Primary Site >> Colorectal Cancer
Gene >> GLI1
| 1. | |||||||||||
| Journal: | Cancer Res. 2000 Nov 15;60(22):6488-95. | ||||||||||
| Title: | Increase of GKLF messenger RNA and protein expression during progression of breast cancer. | ||||||||||
| Author: | Foster, K W|Frost, A R|McKie-Bell, P|Lin, C Y|Engler, J A|Grizzle, W E|Ruppert, J M | ||||||||||
| PMID: | 11103818 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Cancer. 2004 Jul 20;110(6):831-7. | ||||||||||
| Title: | Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. | ||||||||||
| Author: | Qualtrough, David|Buda, Andrea|Gaffield, William|Williams, Ann C|Paraskeva, Christos | ||||||||||
| PMID: | 15170664 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Oncol. 2005 Feb;26(2):545-9. | ||||||||||
| Title: | Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico. | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 15645142 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncol Rep. 2005 Oct;14(4):1087-90. | ||||||||||
| Title: | Comparative genomics on Sonic hedgehog orthologs. | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 16142377 | ||||||||||
| 5. | |||||||||||
| Journal: | Gut. 2006 Jul;55(7):991-9. Epub 2005 Nov 18. | ||||||||||
| Title: | Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation. | ||||||||||
| Author: | Akiyoshi, T|Nakamura, M|Koga, K|Nakashima, H|Yao, T|Tsuneyoshi, M|Tanaka, M|Katano, M | ||||||||||
| PMID: | 16299030 | ||||||||||
| 6. | |||||||||||
| Journal: | Surgery. 2006 May;139(5):665-70. | ||||||||||
| Title: | Sonic Hedgehog-dependent proliferation in a series of patients with colorectal cancer. | ||||||||||
| Author: | Douard, Richard|Moutereau, Stephane|Pernet, Pascal|Chimingqi, Mihelaiti|Allory, Yves|Manivet, Philippe|Conti, Marc|Vaubourdolle, Michel|Cugnenc, Paul-Henri|Loric, Sylvain | ||||||||||
| PMID: | 16701100 | ||||||||||
| 7. | |||||||||||
| Journal: | World J Gastroenterol. 2007 Mar 21;13(11):1659-65. | ||||||||||
| Title: | Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas. | ||||||||||
| Author: | Bian, Yue-Hong|Huang, Shu-Hong|Yang, Ling|Ma, Xiao-Li|Xie, Jing-Wu|Zhang, Hong-Wei | ||||||||||
| PMID: | 17461467 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Cancer. 2007 Dec 15;121(12):2622-7. | ||||||||||
| Title: | Hedgehog signaling pathway is inactive in colorectal cancer cell lines. | ||||||||||
| Author: | Chatel, Guillaume|Ganeff, Corine|Boussif, Naima|Delacroix, Laurence|Briquet, Alexandra|Nolens, Gregory|Winkler, Rosita | ||||||||||
| PMID: | 17683069 | ||||||||||
| 9. | |||||||||||
| Journal: | Virchows Arch. 2009 Apr;454(4):369-79. | ||||||||||
| Title: | Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation. | ||||||||||
| Author: | Alinger, Beate|Kiesslich, Tobias|Datz, Christian|Aberger, Fritz|Strasser, Felix|Berr, Frieder|Dietze, Otto|Kaserer, Klaus|Hauser-Kronberger, Cornelia | ||||||||||
| PMID: | 19280222 | ||||||||||
| 10. | |||||||||||
| Journal: | EMBO Mol Med. 2009 Sep;1(6-7):338-51. | ||||||||||
| Title: | Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. | ||||||||||
| Author: | Varnat, Frederic|Duquet, Arnaud|Malerba, Monica|Zbinden, Marie|Mas, Christophe|Gervaz, Pascal|Ruiz i Altaba, Ariel | ||||||||||
| PMID: | 20049737 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2009 Nov 15;69(22):8572-8. | ||||||||||
| Title: | Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA. | ||||||||||
| Author: | Noubissi, Felicite K|Goswami, Srikanta|Sanek, Nicholas A|Kawakami, Kazuyuki|Minamoto, Toshinari|Moser, Amy|Grinblat, Yevgenya|Spiegelman, Vladimir S | ||||||||||
| PMID: | 19887615 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Cell Biochem. 2010 Apr;337(1-2):185-92. | ||||||||||
| Title: | Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters. | ||||||||||
| Author: | Fu, Xiangsheng|Deng, Hong|Zhao, Luping|Li, Jing|Zhou, Yongbai|Zhang, Yali | ||||||||||
| PMID: | 19856079 | ||||||||||
| 13. | |||||||||||
| Journal: | Mech Dev. 2010 Jan-Feb;127(1-2):73-81. | ||||||||||
| Title: | Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling. | ||||||||||
| Author: | Varnat, Frederic|Zacchetti, Giovanna|Ruiz i Altaba, Ariel | ||||||||||
| PMID: | 19861162 | ||||||||||
| 14. | |||||||||||
| Journal: | PLoS One. 2010 Oct 1;5(10). pii: e13054. | ||||||||||
| Title: | cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. | ||||||||||
| Author: | Shi, Ting|Mazumdar, Tapati|Devecchio, Jennifer|Duan, Zhong-Hui|Agyeman, Akwasi|Aziz, Mohammad|Houghton, Janet A | ||||||||||
| PMID: | 20957031 | ||||||||||
| 15. | |||||||||||
| Journal: | Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1511-8. | ||||||||||
| Title: | Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro. | ||||||||||
| Author: | Wu, Jian-Ye|Xu, Xuan-Fu|Xu, Ling|Niu, Pei-Qin|Wang, Feng|Hu, Guo-Yong|Wang, Xing-Peng|Guo, Chuan-Yong | ||||||||||
| PMID: | 21940310 | ||||||||||
| 16. | |||||||||||
| Journal: | Sci Signal. 2011 Nov 22;4(200):pt9. | ||||||||||
| Title: | Hedgehog signaling and the Gli code in stem cells, cancer, and metastases. | ||||||||||
| Author: | Ruiz i Altaba, Ariel | ||||||||||
| PMID: | 22114144 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2011 Aug;2(8):638-45. | ||||||||||
| Title: | The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer. | ||||||||||
| Author: | Mazumdar, Tapati|DeVecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A | ||||||||||
| PMID: | 21860067 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Med Rep. 2011 Sep-Oct;4(5):873-7. | ||||||||||
| Title: | Differential expression profiles of the Hedgehog signaling pathway between microsatellite-stable and microsatellite-unstable colorectal cancers. | ||||||||||
| Author: | Hu, Xuguang|Lai, Daili|Chen, Wei|Zi, Shuming|Li, Jinming|Du, Peng|Wang, Zhongchuan|Huang, Shiyong|Long, Cui | ||||||||||
| PMID: | 21725600 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2011 Feb 1;71(3):1092-102. | ||||||||||
| Title: | Hedgehog signaling drives cellular survival in human colon carcinoma cells. | ||||||||||
| Author: | Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A | ||||||||||
| PMID: | 21135115 | ||||||||||
| 20. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Jul 15;17(14):4682-92. | ||||||||||
| Title: | Pharmacokinetic-pharmacodynamic analysis of vismodegib in preclinical models of mutational and ligand-dependent Hedgehog pathway activation. | ||||||||||
| Author: | Wong, Harvey|Alicke, Bruno|West, Kristina A|Pacheco, Patricia|La, Hank|Januario, Tom|Yauch, Robert L|de Sauvage, Frederic J|Gould, Stephen E | ||||||||||
| PMID: | 21610148 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2011 Sep 1;71(17):5904-14. | ||||||||||
| Title: | Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. | ||||||||||
| Author: | Mazumdar, Tapati|Devecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A | ||||||||||
| PMID: | 21747117 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2012 Aug;3(8):854-68. | ||||||||||
| Title: | Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer. | ||||||||||
| Author: | Agyeman, Akwasi|Mazumdar, Tapati|Houghton, Janet A | ||||||||||
| PMID: | 23097684 | ||||||||||
| 23. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(8):4001-5. | ||||||||||
| Title: | Expression of smoothened protein in colon cancer and its prognostic value for postoperative liver metastasis. | ||||||||||
| Author: | Ding, Yin-Lu|Wang, Qi-San|Zhao, Wei-Min|Xiang, Lei | ||||||||||
| PMID: | 23098507 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2012;7(9):e45332. | ||||||||||
| Title: | Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion. | ||||||||||
| Author: | Yoshimoto, Agnes N|Bernardazzi, Claudio|Carneiro, Antonio Jose V|Elia, Celeste C S|Martinusso, Cesonia A|Ventura, Grasiella M|Castelo-Branco, Morgana T L|de Souza, Heitor S P | ||||||||||
| PMID: | 23028941 | ||||||||||
| 25. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(5):2319-24. | ||||||||||
| Title: | Expression and clinical significance of hedgehog signaling pathway related components in colorectal cancer. | ||||||||||
| Author: | Wang, Hong|Li, Yu-Yuan|Wu, Ying-Ying|Nie, Yu-Qiang | ||||||||||
| PMID: | 22901214 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cancer Res. 2012 Sep;10(9):1147-57. | ||||||||||
| Title: | Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer. | ||||||||||
| Author: | Hwang, Rosa F|Moore, Todd T|Hattersley, Maureen Mertens|Scarpitti, Meghan|Yang, Bin|Devereaux, Erik|Ramachandran, Vijaya|Arumugam, Thiruvengadam|Ji, Baoan|Logsdon, Craig D|Brown, Jeffrey L|Godin, Robert | ||||||||||
| PMID: | 22859707 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Med Sci. 2012;9(5):334-8. | ||||||||||
| Title: | Expression of glioma-associated oncogene homolog 1 is associated with invasion and postoperative liver metastasis in colon cancer. | ||||||||||
| Author: | Ding, Yin-lu|Zhou, Yong|Xiang, Lei|Ji, Zhi-peng|Luo, Zhou-hong | ||||||||||
| PMID: | 22745574 | ||||||||||
| 28. | |||||||||||
| Journal: | Carcinogenesis. 2012 Jun;33(6):1158-68. | ||||||||||
| Title: | Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway. | ||||||||||
| Author: | Wang, Tz-Ping|Hsu, Shu-Han|Feng, Hsin-Chun|Huang, Rwei-Fen S | ||||||||||
| PMID: | 22461522 | ||||||||||
| 29. | |||||||||||
| Journal: | Exp Cell Res. 2012 Mar 10;318(5):539-49. | ||||||||||
| Title: | Abrogation of Gli3 expression suppresses the growth of colon cancer cells via activation of p53. | ||||||||||
| Author: | Kang, Han Na|Oh, Sang Cheul|Kim, Jun Suk|Yoo, Young A | ||||||||||
| PMID: | 22227409 | ||||||||||
| 30. | |||||||||||
| Journal: | Med Oncol. 2012 Jun;29(2):1010-6. | ||||||||||
| Title: | Prognostic value of hedgehog signaling pathway in patients with colon cancer. | ||||||||||
| Author: | Xu, Meihua|Li, Xinhua|Liu, Ting|Leng, Aimin|Zhang, Guiying | ||||||||||
| PMID: | 21424326 | ||||||||||
| 31. | |||||||||||
| Journal: | Int J Cancer. 2013 Jan 15;132(2):E18-25. | ||||||||||
| Title: | Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci. | ||||||||||
| Author: | Peng, Liang|Hu, Jingjing|Li, Shujun|Wang, Zhongqiu|Xia, Bingqing|Jiang, Bo|Li, Bingsheng|Zhang, Yu|Wang, Jing|Wang, Xinying | ||||||||||
| PMID: | 22945423 | ||||||||||
| 32. | |||||||||||
| Journal: | Am Surg. 2013 Feb;79(2):198-204. | ||||||||||
| Title: | Expression of GLI1 correlates with expression of lymphangiogenesis proteins, vascular endothelial growth factor C and vascular endothelial growth factor receptor 3, in colorectal cancer. | ||||||||||
| Author: | Hong, Kwang Dae|Lee, Youngseok|Kim, Baek-Hui|Lee, Sun Il|Moon, Hong Young | ||||||||||
| PMID: | 23336661 | ||||||||||
| 33. | |||||||||||
| Journal: | J Dig Dis. 2013 Aug;14(8):417-24. | ||||||||||
| Title: | Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli. | ||||||||||
| Author: | Wang, Zhong Chuan|Gao, Jun|Zi, Shu Ming|Yang, Ming|Du, Peng|Cui, Long | ||||||||||
| PMID: | 23551431 | ||||||||||
| 34. | |||||||||||
| Journal: | PLoS One. 2013 Jul 23;8(7):e69132. | ||||||||||
| Title: | Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer. | ||||||||||
| Author: | Chowdhury, Saikat|Pradhan, Rachana N|Sarkar, Ram Rup | ||||||||||
| PMID: | 23935937 | ||||||||||
| 35. | |||||||||||
| Journal: | PLoS One. 2013 Sep 25;8(9):e75253. | ||||||||||
| Title: | Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells. | ||||||||||
| Author: | Mazumdar, Tapati|Sandhu, Ranjodh|Qadan, Maha|DeVecchio, Jennifer|Magloire, Victoria|Agyeman, Akwasi|Li, Bibo|Houghton, Janet A | ||||||||||
| PMID: | 24086482 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncotarget. 2013 Dec;4(12):2208-11. | ||||||||||
| Title: | A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis. | ||||||||||
| Author: | Chung, Jon H|Bunz, Fred | ||||||||||
| PMID: | 24368541 | ||||||||||
| 37. | |||||||||||
| Journal: | PLoS One. 2014 Nov 11;9(11):e112700. | ||||||||||
| Title: | p, p'-Dichlorodiphenyldichloroethylene induces colorectal adenocarcinoma cell proliferation through oxidative stress. | ||||||||||
| Author: | Song, Li|Liu, Jianxin|Jin, Xiaoting|Li, Zhuoyu|Zhao, Meirong|Liu, Weiping | ||||||||||
| PMID: | 25386960 | ||||||||||
| 38. | |||||||||||
| Journal: | Clin Cancer Res. 2014 Mar 15;20(6):1687-97. | ||||||||||
| Title: | A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients. | ||||||||||
| Author: | Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin | ||||||||||
| PMID: | 24470513 | ||||||||||
| 39. | |||||||||||
| Journal: | Oncol Lett. 2014 Nov;8(5):2203-2208. | ||||||||||
| Title: | Hedgehog-glioma-associated oncogene homolog-1 signaling in colon cancer cells and its role in the celecoxib-mediated anti-cancer effect. | ||||||||||
| Author: | Wang, Hongtao|Ke, Fei|Zheng, Jie | ||||||||||
| PMID: | 25295109 | ||||||||||
| 40. | |||||||||||
| Journal: | Pharmacogenomics J. 2014 Apr;14(2):142-50. | ||||||||||
| Title: | Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence. | ||||||||||
| Author: | Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J | ||||||||||
| PMID: | 23817222 | ||||||||||
| 41. | |||||||||||
| Journal: | Oncotarget. 2014 Jun 30;5(12):4492-503. | ||||||||||
| Title: | Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding. | ||||||||||
| Author: | Agyeman, Akwasi|Jha, Babal K|Mazumdar, Tapati|Houghton, Janet A | ||||||||||
| PMID: | 24962990 | ||||||||||
| 42. | |||||||||||
| Journal: | Tumour Biol. 2015 Mar;36(3):2013-21. | ||||||||||
| Title: | beta1 integrin mediates colorectal cancer cell proliferation and migration through regulation of the Hedgehog pathway. | ||||||||||
| Author: | Song, Jia|Zhang, Jixiang|Wang, Jing|Wang, Jun|Guo, Xufeng|Dong, Weiguo | ||||||||||
| PMID: | 25387809 | ||||||||||
| 43. | |||||||||||
| Journal: | Clin Cancer Res. 2015 Mar 1;21(5):1002-9. | ||||||||||
| Title: | Phase I dose-escalation trial of the oral investigational Hedgehog signaling pathway inhibitor TAK-441 in patients with advanced solid tumors. | ||||||||||
| Author: | Goldman, Jonathan|Eckhardt, S Gail|Borad, Mitesh J|Curtis, Kelly K|Hidalgo, Manuel|Calvo, Emiliano|Ryan, David P|Wirth, Lori J|Parikh, Asit|Partyka, James|Faessel, Helene|Gangolli, Esha|Stewart, Sally|Rosen, Lee S|Bowles, Daniel W | ||||||||||
| PMID: | 25501576 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Biol Ther. 2015;16(1):1-7. | ||||||||||
| Title: | Crosstalk between Wnt/beta-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy. | ||||||||||
| Author: | Song, Li|Li, Zhuo-Yu|Liu, Wei-Ping|Zhao, Mei-Rong | ||||||||||
| PMID: | 25692617 | ||||||||||
| 45. | |||||||||||
| Journal: | Onco Targets Ther. 2015 Apr 17;8:877-83. | ||||||||||
| Title: | Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002. | ||||||||||
| Author: | Cai, Xinyi|Yu, Kun|Zhang, Lijuan|Li, Yunfeng|Li, Qiang|Yang, Zhibin|Shen, Tao|Duan, Lincan|Xiong, Wei|Wang, Weiya | ||||||||||
| PMID: | 25945059 | ||||||||||
| 46. | |||||||||||
| Journal: | Biochim Biophys Acta. 2015 Dec;1852(12):2574-84. | ||||||||||
| Title: | GSK3beta and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3beta downregulates the signaling pathway and reduces cell proliferation. | ||||||||||
| Author: | Trnski, Diana|Sabol, Maja|Gojevic, Ante|Martinic, Marina|Ozretic, Petar|Musani, Vesna|Ramic, Snjezana|Levanat, Sonja | ||||||||||
| PMID: | 26385428 | ||||||||||
| 47. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Sep 1;8(9):10092-101. eCollection 2015. | ||||||||||
| Title: | Inhibition of SALL4 suppresses carcinogenesis of colorectal cancer via regulating Gli1 expression. | ||||||||||
| Author: | Cheng, Ji|Deng, Rui|Wu, Chuanqing|Zhang, Peng|Wu, Ke|Shi, Liang|Liu, Xinghua|Bai, Jie|Deng, Meizhou|Gao, Jinbo|Shuai, Xiaoming|Wang, Guobin|Tao, Kaixiong | ||||||||||
| PMID: | 26617716 | ||||||||||
| 48. | |||||||||||
| Journal: | Int J Clin Exp Med. 2015 Nov 15;8(11):21379-85. eCollection 2015. | ||||||||||
| Title: | Dysregulation of hedgehog signaling pathway related components in the evolution of colonic carcinogenesis. | ||||||||||
| Author: | Zhang, Xu|Zhang, Sa-Sa|Wei, Gui-Jun|Deng, Zhong-Min|Hu, Yi | ||||||||||
| PMID: | 26885080 | ||||||||||
| 49. | |||||||||||
| Journal: | Heliyon. 2016 May 11;2(5):e00109. | ||||||||||
| Title: | Neoexpression of a functional primary cilium in colorectal cancer cells. | ||||||||||
| Author: | Senicourt, Blanche|Boudjadi, Salah|Carrier, Julie C|Beaulieu, Jean-Francois | ||||||||||
| PMID: | 27441280 | ||||||||||
| 50. | |||||||||||
| Journal: | Iran J Basic Med Sci. 2016 Nov;19(11):1171-1176. | ||||||||||
| Title: | The hedgehog/Gli-1 signaling pathways is involved in the inhibitory effect of resveratrol on human colorectal cancer HCT116 cells. | ||||||||||
| Author: | Du, Zhou|Zhou, Feng|Jia, Zengrong|Zheng, Beishi|Han, Shaoliang|Cheng, Jun|Zhu, Guanbao|Huang, Ping | ||||||||||
| PMID: | 27917272 | ||||||||||
| 51. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 27;7(52):86816-86828. | ||||||||||
| Title: | Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer. | ||||||||||
| Author: | Wang, Rong|Wei, Jinlai|Zhang, Shouru|Wu, Xingye|Guo, Jinbao|Liu, Maoxi|Du, Kunli|Xu, Jun|Peng, Linglong|Lv, Zhenbing|You, Wenxian|Xiong, Yongfu|Fu, Zhongxue | ||||||||||
| PMID: | 27894099 | ||||||||||
| 52. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 6;7(49):80190-80207. | ||||||||||
| Title: | Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing. | ||||||||||
| Author: | Zhang, Ruowen|Wu, Jiahui|Ferrandon, Sylvain|Glowacki, Katie J|Houghton, Janet A | ||||||||||
| PMID: | 27863397 | ||||||||||
| 53. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 27;7(52):86134-86147. | ||||||||||
| Title: | Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling. | ||||||||||
| Author: | Zhang, Chuan|Wang, Yong|Feng, YiFei|Zhang, Yue|Ji, Bing|Wang, Sen|Sun, Ye|Zhu, Chunyan|Zhang, Dongsheng|Sun, Yueming | ||||||||||
| PMID: | 27863385 | ||||||||||
| 54. | |||||||||||
| Journal: | Oncol Res. 2016;24(3):137-44. | ||||||||||
| Title: | Knockdown of PFTAIRE Protein Kinase 1 (PFTK1) Inhibits Proliferation, Invasion, and EMT in Colon Cancer Cells. | ||||||||||
| Author: | Zhu, Jiankang|Liu, Chongzhong|Liu, Fengyue|Wang, Yadong|Zhu, Min | ||||||||||
| PMID: | 27458094 | ||||||||||
| 55. | |||||||||||
| Journal: | Mol Pharmacol. 2016 Jun;89(6):606-17. | ||||||||||
| Title: | Inhibition of GLI1 Expression by Targeting the CRD-BP-GLI1 mRNA Interaction Using a Specific Oligonucleotide. | ||||||||||
| Author: | Mehmood, Kashif|Akhtar, Daud|Mackedenski, Sebastian|Wang, Chuyi|Lee, Chow H | ||||||||||
| PMID: | 27036131 | ||||||||||
| 56. | |||||||||||
| Journal: | Mol Pharmacol. 2016 Feb;89(2):226-32. | ||||||||||
| Title: | Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner. | ||||||||||
| Author: | Li, Bin|Giambelli, Camilla|Tang, Bo|Winterbottom, Emily|Long, Jun|Jin, Ke|Wang, Zhiqiang|Fei, Dennis Liang|Nguyen, Dao M|Athar, Mohammad|Wang, Baolin|Subbarayan, Pochi R|Wang, Lily|Rai, Priyamvada|Ardalan, Bach|Capobianco, Anthony J|Robbins, David J | ||||||||||
| PMID: | 26573582 | ||||||||||
| 57. | |||||||||||
| Journal: | J Mol Cell Biol. 2016 Apr;8(2):157-73. | ||||||||||
| Title: | In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases. | ||||||||||
| Author: | Singovski, Grigori|Bernal, Carolina|Kuciak, Monika|Siegl-Cachedenier, Irene|Conod, Arwen|Ruiz I Altaba, Ariel | ||||||||||
| PMID: | 26031752 | ||||||||||
| 58. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2017 Feb 2;36(1):23. | ||||||||||
| Title: | Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells. | ||||||||||
| Author: | Wang, DeJie|Hu, Guohui|Du, Ying|Zhang, Cheng|Lu, Quqin|Lv, Nonghua|Luo, Shiwen | ||||||||||
| PMID: | 28148279 | ||||||||||
| 59. | |||||||||||
| Journal: | Front Pharmacol. 2018 Feb 2;8:956. | ||||||||||
| Title: | SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer. | ||||||||||
| Author: | Magistri, Paolo|Battistelli, Cecilia|Strippoli, Raffaele|Petrucciani, Niccolo|Pellinen, Teijo|Rossi, Lucia|Mangogna, Livia|Aurello, Paolo|D'Angelo, Francesco|Tripodi, Marco|Ramacciato, Giovanni|Nigri, Giuseppe | ||||||||||
| PMID: | 29456503 | ||||||||||
| 60. | |||||||||||
| Journal: | Oncotarget. 2017 Oct 16;8(60):101952-101964. | ||||||||||
| Title: | Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway. | ||||||||||
| Author: | Kim, Bo Ram|Jeong, Yoon A|Na, Yoo Jin|Park, Seong Hye|Jo, Min Jee|Kim, Jung Lim|Jeong, Soyeon|Lee, Suk-Young|Kim, Hong Jun|Oh, Sang Cheul|Lee, Dae-Hee | ||||||||||
| PMID: | 29254217 | ||||||||||
| 61. | |||||||||||
| Journal: | Cell Rep. 2017 Dec 5;21(10):2813-2828. | ||||||||||
| Title: | Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells. | ||||||||||
| Author: | Regan, Joseph L|Schumacher, Dirk|Staudte, Stephanie|Steffen, Andreas|Haybaeck, Johannes|Keilholz, Ulrich|Schweiger, Caroline|Golob-Schwarzl, Nicole|Mumberg, Dominik|Henderson, David|Lehrach, Hans|Regenbrecht, Christian R A|Schafer, Reinhold|Lange, Martin | ||||||||||
| PMID: | 29212028 | ||||||||||
| 62. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2017 Nov;21(21):4853-4859. | ||||||||||
| Title: | MiR-150 alleviates EMT and cell invasion of colorectal cancer through targeting Gli1. | ||||||||||
| Author: | Fan, H|Liu, X|Zheng, W-W|Zhuang, Z-H|Wang, C-D | ||||||||||
| PMID: | 29164577 | ||||||||||
| 63. | |||||||||||
| Journal: | Int J Mol Sci. 2017 Sep 1;18(9). pii: ijms18091888. | ||||||||||
| Title: | Bromopropane Compounds Increase the Stemness of Colorectal Cancer Cells. | ||||||||||
| Author: | Cho, Young-Chang|Nguyen, Thanh Thi|Park, So-Yeon|Kim, Kwonseop|Kim, Hyung Sik|Jeong, Hye Gwang|Kim, Kyung Keun|Kim, Hangun | ||||||||||
| PMID: | 28862656 | ||||||||||
| 64. | |||||||||||
| Journal: | Oncol Rep. 2017 Oct;38(4):2087-2095. | ||||||||||
| Title: | Zhi Zhen Fang formula reverses Hedgehog pathway mediated multidrug resistance in colorectal cancer. | ||||||||||
| Author: | Sui, Hua|Duan, Peiwen|Guo, Piaoting|Hao, Lishuang|Liu, Xuan|Zhang, Jinhua|Zhu, Huirong|Zhao, Miaomiao|Wang, Hao|Li, Qi|Wang, Songpo | ||||||||||
| PMID: | 28849164 | ||||||||||
| 65. | |||||||||||
| Journal: | Int J Cancer. 2017 Dec 15;141(12):2537-2550. | ||||||||||
| Title: | Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. | ||||||||||
| Author: | Feng, Hsin-Chun|Lin, Jhuan-Yu|Hsu, Shu-Han|Lan, Wen-Yu|Kuo, Chang-Sheng|Tian, Yu-Feng|Sun, Ding-Ping|Huang, Rwei-Fen Syu | ||||||||||
| PMID: | 28833104 | ||||||||||
| 66. | |||||||||||
| Journal: | Medicina (B Aires). 2017;77(4):283-290. | ||||||||||
| Title: | Evaluation of cytotoxic and antitumoral properties of Tessaria absinthioides (Hook & Arn) DC, "pajaro bobo", aqueous extract. | ||||||||||
| Author: | Persia, Fabio A|Rinaldini, Estefania|Carrion, Adriana|Hapon, Maria Belen|Gamarra-Luques, Carlos | ||||||||||
| PMID: | 28825571 | ||||||||||
| 67. | |||||||||||
| Journal: | Exp Ther Med. 2017 May;13(5):2529-2536. | ||||||||||
| Title: | Smoothened antagonist GDC-0449 (Vismodegib) inhibits proliferation and triggers apoptosis in colon cancer cell lines. | ||||||||||
| Author: | Wu, Chuanqing|Hu, Shaobo|Cheng, Ji|Wang, Guobin|Tao, Kaixiong | ||||||||||
| PMID: | 28565875 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncol Res. 2017 May 24;25(5):681-689. | ||||||||||
| Title: | FOXR2 Promotes the Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells. | ||||||||||
| Author: | Lu, Sheng-Qiang|Qiu, Yan|Dai, Wei-Jie|Zhang, Xiao-Yu | ||||||||||
| PMID: | 28548041 | ||||||||||
| 69. | |||||||||||
| Journal: | Cell Biosci. 2017 Apr 13;7:17. | ||||||||||
| Title: | The role of GLI1 for 5-Fu resistance in colorectal cancer. | ||||||||||
| Author: | Zhang, Lining|Song, Ruolan|Gu, Dongsheng|Zhang, Xiaoli|Yu, Beiqin|Liu, Bingya|Xie, Jingwu | ||||||||||
| PMID: | 28413604 | ||||||||||
| 70. | |||||||||||
| Journal: | Cancer Res Treat. 2017 Oct;49(4):1077-1087. | ||||||||||
| Title: | Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer. | ||||||||||
| Author: | Lee, Si-Hyun|Kim, Hwang-Phill|Kang, Jun-Kyu|Song, Sang-Hyun|Han, Sae-Won|Kim, Tae-You | ||||||||||
| PMID: | 28161934 | ||||||||||
| 71. | |||||||||||
| Journal: | Pathol Oncol Res. 2018 Jul;24(3):477-481. | ||||||||||
| Title: | Intratumoral Heterogeneity of Frameshift Mutations of GLI1 Encoding a Hedgehog Signaling Protein in Colorectal Cancers. | ||||||||||
| Author: | Lee, Ju Hwa|Song, Sang Yong|Kim, Min Sung|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 28664474 | ||||||||||
| 72. | |||||||||||
| Journal: | Mol Carcinog. 2018 Jul;57(7):911-925. | ||||||||||
| Title: | Pseudopod-associated protein KIF20B promotes Gli1-induced epithelial-mesenchymal transition modulated by pseudopodial actin dynamic in human colorectal cancer. | ||||||||||
| Author: | Lin, Wen-Feng|Lin, Xiao-Lu|Fu, Seng-Wang|Yang, Li|Tang, Chao-Tao|Gao, Yun-Jie|Chen, Hao-Yan|Ge, Zhi-Zheng | ||||||||||
| PMID: | 29573464 | ||||||||||
| 73. | |||||||||||
| Journal: | Int J Mol Sci. 2018 Apr 6;19(4). pii: ijms19041098. | ||||||||||
| Title: | Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture. | ||||||||||
| Author: | Usui, Tatsuya|Sakurai, Masashi|Umata, Koji|Elbadawy, Mohamed|Ohama, Takashi|Yamawaki, Hideyuki|Hazama, Shoichi|Takenouchi, Hiroko|Nakajima, Masao|Tsunedomi, Ryouichi|Suzuki, Nobuaki|Nagano, Hiroaki|Sato, Koichi|Kaneda, Masahiro|Sasaki, Kazuaki | ||||||||||
| PMID: | 29642386 | ||||||||||
| 74. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2018 Sep 18;503(4):3198-3204. | ||||||||||
| Title: | The influence of aberrant expression of GLI1/p-S6K on colorectal cancer. | ||||||||||
| Author: | Wang, Xuchao|Yao, Yizhou|Zhu, Xinguo | ||||||||||
| PMID: | 30143258 | ||||||||||
| 75. | |||||||||||
| Journal: | Mol Cell Oncol. 2018 Apr 19;5(3):e1445940. | ||||||||||
| Title: | Cell fate in colon cancer stem cells: To GLI or not to GLI? | ||||||||||
| Author: | Regan, Joseph L | ||||||||||
| PMID: | 30250897 | ||||||||||