Primary Site >> Colorectal Cancer
Gene >> GLI2
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Ref: cDNA cloning, chromosome assignment, and genomic structure of a human gene encoding a novel member of the RBM family. PMID: 11435693 |
Ref: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico. PMID: 15645142 Ref: Comparative genomics on Sonic hedgehog orthologs. PMID: 16142377 |
Ref: Hedgehog signaling pathway is inactive in colorectal cancer cell lines. PMID: 17683069 |
Ref: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation. PMID: 19280222 Ref: Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3. PMID: 19701245 Ref: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta. PMID: 19779850 |
Ref: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. PMID: 20957031 |
Ref: Hedgehog signaling drives cellular survival in human colon carcinoma cells. PMID: 21135115 Ref: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. PMID: 21747117 Ref: The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer. PMID: 21860067 |
Ref: Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer. PMID: 23097684 |
Ref: Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer. PMID: 23935937 Ref: Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells. PMID: 24086482 |
Ref: Heterotopic ossification in metastatic colorectal carcinoma: case report with morphoproteomic insights into the histogenesis. PMID: 24695482 Ref: Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding. PMID: 24962990 |
Ref: Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002. PMID: 25945059 |
Ref: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases. PMID: 26031752 Ref: Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer. PMID: 28032859 |
Ref: The role of GLI1 for 5-Fu resistance in colorectal cancer. PMID: 28413604 Ref: SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer. PMID: 29456503 |
Ref: Hypoxic tumor microenvironment activates GLI2 via HIF-1alpha and TGF-beta2 to promote chemoresistance in colorectal cancer. PMID: 29891662 |