Primary Site >> Colorectal Cancer

Gene >> GSTA1

Journal: Mutat Res. 2001 Oct 1;482(1-2):3-10.
Title: The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk.
Author: Coles, B|Nowell, S A|MacLeod, S L|Sweeney, C|Lang, N P|Kadlubar, F F
PMID: 11535243
Journal: Toxicology. 2002 Dec 27;181-182:83-7.
Title: Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.
Author: Sweeney, Carol|Coles, Brian F|Nowell, Susan|Lang, Nicholas P|Kadlubar, Fred F
PMID: 12505289
Journal: Carcinogenesis. 2003 Oct;24(10):1637-44. Epub 2003 Aug 1.
Title: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate.
Author: Ebert, Miriam Nannette|Klinder, Annett|Peters, Wilbert H M|Schaferhenrich, Anja|Sendt, Wolfgang|Scheele, Johannes|Pool-Zobel, Beatrice Louise
PMID: 12896903
Journal: Int J Cancer. 2003 Dec 20;107(6):878-84.
Title: Genetic polymorphisms and modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in human lymphocytes.
Author: Magagnotti, Cinzia|Pastorelli, Roberta|Pozzi, Simonetta|Andreoni, Bruno|Fanelli, Roberto|Airoldi, Luisa
PMID: 14601045
Journal: Carcinogenesis. 2004 Dec;25(12):2407-15. Epub 2004 Aug 19.
Title: Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.
Author: van der Logt, E M J|Bergevoet, S M|Roelofs, H M J|van Hooijdonk, Z|te Morsche, R H M|Wobbes, T|de Kok, J B|Nagengast, F M|Peters, W H M
PMID: 15319294
Journal: Oncol Rep. 2006 Sep;16(3):497-503.
Title: Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients.
Author: Romero, R Zarate|Morales, R|Garcia, F|Huarriz, M|Bandres, E|De la Haba, J|Gomez, A|Aranda, E|Garcia-Foncillas, J
PMID: 16865249
Journal: Pharmacogenomics. 2006 Jul;7(5):711-8.
Title: Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans.
Author: Martinez, Carmen|Martin, Felipe|Fernandez, Juana M|Garcia-Martin, Elena|Sastre, Javier|Diaz-Rubio, Manuel|Agundez, Jose Ag|Ladero, Jose M
PMID: 16886896
Journal: Br J Nutr. 2006 Oct;96(4):609-19.
Title: Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility.
Author: Reszka, Edyta|Wasowicz, Wojciech|Gromadzinska, Jolanta
PMID: 17010218
Journal: Neoplasma. 2006;53(6):463-70.
Title: Isothiocyanate iberin modulates phase II enzymes, posttranslational modification of histones and inhibits growth of Caco-2 cells by inducing apoptosis.
Author: Jakubikova, J|Bao, Y|Bodo, J|Sedlak, J
PMID: 17167713
Journal: Eur J Cancer. 2010 Jun;46(9):1617-31.
Title: GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis.
Author: Economopoulos, Konstantinos P|Sergentanis, Theodoros N
PMID: 20207535
Journal: Toxicol In Vitro. 2011 Apr;25(3):671-83.
Title: Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2.
Author: Niestroy, Jeanette|Barbara, Alfonso|Herbst, Kathrin|Rode, Sandra|van Liempt, Manuela|Roos, Peter H
PMID: 21256954
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jan;42(1):15-8, 36.
Title: [Analysis of gene expression patterns in an irinotecan-resistance colon cancer cell by cDNA microarray].
Author: Chen, Xi|Chen, Xiang-zheng|Liu, Ming|Lang, Nan|Tang, Qiu-lin|Chen, Ji|Zhao, Xiao-fei|Bi, Feng
PMID: 21355292
Journal: Drug Metab Pharmacokinet. 2011;26(6):646-58.
Title: Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.
Author: Maekawa, Keiko|Hamaguchi, Tetsuya|Saito, Yoshiro|Tatewaki, Naoko|Kurose, Kouichi|Kaniwa, Nahoko|Eguchi Nakajima, Takako|Kato, Ken|Yamada, Yasuhide|Shimada, Yasuhiro|Yoshida, Teruhiko|Kamatani, Naoyuki|Ura, Takashi|Saito, Miyuki|Muro, Kei|Fuse, Nozomu|Yosh
PMID: 21844655
Journal: Eur J Med Res. 2012 Jun 14;17:17.
Title: Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population.
Author: Hezova, Renata|Bienertova-Vasku, Julie|Sachlova, Milana|Brezkova, Veronika|Vasku, Anna|Svoboda, Marek|Radova, Lenka|Kiss, Igor|Vyzula, Rostislav|Slaby, Ondrej
PMID: 22697302
Journal: Int J Mol Epidemiol Genet. 2012;3(2):96-106. Epub 2012 May 15.
Title: Polymorphisms in heterocyclic aromatic amines metabolism-related genes are associated with colorectal adenoma risk.
Author: Eichholzer, Monika|Rohrmann, Sabine|Barbir, Aline|Hermann, Silke|Teucher, Birgit|Kaaks, Rudolf|Linseisen, Jakob
PMID: 22724046
Journal: Orphanet J Rare Dis. 2013 Nov 19;8:181.
Title: Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls.
Author: van Heumen, Bjorn W H|Roelofs, Hennie M J|te Morsche, Rene H M|Nagengast, Fokko M|Peters, Wilbert H M
PMID: 24245549
Journal: J BUON. 2015 Jan-Feb;20(1):287-95.
Title: Polymorphisms of GSTA1 contribute to elevated cancer risk: evidence from 15 studies.
Author: Deng, Qiwen|He, Bangshun|Pan, Yuqin|Sun, Huiling|Liu, Xian|Chen, Jie|Ying, Houqun|Lin, Kang|Peng, Hongxin|Wang, Shukui
PMID: 25778330
Journal: Cancer Med. 2016 Sep;5(9):2544-57.
Title: Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
Author: Tanaka, Genki|Inoue, Ken-Ichi|Shimizu, Takayuki|Akimoto, Kazumi|Kubota, Keiichi
PMID: 27485632
Journal: Environ Mol Mutagen. 2018 Jan;59(1):69-78.
Title: Polymorphisms of xenobiotic-metabolizing genes and colorectal cancer risk in patients with lynch syndrome: A retrospective cohort study in Taiwan.
Author: Kamiza, Abram Bunya|You, Jeng-Fu|Wang, Wen-Chang|Tang, Reiping|Chang, Chun-Yu|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 28714190