Primary Site >> Colorectal Cancer
Gene >> GCLC
| 1. | |||||||||||
| Journal: | Biochem Pharmacol. 1995 Oct 12;50(8):1233-8. | ||||||||||
| Title: | Influence of ethacrynic acid on glutathione S-transferase pi transcript and protein half-lives in human colon cancer cells. | ||||||||||
| Author: | Shen, H|Ranganathan, S|Kuzmich, S|Tew, K D | ||||||||||
| PMID: | 7488239 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 1996 Aug 15;56(16):3642-4. | ||||||||||
| Title: | Frequent coordinated overexpression of the MRP/GS-X pump and gamma-glutamylcysteine synthetase genes in human colorectal cancers. | ||||||||||
| Author: | Kuo, M T|Bao, J J|Curley, S A|Ikeguchi, M|Johnston, D A|Ishikawa, T | ||||||||||
| PMID: | 8705999 | ||||||||||
| 3. | |||||||||||
| Journal: | J Clin Invest. 1996 Sep 1;98(5):1210-7. | ||||||||||
| Title: | Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz. | ||||||||||
| Author: | O'Dwyer, P J|Szarka, C E|Yao, K S|Halbherr, T C|Pfeiffer, G R|Green, F|Gallo, J M|Brennan, J|Frucht, H|Goosenberg, E B|Hamilton, T C|Litwin, S|Balshem, A M|Engstrom, P F|Clapper, M L | ||||||||||
| PMID: | 8787684 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Pharmacol. 1998 Mar 1;55(5):605-15. | ||||||||||
| Title: | Frequent coexpression of MRP/GS-X pump and gamma-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues. | ||||||||||
| Author: | Kuo, M T|Bao, J|Furuichi, M|Yamane, Y|Gomi, A|Savaraj, N|Masuzawa, T|Ishikawa, T | ||||||||||
| PMID: | 9515571 | ||||||||||
| 5. | |||||||||||
| Journal: | Clin Chem Lab Med. 2000 Sep;38(9):893-7. | ||||||||||
| Title: | The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design. | ||||||||||
| Author: | Ishikawa, T|Kuo, M T|Furuta, K|Suzuki, M | ||||||||||
| PMID: | 11097346 | ||||||||||
| 6. | |||||||||||
| Journal: | Biochem Pharmacol. 2001 Mar 1;61(5):555-63. | ||||||||||
| Title: | Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status. | ||||||||||
| Author: | Lin-Lee, Y C|Tatebe, S|Savaraj, N|Ishikawa, T|Tien Kuo, M | ||||||||||
| PMID: | 11239498 | ||||||||||
| 7. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2001 Aug 17;286(2):406-13. | ||||||||||
| Title: | Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression. | ||||||||||
| Author: | Nagata, J|Kijima, H|Hatanaka, H|Asai, S|Miyachi, H|Takagi, A|Miwa, T|Mine, T|Yamazaki, H|Nakamura, M|Kondo, T|Scanlon, K J|Ueyama, Y | ||||||||||
| PMID: | 11500053 | ||||||||||
| 8. | |||||||||||
| Journal: | J Nutr. 2002 Jun;132(6):1376-9. | ||||||||||
| Title: | Red wine and black tea polyphenols modulate the expression of cycloxygenase-2, inducible nitric oxide synthase and glutathione-related enzymes in azoxymethane-induced f344 rat colon tumors. | ||||||||||
| Author: | Luceri, Cristina|Caderni, Giovanna|Sanna, Anna|Dolara, Piero | ||||||||||
| PMID: | 12042461 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2002 Jan 1;97(1):21-7. | ||||||||||
| Title: | Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma. | ||||||||||
| Author: | Tatebe, Shigeru|Unate, Hitoshi|Sinicrope, Frank A|Sakatani, Takashi|Sugamura, Kenji|Makino, Masato|Ito, Hisao|Savaraj, Niramol|Kaibara, Nobuaki|Kuo, M Tien | ||||||||||
| PMID: | 11774239 | ||||||||||
| 10. | |||||||||||
| Journal: | J Agric Food Chem. 2009 Feb 25;57(4):1579-88. | ||||||||||
| Title: | Calvatia lilacina protein-extract induces apoptosis through glutathione depletion in human colorectal carcinoma cells. | ||||||||||
| Author: | Tsay, Jwu-Guh|Chung, King-Thom|Yeh, Chung-Hung|Chen, Wan-Ling|Chen, Chi-Hung|Lin, Martin Hsiu-Chu|Lu, Fung-Jou|Chiou, Jeng-Fong|Chen, Ching-Hsein | ||||||||||
| PMID: | 19182949 | ||||||||||
| 11. | |||||||||||
| Journal: | Molecules. 2010 May 7;15(5):3338-55. | ||||||||||
| Title: | The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. | ||||||||||
| Author: | Wondrak, Georg Thomas|Villeneuve, Nicole F|Lamore, Sarah D|Bause, Alexandra S|Jiang, Tao|Zhang, Donna D | ||||||||||
| PMID: | 20657484 | ||||||||||
| 12. | |||||||||||
| Journal: | Toxicol In Vitro. 2011 Apr;25(3):671-83. | ||||||||||
| Title: | Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. | ||||||||||
| Author: | Niestroy, Jeanette|Barbara, Alfonso|Herbst, Kathrin|Rode, Sandra|van Liempt, Manuela|Roos, Peter H | ||||||||||
| PMID: | 21256954 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Med Rep. 2015 Sep;12(3):4314-4319. | ||||||||||
| Title: | Involvement of glutathione and glutathione metabolizing enzymes in human colorectal cancer cell lines and tissues. | ||||||||||
| Author: | Kim, Areum Daseul|Zhang, Rui|Han, Xia|Kang, Kyoung Ah|Piao, Mei Jing|Maeng, Young Hee|Chang, Weon Young|Hyun, Jin Won | ||||||||||
| PMID: | 26059756 | ||||||||||
| 14. | |||||||||||
| Journal: | Free Radic Res. 2016;50(1):1-13. | ||||||||||
| Title: | The proteasome inhibitor lactacystin enhances GSH synthesis capacity by increased expression of antioxidant components in an Nrf2-independent, but p38 MAPK-dependent manner in rat colorectal carcinoma cells. | ||||||||||
| Author: | Huseby, Nils-Erik|Ravuri, Chandra|Moens, Ugo | ||||||||||
| PMID: | 26530909 | ||||||||||
| 15. | |||||||||||
| Journal: | J Clin Invest. 2016 Feb;126(2):681-94. | ||||||||||
| Title: | PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis. | ||||||||||
| Author: | Nguyen, Alexander|Loo, Jia Min|Mital, Rohit|Weinberg, Ethan M|Man, Fung Ying|Zeng, Zhaoshi|Paty, Philip B|Saltz, Leonard|Janjigian, Yelena Y|de Stanchina, Elisa|Tavazoie, Sohail F | ||||||||||
| PMID: | 26784545 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 19;7(29):46219-46229. | ||||||||||
| Title: | Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer. | ||||||||||
| Author: | Jang, Hyun Joo|Hong, Eun Mi|Kim, Mikang|Kim, Jae Hyun|Jang, Juah|Park, Se Woo|Byun, Hyun Wu|Koh, Dong Hee|Choi, Min Ho|Kae, Sea Hyub|Lee, Jin | ||||||||||
| PMID: | 27323826 | ||||||||||
| 17. | |||||||||||
| Journal: | Inflamm Bowel Dis. 2016 Nov;22(11):2593-2606. | ||||||||||
| Title: | Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes. | ||||||||||
| Author: | Kruse, Marie-Luise|Friedrich, Martin|Arlt, Alexander|Rocken, Christoph|Egberts, Jan-Hendrik|Sebens, Susanne|Schafer, Heiner | ||||||||||
| PMID: | 27661668 | ||||||||||