Primary Site >> Colorectal Cancer
Gene >> GREM1
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Ref: Allelic imbalance in colorectal cancer at the CRAC1 locus in early-onset colorectal cancer. PMID: 12885466 |
Ref: Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. PMID: 15466481 |
Ref: The genetics of FAP and FAP-like syndromes. PMID: 16998667 |
Ref: Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. PMID: 18084292 Ref: Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. PMID: 18313025 Ref: Monitoring membrane rafts in colorectal cancer cells by means of correlative fluorescence electron microscopy (CFEM). PMID: 18495485 Ref: Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results. PMID: 18843029 |
Ref: No breast cancer association for transforming growth factor-beta pathway colorectal cancer single nucleotide polymorphisms. PMID: 19505925 |
Ref: Tgf-beta signaling alterations and colon cancer. PMID: 20517689 |
Ref: Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients. PMID: 21128281 Ref: Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PMID: 21655089 |
Ref: Characterization of gene-environment interactions for colorectal cancer susceptibility loci. PMID: 22367214 Ref: Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1. PMID: 22561515 Ref: Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese. PMID: 22879968 Ref: Dysplasia-carcinoma transition specific transcripts in colonic biopsy samples. PMID: 23155391 |
Ref: Gene expression analysis of normal and colorectal cancer tissue samples from fresh frozen and matched formalin-fixed, paraffin-embedded (FFPE) specimens after manual and automated RNA isolation. PMID: 23036325 Ref: Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1. PMID: 23659962 |
Ref: Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk. PMID: 24586997 Ref: Shared and independent colorectal cancer risk alleles in TGFbeta-related genes in African and European Americans. PMID: 24753543 Ref: Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts. PMID: 24812030 Ref: A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding. PMID: 25131200 |
Ref: Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression. PMID: 25153376 Ref: Impact of the mitogen-activated protein kinase pathway on the subproteome of detergent-resistant microdomains of colon carcinoma cells. PMID: 25359454 Ref: Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. PMID: 25419707 Ref: Flattened tumor requires a more careful attention for residual distal cancer spread in locally advanced lower rectal carcinoma after chemoradiotherapy. PMID: 25833218 Ref: Role of intraoperative frozen section for assessing distal resection margin after anterior resection. PMID: 25982468 Ref: GREM1 germline mutation screening in Ashkenazi Jewish patients with familial colorectal cancer. PMID: 25992589 Ref: The Mendelian colorectal cancer syndromes. PMID: 26169059 Ref: Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples. PMID: 26208990 |
Ref: BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice. PMID: 26358253 Ref: GREM1 and POLE variants in hereditary colorectal cancer syndromes. PMID: 26493165 Ref: Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations. PMID: 26947005 |
Ref: Prognostic significance of stromal GREM1 expression in colorectal cancer. PMID: 28041973 Ref: Laparoscopic versus open surgery for rectal cancer: A meta-analysis of classic randomized controlled trials and high-quality Nonrandomized Studies in the last 5 years. PMID: 28087370 Ref: Features of Patients With Hereditary Mixed Polyposis Syndrome Caused by Duplication of GREM1 and Implications for Screening and Surveillance. PMID: 28242209 Ref: A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site. PMID: 28977865 |
Ref: Transanal total mesorectal excision: pathological results of 186 patients with mid and low rectal cancer. PMID: 29101570 Ref: Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations. PMID: 29453410 Ref: HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer. PMID: 29504907 Ref: Identification of a novel GREM1 duplication in a patient with multiple colon polyps. PMID: 29804199 Ref: Meta-analysis of histopathological outcomes of laparoscopic assisted rectal resection (LARR) vs open rectal resection (ORR) for carcinoma. PMID: 29958656 Ref: Defining Non-inferiority Margins for Quality of Surgical Resection for Rectal Cancer: A Delphi Consensus Study. PMID: 30051366 Ref: Surgical resection for rectal cancer. Is laparoscopic surgery as successful as open approach? A systematic review with meta-analysis. PMID: 30300377 |