Primary Site >> Stomach Cancer

Gene >> HBEGF

Journal: Int J Cancer. 1996 May 3;66(3):315-21.
Title: Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma.
Author: Naef, M|Yokoyama, M|Friess, H|Buchler, M W|Korc, M
PMID: 8621250
Journal: Int J Cancer. 2002 Apr 1;98(4):505-13.
Title: Significance of the association between heparin-binding epidermal growth factor-like growth factor and CD9 in human gastric cancer.
Author: Murayama, Yoko|Miyagawa, Jun-ichiro|Shinomura, Yasuhisa|Kanayama, Shuji|Isozaki, Koji|Yamamori, Katsumi|Mizuno, Hitoshi|Ishiguro, Shingo|Kiyohara, Tatsuya|Miyazaki, Yoshiji|Taniguchi, Naoyuki|Higashiyama, Shigeki|Matsuzawa, Yuji
PMID: 11920609
Journal: Recent Results Cancer Res. 2003;162:115-32.
Title: Clinical implications of the EGF receptor/ligand system for tumor progression and survival in gastrointestinal carcinomas: evidence for new therapeutic options.
Author: Kopp, Reinhard|Rothbauer, Elisabeth|Ruge, Maximilian|Arnholdt, Hans|Spranger, Joachim|Muders, M|Pfeiffer, Doris G|Schildberg, Friedrich Wilhelm|Pfeiffer, Andreas
PMID: 12790326
Journal: Cancer Sci. 2003 Apr;94(4):355-9.
Title: Possible chemoresistance-related genes for gastric cancer detected by cDNA microarray.
Author: Suganuma, Kazuhiro|Kubota, Tetsuro|Saikawa, Yoshiro|Abe, Sadanori|Otani, Yoshihide|Furukawa, Toshiharu|Kumai, Koichiro|Hasegawa, Hirotoshi|Watanabe, Masahiko|Kitajima, Masaki|Nakayama, Hironobu|Okabe, Hisafumi
PMID: 12824904
Journal: Am J Physiol Gastrointest Liver Physiol. 2004 Jun;286(6):G992-9. Epub 2004 Feb 5.
Title: Gastrin regulates the heparin-binding epidermal-like growth factor promoter via a PKC/EGFR-dependent mechanism.
Author: Sinclair, Natalie F|Ai, Wandong|Raychowdhury, Raktima|Bi, Meixia|Wang, Timothy C|Koh, Theodore J|McLaughlin, John T
PMID: 14764442
Journal: Gastroenterology. 2004 Aug;127(2):559-69.
Title: The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells.
Author: Tanida, Satoshi|Joh, Takashi|Itoh, Keisuke|Kataoka, Hiromi|Sasaki, Makoto|Ohara, Hirotaka|Nakazawa, Takahiro|Nomura, Tomoyuki|Kinugasa, Yumi|Ohmoto, Hiroshi|Ishiguro, Hiroshi|Yoshino, Kohichiro|Higashiyama, Shigeki|Itoh, Makoto
PMID: 15300588
Journal: Int J Mol Med. 2006 Jun;17(6):1163-6.
Title: Canonical WNT signaling pathway and human AREG.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16685431
Journal: Biochem Biophys Res Commun. 2007 Mar 2;354(1):154-9. Epub 2006 Dec 29.
Title: Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells.
Author: Yasuda, Hiroshi|Hirata, Shuko|Inoue, Kazuaki|Mashima, Hirosato|Ohnishi, Hirohide|Yoshiba, Makoto
PMID: 17214962
Journal: Clin Cancer Res. 2008 Jun 15;14(12):3956-65.
Title: Suppression of proHB-EGF carboxy-terminal fragment nuclear translocation: a new molecular target therapy for gastric cancer.
Author: Shimura, Takaya|Kataoka, Hiromi|Ogasawara, Naotaka|Kubota, Eiji|Sasaki, Makoto|Tanida, Satoshi|Joh, Takashi
PMID: 18559618
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jan;29(1):44-6.
Title: [Expression of heparin-binding epidermal growth factor-like growth factor in patients with gastric carcinoma].
Author: Wang, Guo-rong|Zheng, Yan|Che, Xiang-ming|Wang, Xiao-qiang|Wang, Xaio-wei|Pan, Cheng-en|He, Wen-xian
PMID: 19218109
Journal: Br J Cancer. 2009 Apr 21;100(8):1320-9.
Title: BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers.
Author: Hirata, Y|Ogasawara, N|Sasaki, M|Mizushima, T|Shimura, T|Mizoshita, T|Mori, Y|Kubota, E|Wada, T|Tanida, S|Kataoka, H|Kamiya, T|Higashiyama, S|Joh, T
PMID: 19337254
Journal: Anticancer Res. 2010 Aug;30(8):3143-9.
Title: HB-EGF inhibition in combination with various anticancer agents enhances its antitumor effects in gastric cancer.
Author: Sanui, Ayako|Yotsumoto, Fusanori|Tsujioka, Hiroshi|Fukami, Tatsuya|Horiuchi, Shinji|Shirota, Kyoko|Yoshizato, Toshiyuki|Kawarabayashi, Tatsuhiko|Kuroki, Masahide|Miyamoto, Shingo
PMID: 20871033
Journal: Biochem Biophys Res Commun. 2010 Nov 19;402(3):449-54.
Title: TGFbeta induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells.
Author: Ebi, Masahide|Kataoka, Hiromi|Shimura, Takaya|Kubota, Eiji|Hirata, Yoshikazu|Mizushima, Takashi|Mizoshita, Tsutomu|Tanaka, Mamoru|Mabuchi, Motoshi|Tsukamoto, Hironobu|Tanida, Satoshi|Kamiya, Takeshi|Higashiyama, Shigeki|Joh, Takashi
PMID: 20934403
Journal: Cancer Res. 2010 Jul 15;70(14):6093-103.
Title: Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor.
Author: Koshikawa, Naohiko|Mizushima, Hiroto|Minegishi, Tomoko|Iwamoto, Ryo|Mekada, Eisuke|Seiki, Motoharu
PMID: 20587521
Journal: Cancer Sci. 2011 Jan;102(1):111-6.
Title: Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells.
Author: Koshikawa, Naohiko|Mizushima, Hiroto|Minegishi, Tomoko|Eguchi, Fuyuki|Yotsumoto, Fusanori|Nabeshima, Kazuki|Miyamoto, Shingo|Mekada, Eisuke|Seiki, Motoharu
PMID: 20946474
Journal: Cancer Sci. 2011 Apr;102(4):713-9.
Title: Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis.
Author: Oshima, Hiroko|Popivanova, Boryana K|Oguma, Keisuke|Kong, Dan|Ishikawa, Tomo-o|Oshima, Masanobu
PMID: 21205091
Journal: Clin Cancer Res. 2011 Jun 1;17(11):3619-30.
Title: The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.
Author: Yasumoto, Kazuo|Yamada, Tadaaki|Kawashima, Atsuhiro|Wang, Wei|Li, Qi|Donev, Ivan Shterev|Tacheuchi, Shinji|Mouri, Hisatsugu|Yamashita, Kaname|Ohtsubo, Koushiro|Yano, Seiji
PMID: 21482691
Journal: Oncol Lett. 2014 Feb;7(2):444-448.
Title: Treatment of capecitabine-induced hand-foot syndrome using a topical retinoid: A case report.
Author: Inokuchi, Masafumi|Ishikawa, Satoko|Furukawa, Hiroyuki|Takamura, Hiroyuki|Ninomiya, Itasu|Kitagawa, Hirohisa|Fushida, Sachio|Fujimura, Takashi|Ohta, Tetsuo
PMID: 24396465
Journal: World J Gastroenterol. 2015 Feb 21;21(7):2080-8.
Title: Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancer.
Author: Chung, Hye Won|Kong, Hoon Young|Lim, Jong-Baeck
PMID: 25717241
Journal: Oncol Rep. 2015 Dec;34(6):3140-6.
Title: Silencing beta-linked N-acetylglucosamine transferase induces apoptosis in human gastric cancer cells through PUMA and caspase-3 pathways.
Author: Wen, Ti|Hou, Kezuo|Li, Zhi|Li, Lu|Yu, Hanjie|Liu, Yunpeng|Li, Yangguang|Yin, Zhinan
PMID: 26397041
Journal: J Cancer Res Clin Oncol. 2017 Apr;143(4):573-600.
Title: Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.
Author: Kneissl, Julia|Hartmann, Anja|Pfarr, Nicole|Erlmeier, Franziska|Lorber, Thomas|Keller, Simone|Zwingenberger, Gwen|Weichert, Wilko|Luber, Birgit
PMID: 27933395
Journal: Pathobiology. 2017;84(4):210-217.
Title: Expression of the ERBB Family of Ligands and Receptors in Gastric Cancer.
Author: Byeon, Sun-Ju|Lee, Hye Seung|Kim, Min-A|Lee, Byung Lan|Kim, Woo Ho
PMID: 28399526
Journal: Front Cell Infect Microbiol. 2018 Jan 15;7:541.
Title: Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway.
Author: Gunawardhana, Niluka|Jang, Sungil|Choi, Yun Hui|Hong, Youngmin A|Jeon, Yeong-Eui|Kim, Aeryun|Su, Hanfu|Kim, Ji-Hye|Yoo, Yun-Jung|Merrell, D Scott|Kim, Jinmoon|Cha, Jeong-Heon
PMID: 29379775
Journal: J Gastrointest Oncol. 2018 Jun;9(3):553-559.
Title: Aggressive mutation in a familial adenomatous polyposis syndrome family: when phenotype guides clinical surveillance.
Author: Neffa, Florencia|Garcia, Lucia|Della Valle, Adriana|Carusso, Florencia|Vergara, Carolina|Sanchez, Daniel|Sapone, Marta|Silveyra, Noelia|Revello, Ana Laura|Esperon, Patricia
PMID: 29998021