Primary Site >> Colorectal Cancer

Gene >> GPX1

Journal: Biomed Environ Sci. 1997 Sep;10(2-3):156-62.
Title: Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPX-GI.
Author: Chu, F F|Esworthy, R S|Ho, Y S|Bermeister, M|Swiderek, K|Elliott, R W
PMID: 9315306
Journal: Biochem Biophys Res Commun. 1998 Oct 20;251(2):488-93.
Title: Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells.
Author: Gladyshev, V N|Factor, V M|Housseau, F|Hatfield, D L
PMID: 9792801
Journal: Int J Cancer. 2004 Jul 1;110(4):481-90.
Title: Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice.
Author: Murakami, Akira|Tanaka, Takuji|Lee, Ji-Yoon|Surh, Young-Joon|Kim, Ha Won|Kawabata, Kyuichi|Nakamura, Yoshimasa|Jiwajinda, Suratwadee|Ohigashi, Hajime
PMID: 15122579
Journal: Biochem Pharmacol. 2005 Sep 15;70(6):888-93.
Title: Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon.
Author: Drew, Janice E|Arthur, John R|Farquharson, Andrew J|Russell, Wendy R|Morrice, Philip C|Duthie, Garry G
PMID: 16038882
Journal: FEBS Lett. 2005 Nov 7;579(27):6135-9. Epub 2005 Oct 11.
Title: Novel sites of cytosolic glutathione peroxidase expression in colon.
Author: Drew, Janice E|Farquharson, Andrew J|Arthur, John R|Morrice, Philip C|Duthie, Garry G
PMID: 16229841
Journal: J Nutr. 2005 Dec;135(12 Suppl):3021S-3024S.
Title: Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer.
Author: Hu, Yajun|Benya, Richard V|Carroll, Robert E|Diamond, Alan M
PMID: 16317164
Journal: Cancer Lett. 2008 Feb 8;259(2):218-30.
Title: Aberrant expression of selenoproteins in the progression of colorectal cancer.
Author: Murawaki, Yoshiyuki|Tsuchiya, Hiroyuki|Kanbe, Takamasa|Harada, Kenichi|Yashima, Kazuo|Nozaka, Kimiyasu|Tanida, Osamu|Kohno, Michimori|Mukoyama, Tomoyuki|Nishimuki, Eiji|Kojo, Haruhiko|Matsura, Tatsuya|Takahashi, Kazuhiko|Osaki, Mitsuhiko|Ito, Hisao|Yodoi,
PMID: 18054426
Journal: Antioxid Redox Signal. 2008 Sep;10(9):1491-500.
Title: GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells.
Author: Banning, Antje|Florian, Simone|Deubel, Stefanie|Thalmann, Sophie|Muller-Schmehl, Katrin|Jacobasch, Gisela|Brigelius-Flohe, Regina
PMID: 18479189
Journal: Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1144-54.
Title: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.
Author: Peters, Ulrike|Chatterjee, Nilanjan|Hayes, Richard B|Schoen, Robert E|Wang, Yinghui|Chanock, Stephen J|Foster, Charles B
PMID: 18483336
Journal: Mutat Res. 2009 May 12;664(1-2):13-9.
Title: GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer.
Author: Hansen, Rikke Dalgaard|Krath, Britta Naimi|Frederiksen, Kirsten|Tjonneland, Anne|Overvad, Kim|Roswall, Nina|Loft, Steffen|Dragsted, Lars Ove|Vogel, Ulla|Raaschou-Nielsen, Ole
PMID: 19428376
Journal: Br J Nutr. 2010 Jul;104(1):17-23.
Title: Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon.
Author: Hu, Ying|McIntosh, Graeme H|Le Leu, Richard K|Young, Graeme P
PMID: 20346189
Journal: Toxicol Lett. 2010 Dec 15;199(3):277-87.
Title: Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.
Author: Qi, Xu-Feng|Kim, Dong-Heui|Yoon, Yang-Suk|Kim, Soo-Ki|Cai, Dong-Qing|Teng, Yung-Chien|Shim, Kwang-Yong|Lee, Kyu-Jae
PMID: 20883752
Journal: Carcinogenesis. 2010 Jun;31(6):1074-9.
Title: Genetic variants in selenoprotein genes increase risk of colorectal cancer.
Author: Meplan, Catherine|Hughes, David J|Pardini, Barbara|Naccarati, Alessio|Soucek, Pavel|Vodickova, Ludmila|Hlavata, Ivona|Vrana, David|Vodicka, Pavel|Hesketh, John E
PMID: 20378690
Journal: Br J Nutr. 2011 Aug;106(4):572-82.
Title: The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects.
Author: Hu, Ying|McIntosh, Graeme H|Le Leu, Richard K|Upton, Jane M|Woodman, Richard J|Young, Graeme P
PMID: 21450115
Journal: Cancer Epidemiol Biomarkers Prev. 2011 Sep;20(9):1822-30.
Title: Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis.
Author: Takata, Yumie|Kristal, Alan R|King, Irena B|Song, Xiaoling|Diamond, Alan M|Foster, Charles B|Hutter, Carolyn M|Hsu, Li|Duggan, David J|Langer, Robert D|Petrovitch, Helen|Shikany, James M|Vaughan, Thomas L|Lampe, Johanna W|Prentice, Ross L|Peters, Ulrike
PMID: 21765007
Journal: Lab Anim Res. 2011 Mar;27(1):9-18.
Title: Effects of selenium on colon carcinogenesis induced by azoxymethane and dextran sodium sulfate in mouse model with high-iron diet.
Author: Kim, Jun-Hyeong|Hue, Jin-Joo|Kang, Bong Su|Park, Hyunji|Nam, Sang Yoon|Yun, Young Won|Kim, Jong-Soo|Lee, Beom Jun
PMID: 21826154
Journal: Anticancer Res. 2011 Sep;31(9):2693-8.
Title: Expression of selenium-containing proteins in human colon carcinoma tissue.
Author: Yagublu, V|Arthur, J R|Babayeva, S N|Nicol, F|Post, S|Keese, M
PMID: 21868509
Journal: Genes Cancer. 2011 Sep;2(9):910-3.
Title: Loss of heterozygosity at the glutathione peroxidase 1 locus is not an early event in colon carcinogenesis.
Author: Goldberg, Marci|Alberts, David S|Buckmeier, Julie A|Prasad, Anil R|Krouse, Robert S|Diamond, Alan M
PMID: 22593803
Journal: Carcinogenesis. 2012 Mar;33(3):620-8.
Title: Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Author: Krehl, Susanne|Loewinger, Maria|Florian, Simone|Kipp, Anna P|Banning, Antje|Wessjohann, Ludger A|Brauer, Martin N|Iori, Renato|Esworthy, Robert S|Chu, Fong-Fong|Brigelius-Flohe, Regina
PMID: 22180572
Journal: Genes Chromosomes Cancer. 2012 Jun;51(6):598-605.
Title: Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer.
Author: Haug, Ulrike|Poole, Elizabeth M|Xiao, Liren|Curtin, Karen|Duggan, David|Hsu, Li|Makar, Karen W|Peters, Ulrike|Kulmacz, Richard J|Potter, John D|Koepl, Lisel|Caan, Bette J|Slattery, Martha L|Ulrich, Cornelia M
PMID: 22371331
Journal: Mutagenesis. 2012 Mar;27(2):177-86.
Title: The influence of selenium and selenoprotein gene variants on colorectal cancer risk.
Author: Meplan, Catherine|Hesketh, John
PMID: 22294765
Journal: Int J Mol Med. 2012 May;29(5):906-12.
Title: Transforming growth factor-beta1 induces glutathione peroxidase-1 and protects from H2O2-induced cell death in colon cancer cells via the Smad2/ERK1/2/HIF-1alpha pathway.
Author: Huang, Ying|Fang, Wenfeng|Wang, Yulei|Yang, Wancai|Xiong, Bin
PMID: 22307228
Journal: Biol Trace Elem Res. 2013 Mar;151(3):384-99.
Title: Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats.
Author: Blum, Nicole M|Mueller, Kristin|Lippmann, Doris|Metges, Cornelia C|Linn, Thomas|Pallauf, Josef|Mueller, Andreas S
PMID: 23271678
Journal: Cancer Treat Res. 2014;159:145-66.
Title: Selenium and cancer: a story that should not be forgotten-insights from genomics.
Author: Meplan, Catherine|Hesketh, John
PMID: 24114479
Journal: Anticancer Res. 2015 Jan;35(1):255-9.
Title: Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer.
Author: Nalkiran, Ihsan|Turan, Saime|Arikan, Soykan|Kahraman, Ozlem Timirci|Acar, Leyla|Yaylim, Ilhan|Ergen, Arzu
PMID: 25550558
Journal: Free Radic Biol Med. 2015 Aug;85:45-55.
Title: Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer.
Author: Miar, Ana|Hevia, David|Munoz-Cimadevilla, Henar|Astudillo, Aurora|Velasco, Julio|Sainz, Rosa M|Mayo, Juan C
PMID: 25866291
Journal: Biomed Res Int. 2015;2015:853573.
Title: Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.
Author: Zmorzynski, Szymon|Swiderska-Kolacz, Grazyna|Koczkodaj, Dorota|Filip, Agata Anna
PMID: 26682223
Journal: Crit Rev Oncol Hematol. 2016 Nov;107:72-81.
Title: Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer.
Author: Baroudi, Olfa|Benammar-Elgaaied, Amel
PMID: 27823653
Journal: Biomol Ther (Seoul). 2016 May 1;24(3):320-7.
Title: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.
Author: Kang, Ji In|Hong, Ji-Young|Choi, Jae Sue|Lee, Sang Kook
PMID: 27098859
Journal: Mol Carcinog. 2017 May;56(5):1461-1471.
Title: Chemopreventive potential of in vitro fermented nuts in LT97 colon adenoma and primary epithelial colon cells.
Author: Schlormann, Wiebke|Lamberty, Julia|Lorkowski, Stefan|Ludwig, Diana|Mothes, Henning|Saupe, Christian|Glei, Michael
PMID: 27996158
Journal: Cancer Biol Ther. 2017 Apr 3;18(4):257-267.
Title: Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer.
Author: Saxena, Arpit|Fayad, Raja|Kaur, Kamaljeet|Truman, Samantha|Greer, Julian|Carson, James A|Chanda, Anindya
PMID: 28045589
Journal: Int J Mol Sci. 2017 Apr 17;18(4). pii: ijms18040851.
Title: Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.
Author: Noma, Nobuharu|Fujii, Gen|Miyamoto, Shingo|Komiya, Masami|Nakanishi, Ruri|Shimura, Misato|Tanuma, Sei-Ichi|Mutoh, Michihiro
PMID: 28420165
Journal: Elife. 2017 Jun 5;6.
Title: Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3.
Author: Chaudhary, Ritu|Gryder, Berkley|Woods, Wendy S|Subramanian, Murugan|Jones, Matthew F|Li, Xiao Ling|Jenkins, Lisa M|Shabalina, Svetlana A|Mo, Min|Dasso, Mary|Yang, Yuan|Wakefield, Lalage M|Zhu, Yuelin|Frier, Susan M|Moriarity, Branden S|Prasanth, Kannangan
PMID: 28580901
Journal: Nutr Res. 2017 Nov;47:72-80.
Title: In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells.
Author: Schlormann, W|Lamberty, J|Ludwig, D|Lorkowski, S|Glei, M
PMID: 29241580
Journal: Nutrients. 2017 Dec 18;9(12). pii: nu9121368.
Title: Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis.
Author: Glei, Michael|Ludwig, Diana|Lamberty, Julia|Fischer, Sonja|Lorkowski, Stefan|Schlormann, Wiebke
PMID: 29258268
Journal: Int J Food Sci Nutr. 2018 Feb;69(1):52-63.
Title: Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells.
Author: Schlormann, Wiebke|Fischer, Sonja|Saupe, Christian|Dinc, Tulin|Lorkowski, Stefan|Glei, Michael
PMID: 28583046
Journal: Anticancer Res. 2018 Jan;38(1):83-93.
Title: Chemopreventive Potential of In Vitro Fermented Raw and Roasted Hazelnuts in LT97 Colon Adenoma Cells.
Author: Glei, Michael|Fischer, Sonja|Lamberty, Julia|Ludwig, Diana|Lorkowski, Stefan|Schlormann, Wiebke
PMID: 29277760