26388957
Journal: Biomed Pharmacother. 2015 Apr;71:70-8.
Title: A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells.
Author: Yang, Liyan|Liang, Qiannan|Shen, Ke|Ma, Li|An, Na|Deng, Weiping|Fei, Zhewei|Liu, Jianwen
PMID: 25960218
Journal: Mol Carcinog. 2015 Nov;54(11):1513-20.
Title: The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses.
Author: Dickinson, Sally E|Rusche, Jadrian J|Bec, Sergiu L|Horn, David J|Janda, Jaroslav|Rim, So Hyun|Smith, Catharine L|Bowden, G Timothy
PMID: 25307283
Journal: Am J Cancer Res. 2016 Feb 15;6(3):664-76. eCollection 2016.
Title: Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro.
Author: Lutz, Lisa|Fitzner, Ingrid Coutino|Ahrens, Theresa|Geissler, Anna-Lena|Makowiec, Frank|Hopt, Ulrich T|Bogatyreva, Lioudmila|Hauschke, Dieter|Werner, Martin|Lassmann, Silke
PMID: 27152243
Journal: Cancer Res. 2016 Dec 15;76(24):7277-7289.
Title: CBX4 Suppresses Metastasis via Recruitment of HDAC3 to the Runx2 Promoter in Colorectal Carcinoma.
Author: Wang, Xin|Li, Liping|Wu, Yuanzhong|Zhang, Ruhua|Zhang, Meifang|Liao, Dan|Wang, Gang|Qin, Ge|Xu, Rui-Hua|Kang, Tiebang
PMID: 27864346
Journal: Contemp Oncol (Pozn). 2016;20(6):458-462.
Title: Increased transforming growth factor beta and interleukin 10 transcripts in peripheral blood mononuclear cells of colorectal cancer patients.
Author: Stanilov, Noyko S|Miteva, Lyuba|Cirovski, Geo|Stanilova, Spaska A
PMID: 28239283
Journal: J Steroid Biochem Mol Biol. 2017 Apr;168:49-59.
Title: Colonic transcriptional response to 1alpha,25(OH)2 vitamin D3 in African- and European-Americans.
Author: Alleyne, Dereck|Witonsky, David B|Mapes, Brandon|Nakagome, Shigeki|Sommars, Meredith|Hong, Ellie|Muckala, Katy A|Di Rienzo, Anna|Kupfer, Sonia S
PMID: 28163244
Journal: BMC Cancer. 2017 Feb 21;17(1):148.
Title: WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice.
Author: Singh, Vijay Pratap|Katta, Saritha|Kumar, Satish
PMID: 28222755
Journal: Eur J Med Chem. 2017 Jul 7;134:185-206.
Title: Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.
Author: Li, Xiaoyang|Zhang, Yingjie|Jiang, Yuqi|Wu, Jingde|Inks, Elizabeth S|Chou, C James|Gao, Shuai|Hou, Jinning|Ding, Qinge|Li, Jingyao|Wang, Xue|Huang, Yongxue|Xu, Wenfang
PMID: 28415009
Journal: Cell Death Dis. 2017 Jul 27;8(7):e2958.
Title: miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer.
Author: Guo, Xiaofeng|Zhu, Yuekun|Hong, Xinya|Zhang, Mukun|Qiu, Xingfeng|Wang, Zhenfa|Qi, Zhongquan|Hong, Xuehui
PMID: 28749470
Journal: J Pharmacol Sci. 2017 Dec;135(4):148-155.
Title: Butyrate suppresses motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner.
Author: Li, Qingran|Ding, Chujie|Meng, Tuo|Lu, Wenjie|Liu, Wenyue|Hao, Haiping|Cao, Lijuan
PMID: 29233468
Journal: Int J Oncol. 2018 Apr;52(4):1305-1316.
Title: Upregulation of AKAP12 with HDAC3 depletion suppresses the progression and migration of colorectal cancer.
Author: He, Ping|Li, Ke|Li, Shi-Bao|Hu, Ting-Ting|Guan, Ming|Sun, Fen-Yong|Liu, Wei-Wei
PMID: 29484387
Journal: Adv Clin Exp Med. 2018 Mar;27(3):305-311.
Title: Deregulated expression of HDAC3 in colorectal cancer and its clinical significance.
Author: Nemati, Masoumeh|Ajami, Naser|Estiar, Mehrdad Asghari|Rezapour, Saleheh|Gavgani, Reyhaneh Ravanbakhsh|Hashemzadeh, Shahryar|Kafil, Hossein Samadi|Sakhinia, Ebrahim
PMID: 29558042
Journal: Mol Nutr Food Res. 2018 Sep;62(18):e1800228.
Title: Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs.
Author: Okonkwo, Adaobi|Mitra, Joy|Johnson, Gavin S|Li, Li|Dashwood, Wan Mohaiza|Hegde, Muralidhar L|Yue, Chen|Dashwood, Roderick H|Rajendran, Praveen
PMID: 29924908
Journal: Int J Oncol. 2018 Oct;53(4):1469-1480.
Title: Upregulation of PDL1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300mediated NFkappaB signaling.
Author: Lucas, Justin|Hsieh, Tze-Chen|Halicka, H Dorota|Darzynkiewicz, Zbigniew|Wu, Joseph M
PMID: 30066852