Primary Site >> Colorectal Cancer
Gene >> GUCY2C
| 1. | |||||||||||
| Journal: | Carcinogenesis. 2008 Aug;29(8):1601-7. | ||||||||||
| Title: | Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells. | ||||||||||
| Author: | Pitari, Giovanni M|Lin, Jieru E|Shah, Fawad J|Lubbe, Wilhelm J|Zuzga, David S|Li, Peng|Schulz, Stephanie|Waldman, Scott A | ||||||||||
| PMID: | 18566015 | ||||||||||
| 2. | |||||||||||
| Journal: | JAMA. 2009 Feb 18;301(7):745-52. | ||||||||||
| Title: | Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer. | ||||||||||
| Author: | Waldman, Scott A|Hyslop, Terry|Schulz, Stephanie|Barkun, Alan|Nielsen, Karl|Haaf, Janis|Bonaccorso, Christine|Li, Yanyan|Weinberg, David S | ||||||||||
| PMID: | 19224751 | ||||||||||
| 3. | |||||||||||
| Journal: | Expert Rev Mol Diagn. 2009 Nov;9(8):777-85. | ||||||||||
| Title: | GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients. | ||||||||||
| Author: | Mejia, Alex|Schulz, Stephanie|Hyslop, Terry|Weinberg, David S|Waldman, Scott A | ||||||||||
| PMID: | 19895223 | ||||||||||
| 4. | |||||||||||
| Journal: | Gastroenterology. 2010 Jan;138(1):241-54. | ||||||||||
| Title: | The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. | ||||||||||
| Author: | Lin, Jieru Egeria|Li, Peng|Snook, Adam Eugene|Schulz, Stephanie|Dasgupta, Abhijit|Hyslop, Terry Marie|Gibbons, Ahmara Vivian|Marszlowicz, Glen|Pitari, Giovanni Mario|Waldman, Scott Arthur | ||||||||||
| PMID: | 19737566 | ||||||||||
| 5. | |||||||||||
| Journal: | Adv Clin Chem. 2010;52:19-39. | ||||||||||
| Title: | Molecular staging estimates occult tumor burden in colorectal cancer. | ||||||||||
| Author: | Mejia, Alex|Schulz, Stephanie|Hyslop, Terry|Weinberg, David S|Waldman, Scott A | ||||||||||
| PMID: | 21275338 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 2011 May 15;17(10):3293-303. | ||||||||||
| Title: | Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer. | ||||||||||
| Author: | Hyslop, Terry|Weinberg, David S|Schulz, Stephanie|Barkun, Alan|Waldman, Scott A | ||||||||||
| PMID: | 21307149 | ||||||||||
| 7. | |||||||||||
| Journal: | Immunol Res. 2011 Dec;51(2-3):161-9. | ||||||||||
| Title: | GUCY2C-targeted cancer immunotherapy: past, present and future. | ||||||||||
| Author: | Snook, Adam E|Magee, Michael S|Waldman, Scott A | ||||||||||
| PMID: | 22038530 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer. 2012 May 1;118(9):2532-40. | ||||||||||
| Title: | Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes. | ||||||||||
| Author: | Hyslop, Terry|Weinberg, David S|Schulz, Stephanie|Barkun, Alan|Waldman, Scott A | ||||||||||
| PMID: | 21887684 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2012 May;61(5):713-23. | ||||||||||
| Title: | Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C. | ||||||||||
| Author: | Snook, Adam E|Magee, Michael S|Marszalowicz, Glen P|Schulz, Stephanie|Waldman, Scott A | ||||||||||
| PMID: | 22057677 | ||||||||||
| 10. | |||||||||||
| Journal: | J Surg Oncol. 2012 Jul 1;106(1):24-30. | ||||||||||
| Title: | Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer. | ||||||||||
| Author: | Hyslop, Terry|Weinberg, David S|Schulz, Stephanie|Barkun, Alan|Waldman, Scott A | ||||||||||
| PMID: | 22252429 | ||||||||||
| 11. | |||||||||||
| Journal: | Biomark Med. 2012 Jun;6(3):339-48. | ||||||||||
| Title: | GUCY2C molecular staging personalizes colorectal cancer patient management. | ||||||||||
| Author: | Gong, Jian P|Schulz, Stephanie|Hyslop, Terry|Waldman, Scott A | ||||||||||
| PMID: | 22731908 | ||||||||||
| 12. | |||||||||||
| Journal: | Trends Endocrinol Metab. 2013 Apr;24(4):165-73. | ||||||||||
| Title: | GUCY2C: at the intersection of obesity and cancer. | ||||||||||
| Author: | Kim, Gilbert W|Lin, Jieru E|Waldman, Scott A | ||||||||||
| PMID: | 23375388 | ||||||||||
| 13. | |||||||||||
| Journal: | J Cancer. 2013;4(3):193-9. | ||||||||||
| Title: | Molecular staging of node negative patients with colorectal cancer. | ||||||||||
| Author: | Hyslop, Terry|Waldman, Scott A | ||||||||||
| PMID: | 23459453 | ||||||||||
| 14. | |||||||||||
| Journal: | Expert Rev Clin Pharmacol. 2013 Sep;6(5):557-64. | ||||||||||
| Title: | Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis. | ||||||||||
| Author: | Blomain, Erik S|Lin, Jieru E|Kraft, Crystal L|Trela, Urszula T|Rock, Justin M|Aing, Amanda S|Snook, Adam E|Waldman, Scott A | ||||||||||
| PMID: | 23971873 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Res. 2013 Nov 15;73(22):6654-66. | ||||||||||
| Title: | Intestinal GUCY2C prevents TGF-beta secretion coordinating desmoplasia and hyperproliferation in colorectal cancer. | ||||||||||
| Author: | Gibbons, Ahmara V|Lin, Jieru E|Kim, Gilbert W|Marszalowicz, Glen P|Li, Peng|Stoecker, Brian A|Blomain, Erik S|Rattan, Satish|Snook, Adam E|Schulz, Stephanie|Waldman, Scott A | ||||||||||
| PMID: | 24085786 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2014 Nov;23(11):2328-37. | ||||||||||
| Title: | The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer. | ||||||||||
| Author: | Wilson, Chantell|Lin, Jieru E|Li, Peng|Snook, Adam E|Gong, Jianping|Sato, Takahiro|Liu, Chengbao|Girondo, Melanie A|Rui, Hallgeir|Hyslop, Terry|Waldman, Scott A | ||||||||||
| PMID: | 25304930 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2014 Oct 15;5(19):9460-71. | ||||||||||
| Title: | GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. | ||||||||||
| Author: | Marszalowicz, Glen P|Snook, Adam E|Magee, Michael S|Merlino, Dante|Berman-Booty, Lisa D|Waldman, Scott A | ||||||||||
| PMID: | 25294806 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1188-95. | ||||||||||
| Title: | Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C. | ||||||||||
| Author: | Witek, Matthew|Blomain, Erik S|Magee, Michael S|Xiang, Bo|Waldman, Scott A|Snook, Adam E | ||||||||||
| PMID: | 24661671 | ||||||||||
| 19. | |||||||||||
| Journal: | J Biol Chem. 2014 Jan 3;289(1):581-93. | ||||||||||
| Title: | Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21. | ||||||||||
| Author: | Basu, Nirmalya|Saha, Sayanti|Khan, Imran|Ramachandra, Subbaraya G|Visweswariah, Sandhya S | ||||||||||
| PMID: | 24217248 | ||||||||||
| 20. | |||||||||||
| Journal: | Eur J Immunol. 2014 Jul;44(7):1956-66. | ||||||||||
| Title: | Selective antigen-specific CD4(+) T-cell, but not CD8(+) T- or B-cell, tolerance corrupts cancer immunotherapy. | ||||||||||
| Author: | Snook, Adam E|Magee, Michael S|Schulz, Stephanie|Waldman, Scott A | ||||||||||
| PMID: | 24771148 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2016 Jan 15;76(2):339-46. | ||||||||||
| Title: | Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis. | ||||||||||
| Author: | Lin, Jieru E|Colon-Gonzalez, Francheska|Blomain, Erik|Kim, Gilbert W|Aing, Amanda|Stoecker, Brian|Rock, Justin|Snook, Adam E|Zhan, Tingting|Hyslop, Terry M|Tomczak, Michal|Blumberg, Richard S|Waldman, Scott A | ||||||||||
| PMID: | 26773096 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Biol Ther. 2016 Jul 2;17(7):713-8. | ||||||||||
| Title: | GUCY2C ligand replacement to prevent colorectal cancer. | ||||||||||
| Author: | Blomain, Erik S|Pattison, Amanda M|Waldman, Scott A | ||||||||||
| PMID: | 27104761 | ||||||||||
| 23. | |||||||||||
| Journal: | Mol Pharmacol. 2016 Sep;90(3):199-204. | ||||||||||
| Title: | Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer. | ||||||||||
| Author: | Blomain, Erik S|Merlino, Dante J|Pattison, Amanda M|Snook, Adam E|Waldman, Scott A | ||||||||||
| PMID: | 27251363 | ||||||||||
| 24. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Sep 28;22(36):8070-7. | ||||||||||
| Title: | Guanylyl cyclase C signaling axis and colon cancer prevention. | ||||||||||
| Author: | Pattison, Amanda M|Merlino, Dante J|Blomain, Erik S|Waldman, Scott A | ||||||||||
| PMID: | 27688649 | ||||||||||
| 25. | |||||||||||
| Journal: | BMC Cancer. 2016 Oct 3;16(1):766. | ||||||||||
| Title: | A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients. | ||||||||||
| Author: | Myers, Ronald E|Wolf, Thomas|Shwae, Phillip|Hegarty, Sarah|Peiper, Stephen C|Waldman, Scott A | ||||||||||
| PMID: | 27716119 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncoimmunology. 2016 Sep 2;5(10):e1227897. | ||||||||||
| Title: | GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity. | ||||||||||
| Author: | Magee, Michael S|Kraft, Crystal L|Abraham, Tara S|Baybutt, Trevor R|Marszalowicz, Glen P|Li, Peng|Waldman, Scott A|Snook, Adam E | ||||||||||
| PMID: | 27853651 | ||||||||||
| 27. | |||||||||||
| Journal: | Hum Gene Ther Methods. 2016 Dec;27(6):238-250. | ||||||||||
| Title: | Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope. | ||||||||||
| Author: | Snook, Adam E|Baybutt, Trevor R|Hyslop, Terry|Waldman, Scott A | ||||||||||
| PMID: | 27903079 | ||||||||||
| 28. | |||||||||||
| Journal: | Expert Rev Clin Pharmacol. 2017 May;10(5):549-557. | ||||||||||
| Title: | Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. | ||||||||||
| Author: | Aka, Allison A|Rappaport, Jeff A|Pattison, Amanda M|Sato, Takami|Snook, Adam E|Waldman, Scott A | ||||||||||
| PMID: | 28162021 | ||||||||||
| 29. | |||||||||||
| Journal: | Toxins (Basel). 2017 Sep 15;9(9). pii: toxins9090282. | ||||||||||
| Title: | The Heat-Stable Enterotoxin Receptor, Guanylyl Cyclase C, as a Pharmacological Target in Colorectal Cancer Immunotherapy: A Bench-to-Bedside Current Report. | ||||||||||
| Author: | Baybutt, Trevor R|Aka, Allison A|Snook, Adam E | ||||||||||
| PMID: | 28914772 | ||||||||||
| 30. | |||||||||||
| Journal: | Toxins (Basel). 2017 Sep 12;9(9). pii: toxins9090279. | ||||||||||
| Title: | ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. | ||||||||||
| Author: | Li, Peng|Lin, Jieru E|Snook, Adam E|Waldman, Scott A | ||||||||||
| PMID: | 28895923 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2017 Jun;10(6):345-354. | ||||||||||
| Title: | Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention. | ||||||||||
| Author: | Weinberg, David S|Lin, Jieru E|Foster, Nathan R|Della'Zanna, Gary|Umar, Asad|Seisler, Drew|Kraft, Walter K|Kastenberg, David M|Katz, Leo C|Limburg, Paul J|Waldman, Scott A | ||||||||||
| PMID: | 28396341 | ||||||||||
| 32. | |||||||||||
| Journal: | J Immunol. 2017 May 1;198(9):3507-3514. | ||||||||||
| Title: | Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8(+) T Cells. | ||||||||||
| Author: | Xiang, Bo|Baybutt, Trevor R|Berman-Booty, Lisa|Magee, Michael S|Waldman, Scott A|Alexeev, Vitali Y|Snook, Adam E | ||||||||||
| PMID: | 28341670 | ||||||||||
| 33. | |||||||||||
| Journal: | Stat Methods Med Res. 2018 Sep;27(9):2581-2595. | ||||||||||
| Title: | Modeling qRT-PCR dynamics with application to cancer biomarker quantification. | ||||||||||
| Author: | Chervoneva, Inna|Freydin, Boris|Hyslop, Terry|Waldman, Scott A | ||||||||||
| PMID: | 28504051 | ||||||||||
| 34. | |||||||||||
| Journal: | Cancer Immunol Res. 2018 May;6(5):509-516. | ||||||||||
| Title: | Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. | ||||||||||
| Author: | Magee, Michael S|Abraham, Tara S|Baybutt, Trevor R|Flickinger, John C Jr|Ridge, Natalie A|Marszalowicz, Glen P|Prajapati, Priyanka|Hersperger, Adam R|Waldman, Scott A|Snook, Adam E | ||||||||||
| PMID: | 29615399 | ||||||||||
| 35. | |||||||||||
| Journal: | Front Oncol. 2018 Aug 6;8:299. | ||||||||||
| Title: | The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. | ||||||||||
| Author: | Rappaport, Jeffrey A|Waldman, Scott A | ||||||||||
| PMID: | 30131940 | ||||||||||
| 36. | |||||||||||
| Journal: | Semin Cancer Biol. 2018 Sep 3. pii: S1044-579X(18)30064-6. | ||||||||||
| Title: | Targeting the paracrine hormone-dependent guanylate cyclase/cGMP/phosphodiesterases signaling pathway for colorectal cancer prevention. | ||||||||||
| Author: | Yarla, N S|Gali, H|Pathuri, G|Smriti, S|Farooqui, M|Panneerselvam, J|Kumar, G|Madka, V|Rao, C V | ||||||||||
| PMID: | 30189250 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncoimmunology. 2018 Jul 26;7(9):e1484978. | ||||||||||
| Title: | Non-thermal plasma induces immunogenic cell death in vivo in murine CT26 colorectal tumors. | ||||||||||
| Author: | Lin, Abraham G|Xiang, Bo|Merlino, Dante J|Baybutt, Trevor R|Sahu, Joya|Fridman, Alexander|Snook, Adam E|Miller, Vandana | ||||||||||
| PMID: | 30228954 | ||||||||||