Primary Site >> Colorectal Cancer

Gene >> GADD45A

Journal: Hybridoma. 1995 Aug;14(4):355-9.
Title: The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein.
Author: Kilpatrick, K E|Carrier, F|Smith, M L|Chen, C Y|Lee, A J|Rusnak, D W|Kastan, M B|Fornace, A J Jr|Champion, B R|Gilmer, T M
PMID: 8522347
Journal: Cancer Res. 1996 Feb 15;56(4):840-7.
Title: An abnormality in the p53 pathway following gamma-irradiation in many wild-type p53 human melanoma lines.
Author: Bae, I|Smith, M L|Sheikh, M S|Zhan, Q|Scudiero, D A|Friend, S H|O'Connor, P M|Fornace, A J Jr
PMID: 8631022
Journal: Oncogene. 1996 Nov 21;13(10):2255-63.
Title: Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin.
Author: Smith, M L|Kontny, H U|Zhan, Q|Sreenath, A|O'Connor, P M|Fornace, A J Jr
PMID: 8950993
Journal: Oncol Res. 1996;8(7-8):317-23.
Title: Differential GADD45, p21CIP1/WAF1, MCL-1 and topoisomerase II gene induction and secondary DNA fragmentation after camptothecin-induced DNA damage in two mutant p53 human colon cancer cell lines.
Author: Goldwasser, F|Bae, I|Fornace, A J Jr|Pommier, Y
PMID: 8938795
Journal: Exp Cell Res. 1997 Jan 10;230(1):61-8.
Title: The p53-regulated cyclin G gene promotes cell growth: p53 downstream effectors cyclin G and Gadd45 exert different effects on cisplatin chemosensitivity.
Author: Smith, M L|Kontny, H U|Bortnick, R|Fornace, A J Jr
PMID: 9013707
Journal: Cancer Res. 2001 Jul 1;61(13):5193-201.
Title: Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
Author: Meyers, M|Wagner, M W|Hwang, H S|Kinsella, T J|Boothman, D A
PMID: 11431359
Journal: Cancer Lett. 2002 Dec 15;188(1-2):127-40.
Title: Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells.
Author: Chen, Zunxuan|Clark, Steven|Birkeland, Marian|Sung, Chiu Mei|Lago, Amparo|Liu, Ronggang|Kirkpatrick, Robert|Johanson, Kyung|Winkler, James D|Hu, Erding
PMID: 12406558
Journal: Mol Cancer Ther. 2002 Apr;1(6):377-84.
Title: Inhibition of cell growth by NB1011 requires high thymidylate synthase levels and correlates with p53, p21, bax, and GADD45 induction.
Author: Neuteboom, Saskia T C|Karjian, Patricia L|Boyer, Christopher R|Beryt, Malgorzhata|Pegram, Mark|Wahl, Geoffrey M|Shepard, H Michael
PMID: 12477050
Journal: J Cell Biochem. 2003 Dec 15;90(6):1128-39.
Title: Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells.
Author: Powolny, Anna|Takahashi, Keiko|Hopkins, Robin G|Loo, George
PMID: 14635187
Journal: Zhonghua Yi Xue Za Zhi. 2003 Nov 10;83(21):1895-9.
Title: [Suppression of HCT116 growth of cells by Gadd45].
Author: Tong, Tong|Song, Yong-mei|Fu, Ming|Dong, Li-jia|Jin, Shun-qian|Wu, Min|Zhan, Qi-min
PMID: 14642075
Journal: J Nutr. 2003 Aug;133(8):2682-7.
Title: Down-regulation of proliferating cell nuclear antigen gene expression occurs during cell cycle arrest induced by human fecal water in colonic HT-29 cells.
Author: Zeng, Huawei|Davis, Cindy D
PMID: 12888658
Journal: Nihon Eiseigaku Zasshi. 2003 May;58(2):267-74.
Title: [Gene-regulating chemoprevention against cancer--as a model for "molecular-targeting prevention" of cancer].
Author: Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 12806965
Journal: J Nutr Biochem. 2003 Apr;14(4):227-31.
Title: Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver(1,2).
Author: Zeng, Huawei|Davis, Cindy D|Finley, John W
PMID: 12770647
Journal: Int J Oncol. 2004 May;24(5):1279-88.
Title: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil.
Author: de Angelis, Paula M|Fjell, Bjorg|Kravik, Katherine L|Haug, Terje|Tunheim, Siv H|Reichelt, Wenche|Beigi, Marzieh|Clausen, Ole Petter|Galteland, Eivind|Stokke, Trond
PMID: 15067352
Journal: Biochem Biophys Res Commun. 2004 Nov 12;324(2):878-86.
Title: Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells.
Author: Maaser, Kerstin|Sutter, Andreas P|Krahn, Antje|Hopfner, Michael|Grabowski, Patricia|Scherubl, Hans
PMID: 15474510
Journal: J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16.
Title: 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Author: Schneider-Stock, Regine|Diab-Assef, Mona|Rohrbeck, Astrid|Foltzer-Jourdainne, Charlotte|Boltze, Carsten|Hartig, Roland|Schonfeld, Peter|Roessner, Albert|Gali-Muhtasib, Hala
PMID: 15547111
Journal: Mol Cancer Ther. 2005 Jun;4(6):901-9.
Title: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.
Author: Li, Yin|Mao, Yuehua|Brandt-Rauf, Paul W|Williams, Ann C|Fine, Robert L
PMID: 15956247
Journal: Prostaglandins Leukot Essent Fatty Acids. 2005 Aug;73(2):113-9.
Title: Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco-2 cells.
Author: Yasui, Yumiko|Hosokawa, Masashi|Sahara, Takehiko|Suzuki, Rikako|Ohgiya, Satoru|Kohno, Hiroyuki|Tanaka, Takuji|Miyashita, Kazuo
PMID: 15961301
Journal: Int J Oncol. 2005 Dec;27(6):1727-36.
Title: Differential gene expression of sulindac-treated human breast epithelial cells.
Author: Roy, D|Panda, A|Calaf, G M|Mitra, A
PMID: 16273229
Journal: Surg Today. 2006;36(7):608-14.
Title: cDNA array analysis for prediction of hepatic metastasis of colorectal carcinoma.
Author: Takata, Osamu|Kawamura, Yutaka J|Konishi, Fumio|Sasaki, Junichi|Kai, Toshihiro|Miyakura, Yasuyuki|Nagai, Hideo|Tsukamoto, Toshihiko
PMID: 16794795
Journal: Mol Cancer. 2006 May 18;5:20.
Title: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery.
Author: De Angelis, Paula M|Svendsrud, Debbie H|Kravik, Katherine L|Stokke, Trond
PMID: 16709241
Journal: Oncogene. 2007 Nov 29;26(54):7517-25. Epub 2007 Jun 18.
Title: Base excision DNA repair defect in Gadd45a-deficient cells.
Author: Jung, H J|Kim, E H|Mun, J-Y|Park, S|Smith, M L|Han, S S|Seo, Y R
PMID: 17599061
Journal: Gut. 2009 Mar;58(3):413-20.
Title: Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial.
Author: Dronamraju, S S|Coxhead, J M|Kelly, S B|Burn, J|Mathers, J C
PMID: 18978177
Journal: J Cell Biochem. 2009 Dec 1;108(5):1220-31.
Title: Distinct mechanisms are utilized to induce stress sensor gadd45b by different stress stimuli.
Author: Zumbrun, Steven D|Hoffman, Barbara|Liebermann, Dan A
PMID: 19834918
Journal: Nutr Cancer. 2010;62(1):105-15.
Title: Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair.
Author: Dronamraju, Shridhar S|Coxhead, Jonathan M|Kelly, Seamus B|Mathers, John C
PMID: 20043265
Journal: J Cancer Res Clin Oncol. 2010 Aug;136(8):1267-73.
Title: Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis.
Author: Zhang, Wei|Li, Tianrun|Shao, Yong|Zhang, Chao|Wu, Qi|Yang, Hong|Zhang, Jie|Guan, Ming|Yu, Bo|Wan, Jun
PMID: 20111973
Journal: BMC Cancer. 2010 May 5;10:180.
Title: Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Author: van Roon, Eddy H J|van Puijenbroek, Marjo|Middeldorp, Anneke|van Eijk, Ronald|de Meijer, Emile J|Erasmus, Dianhdra|Wouters, Kim A D|van Engeland, Manon|Oosting, Jan|Hes, Frederik J|Tops, Carli M J|van Wezel, Tom|Boer, Judith M|Morreau, Hans
PMID: 20444249
Journal: Oncology. 2012;82(3):153-64.
Title: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author: Fernandez-Marcelo, Tamara|Moran, Alberto|de Juan, Carmen|Pascua, Irene|Head, Jacqueline|Gomez, Ana|Hernando, Florentino|Lopez-Asenjo, Jose A|Hernandez, Susana|Sanchez-Pernaute, Andres|Torres, Antonio J|Benito, Manuel|Iniesta, Pilar
PMID: 22433385
Journal: Cell Res. 2012 Aug;22(8):1285-303.
Title: N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents.
Author: Song, Shanshan|Xing, Guichun|Yuan, Lin|Wang, Jian|Wang, Shan|Yin, Yuxin|Tian, Chunyan|He, Fuchu|Zhang, Lingqiang
PMID: 22801474
Journal: Br J Nutr. 2012 Aug;108 Suppl 1:S145-54.
Title: Non-digestible fraction of beans (Phaseolus vulgaris L.) modulates signalling pathway genes at an early stage of colon cancer in Sprague-Dawley rats.
Author: Hayde, Vergara-Castaneda|Ramon, Guevara-Gonzalez|Lorenzo, Guevara-Olvera|Dave, Oomah B|Rosalia, Reynoso-Camacho|Paul, Wiersma|Guadalupe, Loarca-Pina
PMID: 22916810
Journal: Mol Biol Rep. 2013 Nov;40(11):6351-61.
Title: Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.
Author: Storcelova, Maria|Vician, Marian|Reis, Richard|Zeman, Michal|Herichova, Iveta
PMID: 24062075
Journal: Cancer Lett. 2014 Mar 1;344(1):110-8.
Title: Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.
Author: Germani, Aldo|Matrone, Antonio|Grossi, Valentina|Peserico, Alessia|Sanese, Paola|Liuzzi, Micaela|Palermo, Rocco|Murzilli, Stefania|Campese, Antonio Francesco|Ingravallo, Giuseppe|Canettieri, Gianluca|Tezil, Tugsan|Simone, Cristiano
PMID: 24215867
Journal: Mol Med Rep. 2014 Jul;10(1):486-90.
Title: Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair.
Author: Wu, Xiao-Yu|Chen, Che|Yao, Xue-Quan|Cao, Qin-Hong|Xu, Zhe|Li, Wei-Su|Liu, Fu-Kun|Li, Gang
PMID: 24788673
Journal: J Pharmacol Exp Ther. 2015 Jun;353(3):561-2.
Title: Correction to "5-aza-Cytidine Is a Potent Inhibitor of DNA Methyltransferase 3a and Induces Apoptosis in HCT-116 Colon Cancer Cells via Gadd45- and p53-Dependent Mechanisms".
Author:
PMID: 25934763
Journal: Oncotarget. 2015 Aug 7;6(22):18780-9.
Title: MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression.
Author: Kim, Taewan|Cui, Ri|Jeon, Young-Jun|Fadda, Paolo|Alder, Hansjuerg|Croce, Carlo M
PMID: 26003165
Journal: J Pharmacol Exp Ther. 2016 Oct;359(1):90.
Title: Re: Schneider-Stock R, Diab-Assef M, Rohrbeck A, Foltzer-Jourdainne C, Boltze C, Hartig R, Schonfeld P, Roessner A, and Gali-Muhtasib H (2005) 5-aza-Cytidine Is a Potent Inhibitor of DNA Methyltransferase 3a and Induces Apoptosis in HCT-116 Colon Cancer C
Author:
PMID: 27581647
Journal: Life Sci. 2016 Dec 15;167:67-77.
Title: Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells.
Author: Eyvani, Haniyeh|Moghaddaskho, Farima|Kabuli, Majid|Zekri, Ali|Momeny, Majid|Tavakkoly-Bazzaz, Javad|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir|Ghaffari, Seyed H
PMID: 27769816
Journal: PLoS One. 2017 Jan 9;12(1):e0168989.
Title: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author: Huang, Wen-Shih|Kuo, Yi-Hung|Kuo, Hsing-Chun|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Lee, Ko-Chao|Lee, Kam-Fai|Shen, Chien-Heng|Tung, Shui-Yi|Teng, Chih-Chuan
PMID: 28068431
Journal: Biochim Biophys Acta Gene Regul Mech. 2017 Apr;1860(4):516-522.
Title: CRIF1 enhances p53 activity via the chromatin remodeler SNF5 in the HCT116 colon cancer cell lines.
Author: Yan, Hai-Xia|Zhang, Yan-Jun|Zhang, Yuan|Ren, Xue|Shen, Yu-Fei|Cheng, Mo-Bin|Zhang, Ye
PMID: 28235567
Journal: Int J Oncol. 2018 Aug;53(2):750-760.
Title: Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs.
Author: Su, Meng-Qi|Zhou, Yi-Ran|Rao, Xuan|Yang, Hong|Zhuang, Xin-Hao|Ke, Xue-Jia|Peng, Guang-Yong|Zhou, Chang-Lin|Shen, Bai-Yong|Dou, Jie
PMID: 29749481
Journal: Int J Mol Sci. 2018 Jun 29;19(7). pii: ijms19071909.
Title: The Curcumin Analog CH-5 Exerts Anticancer Effects in Human Osteosarcoma Cells via Modulation of Transcription Factors p53/Sp1.
Author: Lima, Felipe Teixeira|Seba, Viviane|Silva, Gabriel|Torrezan, Guilherme Silva|Polaquini, Carlos Roberto|Pinhanelli, Vitor Caressato|Baek, Seung J|Fachin, Ana Lucia|Regasini, Luis Octavio|Marins, Mozart
PMID: 29966255