Primary Site >> Colorectal Cancer

Gene >> GLI2

Journal: Cytogenet Cell Genet. 2001;92(3-4):225-30.
Title: cDNA cloning, chromosome assignment, and genomic structure of a human gene encoding a novel member of the RBM family.
Author: Stover, C|Gradl, G|Jentsch, I|Speicher, M R|Wieser, R|Schwaeble, W
PMID: 11435693
Journal: Int J Oncol. 2005 Feb;26(2):545-9.
Title: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 15645142
Journal: Oncol Rep. 2005 Oct;14(4):1087-90.
Title: Comparative genomics on Sonic hedgehog orthologs.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16142377
Journal: Int J Cancer. 2007 Dec 15;121(12):2622-7.
Title: Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
Author: Chatel, Guillaume|Ganeff, Corine|Boussif, Naima|Delacroix, Laurence|Briquet, Alexandra|Nolens, Gregory|Winkler, Rosita
PMID: 17683069
Journal: Virchows Arch. 2009 Apr;454(4):369-79.
Title: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
Author: Alinger, Beate|Kiesslich, Tobias|Datz, Christian|Aberger, Fritz|Strasser, Felix|Berr, Frieder|Dietze, Otto|Kaserer, Klaus|Hauser-Kronberger, Cornelia
PMID: 19280222
Journal: Oncogene. 2009 Nov 5;28(44):3892-902.
Title: Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3.
Author: Kaler, P|Augenlicht, L|Klampfer, L
PMID: 19701245
Journal: Cancer Microenviron. 2009 Sep 25;2(1):69-80.
Title: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta.
Author: Kaler, Pawan|Godasi, Bramara N|Augenlicht, Leonard|Klampfer, Lidija
PMID: 19779850
Journal: PLoS One. 2010 Oct 1;5(10). pii: e13054.
Title: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Author: Shi, Ting|Mazumdar, Tapati|Devecchio, Jennifer|Duan, Zhong-Hui|Agyeman, Akwasi|Aziz, Mohammad|Houghton, Janet A
PMID: 20957031
Journal: Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A
PMID: 21135115
Journal: Cancer Res. 2011 Sep 1;71(17):5904-14.
Title: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Author: Mazumdar, Tapati|Devecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A
PMID: 21747117
Journal: Oncotarget. 2011 Aug;2(8):638-45.
Title: The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A
PMID: 21860067
Journal: Oncotarget. 2012 Aug;3(8):854-68.
Title: Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
Author: Agyeman, Akwasi|Mazumdar, Tapati|Houghton, Janet A
PMID: 23097684
Journal: PLoS One. 2013 Jul 23;8(7):e69132.
Title: Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer.
Author: Chowdhury, Saikat|Pradhan, Rachana N|Sarkar, Ram Rup
PMID: 23935937
Journal: PLoS One. 2013 Sep 25;8(9):e75253.
Title: Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells.
Author: Mazumdar, Tapati|Sandhu, Ranjodh|Qadan, Maha|DeVecchio, Jennifer|Magloire, Victoria|Agyeman, Akwasi|Li, Bibo|Houghton, Janet A
PMID: 24086482
Journal: Ann Clin Lab Sci. 2014 Winter;44(1):99-103.
Title: Heterotopic ossification in metastatic colorectal carcinoma: case report with morphoproteomic insights into the histogenesis.
Author: Huang, Richard Sheng Poe|Brown, Robert E|Buryanek, Jamie
PMID: 24695482
Journal: Oncotarget. 2014 Jun 30;5(12):4492-503.
Title: Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
Author: Agyeman, Akwasi|Jha, Babal K|Mazumdar, Tapati|Houghton, Janet A
PMID: 24962990
Journal: Onco Targets Ther. 2015 Apr 17;8:877-83.
Title: Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002.
Author: Cai, Xinyi|Yu, Kun|Zhang, Lijuan|Li, Yunfeng|Li, Qiang|Yang, Zhibin|Shen, Tao|Duan, Lincan|Xiong, Wei|Wang, Weiya
PMID: 25945059
Journal: J Mol Cell Biol. 2016 Apr;8(2):157-73.
Title: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.
Author: Singovski, Grigori|Bernal, Carolina|Kuciak, Monika|Siegl-Cachedenier, Irene|Conod, Arwen|Ruiz I Altaba, Ariel
PMID: 26031752
Journal: Cell Death Dis. 2016 Dec 29;7(12):e2569.
Title: Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer.
Author: Zhi, Xiaofei|Tao, Jinqiu|Zhang, Lei|Tao, Ran|Ma, Lilin|Qin, Jun
PMID: 28032859
Journal: Cell Biosci. 2017 Apr 13;7:17.
Title: The role of GLI1 for 5-Fu resistance in colorectal cancer.
Author: Zhang, Lining|Song, Ruolan|Gu, Dongsheng|Zhang, Xiaoli|Yu, Beiqin|Liu, Bingya|Xie, Jingwu
PMID: 28413604
Journal: Front Pharmacol. 2018 Feb 2;8:956.
Title: SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.
Author: Magistri, Paolo|Battistelli, Cecilia|Strippoli, Raffaele|Petrucciani, Niccolo|Pellinen, Teijo|Rossi, Lucia|Mangogna, Livia|Aurello, Paolo|D'Angelo, Francesco|Tripodi, Marco|Ramacciato, Giovanni|Nigri, Giuseppe
PMID: 29456503
Journal: Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5990-E5999.
Title: Hypoxic tumor microenvironment activates GLI2 via HIF-1alpha and TGF-beta2 to promote chemoresistance in colorectal cancer.
Author: Tang, Yen-An|Chen, Yu-Feng|Bao, Yi|Mahara, Sylvia|Yatim, Siti Maryam J M|Oguz, Gokce|Lee, Puay Leng|Feng, Min|Cai, Yu|Tan, Ern Yu|Fong, Sau Shung|Yang, Zi-Huan|Lan, Ping|Wu, Xiao-Jian|Yu, Qiang
PMID: 29891662