Primary Site >> Colorectal Cancer
Gene >> GRB2
| 1. | |||||||||||
| Journal: | Clin Cancer Res. 1998 Apr;4(4):821-8. | ||||||||||
| Title: | Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications. | ||||||||||
| Author: | Ciardiello, F|Tortora, G | ||||||||||
| PMID: | 9563874 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2000 Apr 6;19(15):1901-14. | ||||||||||
| Title: | Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells. | ||||||||||
| Author: | Yang, H|Jiang, D|Li, W|Liang, J|Gentry, L E|Brattain, M G | ||||||||||
| PMID: | 10773880 | ||||||||||
| 3. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2003 May;129(5):272-8. Epub 2003 May 14. | ||||||||||
| Title: | Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells. | ||||||||||
| Author: | Ukegawa, J-I|Takeuchi, Y|Kusayanagi, S|Mitamura, K | ||||||||||
| PMID: | 12748850 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2004 Apr 1;64(7):2601-9. | ||||||||||
| Title: | Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. | ||||||||||
| Author: | Jackson, James G|St Clair, Patricia|Sliwkowski, Mark X|Brattain, Michael G | ||||||||||
| PMID: | 15059917 | ||||||||||
| 5. | |||||||||||
| Journal: | Biochem J. 2006 Mar 15;394(Pt 3):647-56. | ||||||||||
| Title: | Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling. | ||||||||||
| Author: | Kato, Kengo|Shiga, Kiyoto|Yamaguchi, Kazunori|Hata, Keiko|Kobayashi, Toshimitsu|Miyazaki, Kaoru|Saijo, Shigeru|Miyagi, Taeko | ||||||||||
| PMID: | 16241905 | ||||||||||
| 6. | |||||||||||
| Journal: | Carcinogenesis. 2008 Mar;29(3):647-55. | ||||||||||
| Title: | Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells. | ||||||||||
| Author: | Seiden-Long, Isolde|Navab, Roya|Shih, Warren|Li, Ming|Chow, Jane|Zhu, Chang Qi|Radulovich, Nikolina|Saucier, Caroline|Tsao, Ming-Sound | ||||||||||
| PMID: | 18192688 | ||||||||||
| 7. | |||||||||||
| Journal: | Neurosignals. 2008;16(2-3):235-45. | ||||||||||
| Title: | Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. | ||||||||||
| Author: | Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng | ||||||||||
| PMID: | 18253061 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncol Rep. 2008 May;19(5):1191-204. | ||||||||||
| Title: | New insight into the key proteins and pathways involved in the metastasis of colorectal carcinoma. | ||||||||||
| Author: | Yu, Guan-Zhen|Chen, Ying|Long, Ya-Qiu|Dong, Dong|Mu, Xiao-Lan|Wang, Jie-jun | ||||||||||
| PMID: | 18425376 | ||||||||||
| 9. | |||||||||||
| Journal: | J Agric Food Chem. 2010 Mar 10;58(5):2935-42. | ||||||||||
| Title: | Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. | ||||||||||
| Author: | Lai, Kuang-Chi|Huang, An-Cheng|Hsu, Shu-Chun|Kuo, Chao-Lin|Yang, Jai-Sing|Wu, Shin-Hwar|Chung, Jing-Gung | ||||||||||
| PMID: | 20136087 | ||||||||||
| 10. | |||||||||||
| Journal: | Genes Cells. 2010 Jun;15(7):711-724. | ||||||||||
| Title: | Extracellular domain dependence of PTPalpha transforming activity. | ||||||||||
| Author: | Tremper-Wells, Barbara|Resnick, Ross J|Zheng, Xinmin|Holsinger, Leslie J|Shalloway, David | ||||||||||
| PMID: | 20545765 | ||||||||||
| 11. | |||||||||||
| Journal: | J Agric Food Chem. 2010 Oct 27;58(20):11148-55. | ||||||||||
| Title: | Phenethyl isothiocyanate inhibited tumor migration and invasion via suppressing multiple signal transduction pathways in human colon cancer HT29 cells. | ||||||||||
| Author: | Lai, Kuang-Chi|Hsu, Shu-Chun|Kuo, Chao-Lin|Ip, Siu-Wan|Yang, Jai-Sing|Hsu, Yuan-Man|Huang, Hui-Ying|Wu, Shin-Hwar|Chung, Jing-Gung | ||||||||||
| PMID: | 20863062 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106. | ||||||||||
| Title: | Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells. | ||||||||||
| Author: | Colin, Didier|Limagne, Emeric|Jeanningros, Sylvie|Jacquel, Arnaud|Lizard, Gerard|Athias, Anne|Gambert, Philippe|Hichami, Aziz|Latruffe, Norbert|Solary, Eric|Delmas, Dominique | ||||||||||
| PMID: | 21467134 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Cell Proteomics. 2011 Oct;10(10):M110.005397. | ||||||||||
| Title: | Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells. | ||||||||||
| Author: | Lei, Yunlong|Huang, Kai|Gao, Cong|Lau, Quek Choon|Pan, Hua|Xie, Ke|Li, Jingyi|Liu, Rui|Zhang, Tao|Xie, Na|Nai, Huey Shan|Wu, Hong|Dong, Qiang|Zhao, Xia|Nice, Edouard C|Huang, Canhua|Wei, Yuquan | ||||||||||
| PMID: | 21622897 | ||||||||||
| 14. | |||||||||||
| Journal: | Methods. 2012 Feb;56(2):293-304. | ||||||||||
| Title: | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. | ||||||||||
| Author: | Tauro, Bow J|Greening, David W|Mathias, Rommel A|Ji, Hong|Mathivanan, Suresh|Scott, Andrew M|Simpson, Richard J | ||||||||||
| PMID: | 22285593 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Cancer. 2013 Jul;133(1):43-57. | ||||||||||
| Title: | Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis. | ||||||||||
| Author: | Basu Roy, Upal K|Henkhaus, Rebecca S|Loupakis, Fotios|Cremolini, Chiara|Gerner, Eugene W|Ignatenko, Natalia A | ||||||||||
| PMID: | 23280667 | ||||||||||
| 16. | |||||||||||
| Journal: | Gut. 2014 Sep;63(9):1457-67. | ||||||||||
| Title: | Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma. | ||||||||||
| Author: | Chang, Wenjun|Gao, Xianhua|Han, Yifang|Du, Yan|Liu, Qizhi|Wang, Lei|Tan, Xiaojie|Zhang, Qi|Liu, Yan|Zhu, Yan|Yu, Yongwei|Fan, Xinjuan|Zhang, Hongwei|Zhou, Weiping|Wang, Jianping|Fu, Chuangang|Cao, Guangwen | ||||||||||
| PMID: | 24173294 | ||||||||||
| 17. | |||||||||||
| Journal: | BMC Cancer. 2014 Apr 4;14:240. | ||||||||||
| Title: | Met receptor-induced Grb2 or Shc signals both promote transformation of intestinal epithelial cells, albeit they are required for distinct oncogenic functions. | ||||||||||
| Author: | Pomerleau, Veronique|Landry, Melissa|Bernier, Jimmy|Vachon, Pierre H|Saucier, Caroline | ||||||||||
| PMID: | 24708867 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer. 2014 Apr 29;13:95. | ||||||||||
| Title: | SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1. | ||||||||||
| Author: | Qu, Yingying|Chen, Qin|Lai, Xueping|Zhu, Changhong|Chen, Cheng|Zhao, Xian|Deng, Rong|Xu, Ming|Yuan, Haihua|Wang, Yanli|Yu, Jianxiu|Huang, Jian | ||||||||||
| PMID: | 24775912 | ||||||||||
| 19. | |||||||||||
| Journal: | Ann Surg Oncol. 2014 Dec;21 Suppl 4:S743-9. | ||||||||||
| Title: | Clinical significance of GAB2, a scaffolding/docking protein acting downstream of EGFR in human colorectal cancer. | ||||||||||
| Author: | Matsumura, Tae|Sugimachi, Keishi|Takahashi, Yusuke|Uchi, Ryutaro|Sawada, Genta|Ueda, Masami|Hirata, Hidenari|Sakimura, Shotaro|Ueo, Hiroki|Takano, Yuki|Kurashige, Junji|Shinden, Yoshiaki|Eguchi, Hidetoshi|Sudo, Tomoya|Yamamoto, Hirofumi|Doki, Yuichiro|Mor | ||||||||||
| PMID: | 25029990 | ||||||||||
| 20. | |||||||||||
| Journal: | Environ Toxicol. 2015 Jul;30(7):852-63. | ||||||||||
| Title: | Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. | ||||||||||
| Author: | Ma, Yi-Shih|Hsiao, Yu-Ping|Lin, Ju-Hwa|Hsu, Shu-Chun|Chueh, Fu-Shin|Weng, Shu-Wen|Lai, Kuang-Chi|Lin, Jaung-Geng|Chung, Jing-Gung | ||||||||||
| PMID: | 24497447 | ||||||||||
| 21. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Mar 1;8(3):2779-86. eCollection 2015. | ||||||||||
| Title: | Gab2 is a novel prognostic factor for colorectal cancer patients. | ||||||||||
| Author: | Ding, Chenbo|Luo, Junmin|Yu, Weina|Gao, Shaoying|Yang, Liwen|Chen, Chao|Feng, Jihong | ||||||||||
| PMID: | 26045784 | ||||||||||
| 22. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2016 Jan 12;35:5. | ||||||||||
| Title: | Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer. | ||||||||||
| Author: | Ding, Chenbo|Luo, Junmin|Li, Longmei|Li, Shanshan|Yang, Liwen|Pan, Hongfei|Liu, Qianyi|Qin, Huan|Chen, Chao|Feng, Jihong | ||||||||||
| PMID: | 26754532 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Res. 2016 Feb 15;76(4):855-65. | ||||||||||
| Title: | NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells. | ||||||||||
| Author: | Joo, Jung Hee|Oh, Hyunjin|Kim, Myungjin|An, Eun Jung|Kim, Rae-Kwon|Lee, So-Young|Kang, Dong Hoon|Kang, Sang Won|Keun Park, Cheol|Kim, Hoguen|Lee, Su-Jae|Lee, Daekee|Seol, Jae Hong|Bae, Yun Soo | ||||||||||
| PMID: | 26781991 | ||||||||||
| 24. | |||||||||||
| Journal: | Tumour Biol. 2016 Sep;37(9):12153-12160. | ||||||||||
| Title: | SH3GL1 inhibition reverses multidrug resistance in colorectal cancer cells by downregulation of MDR1/P-glycoprotein via EGFR/ERK/AP-1 pathway. | ||||||||||
| Author: | Guan, Haitao|Zhao, Ping|Dai, Zhijun|Liu, Xiaoxu|Wang, Xijing | ||||||||||
| PMID: | 27220321 | ||||||||||
| 25. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2017 Apr 18;36(1):56. | ||||||||||
| Title: | Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels. | ||||||||||
| Author: | Ding, Chenbo|Luo, Junmin|Fan, Xiaobo|Li, Longmei|Li, Shanshan|Wen, Kunming|Feng, Jihong|Wu, Guoqiu | ||||||||||
| PMID: | 28420432 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncogene. 2018 Mar;37(12):1576-1593. | ||||||||||
| Title: | BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. | ||||||||||
| Author: | Herr, Ricarda|Halbach, Sebastian|Heizmann, Miriam|Busch, Hauke|Boerries, Melanie|Brummer, Tilman | ||||||||||
| PMID: | 29326440 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Mol Med. 2018 Jul;42(1):368-380. | ||||||||||
| Title: | Inflammatory genes are novel prognostic biomarkers for colorectal cancer. | ||||||||||
| Author: | Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo | ||||||||||
| PMID: | 29693170 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncol Rep. 2018 Jul;40(1):554-564. | ||||||||||
| Title: | MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2. | ||||||||||
| Author: | Li, Jibin|Xu, Jian|Yan, Xiaofei|Jin, Keer|Li, Wenya|Zhang, Rui | ||||||||||
| PMID: | 29781037 | ||||||||||
| 29. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2018 Sep 10;503(3):2028-2032. | ||||||||||
| Title: | LncRNA snaR upregulates GRB2-associated binding protein 2 and promotes proliferation of ovarian carcinoma cells. | ||||||||||
| Author: | Huang, Yiping|Hu, Yingying|Jin, Zujian|Shen, Zhaojun | ||||||||||
| PMID: | 30093110 | ||||||||||