Primary Site >> Colorectal Cancer
Gene >> GSTA1
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Ref: The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk. PMID: 11535243 |
Ref: Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer. PMID: 12505289 |
Ref: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. PMID: 12896903 Ref: Genetic polymorphisms and modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in human lymphocytes. PMID: 14601045 |
Ref: Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk. PMID: 15319294 |
Ref: Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients. PMID: 16865249 Ref: Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans. PMID: 16886896 Ref: Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility. PMID: 17010218 Ref: Isothiocyanate iberin modulates phase II enzymes, posttranslational modification of histones and inhibits growth of Caco-2 cells by inducing apoptosis. PMID: 17167713 |
Ref: GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis. PMID: 20207535 |
Ref: Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. PMID: 21256954 Ref: [Analysis of gene expression patterns in an irinotecan-resistance colon cancer cell by cDNA microarray]. PMID: 21355292 Ref: Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients. PMID: 21844655 |
Ref: Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population. PMID: 22697302 Ref: Polymorphisms in heterocyclic aromatic amines metabolism-related genes are associated with colorectal adenoma risk. PMID: 22724046 |
Ref: Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls. PMID: 24245549 |
Ref: Polymorphisms of GSTA1 contribute to elevated cancer risk: evidence from 15 studies. PMID: 25778330 |
Ref: Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells. PMID: 27485632 |
Ref: Polymorphisms of xenobiotic-metabolizing genes and colorectal cancer risk in patients with lynch syndrome: A retrospective cohort study in Taiwan. PMID: 28714190 |