Primary Site >> Liver Cancer

Gene >> G6PC

Journal: J Gastroenterol Hepatol. 1999 Jun;14(6):553-8.
Title: Case report: Hepatocellular carcinoma in type 1a glycogen storage disease with identification of a glucose-6-phosphatase gene mutation in one family.
Author: Nakamura, T|Ozawa, T|Kawasaki, T|Yasumi, K|Wang, D Y|Kitagawa, M|Takehira, Y|Tamakoshi, K|Yamada, M|Kida, H|Sugie, H|Nakamura, H|Sugimura, H
PMID: 10385064
Journal: J Gastroenterol Hepatol. 2001 Dec;16(12):1402-8.
Title: Glucose-6-phosphatase gene mutations in 20 adult Japanese patients with glycogen storage disease type 1a with reference to hepatic tumors.
Author: Nakamura, T|Ozawa, T|Kawasaki, T|Nakamura, H|Sugimura, H
PMID: 11851840
Journal: J Hepatol. 2010 Jul;53(1):213-7.
Title: An adult male patient with multiple adenomas and a hepatocellular carcinoma: mild glycogen storage disease type Ia.
Author: Cassiman, David|Libbrecht, Louis|Verslype, Chris|Meersseman, Wouter|Troisi, Roberto|Zucman-Rossi, Jessica|Van Vlierberghe, Hans
PMID: 20447711
Journal: Intern Med. 2011;50(20):2317-22. Epub 2011 Oct 15.
Title: Abdominal imaging findings of a patient with hepatocellular carcinoma associated with glycogen storage disease type 1a.
Author: Ochi, Hironori|Hiraoka, Atsushi|Uehara, Takahide|Hidaka, Satoshi|Kawasaki, Hideki|Furuya, Keizou|Hirooka, Masashi|Abe, Masanori|Matsuura, Bunzo|Hiasa, Yoichi|Onji, Morikazu|Michitaka, Kojiro
PMID: 22001457
Journal: Hepatology. 2012 Jul;56(1):186-97.
Title: Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
Author: Wang, Bo|Hsu, Shu-Hao|Frankel, Wendy|Ghoshal, Kalpana|Jacob, Samson T
PMID: 22318941
Journal: Gene. 2012 Nov 1;509(1):154-7.
Title: Misdiagnosis as steatohepatitis in a family with mild glycogen storage disease type 1a.
Author: Shieh, Jeng-Jer|Lu, Yung-Hsiu|Huang, Shi-Wei|Huang, Yu-Hsiu|Sun, Chih-Hao|Chiou, Hong-Jen|Liu, Chinsu|Lo, Ming-Yu|Lin, Ching-Yuang|Niu, Dau-Ming
PMID: 22909800
Journal: Dis Model Mech. 2014 Sep;7(9):1083-91.
Title: Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-alpha deficiency.
Author: Resaz, Roberta|Vanni, Cristina|Segalerba, Daniela|Sementa, Angela R|Mastracci, Luca|Grillo, Federica|Murgia, Daniele|Bosco, Maria Carla|Chou, Janice Y|Barbieri, Ottavia|Varesio, Luigi|Eva, Alessandra
PMID: 25147298
Journal: Cell Death Discov. 2015 Sep 7;1:15016.
Title: mTORC2 controls cancer cell survival by modulating gluconeogenesis.
Author: Khan, M W|Biswas, D|Ghosh, M|Mandloi, S|Chakrabarti, S|Chakrabarti, P
PMID: 27551450
Journal: Mol Genet Metab. 2017 Mar;120(3):229-234.
Title: Glycogen storage disease type Ia mice with less than 2% of normal hepatic glucose-6-phosphatase-alpha activity restored are at risk of developing hepatic tumors.
Author: Kim, Goo-Young|Lee, Young Mok|Kwon, Joon Hyun|Cho, Jun-Ho|Pan, Chi-Jiunn|Starost, Matthew F|Mansfield, Brian C|Chou, Janice Y
PMID: 28096054
Journal: Liver Res. 2017 Sep;1(3):174-180.
Title: Recent development and gene therapy for glycogen storage disease type Ia.
Author: Chou, Janice Y|Kim, Goo-Young|Cho, Jun-Ho
PMID: 29576889
Journal: Biochem Biophys Res Commun. 2018 Apr 15;498(4):925-931.
Title: Hepatic glucose-6-phosphatase-alpha deficiency leads to metabolic reprogramming in glycogen storage disease type Ia.
Author: Cho, Jun-Ho|Kim, Goo-Young|Mansfield, Brian C|Chou, Janice Y
PMID: 29545180
Journal: Mol Metab. 2018 Oct;16:100-115.
Title: Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context.
Author: Monteillet, Laure|Gjorgjieva, Monika|Silva, Marine|Verzieux, Vincent|Imikirene, Linda|Duchampt, Adeline|Guillou, Herve|Mithieux, Gilles|Rajas, Fabienne
PMID: 30100243
Journal: J Hepatol. 2018 Sep 4. pii: S0168-8278(18)32271-2.
Title: Dietary exacerbation of metabolic stress leads to accelerated hepatic carcinogenesis in glycogen storage disease type Ia.
Author: Gjorgjieva, Monika|Calderaro, Julien|Monteillet, Laure|Silva, Marine|Raffin, Margaux|Brevet, Marie|Romestaing, Caroline|Roussel, Damien|Zucman-Rossi, Jessica|Mithieux, Gilles|Rajas, Fabienne
PMID: 30193922