Primary Site >> Colorectal Cancer
Gene >> GREM1
| 1. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2003 Aug;145(1):70-3. | ||||||||||
| Title: | Allelic imbalance in colorectal cancer at the CRAC1 locus in early-onset colorectal cancer. | ||||||||||
| Author: | Popat, Sanjay|Stone, Joanne|Houlston, Richard S | ||||||||||
| PMID: | 12885466 | ||||||||||
| 2. | |||||||||||
| Journal: | J Cell Biol. 2004 Oct 11;167(1):123-33. Epub 2004 Oct 4. | ||||||||||
| Title: | Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. | ||||||||||
| Author: | Koli, Katri|Wempe, Frank|Sterner-Kock, Anja|Kantola, Anna|Komor, Martina|Hofmann, Wolf-K|von Melchner, Harald|Keski-Oja, Jorma | ||||||||||
| PMID: | 15466481 | ||||||||||
| 3. | |||||||||||
| Journal: | Fam Cancer. 2006;5(3):221-6. | ||||||||||
| Title: | The genetics of FAP and FAP-like syndromes. | ||||||||||
| Author: | Lipton, Lara|Tomlinson, Ian | ||||||||||
| PMID: | 16998667 | ||||||||||
| 4. | |||||||||||
| Journal: | Nat Genet. 2008 Jan;40(1):26-8. Epub 2007 Dec 16. | ||||||||||
| Title: | Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. | ||||||||||
| Author: | Jaeger, Emma|Webb, Emily|Howarth, Kimberley|Carvajal-Carmona, Luis|Rowan, Andrew|Broderick, Peter|Walther, Axel|Spain, Sarah|Pittman, Alan|Kemp, Zoe|Sullivan, Kate|Heinimann, Karl|Lubbe, Steven|Domingo, Enric|Barclay, Ella|Martin, Lynn|Gorman, Maggie|Chan | ||||||||||
| PMID: | 18084292 | ||||||||||
| 5. | |||||||||||
| Journal: | Am J Hum Genet. 2008 Mar;82(3):723-36. | ||||||||||
| Title: | Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. | ||||||||||
| Author: | Daley, Denise|Lewis, Susan|Platzer, Petra|MacMillen, Melissa|Willis, Joseph|Elston, Robert C|Markowitz, Sanford D|Wiesner, Georgia L | ||||||||||
| PMID: | 18313025 | ||||||||||
| 6. | |||||||||||
| Journal: | Micron. 2008 Dec;39(8):1393-7. | ||||||||||
| Title: | Monitoring membrane rafts in colorectal cancer cells by means of correlative fluorescence electron microscopy (CFEM). | ||||||||||
| Author: | Jahn, Kristina A|Braet, Filip | ||||||||||
| PMID: | 18495485 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2835-45. | ||||||||||
| Title: | Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results. | ||||||||||
| Author: | Galamb, Orsolya|Sipos, Ferenc|Solymosi, Norbert|Spisak, Sandor|Krenacs, Tibor|Toth, Kinga|Tulassay, Zsolt|Molnar, Bela | ||||||||||
| PMID: | 18843029 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1934-6. | ||||||||||
| Title: | No breast cancer association for transforming growth factor-beta pathway colorectal cancer single nucleotide polymorphisms. | ||||||||||
| Author: | Gibson, Lorna|Johnson, Nichola|Fraser, Agnes|dos Santos Silva, Isabel|Houlston, Richard|Peto, Julian|Fletcher, Olivia | ||||||||||
| PMID: | 19505925 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Treat Res. 2010;155:85-103. | ||||||||||
| Title: | Tgf-beta signaling alterations and colon cancer. | ||||||||||
| Author: | Bellam, Naresh|Pasche, Boris | ||||||||||
| PMID: | 20517689 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Cancer. 2011 Oct 1;129(7):1635-42. | ||||||||||
| Title: | Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients. | ||||||||||
| Author: | Venkatachalam, Ramprasath|Verwiel, Eugene T P|Kamping, Eveline J|Hoenselaar, Eveline|Gorgens, Heike|Schackert, Hans K|van Krieken, J Han J M|Ligtenberg, Marjolijn J L|Hoogerbrugge, Nicoline|van Kessel, Ad Geurts|Kuiper, Roland P | ||||||||||
| PMID: | 21128281 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS Genet. 2011 Jun;7(6):e1002105. | ||||||||||
| Title: | Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. | ||||||||||
| Author: | Tomlinson, Ian P M|Carvajal-Carmona, Luis G|Dobbins, Sara E|Tenesa, Albert|Jones, Angela M|Howarth, Kimberley|Palles, Claire|Broderick, Peter|Jaeger, Emma E M|Farrington, Susan|Lewis, Annabelle|Prendergast, James G D|Pittman, Alan M|Theodoratou, Evropi|Ol | ||||||||||
| PMID: | 21655089 | ||||||||||
| 12. | |||||||||||
| Journal: | Nat Genet. 2012 May 6;44(6):699-703. | ||||||||||
| Title: | Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1. | ||||||||||
| Author: | Jaeger, Emma|Leedham, Simon|Lewis, Annabelle|Segditsas, Stefania|Becker, Martin|Cuadrado, Pedro Rodenas|Davis, Hayley|Kaur, Kulvinder|Heinimann, Karl|Howarth, Kimberley|East, James|Taylor, Jenny|Thomas, Huw|Tomlinson, Ian | ||||||||||
| PMID: | 22561515 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2012;7(11):e48547. | ||||||||||
| Title: | Dysplasia-carcinoma transition specific transcripts in colonic biopsy samples. | ||||||||||
| Author: | Galamb, Orsolya|Wichmann, Barnabas|Sipos, Ferenc|Spisak, Sandor|Krenacs, Tibor|Toth, Kinga|Leiszter, Katalin|Kalmar, Alexandra|Tulassay, Zsolt|Molnar, Bela | ||||||||||
| PMID: | 23155391 | ||||||||||
| 14. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e42407. | ||||||||||
| Title: | Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese. | ||||||||||
| Author: | Thean, Lai Fun|Li, Hui Hua|Teo, Yik Ying|Koh, Woon-Puay|Yuan, Jian-Min|Teoh, Mei Lin|Koh, Poh Koon|Tang, Choong Leong|Cheah, Peh Yean | ||||||||||
| PMID: | 22879968 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Res. 2012 Apr 15;72(8):2036-44. | ||||||||||
| Title: | Characterization of gene-environment interactions for colorectal cancer susceptibility loci. | ||||||||||
| Author: | Hutter, Carolyn M|Chang-Claude, Jenny|Slattery, Martha L|Pflugeisen, Bethann M|Lin, Yi|Duggan, David|Nan, Hongmei|Lemire, Mathieu|Rangrej, Jagadish|Figueiredo, Jane C|Jiao, Shuo|Harrison, Tabitha A|Liu, Yan|Chen, Lin S|Stelling, Deanna L|Warnick, Greg S|H | ||||||||||
| PMID: | 22367214 | ||||||||||
| 16. | |||||||||||
| Journal: | Methods. 2013 Jan;59(1):S16-9. | ||||||||||
| Title: | Gene expression analysis of normal and colorectal cancer tissue samples from fresh frozen and matched formalin-fixed, paraffin-embedded (FFPE) specimens after manual and automated RNA isolation. | ||||||||||
| Author: | Kalmar, Alexandra|Wichmann, Barnabas|Galamb, Orsolya|Spisak, Sandor|Toth, Kinga|Leiszter, Katalin|Tulassay, Zsolt|Molnar, Bela | ||||||||||
| PMID: | 23036325 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Oncol. 2013 Aug;7(4):826-39. | ||||||||||
| Title: | Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1. | ||||||||||
| Author: | Karagiannis, George S|Berk, Aaron|Dimitromanolakis, Apostolos|Diamandis, Eleftherios P | ||||||||||
| PMID: | 23659962 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2014 Feb 24;9(2):e89736. | ||||||||||
| Title: | Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk. | ||||||||||
| Author: | Yang, Hua|Gao, Ya|Feng, Tian|Jin, Tian-Bo|Kang, Long-Li|Chen, Chao | ||||||||||
| PMID: | 24586997 | ||||||||||
| 19. | |||||||||||
| Journal: | Carcinogenesis. 2014 Sep;35(9):2025-30. | ||||||||||
| Title: | Shared and independent colorectal cancer risk alleles in TGFbeta-related genes in African and European Americans. | ||||||||||
| Author: | Kupfer, Sonia S|Skol, Andrew D|Hong, Ellie|Ludvik, Anton|Kittles, Rick A|Keku, Temitope O|Sandler, Robert S|Ellis, Nathan A | ||||||||||
| PMID: | 24753543 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Oncol. 2014 Oct;8(7):1240-52. | ||||||||||
| Title: | Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts. | ||||||||||
| Author: | Karagiannis, George S|Treacy, Ann|Messenger, David|Grin, Andrea|Kirsch, Richard|Riddell, Robert H|Diamandis, Eleftherios P | ||||||||||
| PMID: | 24812030 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Rep. 2014 Aug 21;8(4):983-90. | ||||||||||
| Title: | A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding. | ||||||||||
| Author: | Lewis, Annabelle|Freeman-Mills, Luke|de la Calle-Mustienes, Elisa|Giraldez-Perez, Rosa Maria|Davis, Hayley|Jaeger, Emma|Becker, Martin|Hubner, Nina C|Nguyen, Luan N|Zeron-Medina, Jorge|Bond, Gareth|Stunnenberg, Hendrik G|Carvajal, Jaime J|Gomez-Skarmeta, | ||||||||||
| PMID: | 25131200 | ||||||||||
| 22. | |||||||||||
| Journal: | Biol Chem. 2015 Feb;396(2):163-83. | ||||||||||
| Title: | Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression. | ||||||||||
| Author: | Karagiannis, George S|Musrap, Natasha|Saraon, Punit|Treacy, Ann|Schaeffer, David F|Kirsch, Richard|Riddell, Robert H|Diamandis, Eleftherios P | ||||||||||
| PMID: | 25153376 | ||||||||||
| 23. | |||||||||||
| Journal: | Diagn Pathol. 2015 Jul 25;10:126. | ||||||||||
| Title: | Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples. | ||||||||||
| Author: | Kalmar, Alexandra|Wichmann, Barnabas|Galamb, Orsolya|Spisak, Sandor|Toth, Kinga|Leiszter, Katalin|Nielsen, Boye Schnack|Bartak, Barbara Kinga|Tulassay, Zsolt|Molnar, Bela | ||||||||||
| PMID: | 26208990 | ||||||||||
| 24. | |||||||||||
| Journal: | Ann Clin Biochem. 2015 Nov;52(Pt 6):690-2. | ||||||||||
| Title: | The Mendelian colorectal cancer syndromes. | ||||||||||
| Author: | Tomlinson, Ian | ||||||||||
| PMID: | 26169059 | ||||||||||
| 25. | |||||||||||
| Journal: | Genet Res (Camb). 2015 May 20;97:e11. | ||||||||||
| Title: | GREM1 germline mutation screening in Ashkenazi Jewish patients with familial colorectal cancer. | ||||||||||
| Author: | Laitman, Yael|Jaeger, Emma|Katz, Lior|Tomlinson, Ian|Friedman, Eitan | ||||||||||
| PMID: | 25992589 | ||||||||||
| 26. | |||||||||||
| Journal: | Dig Surg. 2015;32(3):159-65. | ||||||||||
| Title: | Flattened tumor requires a more careful attention for residual distal cancer spread in locally advanced lower rectal carcinoma after chemoradiotherapy. | ||||||||||
| Author: | Kinoshita, Osamu|Nakanishi, Masayoshi|Murayama, Yasutoshi|Kuriu, Yoshiaki|Kokuba, Yukihito|Otsuji, Eigo | ||||||||||
| PMID: | 25833218 | ||||||||||
| 27. | |||||||||||
| Journal: | Nat Med. 2015 Jan;21(1):62-70. | ||||||||||
| Title: | Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. | ||||||||||
| Author: | Davis, Hayley|Irshad, Shazia|Bansal, Mukesh|Rafferty, Hannah|Boitsova, Tatjana|Bardella, Chiara|Jaeger, Emma|Lewis, Annabelle|Freeman-Mills, Luke|Giner, Francesc Castro|Rodenas-Cuadrado, Pedro|Mallappa, Sreelakshmi|Clark, Susan|Thomas, Huw|Jeffery, Rosema | ||||||||||
| PMID: | 25419707 | ||||||||||
| 28. | |||||||||||
| Journal: | Proteomics. 2015 Jan;15(1):77-88. | ||||||||||
| Title: | Impact of the mitogen-activated protein kinase pathway on the subproteome of detergent-resistant microdomains of colon carcinoma cells. | ||||||||||
| Author: | Recktenwald, Christian V|Lichtenfels, Rudolf|Wulfaenger, Jens|Muller, Anja|Dressler, Sven P|Seliger, Barbara | ||||||||||
| PMID: | 25359454 | ||||||||||
| 29. | |||||||||||
| Journal: | Int J Colorectal Dis. 2015 Aug;30(8):1081-9. | ||||||||||
| Title: | Role of intraoperative frozen section for assessing distal resection margin after anterior resection. | ||||||||||
| Author: | Gomes, Rachel M|Bhandare, Manish|Desouza, Ashwin|Bal, Munita|Saklani, Avanish P | ||||||||||
| PMID: | 25982468 | ||||||||||
| 30. | |||||||||||
| Journal: | Tumour Biol. 2016 Feb;37(2):2243-55. | ||||||||||
| Title: | BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice. | ||||||||||
| Author: | Karagiannis, George S|Afaloniati, Hara|Karamanavi, Elisavet|Poutahidis, Theofilos|Angelopoulou, Katerina | ||||||||||
| PMID: | 26358253 | ||||||||||
| 31. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2016 Jan;55(1):95-106. | ||||||||||
| Title: | GREM1 and POLE variants in hereditary colorectal cancer syndromes. | ||||||||||
| Author: | Rohlin, Anna|Eiengard, Frida|Lundstam, Ulf|Zagoras, Theofanis|Nilsson, Staffan|Edsjo, Anders|Pedersen, Jan|Svensson, Janhenry|Skullman, Stefan|Karlsson, B Goran|Bjork, Jan|Nordling, Margareta | ||||||||||
| PMID: | 26493165 | ||||||||||
| 32. | |||||||||||
| Journal: | Genet Res (Camb). 2016 Mar 7;98:e5. | ||||||||||
| Title: | Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations. | ||||||||||
| Author: | Ziai, James|Matloff, Ellen|Choi, Jaehyuk|Kombo, Ninani|Materin, Miguel|Bale, Allen E | ||||||||||
| PMID: | 26947005 | ||||||||||
| 33. | |||||||||||
| Journal: | Gastroenterology. 2017 Jun;152(8):1876-1880.e1. | ||||||||||
| Title: | Features of Patients With Hereditary Mixed Polyposis Syndrome Caused by Duplication of GREM1 and Implications for Screening and Surveillance. | ||||||||||
| Author: | Lieberman, Sari|Walsh, Tom|Schechter, Menachem|Adar, Tomer|Goldin, Eran|Beeri, Rachel|Sharon, Nitzan|Baris, Hagit|Ben Avi, Liat|Half, Elizabeth|Lerer, Israela|Shirts, Brian H|Pritchard, Colin C|Tomlinson, Ian|King, Mary-Claire|Levy-Lahad, Ephrat|Peretz, T | ||||||||||
| PMID: | 28242209 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncotarget. 2017 May 23;8(37):61318-61326. | ||||||||||
| Title: | A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site. | ||||||||||
| Author: | Li, Jiaoyuan|Liu, Hui|Zou, Li|Ke, Juntao|Zhang, Yi|Zhu, Ying|Yang, Yang|Gong, Yajie|Tian, Jianbo|Zou, Danyi|Peng, Xiating|Gong, Jing|Zhong, Rong|Huang, Kun|Chang, Jiang|Miao, Xiaoping | ||||||||||
| PMID: | 28977865 | ||||||||||
| 35. | |||||||||||
| Journal: | Int J Surg. 2017 Mar;39:1-10. | ||||||||||
| Title: | Laparoscopic versus open surgery for rectal cancer: A meta-analysis of classic randomized controlled trials and high-quality Nonrandomized Studies in the last 5 years. | ||||||||||
| Author: | Chen, Ke|Cao, Guodong|Chen, Bo|Wang, Mingqing|Xu, Xingyu|Cai, Wenwen|Xu, Yicheng|Xiong, Maoming | ||||||||||
| PMID: | 28087370 | ||||||||||
| 36. | |||||||||||
| Journal: | Hum Pathol. 2017 Apr;62:56-65. | ||||||||||
| Title: | Prognostic significance of stromal GREM1 expression in colorectal cancer. | ||||||||||
| Author: | Jang, Bo Gun|Kim, Hye Sung|Chang, Weon Young|Bae, Jeong Mo|Oh, Hyeon Jeong|Wen, Xianyu|Jeong, Seorin|Cho, Nam Yun|Kim, Woo Ho|Kang, Gyeong Hoon | ||||||||||
| PMID: | 28041973 | ||||||||||
| 37. | |||||||||||
| Journal: | Surg Endosc. 2018 May;32(5):2442-2447. | ||||||||||
| Title: | Transanal total mesorectal excision: pathological results of 186 patients with mid and low rectal cancer. | ||||||||||
| Author: | de Lacy, F Borja|van Laarhoven, Jacqueline J E M|Pena, Romina|Arroyave, Maria Clara|Bravo, Raquel|Cuatrecasas, Miriam|Lacy, Antonio M | ||||||||||
| PMID: | 29101570 | ||||||||||
| 38. | |||||||||||
| Journal: | Sci Rep. 2018 Feb 16;8(1):3161. | ||||||||||
| Title: | Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations. | ||||||||||
| Author: | Druliner, Brooke R|Wang, Panwen|Bae, Taejeong|Baheti, Saurabh|Slettedahl, Seth|Mahoney, Douglas|Vasmatzis, Nikolaos|Xu, Hang|Kim, Minsoo|Bockol, Matthew|O'Brien, Daniel|Grill, Diane|Warner, Nathaniel|Munoz-Gomez, Miguel|Kossick, Kimberlee|Johnson, Ruth|Mo | ||||||||||
| PMID: | 29453410 | ||||||||||
| 39. | |||||||||||
| Journal: | BMC Genomics. 2018 Feb 9;19(Suppl 3):113. | ||||||||||
| Title: | HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer. | ||||||||||
| Author: | Pudova, Elena A|Kudryavtseva, Anna V|Fedorova, Maria S|Zaretsky, Andrew R|Shcherbo, Dmitry S|Lukyanova, Elena N|Popov, Anatoly Y|Sadritdinova, Asiya F|Abramov, Ivan S|Kharitonov, Sergey L|Krasnov, George S|Klimina, Kseniya M|Koroban, Nadezhda V|Volchenko, | ||||||||||
| PMID: | 29504907 | ||||||||||
| 40. | |||||||||||
| Journal: | Fam Cancer. 2018 May 26. pii: 10.1007/s10689-018-0090-6. | ||||||||||
| Title: | Identification of a novel GREM1 duplication in a patient with multiple colon polyps. | ||||||||||
| Author: | McKenna, Danielle B|Van Den Akker, Jeroen|Zhou, Alicia Y|Ryan, Lauren|Leon, Annette|O'Connor, Robert|Shah, Payal D|Rustgi, Anil K|Katona, Bryson W | ||||||||||
| PMID: | 29804199 | ||||||||||
| 41. | |||||||||||
| Journal: | Am J Surg. 2018 Jun 19. pii: S0002-9610(18)30323-4. | ||||||||||
| Title: | Meta-analysis of histopathological outcomes of laparoscopic assisted rectal resection (LARR) vs open rectal resection (ORR) for carcinoma. | ||||||||||
| Author: | Memon, Muhammed Ashraf|Awaiz, Aiman|Yunus, Rossita Mohamad|Memon, Breda|Khan, Shahjahan | ||||||||||
| PMID: | 29958656 | ||||||||||
| 42. | |||||||||||
| Journal: | Ann Surg Oncol. 2018 Oct;25(11):3171-3178. | ||||||||||
| Title: | Defining Non-inferiority Margins for Quality of Surgical Resection for Rectal Cancer: A Delphi Consensus Study. | ||||||||||
| Author: | Acuna, Sergio A|Chesney, Tyler R|Amarasekera, Sonali T|Baxter, Nancy N | ||||||||||
| PMID: | 30051366 | ||||||||||
| 43. | |||||||||||
| Journal: | PLoS One. 2018 Oct 9;13(10):e0204887. | ||||||||||
| Title: | Surgical resection for rectal cancer. Is laparoscopic surgery as successful as open approach? A systematic review with meta-analysis. | ||||||||||
| Author: | Milone, Marco|Manigrasso, Michele|Burati, Morena|Velotti, Nunzio|Milone, Francesco|De Palma, Giovanni Domenico | ||||||||||
| PMID: | 30300377 | ||||||||||