Primary Site >> Colorectal Cancer

Gene >> HDAC1

Journal: Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6791-6.
Title: p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells.
Author: Archer, S Y|Meng, S|Shei, A|Hodin, R A
PMID: 9618491
Journal: J Biol Chem. 2002 Jul 5;277(27):24258-64. Epub 2002 May 1.
Title: Lymphoid enhancer factor-1 blocks adenomatous polyposis coli-mediated nuclear export and degradation of beta-catenin. Regulation by histone deacetylase 1.
Author: Henderson, Beric R|Galea, Melanie|Schuechner, Stefan|Leung, Louie
PMID: 11986304
Journal: Nucleic Acids Res. 2003 Mar 15;31(6):1693-703.
Title: Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site.
Author: Camarero, Nuria|Nadal, Alicia|Barrero, Maria Jose|Haro, Diego|Marrero, Pedro F
PMID: 12626711
Journal: J Biol Chem. 2003 Sep 19;278(38):36496-504. Epub 2003 Jul 7.
Title: Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Author: Di Padova, Monica|Bruno, Tiziana|De Nicola, Francesca|Iezzi, Simona|D'Angelo, Carmen|Gallo, Rita|Nicosia, Daniela|Corbi, Nicoletta|Biroccio, Annamaria|Floridi, Aristide|Passananti, Claudio|Fanciulli, Maurizio
PMID: 12847090
Journal: J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15.
Title: Identification of novel isoform-selective inhibitors within class I histone deacetylases.
Author: Hu, Erding|Dul, Edward|Sung, Chiu-Mei|Chen, Zunxuan|Kirkpatrick, Robert|Zhang, Gui-Feng|Johanson, Kyung|Liu, Ronggang|Lago, Amparo|Hofmann, Glenn|Macarron, Ricardo|de los Frailes, Maite|Perez, Paloma|Krawiec, John|Winkler, James|Jaye, Michael
PMID: 12975486
Journal: J Nutr. 2004 Apr;134(4):792-8.
Title: Kruppel-like factor 4 is transactivated by butyrate in colon cancer cells.
Author: Chen, Zhi Yi|Rex, Sybille|Tseng, Chi-Chuan
PMID: 15051827
Journal: J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3.
Title: Requirement of histone deacetylase activity for signaling by STAT1.
Author: Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard
PMID: 15123634
Journal: Ann Oncol. 2004 Jul;15(7):1079-85.
Title: Solid tumors in patients treated for Hodgkin's disease: a report from the German Hodgkin Lymphoma Study Group.
Author: Behringer, K|Josting, A|Schiller, P|Eich, H T|Bredenfeld, H|Diehl, V|Engert, A
PMID: 15205202
Journal: Cell Death Differ. 2005 Apr;12(4):395-404.
Title: Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1.
Author: Huang, B H|Laban, M|Leung, C H-W|Lee, L|Lee, C K|Salto-Tellez, M|Raju, G C|Hooi, S C
PMID: 15665816
Journal: J Lipid Res. 2005 Aug;46(8):1596-603. Epub 2005 Feb 16.
Title: Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer.
Author: Calonghi, Natalia|Cappadone, Concettina|Pagnotta, Eleonora|Boga, Carla|Bertucci, Carlo|Fiori, Jessica|Tasco, Gianluca|Casadio, Rita|Masotti, Lanfranco
PMID: 15716589
Journal: Eur J Surg Oncol. 2005 May;31(4):376-80.
Title: Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases.
Author: Mimori, K|Ogawa, K|Okamoto, M|Sudo, T|Inoue, H|Mori, M
PMID: 15837043
Journal: Hum Pathol. 2005 Apr;36(4):364-71.
Title: Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma.
Author: Chang, Hee Jin|Jung, Kyung Hae|Kim, Dae Yong|Jeong, Seung-Yong|Choi, Hyo Seong|Kim, Young Hoon|Sohn, Dae Kyung|Yoo, Byong Chul|Lim, Seok-Byung|Kim, Dae-Hyun|Ahn, Joong-Bae|Kim, Il-Jin|Kim, Jin Man|Yoon, Wan-Hee|Park, Jae-Gahb
PMID: 15891997
Journal: Int J Cancer. 2005 Dec 10;117(5):800-6.
Title: Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients.
Author: Shebzukhov, Yuriy V|Koroleva, Ekaterina P|Khlgatian, Svetlana V|Belousov, Pavel V|Kuz'mina, Ksenia E|Radko, Boris V|Longpre, Fanny|Lagarkova, Maria A|Kadachigova, Tatiana S|Gurova, Olga V|Meshcheryakov, Andrey A|Lichinitser, Mikhail R|Knuth, Alexander|Jag
PMID: 15981215
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4287-92.
Title: Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma.
Author: Giannini, Romina|Cavallini, Aldo
PMID: 16309230
Journal: Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):735-41.
Title: Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells.
Author: D'Orazi, Gabriella|Sciulli, Maria Gina|Di Stefano, Valeria|Riccioni, Sabrina|Frattini, Milo|Falcioni, Rita|Bertario, Lucio|Sacchi, Ada|Patrignani, Paola
PMID: 16467083
Journal: Biochem Biophys Res Commun. 2006 Apr 7;342(2):585-8. Epub 2006 Feb 10.
Title: 9-Hydroxystearic acid interferes with EGF signalling in a human colon adenocarcinoma.
Author: Calonghi, Natalia|Pagnotta, Eleonora|Parolin, Carola|Tognoli, Cristina|Boga, Carla|Masotti, Lanfranco
PMID: 16487928
Journal: Genes Dev. 2006 Mar 1;20(5):586-600.
Title: The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
Author: Sierra, Jose|Yoshida, Tomonori|Joazeiro, Claudio A|Jones, Katherine A
PMID: 16510874
Journal: J Biol Chem. 2006 May 12;281(19):13548-58. Epub 2006 Mar 13.
Title: Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.
Author: Wilson, Andrew J|Byun, Do-Sun|Popova, Natalia|Murray, Lucas B|L'Italien, Kaitlin|Sowa, Yoshihiro|Arango, Diego|Velcich, Anna|Augenlicht, Leonard H|Mariadason, John M
PMID: 16533812
Journal: Anticancer Drugs. 2006 Jun;17(5):521-6.
Title: N-methylformamide and 9-hydroxystearic acid: two anti-proliferative and differentiating agents with different modes of action in colon cancer cells.
Author: Pagnotta, Eleonora|Calonghi, Natalia|Boga, Carla|Masotti, Lanfranco
PMID: 16702808
Journal: Mol Cancer Ther. 2006 May;5(5):1309-17.
Title: CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
Author: Buggy, Joseph J|Cao, Z Alexander|Bass, Kathryn E|Verner, Erik|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian E|Young, Peter R|Dalrymple, Stacie A
PMID: 16731764
Journal: Mol Cancer Ther. 2006 Jul;5(7):1693-701.
Title: CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo.
Author: Cao, Z Alexander|Bass, Kathryn E|Balasubramanian, Sriram|Liu, Liang|Schultz, Brian|Verner, Erik|Dai, Yuqin|Molina, Rafael A|Davis, Jack R|Misialek, Shawn|Sendzik, Martin|Orr, Christine J|Leung, Ling|Callan, Ondine|Young, Peter|Dalrymple, Stacie A|Buggy, J
PMID: 16891455
Journal: Int J Cancer. 2007 Sep 1;121(5):1138-48.
Title: Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group.
Author: Beckers, Thomas|Burkhardt, Carmen|Wieland, Heike|Gimmnich, Petra|Ciossek, Thomas|Maier, Thomas|Sanders, Karl
PMID: 17455259
Journal: Exp Mol Med. 2007 Apr 30;39(2):195-204.
Title: Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells.
Author: Park, Hye-Young|Jeon, Yoon-Kyung|Shin, Hyun-Jin|Kim, Il-Jin|Kang, Hio-Chung|Jeong, Sook-Jung|Chung, Doo-Hyun|Lee, Chang-Woo
PMID: 17464181
Journal: Int J Oncol. 2007 Sep;31(3):633-41.
Title: The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
Author: Fedier, Andre|Dedes, Konstantin J|Imesch, Patrick|Von Bueren, Andre O|Fink, Daniel
PMID: 17671692
Journal: J Clin Pathol. 2007 Nov;60(11):1205-10. Epub 2007 Aug 24.
Title: Expression of HDAC1 and CBP/p300 in human colorectal carcinomas.
Author: Ishihama, Katsuyoshi|Yamakawa, Mitsunori|Semba, Shuho|Takeda, Hiroaki|Kawata, Sumio|Kimura, Seishi|Kimura, Wataru
PMID: 17720775
Journal: Br J Cancer. 2007 Nov 19;97(10):1344-53.
Title: R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies.
Author: Arts, J|Angibaud, P|Marien, A|Floren, W|Janssens, B|King, P|van Dun, J|Janssen, L|Geerts, T|Tuman, R W|Johnson, D L|Andries, L|Jung, M|Janicot, M|van Emelen, K
PMID: 18000499
Journal: Cancer Biol Ther. 2007 Oct;6(10):1606-13. Epub 2007 Jul 13.
Title: Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?
Author: Mazzarelli, Paola|Pucci, Sabina|Bonanno, Elena|Sesti, Fabiola|Calvani, Menotti|Spagnoli, Luigi Giusto
PMID: 18253084
Journal: Mol Carcinog. 2008 Feb;47(2):137-47.
Title: HDAC3 overexpression and colon cancer cell proliferation and differentiation.
Author: Spurling, Colleen C|Godman, Cassandra A|Noonan, Emily J|Rasmussen, Theodore P|Rosenberg, Daniel W|Giardina, Charles
PMID: 17849419
Journal: Clin Cancer Res. 2008 Mar 15;14(6):1669-77.
Title: Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.
Author: Weichert, Wilko|Roske, Annika|Niesporek, Silvia|Noske, Aurelia|Buckendahl, Ann-Christin|Dietel, Manfred|Gekeler, Volker|Boehm, Markus|Beckers, Thomas|Denkert, Carsten
PMID: 18347167
Journal: Br J Cancer. 2008 May 6;98(9):1515-24.
Title: Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.
Author: Calcagno, A M|Fostel, J M|To, K K W|Salcido, C D|Martin, S E|Chewning, K J|Wu, C-P|Varticovski, L|Bates, S E|Caplen, N J|Ambudkar, S V
PMID: 18382425
Journal: J Cell Mol Med. 2008 Apr;12(2):607-21.
Title: Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.
Author: Habold, C|Poehlmann, A|Bajbouj, K|Hartig, R|Korkmaz, K S|Roessner, A|Schneider-Stock, R
PMID: 18419600
Journal: Clin Exp Metastasis. 2008;25(7):703-16.
Title: Histone deacetylase inhibitors: the anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex).
Author: Tarasenko, Nataly|Nudelman, Abraham|Tarasenko, Igor|Entin-Meer, Michal|Hass-Kogan, Daphne|Inbal, Aida|Rephaeli, Ada
PMID: 18506586
Journal: Nutr Cancer. 2008;60(5):692-702.
Title: The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells.
Author: Spurling, Colleen C|Suhl, Joshua A|Boucher, Nathalie|Nelson, Craig E|Rosenberg, Daniel W|Giardina, Charles
PMID: 18791934
Journal: J Proteome Res. 2008 Dec;7(12):5177-86.
Title: Quantitative analysis of histone deacetylase-1 selective histone modifications by differential mass spectrometry.
Author: Lee, Anita Y H|Paweletz, Cloud P|Pollock, Roy M|Settlage, Robert E|Cruz, Jonathan C|Secrist, J Paul|Miller, Thomas A|Stanton, Matthew G|Kral, Astrid M|Ozerova, Nicole D S|Meng, Fanyu|Yates, Nathan A|Richon, Victoria|Hendrickson, Ronald C
PMID: 19367703
Journal: Biochem J. 2009 Jan 1;417(1):379-89.
Title: Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
Author: Thangaraju, Muthusamy|Carswell, Kristina N|Prasad, Puttur D|Ganapathy, Vadivel
PMID: 18789002
Journal: Autoimmunity. 2009 Feb;42(2):120-5.
Title: Decreased levels of autoantibody against histone deacetylase 3 in patients with systemic sclerosis.
Author: Kuwatsuka, Yutaka|Ogawa, Fumihide|Iwata, Yohei|Komura, Kazuhiro|Muroi, Eiji|Hara, Toshihide|Takenaka, Motoi|Shimizu, Kazuhiro|Hasegawa, Minoru|Fujimoto, Manabu|Sato, Shinichi
PMID: 19021012
Journal: Oncogene. 2009 Mar 26;28(12):1496-505.
Title: 15-LOX-1 transcription suppression through the NuRD complex in colon cancer cells.
Author: Zuo, X|Morris, J S|Broaddus, R|Shureiqi, I
PMID: 19198625
Journal: Cancer Res. 2009 Apr 15;69(8):3597-604.
Title: Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.
Author: Kato, Takuya|Shimono, Yohei|Hasegawa, Masaki|Jijiwa, Mayumi|Enomoto, Atsushi|Asai, Naoya|Murakumo, Yoshiki|Takahashi, Masahide
PMID: 19351825
Journal: Int J Cancer. 2009 Sep 15;125(6):1306-15.
Title: ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.
Author: Kumamoto, Kensuke|Fujita, Kaori|Kurotani, Reiko|Saito, Motonobu|Unoki, Motoko|Hagiwara, Nobutoshi|Shiga, Hideaki|Bowman, Elise D|Yanaihara, Nozomu|Okamura, Shu|Nagashima, Makoto|Miyamoto, Kotaro|Takenoshita, Seiichi|Yokota, Jun|Harris, Curtis C
PMID: 19437536
Journal: Carcinogenesis. 2009 Aug;30(8):1416-23.
Title: Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells.
Author: Nian, Hui|Bisson, William H|Dashwood, Wan-Mohaiza|Pinto, John T|Dashwood, Roderick H
PMID: 19528666
Journal: Clin Cancer Res. 2009 Nov 15;15(22):6841-51.
Title: JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity.
Author: Arts, Janine|King, Peter|Marien, Ann|Floren, Wim|Belien, Ann|Janssen, Lut|Pilatte, Isabelle|Roux, Bruno|Decrane, Laurence|Gilissen, Ron|Hickson, Ian|Vreys, Veronique|Cox, Eugene|Bol, Kees|Talloen, Willem|Goris, Ilse|Andries, Luc|Du Jardin, Marc|Janicot, M
PMID: 19861438
Journal: Cancer Res. 2010 Jan 15;70(2):646-54.
Title: Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.
Author: Li, Yongming|Li, Xia|Guo, Bin
PMID: 20068155
Journal: Bioorg Med Chem Lett. 2010 Jun 1;20(11):3314-21.
Title: Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity.
Author: Wang, Haishan|Lim, Ze-Yi|Zhou, Yan|Ng, Melvin|Lu, Ting|Lee, Ken|Sangthongpitag, Kanda|Goh, Kee Chuan|Wang, Xukun|Wu, Xiaofeng|Khng, Hwee Hoon|Goh, Siok Kun|Ong, Wai Chung|Bonday, Zahid|Sun, Eric T
PMID: 20451378
Journal: Apoptosis. 2010 Dec;15(12):1540-8.
Title: JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative.
Author: Kim, Dong-Myung|Won, Misun|Chung, Chung-Sook|Kim, Semi|Yim, Hyeon Joo|Jung, Sang-Hun|Jeong, ShinWu
PMID: 20683666
Journal: J Pharmacol Exp Ther. 2010 Nov;335(2):351-61.
Title: Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.
Author: Liu, Yanxia|Salvador, Lilibeth A|Byeon, Seongrim|Ying, Yongcheng|Kwan, Jason C|Law, Brian K|Hong, Jiyong|Luesch, Hendrik
PMID: 20739454
Journal: Mol Cancer. 2010 Oct 15;9:275.
Title: Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line.
Author: Waby, Jennifer S|Chirakkal, Haridasan|Yu, ChenWei|Griffiths, Gareth J|Benson, Roderick S P|Bingle, Colin D|Corfe, Bernard M
PMID: 20950428
Journal: Sci Signal. 2010 Nov 2;3(146):ra80.
Title: DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination.
Author: Du, Zhanwen|Song, Jing|Wang, Yong|Zhao, Yiqing|Guda, Kishore|Yang, Shuming|Kao, Hung-Ying|Xu, Yan|Willis, Joseph|Markowitz, Sanford D|Sedwick, David|Ewing, Robert M|Wang, Zhenghe
PMID: 21045206
Journal: PLoS One. 2010 Dec 3;5(12):e14229.
Title: Epigenetic silencing of peroxisome proliferator-activated receptor gamma is a biomarker for colorectal cancer progression and adverse patients' outcome.
Author: Pancione, Massimo|Sabatino, Lina|Fucci, Alessandra|Carafa, Vincenzo|Nebbioso, Angela|Forte, Nicola|Febbraro, Antonio|Parente, Domenico|Ambrosino, Concetta|Normanno, Nicola|Altucci, Lucia|Colantuoni, Vittorio
PMID: 21151932
Journal: Int J Cancer. 2011 Feb 1;128(3):551-61.
Title: DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells.
Author: Zhang, Yu|Gao, Yanyan|Zhang, Guoping|Huang, Shuyan|Dong, Zhixiong|Kong, Chenfei|Su, Dongmei|Du, Juan|Zhu, Shan|Liang, Qian|Zhang, Jianchao|Lu, Jun|Huang, Baiqu
PMID: 20473858
Journal: Mol Cell Proteomics. 2011 Aug;10(8):M111.010462.
Title: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis.
Author: Kaller, Markus|Liffers, Sven-Thorsten|Oeljeklaus, Silke|Kuhlmann, Katja|Roh, Simone|Hoffmann, Reinhard|Warscheid, Bettina|Hermeking, Heiko
PMID: 21566225
Journal: Oncol Rep. 2011 Aug;26(2):343-8.
Title: Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer.
Author: Higashijima, Jun|Kurita, Nobuhiro|Miyatani, Tomohiko|Yoshikawa, Kozo|Morimoto, Shinya|Nishioka, Masanori|Iwata, Takashi|Shimada, Mitsuo
PMID: 21617866
Journal: Bioorg Med Chem Lett. 2011 Aug 15;21(16):4909-12.
Title: The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.
Author: Shultz, Michael|Fan, Jianmei|Chen, Christine|Cho, Young Shin|Davis, Nicole|Bickford, Sheri|Buteau, Kristen|Cao, Xueying|Holmqvist, Mats|Hsu, Meier|Jiang, Lei|Liu, Gang|Lu, Qiang|Patel, Chetan|Suresh, Joghee Raju|Selvaraj, Mannangatti|Urban, Laszlo|Wang, P
PMID: 21742496
Journal: Pathol Oncol Res. 2012 Jul;18(3):713-20.
Title: SAHA inhibits the growth of colon tumors by decreasing histone deacetylase and the expression of cyclin D1 and survivin.
Author: Jin, Jong-Shiaw|Tsao, Tang-Yi|Sun, Pei-Chang|Yu, Cheng-Ping|Tzao, Ching
PMID: 22270866
Journal: Tumour Biol. 2012 Apr;33(2):403-12.
Title: Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3.
Author: Kang, Kyoung Ah|Zhang, Rui|Kim, Gi Young|Bae, Suk Chul|Hyun, Jin Won
PMID: 22274925
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1405-15.
Title: Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.
Author: Zimmerman, Mary A|Singh, Nagendra|Martin, Pamela M|Thangaraju, Muthusamy|Ganapathy, Vadivel|Waller, Jennifer L|Shi, Huidong|Robertson, Keith D|Munn, David H|Liu, Kebin
PMID: 22517765
Journal: Cell Cycle. 2012 Jun 1;11(11):2206-15.
Title: The tumor suppressor HINT1 regulates MITF and beta-catenin transcriptional activity in melanoma cells.
Author: Genovese, Giannicola|Ghosh, Papia|Li, Haiyang|Rettino, Alessando|Sioletic, Stefano|Cittadini, Achille|Sgambato, Alessandro
PMID: 22647378
Journal: FEBS Lett. 2012 Sep 21;586(19):3013-7.
Title: STAT3 repressed USP7 expression is crucial for colon cancer development.
Author: Yang, Zhi|Huo, Shoujun|Shan, Yuanzhou|Liu, Haijun|Xu, Yume|Yao, Kai|Li, Xianwei|Zhang, Xueli
PMID: 22750444
Journal: Anticancer Res. 2012 Jul;32(7):2855-62.
Title: Anti-invasive effects and proapoptotic activity induction by the rexinoid IIF and valproic acid in combination on colon cancer cell lines.
Author: Papi, A|Ferreri, A M|Guerra, F|Orlandi, M
PMID: 22753748
Journal: Biochim Biophys Acta. 2012 Oct;1821(10):1334-40.
Title: Mechanism and stereoselectivity of HDAC I inhibition by (R)-9-hydroxystearic acid in colon cancer.
Author: Parolin, Carola|Calonghi, Natalia|Presta, Enrica|Boga, Carla|Caruana, Paolo|Naldi, Marina|Andrisano, Vincenza|Masotti, Lanfranco|Sartor, Giorgio
PMID: 22814230
Journal: Oncol Rep. 2012 Dec;28(6):1997-2002.
Title: UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.
Author: Kofunato, Yasuhide|Kumamoto, Kensuke|Saitou, Katsuharu|Hayase, Suguru|Okayama, Hirokazu|Miyamoto, Kotaro|Sato, Yu|Katakura, Kyoko|Nakamura, Izumi|Ohki, Shinji|Koyama, Yoshihisa|Unoki, Motoko|Takenoshita, Seiichi
PMID: 23023523
Journal: Biochem Biophys Res Commun. 2013 Jan 4;430(1):381-6.
Title: Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells.
Author: Jeong, Jin Boo|Lee, Seong-Ho
PMID: 23159608
Journal: J Nutr Metab. 2013;2013:821082.
Title: Plant polyphenols and oxidative metabolites of the herbal alkenylbenzene methyleugenol suppress histone deacetylase activity in human colon carcinoma cells.
Author: Groh, Isabel Anna Maria|Chen, Chen|Luske, Claudia|Cartus, Alexander Thomas|Esselen, Melanie
PMID: 23476753
Journal: Gene. 2013 Jul 25;524(2):214-9.
Title: Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells.
Author: Zhang, Rui|Kang, Kyoung Ah|Kim, Ki Cheon|Na, Soo-Young|Chang, Weon Young|Kim, Gi Young|Kim, Hye Sun|Hyun, Jin Won
PMID: 23618814
Journal: PLoS One. 2013 May 28;8(5):e64600.
Title: HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure.
Author: Stypula-Cyrus, Yolanda|Damania, Dhwanil|Kunte, Dhananjay P|Cruz, Mart Dela|Subramanian, Hariharan|Roy, Hemant K|Backman, Vadim
PMID: 23724067
Journal: Carcinogenesis. 2013 Dec;34(12):2842-50.
Title: Dietary black raspberries modulate DNA methylation in dextran sodium sulfate (DSS)-induced ulcerative colitis.
Author: Wang, Li-Shu|Kuo, Chieh-Ti|Stoner, Kristen|Yearsley, Martha|Oshima, Kiyoko|Yu, Jianhua|Huang, Tim H-M|Rosenberg, Daniel|Peiffer, Dan|Stoner, Gary|Huang, Yi-Wen
PMID: 24067901
Journal: Cancer Prev Res (Phila). 2013 Dec;6(12):1317-27.
Title: Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue.
Author: Wang, Li-Shu|Kuo, Chieh-Ti|Huang, Tim H-M|Yearsley, Martha|Oshima, Kiyoko|Stoner, Gary D|Yu, Jianhua|Lechner, John F|Huang, Yi-Wen
PMID: 24129635
Journal: Oncogene. 2014 Apr 24;33(17):2157-68.
Title: The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.
Author: Cai, Y|Geutjes, E-J|de Lint, K|Roepman, P|Bruurs, L|Yu, L-R|Wang, W|van Blijswijk, J|Mohammad, H|de Rink, I|Bernards, R|Baylin, S B
PMID: 23708667
Journal: Exp Cell Res. 2014 May 15;324(1):40-53.
Title: Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Author: Saldanha, Sabita N|Kala, Rishabh|Tollefsbol, Trygve O
PMID: 24518414
Journal: J Med Chem. 2014 May 22;57(10):4009-22.
Title: Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells.
Author: Lee, Hsueh-Yun|Tsai, An-Chi|Chen, Mei-Chuan|Shen, Po-Jung|Cheng, Yun-Ching|Kuo, Ching-Chuan|Pan, Shiow-Lin|Liu, Yi-Min|Liu, Jin-Fen|Yeh, Teng-Kuang|Wang, Jing-Chi|Chang, Chi-Yen|Chang, Jang-Yang|Liou, Jing-Ping
PMID: 24766560
Journal: Cancer Biol Ther. 2014 Sep;15(9):1198-207.
Title: The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer.
Author: Wang, Jian|Elahi, Abul|Ajidahun, Abidemi|Clark, Whalen|Hernandez, Jonathan|Achille, Alex|Hao, Ji-hui|Seto, Edward|Shibata, David
PMID: 24919179
Journal: FASEB J. 2014 Oct;28(10):4265-79.
Title: Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators.
Author: Yang, Hui|Salz, Tal|Zajac-Kaye, Maria|Liao, Daiqing|Huang, Suming|Qiu, Yi
PMID: 24948597
Journal: Oncotarget. 2014 Jul 30;5(14):5651-62.
Title: A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCdelta and E-cadherin.
Author: Wang, Li-Ting|Liou, Jing-Ping|Li, Yu-Hsuan|Liu, Yi-Min|Pan, Shiow-Lin|Teng, Che-Ming
PMID: 25015091
Journal: Eur J Med Chem. 2014 Oct 30;86:528-41.
Title: Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups.
Author: Bhansali, Pravin|Hanigan, Christin L|Perera, Lalith|Casero, Robert A Jr|Tillekeratne, L M Viranga
PMID: 25203782
Journal: Cell Death Dis. 2014 Oct 16;5:e1476.
Title: HDAC8 and STAT3 repress BMF gene activity in colon cancer cells.
Author: Kang, Y|Nian, H|Rajendran, P|Kim, E|Dashwood, W M|Pinto, J T|Boardman, L A|Thibodeau, S N|Limburg, P J|Lohr, C V|Bisson, W H|Williams, D E|Ho, E|Dashwood, R H
PMID: 25321483
Journal: PLoS One. 2014 Nov 25;9(11):e113071.
Title: Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma.
Author: Drew, Janice E|Farquharson, Andrew J|Mayer, Claus Dieter|Vase, Hollie F|Coates, Philip J|Steele, Robert J|Carey, Francis A
PMID: 25423035
Journal: Histopathology. 2015 Jan;66(2):270-82.
Title: Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer.
Author: Benard, Anne|Goossens-Beumer, Ines J|van Hoesel, Anneke Q|Horati, Hamed|de Graaf, Wouter|Putter, Hein|Zeestraten, Eliane C M|Liefers, Gerrit-Jan|van de Velde, Cornelis J H|Kuppen, Peter J K
PMID: 25307864
Journal: Biochem Biophys Res Commun. 2015 Jan 2;456(1):320-6.
Title: Trichostatin A, a histone deacetylase inhibitor, reverses epithelial-mesenchymal transition in colorectal cancer SW480 and prostate cancer PC3 cells.
Author: Wang, Xiaoxiong|Xu, Jun|Wang, Hao|Wu, Long|Yuan, Weiqi|Du, Jun|Cai, Shaohui
PMID: 25434997
Journal: Oncol Rep. 2015 Oct;34(4):1905-14.
Title: Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer.
Author: Gerceker, Emre|Boyacioglu, Seda Orenay|Kasap, Elmas|Baykan, Ahmed|Yuceyar, Hakan|Yildirim, Hatice|Ayhan, Semin|Ellidokuz, Ender|Korkmaz, Mehmet
PMID: 26259750
Journal: Org Biomol Chem. 2015 Oct 28;13(40):10226-35.
Title: Pyrimidinedione-mediated selective histone deacetylase 6 inhibitors with antitumor activity in colorectal cancer HCT116 cells.
Author: Liu, Yi-Min|Lee, Hsueh-Yun|Lai, Mei-Jung|Pan, Shiow-Lin|Huang, Hsiang-Ling|Kuo, Fei-Chiao|Chen, Mei-Chuan|Liou, Jing-Ping
PMID: 26309122
Journal: Oncotarget. 2015 Sep 29;6(29):27427-39.
Title: The positive feedback between Snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer.
Author: Wang, Jianmei|Zhu, Xiaohui|Hu, Jinlong|He, Guoyang|Li, Xiaomei|Wu, Pingxiang|Ren, Xiaoli|Wang, Feifei|Liao, Wenting|Liang, Li|Ding, Yanqing
PMID: 26336990
Journal: Oncol Rep. 2015 Nov;34(5):2238-50.
Title: HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population.
Author: Ler, Ser Yeng|Leung, Carol Ho Wing|Khin, Lay Wai|Lu, Guo-Dong|Salto-Tellez, Manuel|Hartman, Mikael|Iau, Philip Tsau Choong|Yap, Celestial T|Hooi, Shing Chuan
PMID: 26352599
Journal: Int J Oncol. 2015 Dec;47(6):2264-75.
Title: Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.
Author: Cacan, Ercan|Greer, Susanna F|Garnett-Benson, Charlie
PMID: 26458736
Journal: Tumour Biol. 2016 Mar;37(3):3071-80.
Title: The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma.
Author: Kasap, Elmas|Gerceker, Emre|Boyacioglu, Seda Orenay|Yuceyar, Hakan|Yildirm, Hatice|Ayhan, Semin|Korkmaz, Mehmet
PMID: 26423403
Journal: Gastroenterology. 2016 Mar;150(3):659-671.e16.
Title: OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.
Author: Ye, Guo-Dong|Sun, Guang-Bin|Jiao, Peng|Chen, Chen|Liu, Qing-Feng|Huang, Xiao-Li|Zhang, Rui|Cai, Wang-Yu|Li, Sheng-Nan|Wu, Jia-Fa|Liu, Yun-Jia|Wu, Rong-Si|Xie, Yuan-Yuan|Chan, Err-Cheng|Liou, Yih-Cherng|Li, Bo-An
PMID: 26619963
Journal: Neoplasma. 2016;63(2):193-200.
Title: Chidamide and 5-flurouracil show a synergistic antitumor effect on human colon cancer xenografts in nude mice.
Author: Liu, L|Qiu, S|Liu, Y|Liu, Z|Zheng, Y|Su, X|Chen, B|Chen, H
PMID: 26774139
Journal: Tumour Biol. 2016 Aug;37(8):10257-67.
Title: Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells.
Author: Zhijun, Huang|Shusheng, Wang|Han, Min|Jianping, Li|Li-Sen, Qin|Dechun, Li
PMID: 26831668
Journal: Mol Cancer Res. 2016 Apr;14(4):385-96.
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
Author: Ghaleb, Amr M|Elkarim, Enas A|Bialkowska, Agnieszka B|Yang, Vincent W
PMID: 26839262
Journal: Cancer Chemother Pharmacol. 2016 Mar;77(3):613-21.
Title: Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription.
Author: Ye, Pingjiang|Xing, Haibo|Lou, Fang|Wang, Kaifeng|Pan, Qin|Zhou, Xiaoyun|Gong, Liu|Li, Da
PMID: 26846508
Journal: Oncotarget. 2016 May 3;7(18):25862-71.
Title: HDAC1 controls CIP2A transcription in human colorectal cancer cells.
Author: Balliu, Manjola|Cellai, Cristina|Lulli, Matteo|Laurenzana, Anna|Torre, Eugenio|Vannucchi, Alessandro Maria|Paoletti, Francesco
PMID: 27029072
Journal: Elife. 2016 Apr 14;5.
Title: A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.
Author: Wang, Lihua|Bu, Pengcheng|Ai, Yiwei|Srinivasan, Tara|Chen, Huanhuan Joyce|Xiang, Kun|Lipkin, Steven M|Shen, Xiling
PMID: 27077950
Journal: Am J Cancer Res. 2016 Feb 15;6(3):664-76. eCollection 2016.
Title: Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro.
Author: Lutz, Lisa|Fitzner, Ingrid Coutino|Ahrens, Theresa|Geissler, Anna-Lena|Makowiec, Frank|Hopt, Ulrich T|Bogatyreva, Lioudmila|Hauschke, Dieter|Werner, Martin|Lassmann, Silke
PMID: 27152243
Journal: Arch Toxicol. 2017 May;91(5):2135-2150.
Title: Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models.
Author: Zapletal, Ondrej|Tylichova, Zuzana|Neca, Jiri|Kohoutek, Jiri|Machala, Miroslav|Milcova, Alena|Pokorna, Michaela|Topinka, Jan|Moyer, Mary Pat|Hofmanova, Jirina|Kozubik, Alois|Vondracek, Jan
PMID: 27830268
Journal: J Cell Physiol. 2017 Jul;232(7):1914-1921.
Title: Cytoplasmic Localization of RUNX3 via Histone Deacetylase-Mediated SRC Expression in Oxidative-Stressed Colon Cancer Cells.
Author: Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Maeng, Young Hee|Hyun, Jin Won
PMID: 27990641
Journal: Eur J Med Chem. 2017 Jul 7;134:185-206.
Title: Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.
Author: Li, Xiaoyang|Zhang, Yingjie|Jiang, Yuqi|Wu, Jingde|Inks, Elizabeth S|Chou, C James|Gao, Shuai|Hou, Jinning|Ding, Qinge|Li, Jingyao|Wang, Xue|Huang, Yongxue|Xu, Wenfang
PMID: 28415009
Journal: Oncotarget. 2017 Jun 13;8(24):39241-39253.
Title: The expression of histone deacetylase HDAC1 correlates with the progression and prognosis of gastrointestinal malignancy.
Author: Cao, Lin-Lin|Yue, Zhihong|Liu, Lianhua|Pei, Lin|Yin, Yue|Qin, Li|Zhao, Jie|Liu, Huixin|Wang, Hui|Jia, Mei
PMID: 28424407
Journal: Biochem Biophys Res Commun. 2017 Jun 3;487(3):716-722.
Title: TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells.
Author: Eshelman, Melanie A|Shah, Meera|Raup-Konsavage, Wesley M|Rennoll, Sherri A|Yochum, Gregory S
PMID: 28450117
Journal: Mol Med Rep. 2017 Nov;16(5):7367-7374.
Title: ING2, a tumor associated gene, enhances PAI1 and HSPA1A expression with HDAC1 and mSin3A through the PHD domain and Cterminal.
Author: Ohkouchi, Chiyo|Kumamoto, Kensuke|Saito, Motonobu|Ishigame, Teruhide|Suzuki, Shin-Ichi|Takenoshita, Seiichi|Harris, Cutis C
PMID: 28944862
Journal: Anticancer Res. 2018 Jan;38(1):271-277.
Title: Up-regulation of UVRAG by HDAC1 Inhibition Attenuates 5FU-induced Cell Death in HCT116 Colorectal Cancer Cells.
Author: Jo, Yoon Kyung|Park, Na Yeon|Shin, Ji Hyun|Jo, Doo Sin|Bae, Ji-Eun|Choi, Eun Sun|Maeng, Sungho|Jeon, Hong Bae|Roh, Seon Ae|Chang, Jong Wook|Kim, Jin Cheon|Cho, Dong-Hyung
PMID: 29277783
Journal: Int J Immunopathol Pharmacol. 2018 Jan-Dec;32:394632017752240.
Title: Sodium butyrate has anti-proliferative, pro-differentiating, and immunomodulatory effects in osteosarcoma cells and counteracts the TNFalpha-induced low-grade inflammation.
Author: Perego, Silvia|Sansoni, Veronica|Banfi, Giuseppe|Lombardi, Giovanni
PMID: 29363375
Journal: Adv Clin Exp Med. 2018 Mar;27(3):305-311.
Title: Deregulated expression of HDAC3 in colorectal cancer and its clinical significance.
Author: Nemati, Masoumeh|Ajami, Naser|Estiar, Mehrdad Asghari|Rezapour, Saleheh|Gavgani, Reyhaneh Ravanbakhsh|Hashemzadeh, Shahryar|Kafil, Hossein Samadi|Sakhinia, Ebrahim
PMID: 29558042
Journal: Blood. 2018 Jun 21;131(25):2789-2802.
Title: TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.
Author: Jethwa, Alexander|Slabicki, Mikolaj|Hullein, Jennifer|Jentzsch, Marius|Dalal, Vineet|Rabe, Sophie|Wagner, Lena|Walther, Tatjana|Klapper, Wolfram|Bohnenberger, Hanibal|Rettel, Mandy|Lu, Junyan|Smits, Arne H|Stein, Frank|Savitski, Mikhail M|Huber, Wolfgang|
PMID: 29653964
Journal: JCI Insight. 2018 Apr 19;3(8). pii: 91316.
Title: Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
Author: Kanda, Keitaro|Sakamoto, Jiro|Matsumoto, Yoshihide|Ikuta, Kozo|Goto, Norihiro|Morita, Yusuke|Ohno, Mikiko|Nishi, Kiyoto|Eto, Koji|Kimura, Yuto|Nakanishi, Yuki|Ikegami, Kanako|Yoshikawa, Takaaki|Fukuda, Akihisa|Kawada, Kenji|Sakai, Yoshiharu|Ito, Akihiro|Y
PMID: 29669932
Journal: Cancer Lett. 2018 Sep 1;431:43-53.
Title: Nemo-like kinase (NLK) primes colorectal cancer progression by releasing the E2F1 complex from HDAC1.
Author: Li, Shang-Ze|Zeng, Feng|Li, Jun|Shu, Qi-Peng|Zhang, Hui-Hui|Xu, Jun|Ren, Jian-Wei|Zhang, Xiao-Dong|Song, Xue-Min|Du, Run-Lei
PMID: 29803790
Journal: Oncol Lett. 2018 Aug;16(2):1863-1868.
Title: Aneuploidy of chromosome 8 and mutation of circulating tumor cells predict pathologic complete response in the treatment of locally advanced rectal cancer.
Author: Wan, Jue-Feng|Li, Xue-Qin|Zhang, Jing|Yang, Li-Feng|Zhu, Ji|Li, Gui-Chao|Liang, Li-Ping|Shen, Li-Jun|Zhang, Hui|Li, Jing|Zhang, Yi-Tong|Chen, Chang-Yue|Zhang, Zhen
PMID: 30008877
Journal: FASEB J. 2018 Sep 25:fj201801390R.
Title: RARbeta acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.
Author: Hu, Ying|French, Samuel W|Chau, Thinh|Liu, Hui-Xin|Sheng, Lili|Wei, Fang|Stondell, Jesse|Garcia, Juan C|Du, Yanlei|Bowlus, Christopher L|Wan, Yu-Jui Yvonne
PMID: 30252536