Primary Site >> Colorectal Cancer

Gene >> GPX1

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Ref: Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPX-GI.
PMID: 9315306
Ref: Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells.
PMID: 9792801
Ref: Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice.
PMID: 15122579
Ref: Salicylic acid modulates oxidative stress and glutathione peroxidase activity in the rat colon.
PMID: 16038882
Ref: Novel sites of cytosolic glutathione peroxidase expression in colon.
PMID: 16229841
Ref: Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer.
PMID: 16317164
Ref: Aberrant expression of selenoproteins in the progression of colorectal cancer.
PMID: 18054426
Ref: GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells.
PMID: 18479189
Ref: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.
PMID: 18483336
Ref: GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer.
PMID: 19428376
Ref: Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon.
PMID: 20346189
Ref: Genetic variants in selenoprotein genes increase risk of colorectal cancer.
PMID: 20378690
Ref: Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.
PMID: 20883752
Ref: The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects.
PMID: 21450115
Ref: Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis.
PMID: 21765007
Ref: Effects of selenium on colon carcinogenesis induced by azoxymethane and dextran sodium sulfate in mouse model with high-iron diet.
PMID: 21826154
Ref: Expression of selenium-containing proteins in human colon carcinoma tissue.
PMID: 21868509
Ref: Loss of heterozygosity at the glutathione peroxidase 1 locus is not an early event in colon carcinogenesis.
PMID: 22593803
Ref: Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
PMID: 22180572
Ref: The influence of selenium and selenoprotein gene variants on colorectal cancer risk.
PMID: 22294765
Ref: Transforming growth factor-beta1 induces glutathione peroxidase-1 and protects from H2O2-induced cell death in colon cancer cells via the Smad2/ERK1/2/HIF-1alpha pathway.
PMID: 22307228
Ref: Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer.
PMID: 22371331
Ref: Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats.
PMID: 23271678
Ref: Selenium and cancer: a story that should not be forgotten-insights from genomics.
PMID: 24114479
Ref: Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer.
PMID: 25550558
Ref: Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer.
PMID: 25866291
Ref: Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.
PMID: 26682223
Ref: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.
PMID: 27098859
Ref: Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer.
PMID: 27823653
Ref: Chemopreventive potential of in vitro fermented nuts in LT97 colon adenoma and primary epithelial colon cells.
PMID: 27996158
Ref: Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer.
PMID: 28045589
Ref: Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice.
PMID: 28420165
Ref: Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3.
PMID: 28580901
Ref: In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells.
PMID: 29241580
Ref: Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis.
PMID: 29258268
Ref: Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells.
PMID: 28583046
Ref: Chemopreventive Potential of In Vitro Fermented Raw and Roasted Hazelnuts in LT97 Colon Adenoma Cells.
PMID: 29277760