Primary Site >> Colorectal Cancer

Gene >> GLI1

Journal: Cancer Res. 2000 Nov 15;60(22):6488-95.
Title: Increase of GKLF messenger RNA and protein expression during progression of breast cancer.
Author: Foster, K W|Frost, A R|McKie-Bell, P|Lin, C Y|Engler, J A|Grizzle, W E|Ruppert, J M
PMID: 11103818
Journal: Int J Cancer. 2004 Jul 20;110(6):831-7.
Title: Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment.
Author: Qualtrough, David|Buda, Andrea|Gaffield, William|Williams, Ann C|Paraskeva, Christos
PMID: 15170664
Journal: Int J Oncol. 2005 Feb;26(2):545-9.
Title: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 15645142
Journal: Oncol Rep. 2005 Oct;14(4):1087-90.
Title: Comparative genomics on Sonic hedgehog orthologs.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16142377
Journal: Gut. 2006 Jul;55(7):991-9. Epub 2005 Nov 18.
Title: Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation.
Author: Akiyoshi, T|Nakamura, M|Koga, K|Nakashima, H|Yao, T|Tsuneyoshi, M|Tanaka, M|Katano, M
PMID: 16299030
Journal: Surgery. 2006 May;139(5):665-70.
Title: Sonic Hedgehog-dependent proliferation in a series of patients with colorectal cancer.
Author: Douard, Richard|Moutereau, Stephane|Pernet, Pascal|Chimingqi, Mihelaiti|Allory, Yves|Manivet, Philippe|Conti, Marc|Vaubourdolle, Michel|Cugnenc, Paul-Henri|Loric, Sylvain
PMID: 16701100
Journal: World J Gastroenterol. 2007 Mar 21;13(11):1659-65.
Title: Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas.
Author: Bian, Yue-Hong|Huang, Shu-Hong|Yang, Ling|Ma, Xiao-Li|Xie, Jing-Wu|Zhang, Hong-Wei
PMID: 17461467
Journal: Int J Cancer. 2007 Dec 15;121(12):2622-7.
Title: Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
Author: Chatel, Guillaume|Ganeff, Corine|Boussif, Naima|Delacroix, Laurence|Briquet, Alexandra|Nolens, Gregory|Winkler, Rosita
PMID: 17683069
Journal: Virchows Arch. 2009 Apr;454(4):369-79.
Title: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
Author: Alinger, Beate|Kiesslich, Tobias|Datz, Christian|Aberger, Fritz|Strasser, Felix|Berr, Frieder|Dietze, Otto|Kaserer, Klaus|Hauser-Kronberger, Cornelia
PMID: 19280222
Journal: EMBO Mol Med. 2009 Sep;1(6-7):338-51.
Title: Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion.
Author: Varnat, Frederic|Duquet, Arnaud|Malerba, Monica|Zbinden, Marie|Mas, Christophe|Gervaz, Pascal|Ruiz i Altaba, Ariel
PMID: 20049737
Journal: Cancer Res. 2009 Nov 15;69(22):8572-8.
Title: Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA.
Author: Noubissi, Felicite K|Goswami, Srikanta|Sanek, Nicholas A|Kawakami, Kazuyuki|Minamoto, Toshinari|Moser, Amy|Grinblat, Yevgenya|Spiegelman, Vladimir S
PMID: 19887615
Journal: Mol Cell Biochem. 2010 Apr;337(1-2):185-92.
Title: Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters.
Author: Fu, Xiangsheng|Deng, Hong|Zhao, Luping|Li, Jing|Zhou, Yongbai|Zhang, Yali
PMID: 19856079
Journal: Mech Dev. 2010 Jan-Feb;127(1-2):73-81.
Title: Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling.
Author: Varnat, Frederic|Zacchetti, Giovanna|Ruiz i Altaba, Ariel
PMID: 19861162
Journal: PLoS One. 2010 Oct 1;5(10). pii: e13054.
Title: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Author: Shi, Ting|Mazumdar, Tapati|Devecchio, Jennifer|Duan, Zhong-Hui|Agyeman, Akwasi|Aziz, Mohammad|Houghton, Janet A
PMID: 20957031
Journal: Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1511-8.
Title: Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
Author: Wu, Jian-Ye|Xu, Xuan-Fu|Xu, Ling|Niu, Pei-Qin|Wang, Feng|Hu, Guo-Yong|Wang, Xing-Peng|Guo, Chuan-Yong
PMID: 21940310
Journal: Sci Signal. 2011 Nov 22;4(200):pt9.
Title: Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Author: Ruiz i Altaba, Ariel
PMID: 22114144
Journal: Oncotarget. 2011 Aug;2(8):638-45.
Title: The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A
PMID: 21860067
Journal: Mol Med Rep. 2011 Sep-Oct;4(5):873-7.
Title: Differential expression profiles of the Hedgehog signaling pathway between microsatellite-stable and microsatellite-unstable colorectal cancers.
Author: Hu, Xuguang|Lai, Daili|Chen, Wei|Zi, Shuming|Li, Jinming|Du, Peng|Wang, Zhongchuan|Huang, Shiyong|Long, Cui
PMID: 21725600
Journal: Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A
PMID: 21135115
Journal: Clin Cancer Res. 2011 Jul 15;17(14):4682-92.
Title: Pharmacokinetic-pharmacodynamic analysis of vismodegib in preclinical models of mutational and ligand-dependent Hedgehog pathway activation.
Author: Wong, Harvey|Alicke, Bruno|West, Kristina A|Pacheco, Patricia|La, Hank|Januario, Tom|Yauch, Robert L|de Sauvage, Frederic J|Gould, Stephen E
PMID: 21610148
Journal: Cancer Res. 2011 Sep 1;71(17):5904-14.
Title: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Author: Mazumdar, Tapati|Devecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A
PMID: 21747117
Journal: Oncotarget. 2012 Aug;3(8):854-68.
Title: Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
Author: Agyeman, Akwasi|Mazumdar, Tapati|Houghton, Janet A
PMID: 23097684
Journal: Asian Pac J Cancer Prev. 2012;13(8):4001-5.
Title: Expression of smoothened protein in colon cancer and its prognostic value for postoperative liver metastasis.
Author: Ding, Yin-Lu|Wang, Qi-San|Zhao, Wei-Min|Xiang, Lei
PMID: 23098507
Journal: PLoS One. 2012;7(9):e45332.
Title: Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
Author: Yoshimoto, Agnes N|Bernardazzi, Claudio|Carneiro, Antonio Jose V|Elia, Celeste C S|Martinusso, Cesonia A|Ventura, Grasiella M|Castelo-Branco, Morgana T L|de Souza, Heitor S P
PMID: 23028941
Journal: Asian Pac J Cancer Prev. 2012;13(5):2319-24.
Title: Expression and clinical significance of hedgehog signaling pathway related components in colorectal cancer.
Author: Wang, Hong|Li, Yu-Yuan|Wu, Ying-Ying|Nie, Yu-Qiang
PMID: 22901214
Journal: Mol Cancer Res. 2012 Sep;10(9):1147-57.
Title: Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.
Author: Hwang, Rosa F|Moore, Todd T|Hattersley, Maureen Mertens|Scarpitti, Meghan|Yang, Bin|Devereaux, Erik|Ramachandran, Vijaya|Arumugam, Thiruvengadam|Ji, Baoan|Logsdon, Craig D|Brown, Jeffrey L|Godin, Robert
PMID: 22859707
Journal: Int J Med Sci. 2012;9(5):334-8.
Title: Expression of glioma-associated oncogene homolog 1 is associated with invasion and postoperative liver metastasis in colon cancer.
Author: Ding, Yin-lu|Zhou, Yong|Xiang, Lei|Ji, Zhi-peng|Luo, Zhou-hong
PMID: 22745574
Journal: Carcinogenesis. 2012 Jun;33(6):1158-68.
Title: Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
Author: Wang, Tz-Ping|Hsu, Shu-Han|Feng, Hsin-Chun|Huang, Rwei-Fen S
PMID: 22461522
Journal: Exp Cell Res. 2012 Mar 10;318(5):539-49.
Title: Abrogation of Gli3 expression suppresses the growth of colon cancer cells via activation of p53.
Author: Kang, Han Na|Oh, Sang Cheul|Kim, Jun Suk|Yoo, Young A
PMID: 22227409
Journal: Med Oncol. 2012 Jun;29(2):1010-6.
Title: Prognostic value of hedgehog signaling pathway in patients with colon cancer.
Author: Xu, Meihua|Li, Xinhua|Liu, Ting|Leng, Aimin|Zhang, Guiying
PMID: 21424326
Journal: Int J Cancer. 2013 Jan 15;132(2):E18-25.
Title: Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci.
Author: Peng, Liang|Hu, Jingjing|Li, Shujun|Wang, Zhongqiu|Xia, Bingqing|Jiang, Bo|Li, Bingsheng|Zhang, Yu|Wang, Jing|Wang, Xinying
PMID: 22945423
Journal: Am Surg. 2013 Feb;79(2):198-204.
Title: Expression of GLI1 correlates with expression of lymphangiogenesis proteins, vascular endothelial growth factor C and vascular endothelial growth factor receptor 3, in colorectal cancer.
Author: Hong, Kwang Dae|Lee, Youngseok|Kim, Baek-Hui|Lee, Sun Il|Moon, Hong Young
PMID: 23336661
Journal: J Dig Dis. 2013 Aug;14(8):417-24.
Title: Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli.
Author: Wang, Zhong Chuan|Gao, Jun|Zi, Shu Ming|Yang, Ming|Du, Peng|Cui, Long
PMID: 23551431
Journal: PLoS One. 2013 Jul 23;8(7):e69132.
Title: Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer.
Author: Chowdhury, Saikat|Pradhan, Rachana N|Sarkar, Ram Rup
PMID: 23935937
Journal: PLoS One. 2013 Sep 25;8(9):e75253.
Title: Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells.
Author: Mazumdar, Tapati|Sandhu, Ranjodh|Qadan, Maha|DeVecchio, Jennifer|Magloire, Victoria|Agyeman, Akwasi|Li, Bibo|Houghton, Janet A
PMID: 24086482
Journal: Oncotarget. 2013 Dec;4(12):2208-11.
Title: A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis.
Author: Chung, Jon H|Bunz, Fred
PMID: 24368541
Journal: PLoS One. 2014 Nov 11;9(11):e112700.
Title: p, p'-Dichlorodiphenyldichloroethylene induces colorectal adenocarcinoma cell proliferation through oxidative stress.
Author: Song, Li|Liu, Jianxin|Jin, Xiaoting|Li, Zhuoyu|Zhao, Meirong|Liu, Weiping
PMID: 25386960
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1687-97.
Title: A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Author: Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin
PMID: 24470513
Journal: Oncol Lett. 2014 Nov;8(5):2203-2208.
Title: Hedgehog-glioma-associated oncogene homolog-1 signaling in colon cancer cells and its role in the celecoxib-mediated anti-cancer effect.
Author: Wang, Hongtao|Ke, Fei|Zheng, Jie
PMID: 25295109
Journal: Pharmacogenomics J. 2014 Apr;14(2):142-50.
Title: Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence.
Author: Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J
PMID: 23817222
Journal: Oncotarget. 2014 Jun 30;5(12):4492-503.
Title: Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
Author: Agyeman, Akwasi|Jha, Babal K|Mazumdar, Tapati|Houghton, Janet A
PMID: 24962990
Journal: Tumour Biol. 2015 Mar;36(3):2013-21.
Title: beta1 integrin mediates colorectal cancer cell proliferation and migration through regulation of the Hedgehog pathway.
Author: Song, Jia|Zhang, Jixiang|Wang, Jing|Wang, Jun|Guo, Xufeng|Dong, Weiguo
PMID: 25387809
Journal: Clin Cancer Res. 2015 Mar 1;21(5):1002-9.
Title: Phase I dose-escalation trial of the oral investigational Hedgehog signaling pathway inhibitor TAK-441 in patients with advanced solid tumors.
Author: Goldman, Jonathan|Eckhardt, S Gail|Borad, Mitesh J|Curtis, Kelly K|Hidalgo, Manuel|Calvo, Emiliano|Ryan, David P|Wirth, Lori J|Parikh, Asit|Partyka, James|Faessel, Helene|Gangolli, Esha|Stewart, Sally|Rosen, Lee S|Bowles, Daniel W
PMID: 25501576
Journal: Cancer Biol Ther. 2015;16(1):1-7.
Title: Crosstalk between Wnt/beta-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy.
Author: Song, Li|Li, Zhuo-Yu|Liu, Wei-Ping|Zhao, Mei-Rong
PMID: 25692617
Journal: Onco Targets Ther. 2015 Apr 17;8:877-83.
Title: Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002.
Author: Cai, Xinyi|Yu, Kun|Zhang, Lijuan|Li, Yunfeng|Li, Qiang|Yang, Zhibin|Shen, Tao|Duan, Lincan|Xiong, Wei|Wang, Weiya
PMID: 25945059
Journal: Biochim Biophys Acta. 2015 Dec;1852(12):2574-84.
Title: GSK3beta and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3beta downregulates the signaling pathway and reduces cell proliferation.
Author: Trnski, Diana|Sabol, Maja|Gojevic, Ante|Martinic, Marina|Ozretic, Petar|Musani, Vesna|Ramic, Snjezana|Levanat, Sonja
PMID: 26385428
Journal: Int J Clin Exp Pathol. 2015 Sep 1;8(9):10092-101. eCollection 2015.
Title: Inhibition of SALL4 suppresses carcinogenesis of colorectal cancer via regulating Gli1 expression.
Author: Cheng, Ji|Deng, Rui|Wu, Chuanqing|Zhang, Peng|Wu, Ke|Shi, Liang|Liu, Xinghua|Bai, Jie|Deng, Meizhou|Gao, Jinbo|Shuai, Xiaoming|Wang, Guobin|Tao, Kaixiong
PMID: 26617716
Journal: Int J Clin Exp Med. 2015 Nov 15;8(11):21379-85. eCollection 2015.
Title: Dysregulation of hedgehog signaling pathway related components in the evolution of colonic carcinogenesis.
Author: Zhang, Xu|Zhang, Sa-Sa|Wei, Gui-Jun|Deng, Zhong-Min|Hu, Yi
PMID: 26885080
Journal: Heliyon. 2016 May 11;2(5):e00109.
Title: Neoexpression of a functional primary cilium in colorectal cancer cells.
Author: Senicourt, Blanche|Boudjadi, Salah|Carrier, Julie C|Beaulieu, Jean-Francois
PMID: 27441280
Journal: Iran J Basic Med Sci. 2016 Nov;19(11):1171-1176.
Title: The hedgehog/Gli-1 signaling pathways is involved in the inhibitory effect of resveratrol on human colorectal cancer HCT116 cells.
Author: Du, Zhou|Zhou, Feng|Jia, Zengrong|Zheng, Beishi|Han, Shaoliang|Cheng, Jun|Zhu, Guanbao|Huang, Ping
PMID: 27917272
Journal: Oncotarget. 2016 Dec 27;7(52):86816-86828.
Title: Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer.
Author: Wang, Rong|Wei, Jinlai|Zhang, Shouru|Wu, Xingye|Guo, Jinbao|Liu, Maoxi|Du, Kunli|Xu, Jun|Peng, Linglong|Lv, Zhenbing|You, Wenxian|Xiong, Yongfu|Fu, Zhongxue
PMID: 27894099
Journal: Oncotarget. 2016 Dec 6;7(49):80190-80207.
Title: Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.
Author: Zhang, Ruowen|Wu, Jiahui|Ferrandon, Sylvain|Glowacki, Katie J|Houghton, Janet A
PMID: 27863397
Journal: Oncotarget. 2016 Dec 27;7(52):86134-86147.
Title: Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling.
Author: Zhang, Chuan|Wang, Yong|Feng, YiFei|Zhang, Yue|Ji, Bing|Wang, Sen|Sun, Ye|Zhu, Chunyan|Zhang, Dongsheng|Sun, Yueming
PMID: 27863385
Journal: Oncol Res. 2016;24(3):137-44.
Title: Knockdown of PFTAIRE Protein Kinase 1 (PFTK1) Inhibits Proliferation, Invasion, and EMT in Colon Cancer Cells.
Author: Zhu, Jiankang|Liu, Chongzhong|Liu, Fengyue|Wang, Yadong|Zhu, Min
PMID: 27458094
Journal: Mol Pharmacol. 2016 Jun;89(6):606-17.
Title: Inhibition of GLI1 Expression by Targeting the CRD-BP-GLI1 mRNA Interaction Using a Specific Oligonucleotide.
Author: Mehmood, Kashif|Akhtar, Daud|Mackedenski, Sebastian|Wang, Chuyi|Lee, Chow H
PMID: 27036131
Journal: Mol Pharmacol. 2016 Feb;89(2):226-32.
Title: Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.
Author: Li, Bin|Giambelli, Camilla|Tang, Bo|Winterbottom, Emily|Long, Jun|Jin, Ke|Wang, Zhiqiang|Fei, Dennis Liang|Nguyen, Dao M|Athar, Mohammad|Wang, Baolin|Subbarayan, Pochi R|Wang, Lily|Rai, Priyamvada|Ardalan, Bach|Capobianco, Anthony J|Robbins, David J
PMID: 26573582
Journal: J Mol Cell Biol. 2016 Apr;8(2):157-73.
Title: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.
Author: Singovski, Grigori|Bernal, Carolina|Kuciak, Monika|Siegl-Cachedenier, Irene|Conod, Arwen|Ruiz I Altaba, Ariel
PMID: 26031752
Journal: J Exp Clin Cancer Res. 2017 Feb 2;36(1):23.
Title: Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.
Author: Wang, DeJie|Hu, Guohui|Du, Ying|Zhang, Cheng|Lu, Quqin|Lv, Nonghua|Luo, Shiwen
PMID: 28148279
Journal: Front Pharmacol. 2018 Feb 2;8:956.
Title: SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.
Author: Magistri, Paolo|Battistelli, Cecilia|Strippoli, Raffaele|Petrucciani, Niccolo|Pellinen, Teijo|Rossi, Lucia|Mangogna, Livia|Aurello, Paolo|D'Angelo, Francesco|Tripodi, Marco|Ramacciato, Giovanni|Nigri, Giuseppe
PMID: 29456503
Journal: Oncotarget. 2017 Oct 16;8(60):101952-101964.
Title: Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway.
Author: Kim, Bo Ram|Jeong, Yoon A|Na, Yoo Jin|Park, Seong Hye|Jo, Min Jee|Kim, Jung Lim|Jeong, Soyeon|Lee, Suk-Young|Kim, Hong Jun|Oh, Sang Cheul|Lee, Dae-Hee
PMID: 29254217
Journal: Cell Rep. 2017 Dec 5;21(10):2813-2828.
Title: Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Author: Regan, Joseph L|Schumacher, Dirk|Staudte, Stephanie|Steffen, Andreas|Haybaeck, Johannes|Keilholz, Ulrich|Schweiger, Caroline|Golob-Schwarzl, Nicole|Mumberg, Dominik|Henderson, David|Lehrach, Hans|Regenbrecht, Christian R A|Schafer, Reinhold|Lange, Martin
PMID: 29212028
Journal: Eur Rev Med Pharmacol Sci. 2017 Nov;21(21):4853-4859.
Title: MiR-150 alleviates EMT and cell invasion of colorectal cancer through targeting Gli1.
Author: Fan, H|Liu, X|Zheng, W-W|Zhuang, Z-H|Wang, C-D
PMID: 29164577
Journal: Int J Mol Sci. 2017 Sep 1;18(9). pii: ijms18091888.
Title: Bromopropane Compounds Increase the Stemness of Colorectal Cancer Cells.
Author: Cho, Young-Chang|Nguyen, Thanh Thi|Park, So-Yeon|Kim, Kwonseop|Kim, Hyung Sik|Jeong, Hye Gwang|Kim, Kyung Keun|Kim, Hangun
PMID: 28862656
Journal: Oncol Rep. 2017 Oct;38(4):2087-2095.
Title: Zhi Zhen Fang formula reverses Hedgehog pathway mediated multidrug resistance in colorectal cancer.
Author: Sui, Hua|Duan, Peiwen|Guo, Piaoting|Hao, Lishuang|Liu, Xuan|Zhang, Jinhua|Zhu, Huirong|Zhao, Miaomiao|Wang, Hao|Li, Qi|Wang, Songpo
PMID: 28849164
Journal: Int J Cancer. 2017 Dec 15;141(12):2537-2550.
Title: Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers.
Author: Feng, Hsin-Chun|Lin, Jhuan-Yu|Hsu, Shu-Han|Lan, Wen-Yu|Kuo, Chang-Sheng|Tian, Yu-Feng|Sun, Ding-Ping|Huang, Rwei-Fen Syu
PMID: 28833104
Journal: Medicina (B Aires). 2017;77(4):283-290.
Title: Evaluation of cytotoxic and antitumoral properties of Tessaria absinthioides (Hook & Arn) DC, "pajaro bobo", aqueous extract.
Author: Persia, Fabio A|Rinaldini, Estefania|Carrion, Adriana|Hapon, Maria Belen|Gamarra-Luques, Carlos
PMID: 28825571
Journal: Exp Ther Med. 2017 May;13(5):2529-2536.
Title: Smoothened antagonist GDC-0449 (Vismodegib) inhibits proliferation and triggers apoptosis in colon cancer cell lines.
Author: Wu, Chuanqing|Hu, Shaobo|Cheng, Ji|Wang, Guobin|Tao, Kaixiong
PMID: 28565875
Journal: Oncol Res. 2017 May 24;25(5):681-689.
Title: FOXR2 Promotes the Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells.
Author: Lu, Sheng-Qiang|Qiu, Yan|Dai, Wei-Jie|Zhang, Xiao-Yu
PMID: 28548041
Journal: Cell Biosci. 2017 Apr 13;7:17.
Title: The role of GLI1 for 5-Fu resistance in colorectal cancer.
Author: Zhang, Lining|Song, Ruolan|Gu, Dongsheng|Zhang, Xiaoli|Yu, Beiqin|Liu, Bingya|Xie, Jingwu
PMID: 28413604
Journal: Cancer Res Treat. 2017 Oct;49(4):1077-1087.
Title: Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer.
Author: Lee, Si-Hyun|Kim, Hwang-Phill|Kang, Jun-Kyu|Song, Sang-Hyun|Han, Sae-Won|Kim, Tae-You
PMID: 28161934
Journal: Pathol Oncol Res. 2018 Jul;24(3):477-481.
Title: Intratumoral Heterogeneity of Frameshift Mutations of GLI1 Encoding a Hedgehog Signaling Protein in Colorectal Cancers.
Author: Lee, Ju Hwa|Song, Sang Yong|Kim, Min Sung|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 28664474
Journal: Mol Carcinog. 2018 Jul;57(7):911-925.
Title: Pseudopod-associated protein KIF20B promotes Gli1-induced epithelial-mesenchymal transition modulated by pseudopodial actin dynamic in human colorectal cancer.
Author: Lin, Wen-Feng|Lin, Xiao-Lu|Fu, Seng-Wang|Yang, Li|Tang, Chao-Tao|Gao, Yun-Jie|Chen, Hao-Yan|Ge, Zhi-Zheng
PMID: 29573464
Journal: Int J Mol Sci. 2018 Apr 6;19(4). pii: ijms19041098.
Title: Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture.
Author: Usui, Tatsuya|Sakurai, Masashi|Umata, Koji|Elbadawy, Mohamed|Ohama, Takashi|Yamawaki, Hideyuki|Hazama, Shoichi|Takenouchi, Hiroko|Nakajima, Masao|Tsunedomi, Ryouichi|Suzuki, Nobuaki|Nagano, Hiroaki|Sato, Koichi|Kaneda, Masahiro|Sasaki, Kazuaki
PMID: 29642386
Journal: Biochem Biophys Res Commun. 2018 Sep 18;503(4):3198-3204.
Title: The influence of aberrant expression of GLI1/p-S6K on colorectal cancer.
Author: Wang, Xuchao|Yao, Yizhou|Zhu, Xinguo
PMID: 30143258
Journal: Mol Cell Oncol. 2018 Apr 19;5(3):e1445940.
Title: Cell fate in colon cancer stem cells: To GLI or not to GLI?
Author: Regan, Joseph L
PMID: 30250897