Primary Site >> Liver Cancer
Gene >> GADD45B
| 1. | |||||||||||
| Journal: | Am J Pathol. 2003 Jun;162(6):1961-74. | ||||||||||
| Title: | Down-regulation of growth arrest DNA damage-inducible gene 45beta expression is associated with human hepatocellular carcinoma. | ||||||||||
| Author: | Qiu, Weihua|David, Donald|Zhou, Bingsen|Chu, Peiguo G|Zhang, Bohe|Wu, Mengchao|Xiao, Jiacheng|Han, Tianquan|Zhu, Zhenggang|Wang, Tianxiang|Liu, Xiyong|Lopez, Richard|Frankel, Paul|Jong, Ambrose|Yen, Yun | ||||||||||
| PMID: | 12759252 | ||||||||||
| 2. | |||||||||||
| Journal: | Carcinogenesis. 2003 Apr;24(4):757-70. | ||||||||||
| Title: | Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643. | ||||||||||
| Author: | Iida, Mari|Anna, Colleen H|Hartis, Jennifer|Bruno, Maribel|Wetmore, Barbara|Dubin, Joshua R|Sieber, Stella|Bennett, Lee|Cunningham, Michael L|Paules, Richard S|Tomer, Kenneth B|Houle, Christopher D|Merrick, Alex B|Sills, Robert C|Devereux, Theodora R | ||||||||||
| PMID: | 12727805 | ||||||||||
| 3. | |||||||||||
| Journal: | Am J Pathol. 2004 Nov;165(5):1689-99. | ||||||||||
| Title: | Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma. | ||||||||||
| Author: | Qiu, Weihua|Zhou, Bingsen|Zou, Hongzhi|Liu, Xiyong|Chu, Peiguo G|Lopez, Richard|Shih, Jennifer|Chung, Christopher|Yen, Yun | ||||||||||
| PMID: | 15509538 | ||||||||||
| 4. | |||||||||||
| Journal: | Carcinogenesis. 2005 Mar;26(3):689-99. | ||||||||||
| Title: | Unique patterns of gene expression changes in liver after treatment of mice for 2 weeks with different known carcinogens and non-carcinogens. | ||||||||||
| Author: | Iida, Mari|Anna, Colleen H|Holliday, Wanda M|Collins, Jennifer B|Cunningham, Michael L|Sills, Robert C|Devereux, Theodora R | ||||||||||
| PMID: | 15618236 | ||||||||||
| 5. | |||||||||||
| Journal: | Toxicol Sci. 2007 Sep;99(1):43-50. | ||||||||||
| Title: | The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b. | ||||||||||
| Author: | Iida, Mari|Anna, Colleen H|Gaskin, Nicole D|Walker, Nigel J|Devereux, Theodora R | ||||||||||
| PMID: | 17533171 | ||||||||||
| 6. | |||||||||||
| Journal: | Am J Pathol. 2007 Jul;171(1):287-96. | ||||||||||
| Title: | The induction of growth arrest DNA damage-inducible gene 45 beta in human hepatoma cell lines by S-adenosylmethionine. | ||||||||||
| Author: | Qiu, Weihua|Zhou, Bingsen|Chu, Peiguo G|Luh, Frank|Yen, Yun | ||||||||||
| PMID: | 17591973 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Sci. 2007 Nov;98(11):1758-66. | ||||||||||
| Title: | Interferon-gamma sensitizes hepatitis B virus-expressing hepatocarcinoma cells to 5-fluorouracil through inhibition of hepatitis B virus-mediated nuclear factor-kappaB activation. | ||||||||||
| Author: | Chung, Chan|Park, Sung Gyoo|Park, Young Min|Joh, Jae-Won|Jung, Guhung | ||||||||||
| PMID: | 17711513 | ||||||||||
| 8. | |||||||||||
| Journal: | Anticancer Res. 2007 Nov-Dec;27(6B):3783-9. | ||||||||||
| Title: | A sequential treatment of depsipeptide followed by 5-azacytidine enhances Gadd45beta expression in hepatocellular carcinoma cells. | ||||||||||
| Author: | Jiang, Chunling|Zhou, Bingsen|Fan, Kenneth|Heung, Eric|Xue, Lijun|Liu, Xiyong|Kirschbaum, Mark|Yen, Yun | ||||||||||
| PMID: | 18225533 | ||||||||||
| 9. | |||||||||||
| Journal: | BMC Genomics. 2008 Oct 16;9:487. | ||||||||||
| Title: | Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT. | ||||||||||
| Author: | Kiyosawa, Naoki|Kwekel, Joshua C|Burgoon, Lyle D|Dere, Edward|Williams, Kurt J|Tashiro, Colleen|Chittim, Brock|Zacharewski, Timothy R | ||||||||||
| PMID: | 18925944 | ||||||||||
| 10. | |||||||||||
| Journal: | Toxicol Sci. 2009 Aug;110(2):319-33. | ||||||||||
| Title: | The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors. | ||||||||||
| Author: | Phillips, Jennifer M|Burgoon, Lyle D|Goodman, Jay I | ||||||||||
| PMID: | 19482888 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2010 Apr 12;5(4):e10121. | ||||||||||
| Title: | Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. | ||||||||||
| Author: | Yamamoto, Yukio|Moore, Rick|Flavell, Richard A|Lu, Binfeng|Negishi, Masahiko | ||||||||||
| PMID: | 20404936 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2010 Nov 15;70(22):9309-18. | ||||||||||
| Title: | Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. | ||||||||||
| Author: | Ou, Da-Liang|Shen, Ying-Chun|Yu, Sung-Liang|Chen, Kuen-Feng|Yeh, Pei-Yen|Fan, Hsiang-Hsuan|Feng, Wen-Chi|Wang, Ching-Tzu|Lin, Liang-In|Hsu, Chiun|Cheng, Ann-Lii | ||||||||||
| PMID: | 21062976 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biol Chem. 2011 Feb 4;286(5):3570-8. | ||||||||||
| Title: | Pregnane X receptor PXR activates the GADD45beta gene, eliciting the p38 MAPK signal and cell migration. | ||||||||||
| Author: | Kodama, Susumu|Negishi, Masahiko | ||||||||||
| PMID: | 21127053 | ||||||||||
| 14. | |||||||||||
| Journal: | J Viral Hepat. 2011 Oct;18(10):e439-46. | ||||||||||
| Title: | Involvement of the NF-kappaB pathway in multidrug resistance induced by HBx in a hepatoma cell line. | ||||||||||
| Author: | Liu, Y|Lou, G|Wu, W|Zheng, M|Shi, Y|Zhao, D|Chen, Z | ||||||||||
| PMID: | 21914061 | ||||||||||
| 15. | |||||||||||
| Journal: | Adv Exp Med Biol. 2013;793:69-80. | ||||||||||
| Title: | Gadd45 in the liver: signal transduction and transcriptional mechanisms. | ||||||||||
| Author: | Tian, Jianmin|Locker, Joseph | ||||||||||
| PMID: | 24104474 | ||||||||||
| 16. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2013 Sep 1;271(2):137-43. | ||||||||||
| Title: | Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERalpha in mouse livers. | ||||||||||
| Author: | Kazantseva, Yuliya A|Yarushkin, Andrei A|Pustylnyak, Vladimir O | ||||||||||
| PMID: | 23684557 | ||||||||||
| 17. | |||||||||||
| Journal: | Toxicol In Vitro. 2013 Sep;27(6):1809-19. | ||||||||||
| Title: | Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. | ||||||||||
| Author: | Straser, Alja|Filipic, Metka|Zegura, Bojana | ||||||||||
| PMID: | 23726867 | ||||||||||
| 18. | |||||||||||
| Journal: | Virol J. 2013 May 29;10:168. | ||||||||||
| Title: | Interferon-alpha sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-kappaB activation. | ||||||||||
| Author: | Liu, Yanning|Lou, Guohua|Wu, Wei|Shi, Yu|Zheng, Min|Chen, Zhi | ||||||||||
| PMID: | 23718853 | ||||||||||
| 19. | |||||||||||
| Journal: | Gene. 2013 Apr 10;518(1):201-8. | ||||||||||
| Title: | In-silico drug screening and potential target identification for hepatocellular carcinoma using Support Vector Machines based on drug screening result. | ||||||||||
| Author: | Yang, Wu-Lung R|Lee, Yu-En|Chen, Ming-Huang|Chao, Kun-Mao|Huang, Chi-Ying F | ||||||||||
| PMID: | 23220021 | ||||||||||
| 20. | |||||||||||
| Journal: | Curr Pharm Des. 2014;20(11):1715-25. | ||||||||||
| Title: | Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis. | ||||||||||
| Author: | Rongrui, Liang|Na, Huang|Zongfang, Li|Fanpu, Ji|Shiwen, Jiang | ||||||||||
| PMID: | 23888939 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2014 Mar 1;74(5):1452-62. | ||||||||||
| Title: | Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes. | ||||||||||
| Author: | Ma, Leina|Liu, Jia|Liu, Limei|Duan, Guangjie|Wang, Qingliang|Xu, Yanmin|Xia, Feng|Shan, Juanjuan|Shen, Junjie|Yang, Zhi|Bie, Ping|Cui, Youhong|Bian, Xiu-Wu|Prieto, Jesus|Avila, Matias A|Qian, Cheng | ||||||||||
| PMID: | 24390737 | ||||||||||
| 22. | |||||||||||
| Journal: | Toxicol Sci. 2014 Nov;142(1):137-57. | ||||||||||
| Title: | Human hepatocytes support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogen sodium phenobarbital in an in vivo study using a chimeric mouse with humanized liver. | ||||||||||
| Author: | Yamada, Tomoya|Okuda, Yu|Kushida, Masahiko|Sumida, Kayo|Takeuchi, Hayato|Nagahori, Hirohisa|Fukuda, Takako|Lake, Brian G|Cohen, Samuel M|Kawamura, Satoshi | ||||||||||
| PMID: | 25145657 | ||||||||||
| 23. | |||||||||||
| Journal: | Environ Toxicol Pharmacol. 2014 Nov;38(3):742-50. | ||||||||||
| Title: | Altered gene expression in HepG2 cells exposed to a methanolic coal dust extract. | ||||||||||
| Author: | Guerrero-Castilla, Angelica|Olivero-Verbel, Jesus | ||||||||||
| PMID: | 25305735 | ||||||||||
| 24. | |||||||||||
| Journal: | Clin Epigenetics. 2016 Apr 30;8:46. | ||||||||||
| Title: | Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7. | ||||||||||
| Author: | Sajadian, Sahar Olsadat|Tripura, Chaturvedula|Samani, Fazel Sahraneshin|Ruoss, Marc|Dooley, Steven|Baharvand, Hossein|Nussler, Andreas K | ||||||||||
| PMID: | 27134688 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 14;7(24):37215-37225. | ||||||||||
| Title: | GADD45beta induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia. | ||||||||||
| Author: | Ma, Ding|Shen, Baiyong|Seewoo, Varun|Tong, Hui|Yang, Weiping|Cheng, Xi|Jin, Zhijian|Peng, Chenghong|Qiu, Weihua | ||||||||||
| PMID: | 27177086 | ||||||||||
| 26. | |||||||||||
| Journal: | Cell Death Discov. 2017 Sep 11;3:17058. | ||||||||||
| Title: | Simultaneous silencing of ACSL4 and induction of GADD45B in hepatocellular carcinoma cells amplifies the synergistic therapeutic effect of aspirin and sorafenib. | ||||||||||
| Author: | Xia, Hongping|Lee, Kee Wah|Chen, Jianxiang|Kong, Shik Nie|Sekar, Karthik|Deivasigamani, Amudha|Seshachalam, Veerabrahma Pratap|Goh, Brian Kim Poh|Ooi, London Lucien|Hui, Kam M | ||||||||||
| PMID: | 28900541 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Biosci. 2017 Dec 6;7:63. | ||||||||||
| Title: | Methylation mediated Gadd45beta enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells. | ||||||||||
| Author: | Hou, Xiao-Juan|Zhao, Qiu-Dong|Jing, Ying-Ying|Han, Zhi-Peng|Yang, Xue|Wei, Li-Xin|Zheng, Yu-Ting|Xie, Feng|Zhang, Bai-He | ||||||||||
| PMID: | 29225771 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Res. 2018 Mar 1;78(5):1275-1292. | ||||||||||
| Title: | GADD45beta Loss Ablates Innate Immunosuppression in Cancer. | ||||||||||
| Author: | Verzella, Daniela|Bennett, Jason|Fischietti, Mariafausta|Thotakura, Anil K|Recordati, Camilla|Pasqualini, Fabio|Capece, Daria|Vecchiotti, Davide|D'Andrea, Daniel|Di Francesco, Barbara|De Maglie, Marcella|Begalli, Federica|Tornatore, Laura|Papa, Salvatore| | ||||||||||
| PMID: | 29279355 | ||||||||||
| 29. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Aug;16(8):1309-1318. | ||||||||||
| Title: | Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver. | ||||||||||
| Author: | Hori, Takeshi|Saito, Kosuke|Moore, Rick|Flake, Gordon P|Negishi, Masahiko | ||||||||||
| PMID: | 29716964 | ||||||||||
| 30. | |||||||||||
| Journal: | Genes (Basel). 2018 Jul 19;9(7). pii: genes9070361. | ||||||||||
| Title: | GADD45B as a Prognostic and Predictive Biomarker in Stage II Colorectal Cancer. | ||||||||||
| Author: | Zhao, Zhixun|Gao, Yibo|Guan, Xu|Liu, Zheng|Jiang, Zheng|Liu, Xiuyun|Lin, Huixin|Yang, Ming|Li, Chunxiang|Yang, Runkun|Zou, Shuangmei|Wang, Xishan | ||||||||||
| PMID: | 30029519 | ||||||||||
| 31. | |||||||||||
| Journal: | Toxicol Sci. 2018 Oct 22. pii: 5140222. | ||||||||||
| Title: | Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b. | ||||||||||
| Author: | Lu, Peipei|Cai, Xinran|Guo, Yan|Xu, Meishu|Tian, Jianmin|Locker, Joseph|Xie, Wen | ||||||||||
| PMID: | 30346592 | ||||||||||