Primary Site >> Colorectal Cancer

Gene >> GPX2

Journal: Biomed Environ Sci. 1997 Sep;10(2-3):156-62.
Title: Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPX-GI.
Author: Chu, F F|Esworthy, R S|Ho, Y S|Bermeister, M|Swiderek, K|Elliott, R W
PMID: 9315306
Journal: Biophys J. 2002 Aug;83(2):836-48.
Title: Fluid shear regulates the kinetics and molecular mechanisms of activation-dependent platelet binding to colon carcinoma cells.
Author: McCarty, Owen J T|Jadhav, Sameer|Burdick, Monica M|Bell, William R|Konstantopoulos, Konstantinos
PMID: 12124268
Journal: Int J Oncol. 2004 Oct;25(4):1049-56.
Title: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Author: Solmi, Rossella|De Sanctis, Paola|Zucchini, Cinzia|Ugolini, Giampaolo|Rosati, Giancarlo|Del Governatore, Marco|Coppola, Domenico|Yeatman, Thymothy J|Lenzi, Luca|Caira, Antonello|Zanotti, Simone|Taffurelli, Mario|Carinci, Paolo|Valvassori, Luisa|Strippoli,
PMID: 15375555
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):437-43.
Title: Clinicopathologic correlation of up-regulated genes identified using cDNA microarray and real-time reverse transcription-PCR in human colorectal cancer.
Author: Chiu, Sou-Tyau|Hsieh, Fon-Jou|Chen, Shi-Wen|Chen, Chun-Lieh|Shu, Hwei-Fan|Li, Hung
PMID: 15734970
Journal: Biochem Pharmacol. 2005 Sep 15;70(6):888-93.
Title: Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon.
Author: Drew, Janice E|Arthur, John R|Farquharson, Andrew J|Russell, Wendy R|Morrice, Philip C|Duthie, Garry G
PMID: 16038882
Journal: FEBS Lett. 2005 Nov 7;579(27):6135-9. Epub 2005 Oct 11.
Title: Novel sites of cytosolic glutathione peroxidase expression in colon.
Author: Drew, Janice E|Farquharson, Andrew J|Arthur, John R|Morrice, Philip C|Duthie, Garry G
PMID: 16229841
Journal: Cancer Lett. 2008 Feb 8;259(2):218-30.
Title: Aberrant expression of selenoproteins in the progression of colorectal cancer.
Author: Murawaki, Yoshiyuki|Tsuchiya, Hiroyuki|Kanbe, Takamasa|Harada, Kenichi|Yashima, Kazuo|Nozaka, Kimiyasu|Tanida, Osamu|Kohno, Michimori|Mukoyama, Tomoyuki|Nishimuki, Eiji|Kojo, Haruhiko|Matsura, Tatsuya|Takahashi, Kazuhiko|Osaki, Mitsuhiko|Ito, Hisao|Yodoi,
PMID: 18054426
Journal: Proteomics. 2008 Jan;8(1):45-61.
Title: Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.
Author: Dihal, Ashwin A|van der Woude, Hester|Hendriksen, Peter J M|Charif, Halima|Dekker, Lennard J|Ijsselstijn, Linda|de Boer, Vincent C J|Alink, Gerrit M|Burgers, Peter C|Rietjens, Ivonne M C M|Woutersen, Ruud A|Stierum, Rob H
PMID: 18095365
Journal: Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1144-54.
Title: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.
Author: Peters, Ulrike|Chatterjee, Nilanjan|Hayes, Richard B|Schoen, Robert E|Wang, Yinghui|Chanock, Stephen J|Foster, Charles B
PMID: 18483336
Journal: Br J Nutr. 2011 Aug;106(4):572-82.
Title: The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects.
Author: Hu, Ying|McIntosh, Graeme H|Le Leu, Richard K|Upton, Jane M|Woodman, Richard J|Young, Graeme P
PMID: 21450115
Journal: Genes Chromosomes Cancer. 2012 Jun;51(6):598-605.
Title: Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer.
Author: Haug, Ulrike|Poole, Elizabeth M|Xiao, Liren|Curtin, Karen|Duggan, David|Hsu, Li|Makar, Karen W|Peters, Ulrike|Kulmacz, Richard J|Potter, John D|Koepl, Lisel|Caan, Bette J|Slattery, Martha L|Ulrich, Cornelia M
PMID: 22371331
Journal: Carcinogenesis. 2012 Mar;33(3):620-8.
Title: Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Author: Krehl, Susanne|Loewinger, Maria|Florian, Simone|Kipp, Anna P|Banning, Antje|Wessjohann, Ludger A|Brauer, Martin N|Iori, Renato|Esworthy, Robert S|Chu, Fong-Fong|Brigelius-Flohe, Regina
PMID: 22180572
Journal: Gut. 2013 Jul;62(7):1012-23.
Title: In situ validation of an intestinal stem cell signature in colorectal cancer.
Author: Ziskin, Jennifer L|Dunlap, Debra|Yaylaoglu, Murat|Fodor, Imola K|Forrest, William F|Patel, Rajesh|Ge, Nianfeng|Hutchins, Gordon G|Pine, James K|Quirke, Philip|Koeppen, Hartmut|Jubb, Adrian M
PMID: 22637696
Journal: Biol Trace Elem Res. 2013 Mar;151(3):384-99.
Title: Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats.
Author: Blum, Nicole M|Mueller, Kristin|Lippmann, Doris|Metges, Cornelia C|Linn, Thomas|Pallauf, Josef|Mueller, Andreas S
PMID: 23271678
Journal: PLoS One. 2013 Aug 19;8(8):e72055.
Title: Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.
Author: Muller, Mike F|Florian, Simone|Pommer, Stefanie|Osterhoff, Martin|Esworthy, R Steven|Chu, Fong-Fong|Brigelius-Flohe, Regina|Kipp, Anna P
PMID: 23977205
Journal: Food Funct. 2014 Jun;5(6):1073-81.
Title: Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.
Author: Lippmann, Doris|Lehmann, Carsten|Florian, Simone|Barknowitz, Gitte|Haack, Michael|Mewis, Inga|Wiesner, Melanie|Schreiner, Monika|Glatt, Hansruedi|Brigelius-Flohe, Regina|Kipp, Anna P
PMID: 24714741
Journal: PLoS One. 2014 May 19;9(5):e97818.
Title: Identification and comparison of aberrant key regulatory networks in breast, colon, liver, lung, and stomach cancers through methylome database analysis.
Author: Kim, Byungtak|Kang, Seongeun|Jeong, Gookjoo|Park, Sung-Bin|Kim, Sun Jung
PMID: 24842468
Journal: Proteome Sci. 2014 Jul 11;12:39.
Title: Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.
Author: Rajcevic, Uros|Knol, Jaco C|Piersma, Sander|Bougnaud, Sebastien|Fack, Fred|Sundlisaeter, Eirik|Sondenaa, Karl|Myklebust, Reidar|Pham, Thang V|Niclou, Simone P|Jimenez, Connie R
PMID: 25075203
Journal: Cancer Res. 2014 Nov 15;74(22):6717-30.
Title: GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer.
Author: Emmink, Benjamin L|Laoukili, Jamila|Kipp, Anna P|Koster, Jan|Govaert, Klaas M|Fatrai, Szabolcs|Verheem, Andre|Steller, Ernst J A|Brigelius-Flohe, Regina|Jimenez, Connie R|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 25261240
Journal: Inflamm Bowel Dis. 2015 Sep;21(9):2078-89.
Title: GPx2 Induction Is Mediated Through STAT Transcription Factors During Acute Colitis.
Author: Hiller, Franziska|Besselt, Karolin|Deubel, Stefanie|Brigelius-Flohe, Regina|Kipp, Anna P
PMID: 26115075
Journal: Biomed Res Int. 2015;2015:853573.
Title: Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.
Author: Zmorzynski, Szymon|Swiderska-Kolacz, Grazyna|Koczkodaj, Dorota|Filip, Agata Anna
PMID: 26682223
Journal: PLoS One. 2017 Jan 20;12(1):e0170551.
Title: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.
Author: Soo, Hsien-Chuen|Chung, Felicia Fei-Lei|Lim, Kuan-Hon|Yap, Veronica Alicia|Bradshaw, Tracey D|Hii, Ling-Wei|Tan, Si-Hoey|See, Sze-Jia|Tan, Yuen-Fen|Leong, Chee-Onn|Mai, Chun-Wai
PMID: 28107519
Journal: Oncotarget. 2017 Sep 21;8(49):86296-86311.
Title: Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Author: Jongen, Jennifer M J|van der Waals, Lizet M|Trumpi, Kari|Laoukili, Jamila|Peters, Niek A|Schenning-van Schelven, Susanne J|Govaert, Klaas M|Borel Rinkes, Inne H M|Kranenburg, Onno
PMID: 29156796