Primary Site >> Colorectal Cancer

Gene >> GRP

Journal: Cancer Res. 1990 Nov 1;50(21):6772-8.
Title: Specific binding and growth effects of bombesin-related peptides on mouse colon cancer cells in vitro.
Author: Narayan, S|Guo, Y S|Townsend, C M Jr|Singh, P
PMID: 2208141
Journal: Hum Cell. 1990 Mar;3(1):23-6.
Title: [Gut hormones with activity to modulate cellular growth].
Author: Yamaguchi, K
PMID: 2083220
Journal: Cell Growth Differ. 1992 Feb;3(2):111-8.
Title: A potent bombesin receptor antagonist inhibits bombesin-stimulated growth of mouse colon cancer cells in vitro: absence of autocrine effects.
Author: Narayan, S|Spindel, E R|Rubin, N H|Singh, P
PMID: 1323998
Journal: Cancer Res. 1992 Mar 1;52(5):1114-22.
Title: Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells.
Author: Frucht, H|Gazdar, A F|Park, J A|Oie, H|Jensen, R T
PMID: 1310640
Journal: Acta Oncol. 1994;33(6):693-701.
Title: Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice.
Author: Radulovic, S|Schally, A V|Reile, H|Halmos, G|Szepeshazi, K|Groot, K|Milovanovic, S|Miller, G|Yano, T
PMID: 7946450
Journal: Br J Cancer. 1995 May;71(5):1087-9.
Title: High-affinity binding sites for gastrin-releasing peptide on human colorectal cancer tissue but not uninvolved mucosa.
Author: Preston, S R|Woodhouse, L F|Jones-Blackett, S|Miller, G V|Primrose, J N
PMID: 7734305
Journal: Oncol Res. 1995;7(12):583-90.
Title: Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II.
Author: Yun, J|Tomida, A|Nagata, K|Tsuruo, T
PMID: 8704275
Journal: Int J Oncol. 1995 Nov;7(5):1167-73.
Title: In-vivo effect of somatostatin analog, lanreotide, and/or grp antagonist, bim-26226, on the growth of colon-cancer peritoneal carcinomatosis in the rat.
Author: Gouyon, B|Reyldesmars, F|Leromancer, M|Pigeon, C|Lewin, M|Lehy, T
PMID: 21552947
Journal: Int J Cancer. 1996 Nov 4;68(3):391-6.
Title: Glucose-regulated stresses induce resistance to camptothecin in human cancer cells.
Author: Tomida, A|Yun, J|Tsuruo, T
PMID: 8903483
Journal: J Clin Invest. 1997 Nov 15;100(10):2530-7.
Title: Constitutive activation of the gastrin-releasing peptide receptor expressed by the nonmalignant human colon epithelial cell line NCM460.
Author: Ferris, H A|Carroll, R E|Rasenick, M M|Benya, R V
PMID: 9366567
Journal: Eur J Cancer. 1999 Jan;35(1):125-32.
Title: High gastrin releasing peptide receptor mRNA level is related to tumour dedifferentiation and lymphatic vessel invasion in human colon cancer.
Author: Saurin, J C|Rouault, J P|Abello, J|Berger, F|Remy, L|Chayvialle, J A
PMID: 10211100
Journal: Am J Physiol. 1999 Mar;276(3 Pt 1):G655-65.
Title: Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans.
Author: Carroll, R E|Matkowskyj, K A|Chakrabarti, S|McDonald, T J|Benya, R V
PMID: 10070042
Journal: Cancer Res. 1999 Feb 15;59(4):962-7.
Title: Bombesin stimulates adhesion, spreading, lamellipodia formation, and proliferation in the human colon carcinoma Isreco1 cell line.
Author: Saurin, J C|Nemoz-Gaillard, E|Sordat, B|Cuber, J C|Coy, D H|Abello, J|Chayvialle, J A
PMID: 10029091
Journal: Br J Cancer. 2000 Jan;82(1):124-30.
Title: Bombesin family receptor and ligand gene expression in human colorectal cancer and normal mucosa.
Author: Chave, H S|Gough, A C|Palmer, K|Preston, S R|Primrose, J N
PMID: 10638978
Journal: Cell Growth Differ. 2000 Jul;11(7):385-93.
Title: Gastrin-releasing peptide is a mitogen and a morphogen in murine colon cancer.
Author: Carroll, R E|Matkowskyj, K A|Tretiakova, M S|Battey, J F|Benya, R V
PMID: 10939592
Journal: Mol Pharmacol. 2000 Sep;58(3):601-7.
Title: Characterization of gastrin-releasing peptide and its receptor aberrantly expressed by human colon cancer cell lines.
Author: Carroll, R E|Ostrovskiy, D|Lee, S|Danilkovich, A|Benya, R V
PMID: 10953054
Journal: J Biol Chem. 2001 Jun 22;276(25):22941-7. Epub 2001 Apr 5.
Title: Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in intestinal epithelial cells.
Author: Guo, Y S|Hellmich, M R|Wen, X D|Townsend, C M Jr
PMID: 11292836
Journal: Mech Dev. 2002 May;113(2):121-30.
Title: Contribution of gastrin-releasing peptide and its receptor to villus development in the murine and human gastrointestinal tract.
Author: Carroll, Robert E|Matkowskyj, Kristina|Saunthararajah, Yogen|Sekosan, Marin|Battey, James F|Benya, Richard V
PMID: 11960700
Journal: Cancer Res. 2002 Aug 15;62(16):4829-35.
Title: Bombesin stimulates invasion and migration of Isreco1 colon carcinoma cells in a Rho-dependent manner.
Author: Saurin, Jean-Christophe|Fallavier, Marjorie|Sordat, Bernard|Gevrey, Jean-Claude|Chayvialle, Jean-Alain|Abello, Jacques
PMID: 12183443
Journal: J Histochem Cytochem. 2003 Feb;51(2):205-14.
Title: Quantitative immunohistochemistry by measuring cumulative signal strength accurately measures receptor number.
Author: Matkowskyj, Kristina A|Cox, Randal|Jensen, Robert T|Benya, Richard V
PMID: 12533529
Journal: J Histochem Cytochem. 2003 Aug;51(8):1041-8.
Title: Expression of GRP and its receptor in well-differentiated colon cancer cells correlates with the presence of focal adhesion kinase phosphorylated at tyrosines 397 and 407.
Author: Matkowskyj, Kristina A|Keller, Kristin|Glover, Sarah|Kornberg, Lori|Tran-Son-Tay, Roger|Benya, Richard V
PMID: 12871985
Journal:
Title: (99m)Tc-(Hydrazinonicotinic acid-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2)(tricine)(TPPTS)
Author: Leung, Kam
PMID: 20641678
Journal: J Cell Physiol. 2004 Apr;199(1):77-88.
Title: Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin-releasing peptide's morphogenic properties.
Author: Glover, Sarah|Delaney, Melissa|Dematte, Cecile|Kornberg, Lori|Frasco, Melissa|Tran-Son-Tay, Roger|Benya, Richard V
PMID: 14978737
Journal: J Mol Neurosci. 2004;22(1-2):75-82.
Title: Transcriptional activation of the human gastrin-releasing peptide receptor gene in gastrointestinal and prostatic epithelial cancer cells.
Author: Qu, Xiangping|Xiao, Dongmei|Weber, H Christian
PMID: 14742912
Journal: Biochem Pharmacol. 2004 Dec 1;68(11):2129-42.
Title: Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.
Author: Patel, Oneel|Dumesny, Chelsea|Giraud, Andrew S|Baldwin, Graham S|Shulkes, Arthur
PMID: 15498503
Journal: Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1274-82.
Title: Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling.
Author: Glover, Sarah|Nathaniel, Rajkumar|Shakir, Lubna|Perrault, Cecile|Anderson, Rebecca K|Tran-Son-Tay, Roger|Benya, Richard V
PMID: 15890713
Journal: Endocrinology. 2006 Jan;147(1):502-9. Epub 2005 Oct 13.
Title: Synthesis, expression and biological activity of the prohormone for gastrin releasing peptide (ProGRP).
Author: Dumesny, Chelsea|Patel, Oneel|Lachal, Shamilah|Giraud, Andrew S|Baldwin, Graham S|Shulkes, Arthur
PMID: 16223866
Journal: J Proteome Res. 2006 Jun;5(6):1460-8.
Title: Consequence of gastrin-releasing peptide receptor activation in a human colon cancer cell line: a proteomic approach.
Author: Ruginis, Tom|Taglia, Lauren|Matusiak, Damien|Lee, Bao-Shiang|Benya, Richard V
PMID: 16739997
Journal: Oncogene. 2007 Feb 15;26(7):958-69. Epub 2006 Aug 14.
Title: Bombesin induces cyclooxygenase-2 expression through the activation of the nuclear factor of activated T cells and enhances cell migration in Caco-2 colon carcinoma cells.
Author: Corral, R S|Iniguez, M A|Duque, J|Lopez-Perez, R|Fresno, M
PMID: 16909108
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G182-90. Epub 2006 Aug
Title: Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase.
Author: Taglia, Lauren|Matusiak, Damien|Matkowskyj, Kristina A|Benya, Richard V
PMID: 16920698
Journal: Endocrinology. 2007 Mar;148(3):1330-9.
Title: C-terminal fragments of the gastrin-releasing peptide precursor stimulate cell proliferation via a novel receptor.
Author: Patel, Oneel|Dumesny, Chelsea|Shulkes, Arthur|Baldwin, Graham S
PMID: 17122080
Journal: Cancer Lett. 2007 Aug 28;254(1):87-93. Epub 2007 Mar 29.
Title: Recombinant C-terminal fragments of the gastrin-releasing peptide precursor are bioactive.
Author: Patel, Oneel|Dumesny, Chelsea|Shulkes, Arthur|Baldwin, Graham S
PMID: 17395367
Journal: Clin Exp Metastasis. 2008;25(4):451-63.
Title: GRP-induced up-regulation of Hsp72 promotes CD16+/94+ natural killer cell binding to colon cancer cells causing tumor cell cytolysis.
Author: Taglia, Lauren|Matusiak, Damien|Benya, Richard V
PMID: 18350254
Journal: Clin Exp Metastasis. 2009;26(7):663-71.
Title: Expression of GRP and its receptor is associated with improved survival in patients with colon cancer.
Author: Rivera, Claudio A|Ahlberg, Ned C|Taglia, Lauren|Kumar, Mayank|Blunier, Adam|Benya, Richard V
PMID: 19430935
Journal: Bioorg Med Chem. 2011 Feb 1;19(3):1085-96.
Title: In vivo MR/optical imaging for gastrin releasing peptide receptor of prostate cancer tumor using Gd-TTDA-NP-BN-Cy5.5.
Author: Lin, Ying-Hsiu|Dayananda, Kasala|Chen, Chiao-Yun|Liu, Gin-Chung|Luo, Tsai-Yueh|Hsu, Hui-Sheng|Wang, Yun-Ming
PMID: 20493715
Journal: Clin Epigenetics. 2011 Aug;2(2):331-8.
Title: Identification of ChIP-seq mapped targets of HP1beta due to bombesin/GRP receptor activation.
Author: Tell, Robert|Wang, Q Tian|Blunier, Adam|Benya, Richard V
PMID: 22704345
Journal: Cancer Biother Radiopharm. 2011 Jun;26(3):309-16.
Title: Preclinical evaluation of a new bombesin analog for imaging of gastrin-releasing peptide receptors.
Author: Shirmardi, Seyed Pezhman|Gandomkar, Mostafa|Maragheh, Mohammad Ghannadi|Shamsaei, Mojtaba
PMID: 21711115
Journal: Am J Pathol. 2011 Feb;178(2):672-8.
Title: Gastrin-releasing peptide signaling alters colon cancer invasiveness via heterochromatin protein 1Hsbeta.
Author: Tell, Robert|Rivera, Claudio A|Eskra, Jillian|Taglia, Lauren N|Blunier, Adam|Wang, Q Tian|Benya, Richard V
PMID: 21281799
Journal: J Cell Biochem. 2011 Feb;112(2):643-52.
Title: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer.
Author: Huang, Ssu-Ming|Cheung, Chi-Wai|Chang, Chih-Shiang|Tang, Chih-Hsin|Liu, Ju-Fang|Lin, Yu-Hsin|Chen, Jia-Hong|Ko, Shihi-Hsun|Wong, Kar-Lok|Lu, Dah-Yuu
PMID: 21268086
Journal: Endocrinology. 2012 Mar;153(3):1082-92.
Title: Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo.
Author: Patel, Oneel|Clyde, Daniel|Chang, Mike|Nordlund, Marianne S|Steel, Rohan|Kemp, Bruce E|Pritchard, D Mark|Shulkes, Arthur|Baldwin, Graham S
PMID: 22202166
Journal: Cell Cycle. 2012 Jul 1;11(13):2518-25.
Title: Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancers.
Author: Rick, Ferenc G|Buchholz, Stefan|Schally, Andrew V|Szalontay, Luca|Krishan, Awtar|Datz, Christian|Stadlmayr, Andreas|Aigner, Elmar|Perez, Roberto|Seitz, Stephan|Block, Norman L|Hohla, Florian
PMID: 22751419
Journal: Mol Pharmacol. 2014 Sep;86(3):252-62.
Title: Galpha13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.
Author: Patel, Maulik|Kawano, Takeharu|Suzuki, Nobuchika|Hamakubo, Takao|Karginov, Andrei V|Kozasa, Tohru
PMID: 24958816
Journal: Bioorg Med Chem. 2016 Nov 15;24(22):5834-5841.
Title: Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor.
Author: Begum, Anjuman Ara|Moyle, Peter M|Toth, Istvan
PMID: 27670095
Journal: Biol Res. 2018 Apr 13;51(1):10.
Title: Independent prognostic genes and mechanism investigation for colon cancer.
Author: Li, Chunsheng|Shen, Zhen|Zhou, Yangyang|Yu, Wei
PMID: 29653552
Journal: Clin Lab. 2018 Jul 1;64(7):1259-1268.
Title: Clinical Application of Pro-Gastrin-Releasing Peptide.
Author: Fang, Lili|Huang, Zhongqiang|Lin, Yongzhi|Fu, Jianguo|Liang, Xianming|Liu, Fan
PMID: 30146822