Primary Site >> Colorectal Cancer

Gene >> HCRTR1

Journal: FASEB J. 2008 Jun;22(6):1993-2002.
Title: A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism.
Author: Voisin, Thierry|El Firar, Aadil|Rouyer-Fessard, Christiane|Gratio, Valerie|Laburthe, Marc
PMID: 18198212
Journal: Cancer Res. 2011 May 1;71(9):3341-51.
Title: Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis.
Author: Voisin, Thierry|El Firar, Aadil|Fasseu, Magali|Rouyer-Fessard, Christiane|Descatoire, Veronique|Walker, Francine|Paradis, Valerie|Bedossa, Pierre|Henin, Dominique|Lehy, Therese|Laburthe, Marc
PMID: 21415167
Journal: Br J Pharmacol. 2012 Mar;165(6):1678-87.
Title: The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.
Author: Laburthe, Marc|Voisin, Thierry
PMID: 21627633
Journal: Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1153-1164.
Title: Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein-dependent signaling and migration in the human colon cancer cell line HT-29.
Author: Bai, Bo|Chen, Xiaoyu|Zhang, Rumin|Wang, Xin|Jiang, Yunlu|Li, Dandan|Wang, Zhengwen|Chen, Jing
PMID: 28288880
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3618-3628.
Title: Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A.
Author: Messal, N|Fernandez, N|Dayot, S|Gratio, V|Nicole, P|Prochasson, C|Chantret, I|LeGuilloux, G|Jarry, A|Couvelard, A|Treton, X|Voisin, T|Ogier-Denis, E|Couvineau, A
PMID: 30251681