Primary Site >> Colorectal Cancer
Gene >> HCRTR1
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Ref: A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism. PMID: 18198212 |
Ref: Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis. PMID: 21415167 |
Ref: The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs. PMID: 21627633 |
Ref: Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein-dependent signaling and migration in the human colon cancer cell line HT-29. PMID: 28288880 |
Ref: Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A. PMID: 30251681 |