Primary Site >> Colorectal Cancer
Gene >> FURIN
| 1. | |||||||||||
| Journal: | J Biol Chem. 1993 Dec 15;268(35):26461-5. | ||||||||||
| Title: | Evidence for involvement of furin in cleavage and activation of diphtheria toxin. | ||||||||||
| Author: | Tsuneoka, M|Nakayama, K|Hatsuzawa, K|Komada, M|Kitamura, N|Mekada, E | ||||||||||
| PMID: | 8253774 | ||||||||||
| 2. | |||||||||||
| Journal: | FEBS Lett. 1993 Aug 9;328(1-2):25-9. | ||||||||||
| Title: | Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin. | ||||||||||
| Author: | Komada, M|Hatsuzawa, K|Shibamoto, S|Ito, F|Nakayama, K|Kitamura, N | ||||||||||
| PMID: | 8344430 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer. 1993 Nov 1;72(9 Suppl):2842-5. | ||||||||||
| Title: | Reimbursement issues facing patients, providers, and payers. | ||||||||||
| Author: | Antman, K | ||||||||||
| PMID: | 8402516 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1993 Sep 15;195(2):1019-26. | ||||||||||
| Title: | A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells. | ||||||||||
| Author: | Takahashi, S|Kasai, K|Hatsuzawa, K|Kitamura, N|Misumi, Y|Ikehara, Y|Murakami, K|Nakayama, K | ||||||||||
| PMID: | 7690548 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 1995 Nov 3;270(44):26565-9. | ||||||||||
| Title: | A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation. | ||||||||||
| Author: | Takahashi, S|Nakagawa, T|Kasai, K|Banno, T|Duguay, S J|Van de Ven, W J|Murakami, K|Nakayama, K | ||||||||||
| PMID: | 7592877 | ||||||||||
| 6. | |||||||||||
| Journal: | Biochem J. 1995 Jul 1;309 ( Pt 1):33-40. | ||||||||||
| Title: | Direct role of furin in mammalian prosomatostatin processing. | ||||||||||
| Author: | Galanopoulou, A S|Seidah, N G|Patel, Y C | ||||||||||
| PMID: | 7619075 | ||||||||||
| 7. | |||||||||||
| Journal: | J Virol. 1995 May;69(5):3206-10. | ||||||||||
| Title: | Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus. | ||||||||||
| Author: | Watanabe, M|Hirano, A|Stenglein, S|Nelson, J|Thomas, G|Wong, T C | ||||||||||
| PMID: | 7707552 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 2000 Feb 15;60(4):877-82. | ||||||||||
| Title: | Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors. | ||||||||||
| Author: | Velasco, G|Cal, S|Merlos-Suarez, A|Ferrando, A A|Alvarez, S|Nakano, A|Arribas, J|Lopez-Otin, C | ||||||||||
| PMID: | 10706098 | ||||||||||
| 9. | |||||||||||
| Journal: | Public Health. 2000 Sep;114(5):308-15. | ||||||||||
| Title: | Physical activity and cause-specific mortality in the Whitehall study. | ||||||||||
| Author: | Davey Smith, G|Shipley, M J|Batty, G D|Morris, J N|Marmot, M | ||||||||||
| PMID: | 11035446 | ||||||||||
| 10. | |||||||||||
| Journal: | Adv Cancer Res. 2001;80:83-114. | ||||||||||
| Title: | Genetic predisposition and somatic diversification in tumor development and progression. | ||||||||||
| Author: | Shibata, D|Aaltonen, L A | ||||||||||
| PMID: | 11034541 | ||||||||||
| 11. | |||||||||||
| Journal: | J Biol Chem. 2001 Aug 17;276(33):30686-93. Epub 2001 Jun 11. | ||||||||||
| Title: | Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions. | ||||||||||
| Author: | Khatib, A M|Siegfried, G|Prat, A|Luis, J|Chretien, M|Metrakos, P|Seidah, N G | ||||||||||
| PMID: | 11402025 | ||||||||||
| 12. | |||||||||||
| Journal: | Gastrointest Endosc Clin N Am. 2002 Jan;12(1):85-91. | ||||||||||
| Title: | Does virtual colonoscopy have a major role in population-based screening? | ||||||||||
| Author: | Hawes, Robert H | ||||||||||
| PMID: | 11916164 | ||||||||||
| 13. | |||||||||||
| Journal: | Gene. 2002 Nov 13;301(1-2):31-41. | ||||||||||
| Title: | Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer. | ||||||||||
| Author: | Ahokas, Katja|Lohi, Jouko|Lohi, Hannes|Elomaa, Outi|Karjalainen-Lindsberg, Marja Liisa|Kere, Juha|Saarialho-Kere, Ulpu | ||||||||||
| PMID: | 12490321 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Res. 2003 Apr 1;63(7):1458-63. | ||||||||||
| Title: | The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity. | ||||||||||
| Author: | Siegfried, Geraldine|Khatib, Abdel-Majid|Benjannet, Suzanne|Chretien, Michel|Seidah, Nabil G | ||||||||||
| PMID: | 12670890 | ||||||||||
| 15. | |||||||||||
| Journal: | Biochem J. 2003 Jul 15;373(Pt 2):475-84. | ||||||||||
| Title: | Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage. | ||||||||||
| Author: | Bergeron, Eric|Basak, Ajoy|Decroly, Etienne|Seidah, Nabil G | ||||||||||
| PMID: | 12691605 | ||||||||||
| 16. | |||||||||||
| Journal: | J Clin Invest. 2003 Jun;111(11):1723-32. | ||||||||||
| Title: | The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. | ||||||||||
| Author: | Siegfried, Geraldine|Basak, Ajoy|Cromlish, James A|Benjannet, Suzanne|Marcinkiewicz, Jadwiga|Chretien, Michel|Seidah, Nabil G|Khatib, Abdel-Majid | ||||||||||
| PMID: | 12782675 | ||||||||||
| 17. | |||||||||||
| Journal: | Traffic. 2004 Aug;5(8):627-41. | ||||||||||
| Title: | Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells. | ||||||||||
| Author: | Deryugina, Elena I|Ratnikov, Boris I|Yu, Qing|Baciu, Peter C|Rozanov, Dmitri V|Strongin, Alex Y | ||||||||||
| PMID: | 15260832 | ||||||||||
| 18. | |||||||||||
| Journal: | J BUON. 2005 Apr-Jun;10(2):227-34. | ||||||||||
| Title: | A preclinical survey on the efficacy of lactandrate in the treatment of colon carcinoma. | ||||||||||
| Author: | Trafalis, D T P|Geromichalos, G D|Bountouroglou, N|Koumbi, D|Kontos, M|Sougias, D|Dalezis, P|Karamanakos, P|Papageorgiou, A|Camoutsis, C|Athanassiou, A E | ||||||||||
| PMID: | 17343334 | ||||||||||
| 19. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2005 Nov 11;337(1):232-40. | ||||||||||
| Title: | Proteolytic processing of the ovine prion protein in cell cultures. | ||||||||||
| Author: | Tveit, Heidi|Lund, Christoffer|Olsen, Christel M|Ersdal, Cecilie|Prydz, Kristian|Harbitz, Ingrid|Tranulis, Michael A | ||||||||||
| PMID: | 16182247 | ||||||||||
| 20. | |||||||||||
| Journal: | N Engl J Med. 2005 Jun 30;352(26):2746-8. | ||||||||||
| Title: | Adjuvant therapy for colon cancer--the pace quickens. | ||||||||||
| Author: | Allegra, Carmen|Sargent, Daniel J | ||||||||||
| PMID: | 15987925 | ||||||||||
| 21. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2005 Jan;37(1):142-54. | ||||||||||
| Title: | Membrane type-1 matrix metalloproteinase (MT1-MMP) protects malignant cells from tumoricidal activity of re-engineered anthrax lethal toxin. | ||||||||||
| Author: | Rozanov, Dmitri V|Golubkov, Vladislav S|Strongin, Alex Y | ||||||||||
| PMID: | 15381157 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Reprod Dev. 2005 Dec;72(4):483-93. | ||||||||||
| Title: | Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development. | ||||||||||
| Author: | St Germain, Carly|Croissandeau, Gilles|Mayne, Janice|Baltz, Jay M|Chretien, Michel|Mbikay, Majambu | ||||||||||
| PMID: | 16163737 | ||||||||||
| 23. | |||||||||||
| Journal: | Korean J Gastroenterol. 2007 May;49(5):271-9. | ||||||||||
| Title: | [Future direction of nanomedicine in gastrointestinal cancer]. | ||||||||||
| Author: | Song, Si Young | ||||||||||
| PMID: | 17525514 | ||||||||||
| 24. | |||||||||||
| Journal: | J Gen Virol. 2007 Jul;88(Pt 7):1859-65. | ||||||||||
| Title: | Proteolytic cleavage of glycoprotein B is dispensable for in vitro replication, but required for syncytium formation of pseudorabies virus. | ||||||||||
| Author: | Okazaki, Katsunori | ||||||||||
| PMID: | 17554016 | ||||||||||
| 25. | |||||||||||
| Journal: | J Clin Invest. 2008 Jan;118(1):352-63. | ||||||||||
| Title: | Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. | ||||||||||
| Author: | Scamuffa, Nathalie|Siegfried, Geraldine|Bontemps, Yannick|Ma, Liming|Basak, Ajoy|Cherel, Ghislaine|Calvo, Fabien|Seidah, Nabil G|Khatib, Abdel-Majid | ||||||||||
| PMID: | 18064302 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Cancer. 2008 Apr 15;122(8):1695-700. | ||||||||||
| Title: | Colorectal cancer cells express functional cell surface-bound TGFbeta. | ||||||||||
| Author: | Baker, Kristi|Raut, Pooja|Jass, Jeremy R | ||||||||||
| PMID: | 18076044 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2009;4(4):e5031. | ||||||||||
| Title: | Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site. | ||||||||||
| Author: | Gawlik, Katarzyna|Shiryaev, Sergey A|Zhu, Wenhong|Motamedchaboki, Khatereh|Desjardins, Roxane|Day, Robert|Remacle, Albert G|Stec, Boguslaw|Strongin, Alex Y | ||||||||||
| PMID: | 19352504 | ||||||||||
| 28. | |||||||||||
| Journal: | Hypertension. 2009 Jun;53(6):1077-82. | ||||||||||
| Title: | Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. | ||||||||||
| Author: | Cousin, Christelle|Bracquart, Diane|Contrepas, Aurelie|Corvol, Pierre|Muller, Laurent|Nguyen, Genevieve | ||||||||||
| PMID: | 19380613 | ||||||||||
| 29. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2010 Mar;49(3):270-81. | ||||||||||
| Title: | Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression. | ||||||||||
| Author: | Forsti, Asta|Li, Xuchen|Wagner, Kerstin|Tavelin, Bjorn|Enquist, Kerstin|Palmqvist, Richard|Altieri, Andrea|Hallmans, Goran|Hemminki, Kari|Lenner, Per | ||||||||||
| PMID: | 19998449 | ||||||||||
| 30. | |||||||||||
| Journal: | Ann Epidemiol. 2010 Sep;20(9):661-9. | ||||||||||
| Title: | Walking pace, leisure time physical activity, and resting heart rate in relation to disease-specific mortality in London: 40 years follow-up of the original Whitehall study. An update of our work with professor Jerry N. Morris (1910-2009). | ||||||||||
| Author: | Batty, G David|Shipley, Martin J|Kivimaki, Mika|Marmot, Michael|Davey Smith, George | ||||||||||
| PMID: | 20579904 | ||||||||||
| 31. | |||||||||||
| Journal: | Mol Ther. 2012 Jan;20(1):46-53. | ||||||||||
| Title: | 2A peptide-based, lentivirus-mediated anti-death receptor 5 chimeric antibody expression prevents tumor growth in nude mice. | ||||||||||
| Author: | Li, Meng|Wu, Yaomin|Qiu, Yuhe|Yao, Zhenyu|Liu, Shilian|Liu, Yanxin|Shi, Juan|Zheng, Dexian | ||||||||||
| PMID: | 21934654 | ||||||||||
| 32. | |||||||||||
| Journal: | Virchows Arch. 2012 Sep;461(3):231-43. | ||||||||||
| Title: | Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer : future possibilities for personalised treatment by use of biomarkers. | ||||||||||
| Author: | de Cuba, E M V|Kwakman, R|van Egmond, M|Bosch, L J W|Bonjer, H J|Meijer, G A|te Velde, E A | ||||||||||
| PMID: | 22825001 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Biol Cell. 2013 Feb;24(4):465-73. | ||||||||||
| Title: | beta-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-alpha suppresses caspase-8 activation in apoptosis-resistant colon cancer cells. | ||||||||||
| Author: | Han, Jinbo|Sridevi, Priya|Ramirez, Michael|Ludwig, Kirsten J|Wang, Jean Y J | ||||||||||
| PMID: | 23264463 | ||||||||||
| 34. | |||||||||||
| Journal: | Support Care Cancer. 2013 Aug;21(8):2289-96. | ||||||||||
| Title: | Virtual navigation in colorectal cancer and melanoma: an exploration of patients' views. | ||||||||||
| Author: | Loiselle, Carmen G|Peters, Okimi|Haase, Kristen R|Girouard, Laurence|Korner, Annett|Wiljer, David|Fitch, Margaret | ||||||||||
| PMID: | 23519565 | ||||||||||
| 35. | |||||||||||
| Journal: | Nat Rev Gastroenterol Hepatol. 2013 Dec;10(12):741-5. | ||||||||||
| Title: | Functional genomic analyses of the gut microbiota for CRC screening. | ||||||||||
| Author: | Konstantinov, Sergey R|Kuipers, Ernst J|Peppelenbosch, Maikel P | ||||||||||
| PMID: | 24042452 | ||||||||||
| 36. | |||||||||||
| Journal: | J Biol Chem. 2013 Nov 29;288(48):34956-67. | ||||||||||
| Title: | Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface. | ||||||||||
| Author: | Shiryaev, Sergey A|Remacle, Albert G|Chernov, Andrei V|Golubkov, Vladislav S|Motamedchaboki, Khatereh|Muranaka, Norihito|Dambacher, Corey M|Capek, Petr|Kukreja, Muskan|Kozlov, Igor A|Perucho, Manuel|Cieplak, Piotr|Strongin, Alex Y | ||||||||||
| PMID: | 24145028 | ||||||||||
| 37. | |||||||||||
| Journal: | Eur J Cancer Prev. 2015 Mar;24(2):155-61. | ||||||||||
| Title: | Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA. | ||||||||||
| Author: | Iwasaki, Motoki|Franke, Adrian A|Hamada, Gerson S|Miyajima, Nelson T|Sharma, Sangita|Ishihara, Junko|Takachi, Ribeka|Tsugane, Shoichiro|Le Marchand, Loic | ||||||||||
| PMID: | 25633435 | ||||||||||
| 38. | |||||||||||
| Journal: | Biomed Res Int. 2015;2015:321276. | ||||||||||
| Title: | Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer. | ||||||||||
| Author: | Declercq, Jeroen|Jacobs, Bart|Biesmans, Bart|Roth, Arnaud|Klingbiel, Dirk|Tejpar, Sabine|Creemers, John W | ||||||||||
| PMID: | 26137475 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Epidemiol. 2016 Feb;40:113-8. | ||||||||||
| Title: | Contribution of changes in demography and in the risk factors to the predicted pattern of cancer mortality among Spanish women by 2022. | ||||||||||
| Author: | Cleries, Ramon|Buxo, Maria|Martinez, Jose M|Espinas, Josep A|Dyba, Tadeusz|Borras, Josep M | ||||||||||
| PMID: | 26707236 | ||||||||||
| 40. | |||||||||||
| Journal: | Cell Death Dis. 2017 Mar 9;8(3):e2665. | ||||||||||
| Title: | Long noncoding RNA BLACAT1 indicates a poor prognosis of colorectal cancer and affects cell proliferation by epigenetically silencing of p15. | ||||||||||
| Author: | Su, Jun|Zhang, Erbao|Han, Liang|Yin, Dandan|Liu, Zhili|He, Xuezhi|Zhang, Yuhong|Lin, Feng|Lin, Qingfeng|Mao, Peiyao|Mao, Weidong|Shen, Dong | ||||||||||
| PMID: | 28277544 | ||||||||||
| 41. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jun 4;9(6):673. | ||||||||||
| Title: | Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis. | ||||||||||
| Author: | Pan, Shengli|Deng, Yingying|Fu, Jun|Zhang, Yuhao|Zhang, Zhijin|Ru, Xiaokun|Qin, Xianju | ||||||||||
| PMID: | 29867200 | ||||||||||
| 42. | |||||||||||
| Journal: | Carcinogenesis. 2018 Aug 9. pii: 5068270. | ||||||||||
| Title: | Semaphorin-3A inhibits multiple myeloma progression in a mouse model. | ||||||||||
| Author: | Lavi, Noa|Kessler, Ofra|Ziv, Keren|Nir-Zvi, Inbal|Mumblat, Yelena|Eiza, Nasrene|Paran, Yael|Brenner, Benjamin|Vadasz, Zahava|Neufeld, Gera | ||||||||||
| PMID: | 30102336 | ||||||||||