Primary Site >> Colorectal Cancer
Gene >> GPX2
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Ref: Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPX-GI. PMID: 9315306 |
Ref: Fluid shear regulates the kinetics and molecular mechanisms of activation-dependent platelet binding to colon carcinoma cells. PMID: 12124268 |
Ref: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. PMID: 15375555 |
Ref: Clinicopathologic correlation of up-regulated genes identified using cDNA microarray and real-time reverse transcription-PCR in human colorectal cancer. PMID: 15734970 Ref: Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon. PMID: 16038882 Ref: Novel sites of cytosolic glutathione peroxidase expression in colon. PMID: 16229841 |
Ref: Aberrant expression of selenoproteins in the progression of colorectal cancer. PMID: 18054426 Ref: Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis. PMID: 18095365 Ref: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. PMID: 18483336 |
Ref: The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects. PMID: 21450115 |
Ref: Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. PMID: 22180572 Ref: Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer. PMID: 22371331 |
Ref: In situ validation of an intestinal stem cell signature in colorectal cancer. PMID: 22637696 Ref: Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats. PMID: 23271678 Ref: Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development. PMID: 23977205 |
Ref: Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently. PMID: 24714741 Ref: Identification and comparison of aberrant key regulatory networks in breast, colon, liver, lung, and stomach cancers through methylome database analysis. PMID: 24842468 Ref: Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture. PMID: 25075203 Ref: GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer. PMID: 25261240 |
Ref: GPx2 Induction Is Mediated Through STAT Transcription Factors During Acute Colitis. PMID: 26115075 Ref: Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors. PMID: 26682223 |
Ref: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. PMID: 28107519 Ref: Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability. PMID: 29156796 |