Primary Site >> Colorectal Cancer
Gene >> FPGS
| 1. | |||||||||||
| Journal: | Ann Oncol. 1995 Nov;6(9):871-81. | ||||||||||
| Title: | Folate-based thymidylate synthase inhibitors as anticancer drugs. | ||||||||||
| Author: | Jackman, A L|Calvert, A H | ||||||||||
| PMID: | 8624289 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncol Res. 1995;7(6):317-21. | ||||||||||
| Title: | Screening of colon tumor cells and tissues for folylpolyglutamate synthetase activity. | ||||||||||
| Author: | van der Wilt, C L|Cloos, J|de Jong, M|Pinedo, H M|Peters, G J | ||||||||||
| PMID: | 8527866 | ||||||||||
| 3. | |||||||||||
| Journal: | Ann Oncol. 1996 Mar;7(3):283-9. | ||||||||||
| Title: | Critical factors for optimizing the 5-fluorouracil-folinic acid association in cancer chemotherapy. | ||||||||||
| Author: | Etienne, M C|Guillot, T|Milano, G | ||||||||||
| PMID: | 8740793 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Pharmacol. 1996 May 17;51(10):1349-55. | ||||||||||
| Title: | Resistance to tomudex (ZD1694): multifactorial in human breast and colon carcinoma cell lines. | ||||||||||
| Author: | Drake, J C|Allegra, C J|Moran, R G|Johnston, P G | ||||||||||
| PMID: | 8787551 | ||||||||||
| 5. | |||||||||||
| Journal: | Invest New Drugs. 1996;14(3):305-16. | ||||||||||
| Title: | Tomudex (ZD1694): from concept to care, a programme in rational drug discovery. | ||||||||||
| Author: | Jackman, A L|Boyle, F T|Harrap, K R | ||||||||||
| PMID: | 8958186 | ||||||||||
| 6. | |||||||||||
| Journal: | Anticancer Drugs. 1997 Jan;8(1):3-16. | ||||||||||
| Title: | Folate-based thymidylate synthase inhibitors in cancer chemotherapy. | ||||||||||
| Author: | Takemura, Y|Jackman, A L | ||||||||||
| PMID: | 9147608 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Cancer Res. 1997 Apr;3(4):553-7. | ||||||||||
| Title: | Decreased folylpolyglutamate synthetase activity in tumors resistant to fluorouracil-folinic acid treatment: clinical data. | ||||||||||
| Author: | Chazal, M|Cheradame, S|Formento, J L|Francoual, M|Formento, P|Etienne, M C|Francois, E|Richelme, H|Mousseau, M|Letoublon, C|Pezet, D|Cure, H|Seitz, J F|Milano, G | ||||||||||
| PMID: | 9815719 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Cancer Res. 1999 Mar;5(3):643-54. | ||||||||||
| Title: | Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. | ||||||||||
| Author: | van Triest, B|Pinedo, H M|van Hensbergen, Y|Smid, K|Telleman, F|Schoenmakers, P S|van der Wilt, C L|van Laar, J A|Noordhuis, P|Jansen, G|Peters, G J | ||||||||||
| PMID: | 10100718 | ||||||||||
| 9. | |||||||||||
| Journal: | Semin Oncol. 1999 Apr;26(2 Suppl 6):42-7. | ||||||||||
| Title: | Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis. | ||||||||||
| Author: | Mendelsohn, L G|Shih, C|Chen, V J|Habeck, L L|Gates, S B|Shackelford, K A | ||||||||||
| PMID: | 10598554 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncol Res. 1999;11(9):437-45. | ||||||||||
| Title: | Marked variation of thymidylate synthase and folylpolyglutamate synthetase gene expression in human colorectal tumors. | ||||||||||
| Author: | Mini, E|Biondi, C|Morganti, M|Napoli, C|Mazzoni, P|Cianchi, F|Tonelli, F|Cortesini, C|Capaccioli, S|Ficari, F|Quattrone, A|Rossi, S|Mazzei, T | ||||||||||
| PMID: | 10821538 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Cancer. 2000 Sep 15;87(6):771-8. | ||||||||||
| Title: | Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates. | ||||||||||
| Author: | Backus, H H|Pinedo, H M|Wouters, D|Padron, J M|Molders, N|van Der Wilt, C L|van Groeningen, C J|Jansen, G|Peters, G J | ||||||||||
| PMID: | 10956384 | ||||||||||
| 12. | |||||||||||
| Journal: | Biochem Pharmacol. 2003 Aug 1;66(3):431-8. | ||||||||||
| Title: | Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. | ||||||||||
| Author: | Sigmond, Jennifer|Backus, Harold H J|Wouters, Dorine|Temmink, Olaf H|Jansen, Gerrit|Peters, Godefridus J | ||||||||||
| PMID: | 12907242 | ||||||||||
| 13. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):6012-9. | ||||||||||
| Title: | Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. | ||||||||||
| Author: | Odin, Elisabeth|Wettergren, Yvonne|Nilsson, Staffan|Willen, Roger|Carlsson, Goran|Spears, C Paul|Larsson, Lars|Gustavsson, Bengt | ||||||||||
| PMID: | 14676127 | ||||||||||
| 14. | |||||||||||
| Journal: | Gut. 2004 Dec;53(12):1825-31. | ||||||||||
| Title: | Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate. | ||||||||||
| Author: | Sohn, K-J|Smirnakis, F|Moskovitz, D N|Novakovic, P|Yates, Z|Lucock, M|Croxford, R|Kim, Y-I | ||||||||||
| PMID: | 15542523 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Detect Prev. 2005;29(4):348-55. | ||||||||||
| Title: | Low expression of reduced folate carrier-1 and folylpolyglutamate synthase correlates with lack of a deleted in colorectal carcinoma mRNA splice variant in normal-appearing mucosa of colorectal carcinoma patients. | ||||||||||
| Author: | Wettergren, Yvonne|Odin, Elisabeth|Nilsson, Staffan|Willen, Roger|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 16122883 | ||||||||||
| 16. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Apr 1;11(7):2612-9. | ||||||||||
| Title: | Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. | ||||||||||
| Author: | Kidd, Elizabeth A|Yu, Jinsheng|Li, Xia|Shannon, William D|Watson, Mark A|McLeod, Howard L | ||||||||||
| PMID: | 15814641 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Lett. 2006 Oct 28;242(2):168-79. | ||||||||||
| Title: | Tumor quantification of several fluoropyrimidines resistance gene expression with a unique quantitative RT-PCR method. Implications for pretherapeutic determination of tumor resistance phenotype. | ||||||||||
| Author: | Barbado, Maud|Preisser, Laurence|Boisdron-Celle, Michele|Verriele, Veronique|Lorimier, Gerard|Gamelin, Erick|Morel, Alain | ||||||||||
| PMID: | 16387426 | ||||||||||
| 18. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2006 Jan;5(5):344-9. | ||||||||||
| Title: | Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer. | ||||||||||
| Author: | Odin, Elisabeth|Wettergren, Yvonne|Carlsson, Goran|Danenberg, Peter V|Termini, Angelo|Willen, Roger|Gustavsson, Bengt | ||||||||||
| PMID: | 16512993 | ||||||||||
| 19. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2007 Nov;6(10):720-7. | ||||||||||
| Title: | Colorectal carcinomas with microsatellite instability display increased thymidylate synthase gene expression levels. | ||||||||||
| Author: | Odin, Elisabeth|Wettergren, Yvonne|Nilsson, Staffan|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 18039426 | ||||||||||
| 20. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2008 Jan 25;365(4):801-7. | ||||||||||
| Title: | Folylpolyglutamate synthase and gamma-glutamyl hydrolase regulate leucovorin-enhanced 5-fluorouracil anticancer activity. | ||||||||||
| Author: | Sakamoto, Etsuko|Tsukioka, Sayaka|Oie, Shinji|Kobunai, Takashi|Tsujimoto, Hiroaki|Sakamoto, Kazuki|Okayama, Yoshihiro|Sugimoto, Yoshikazu|Oka, Toshinori|Fukushima, Masakazu|Oka, Tatsuzo | ||||||||||
| PMID: | 18035049 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Med. 2008 Jul-Aug;14(7-8):412-21. | ||||||||||
| Title: | p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer. | ||||||||||
| Author: | Wettergren, Yvonne|Odin, Elisabeth|Nilsson, Staffan|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 18418463 | ||||||||||
| 22. | |||||||||||
| Journal: | Am J Clin Nutr. 2008 Oct;88(4):1149-58. | ||||||||||
| Title: | Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. | ||||||||||
| Author: | DeVos, Lauren|Chanson, Aurelie|Liu, Zhenhua|Ciappio, Eric D|Parnell, Laurence D|Mason, Joel B|Tucker, Katherine L|Crott, Jimmy W | ||||||||||
| PMID: | 18842806 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Mar;65(4):735-42. | ||||||||||
| Title: | Molecular determinants of folate levels after leucovorin administration in colorectal cancer. | ||||||||||
| Author: | Sadahiro, Sotaro|Suzuki, Toshiyuki|Maeda, Yuji|Tanaka, Akira|Ogoshi, Kyoji|Kamijo, Akemi|Murayama, Chieko|Tsukioka, Sayaka|Sakamoto, Etsuko|Fukui, Yousuke|Oka, Toshinori | ||||||||||
| PMID: | 19636555 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Aug;66(3):547-58. | ||||||||||
| Title: | Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines. | ||||||||||
| Author: | Nannizzi, Sara|Veal, Gareth J|Giovannetti, Elisa|Mey, Valentina|Ricciardi, Simona|Ottley, Christopher J|Del Tacca, Mario|Danesi, Romano | ||||||||||
| PMID: | 20020129 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Causes Control. 2010 Apr;21(4):597-608. | ||||||||||
| Title: | Genes involved with folate uptake and distribution and their association with colorectal cancer risk. | ||||||||||
| Author: | Figueiredo, Jane C|Levine, A Joan|Lee, Won H|Conti, David V|Poynter, Jenny N|Campbell, Peter T|Duggan, David|Lewinger, Juan Pablo|Martinez, Maria Elena|Ulrich, Cornelia M|Newcomb, Polly|Potter, John|Limburg, Paul J|Hopper, John|Jenkins, Mark A|Le Marchand | ||||||||||
| PMID: | 20037791 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncol Rep. 2011 May;25(5):1407-12. | ||||||||||
| Title: | In vivo evidence for a significant role of folylpolyglutamate synthase in combined chemotherapy with oral fluoropyrimidine, UFT or S-1, and leucovorin. | ||||||||||
| Author: | Tsukioka, Sayaka|Sakamoto, Etsuko|Tsujimoto, Hiroaki|Nakagawa, Fumio|Saito, Hitoshi|Uchida, Junji|Kiniwa, Mamoru|Fukushima, Masakazu | ||||||||||
| PMID: | 21380490 | ||||||||||
| 27. | |||||||||||
| Journal: | J Oncol. 2013;2013:386906. | ||||||||||
| Title: | Analysis of the mRNA expression of chemotherapy-related genes in colorectal carcinoma using the danenberg tumor profile method. | ||||||||||
| Author: | Sasaki, Shin|Watanabe, Toshiyuki|Nakayama, Hiroshi | ||||||||||
| PMID: | 23577026 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Mol Med. 2016 Feb;37(2):319-28. | ||||||||||
| Title: | Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis. | ||||||||||
| Author: | Shimamoto, Yuji|Nukatsuka, Mamoru|Takechi, Teiji|Fukushima, Masakazu | ||||||||||
| PMID: | 26676887 | ||||||||||
| 29. | |||||||||||
| Journal: | Intest Res. 2016 Apr;14(2):172-7. | ||||||||||
| Title: | Do we need colonoscopy verification in patients with fundic gland polyp? | ||||||||||
| Author: | Lee, Hee Sook|Choi, Younjeong|Jung, Ja Young|Sung, Young-Jun|Ahn, Dong Won|Jeong, Ji Bong|Kim, Byeong Gwan|Lee, Kook Lae|Koh, Seong-Joon|Kim, Ji Won | ||||||||||
| PMID: | 27175118 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2018 Sep 29. pii: 10.1007/s00280-018-3690-9. | ||||||||||
| Title: | Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal cancer. | ||||||||||
| Author: | Taflin, Helena|Odin, Elisabeth|Derwinger, Kristoffer|Carlsson, Goran|Gustavsson, Bengt|Wettergren, Yvonne | ||||||||||
| PMID: | 30269276 | ||||||||||