Primary Site >> Colorectal Cancer
Gene >> FOXO3
| 1. | |||||||||||
| Journal: | Mol Cell Biol. 2002 Apr;22(7):2025-36. | ||||||||||
| Title: | Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. | ||||||||||
| Author: | Kops, Geert J P L|Medema, Rene H|Glassford, Janet|Essers, Marieke A G|Dijkers, Pascale F|Coffer, Paul J|Lam, Eric W-F|Burgering, Boudewijn M T | ||||||||||
| PMID: | 11884591 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Oncol. 2004 May;24(5):1279-88. | ||||||||||
| Title: | Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil. | ||||||||||
| Author: | de Angelis, Paula M|Fjell, Bjorg|Kravik, Katherine L|Haug, Terje|Tunheim, Siv H|Reichelt, Wenche|Beigi, Marzieh|Clausen, Ole Petter|Galteland, Eivind|Stokke, Trond | ||||||||||
| PMID: | 15067352 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2004 Oct 29;279(44):45721-7. Epub 2004 Aug 18. | ||||||||||
| Title: | MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. | ||||||||||
| Author: | Yin, Li|Huang, Lei|Kufe, Donald | ||||||||||
| PMID: | 15322085 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Cell. 2005 Jun;7(6):561-73. | ||||||||||
| Title: | Mutant PIK3CA promotes cell growth and invasion of human cancer cells. | ||||||||||
| Author: | Samuels, Yardena|Diaz, Luis A Jr|Schmidt-Kittler, Oleg|Cummins, Jordan M|Delong, Laura|Cheong, Ian|Rago, Carlo|Huso, David L|Lengauer, Christoph|Kinzler, Kenneth W|Vogelstein, Bert|Velculescu, Victor E | ||||||||||
| PMID: | 15950905 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cell Biol. 2007 Jul;27(13):4917-30. Epub 2007 Apr 23. | ||||||||||
| Title: | Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression. | ||||||||||
| Author: | Delpuech, Oona|Griffiths, Beatrice|East, Philip|Essafi, Abdelkader|Lam, Eric W-F|Burgering, Boudewijn|Downward, Julian|Schulze, Almut | ||||||||||
| PMID: | 17452451 | ||||||||||
| 6. | |||||||||||
| Journal: | Genome Biol. 2007;8(7):R131. | ||||||||||
| Title: | Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. | ||||||||||
| Author: | Kaiser, Sergio|Park, Young-Kyu|Franklin, Jeffrey L|Halberg, Richard B|Yu, Ming|Jessen, Walter J|Freudenberg, Johannes|Chen, Xiaodi|Haigis, Kevin|Jegga, Anil G|Kong, Sue|Sakthivel, Bhuvaneswari|Xu, Huan|Reichling, Timothy|Azhar, Mohammad|Boivin, Gregory P| | ||||||||||
| PMID: | 17615082 | ||||||||||
| 7. | |||||||||||
| Journal: | J Biol Chem. 2008 Jul 11;283(28):19201-10. | ||||||||||
| Title: | Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1. | ||||||||||
| Author: | Dehner, Manuel|Hadjihannas, Michel|Weiske, Jorg|Huber, Otmar|Behrens, Jurgen | ||||||||||
| PMID: | 18487207 | ||||||||||
| 8. | |||||||||||
| Journal: | Radiat Res. 2008 Aug;170(2):184-91. | ||||||||||
| Title: | G0 cell cycle arrest alone is insufficient for enabling the repair of ionizing radiation-induced potentially lethal damage. | ||||||||||
| Author: | van Bree, Chris|Rodermond, Hans M|ten Cate, Rosemarie|de Vos, Judith|Stalpers, Lukas J A|Haveman, Jaap|Medema, Jan Paul|Franken, Nicolaas A P | ||||||||||
| PMID: | 18666809 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2008 Sep 15;68(18):7270-7. | ||||||||||
| Title: | LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. | ||||||||||
| Author: | Zhong, Diansheng|Liu, Xiuju|Khuri, Fadlo R|Sun, Shi-Yong|Vertino, Paula M|Zhou, Wei | ||||||||||
| PMID: | 18794113 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Ther. 2008 Oct;7(10):3237-46. | ||||||||||
| Title: | FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells. | ||||||||||
| Author: | Fernandez de Mattos, Silvia|Villalonga, Priam|Clardy, Jon|Lam, Eric W-F | ||||||||||
| PMID: | 18852127 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Biol (Mosk). 2008 Nov-Dec;42(6):1004-11. | ||||||||||
| Title: | [A lentivirus vector based assay system for quantitative detection of intracellular translocations of recombinant proteins]. | ||||||||||
| Author: | Chumakov, S P|Il'inskaia, G V|Kravchenko, Iu E|Frolova, E I|Prasolov, V S|Chumakov, P M | ||||||||||
| PMID: | 19140320 | ||||||||||
| 12. | |||||||||||
| Journal: | Leuk Res. 2009 Nov;33(11):1530-8. | ||||||||||
| Title: | Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells. | ||||||||||
| Author: | Akao, Yukihiro|Nakagawa, Yoshihito|Iio, Akio|Naoe, Tomoki | ||||||||||
| PMID: | 19464056 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncogene. 2009 Dec 17;28(50):4421-33. | ||||||||||
| Title: | A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. | ||||||||||
| Author: | Mamidipudi, V|Cartwright, C A | ||||||||||
| PMID: | 19767770 | ||||||||||
| 14. | |||||||||||
| Journal: | Biomed Environ Sci. 2009 Jun;22(3):244-52. | ||||||||||
| Title: | Role of prosurvival molecules in the action of lidamycin toward human tumor cells. | ||||||||||
| Author: | Yang, A-Jing|Shi, Wei-Wei|Li, Yong|Wang, Zhen|Shao, Rong-Guang|Li, Dian-Dong|He, Qi-Yang | ||||||||||
| PMID: | 19725468 | ||||||||||
| 15. | |||||||||||
| Journal: | Autophagy. 2009 Oct;5(7):1030-3. Epub 2009 Oct 12. | ||||||||||
| Title: | Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism. | ||||||||||
| Author: | Chiacchiera, Fulvio|Simone, Cristiano | ||||||||||
| PMID: | 19587525 | ||||||||||
| 16. | |||||||||||
| Journal: | IUBMB Life. 2009 Jul;61(7):768-76. | ||||||||||
| Title: | Relative resistance of SGK1 knockout mice against chemical carcinogenesis. | ||||||||||
| Author: | Nasir, Omaima|Wang, Kan|Foller, Michael|Gu, Shuchen|Bhandaru, Madhuri|Ackermann, Teresa F|Boini, Krishna M|Mack, Andreas|Klingel, Karin|Amato, Rosario|Perrotti, Nicola|Kuhl, Dietmar|Behrens, Jurgen|Stournaras, Christos|Lang, Florian | ||||||||||
| PMID: | 19548318 | ||||||||||
| 17. | |||||||||||
| Journal: | Cell Death Differ. 2009 Sep;16(9):1203-14. | ||||||||||
| Title: | p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. | ||||||||||
| Author: | Chiacchiera, F|Matrone, A|Ferrari, E|Ingravallo, G|Lo Sasso, G|Murzilli, S|Petruzzelli, M|Salvatore, L|Moschetta, A|Simone, C | ||||||||||
| PMID: | 19343039 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Gynecol Cancer. 2010 Feb;20(2):203-11. | ||||||||||
| Title: | p38alpha is required for ovarian cancer cell metabolism and survival. | ||||||||||
| Author: | Matrone, Antonio|Grossi, Valentina|Chiacchiera, Fulvio|Fina, Emanuela|Cappellari, Marianna|Caringella, Anna Maria|Di Naro, Edoardo|Loverro, Giuseppe|Simone, Cristiano | ||||||||||
| PMID: | 20169663 | ||||||||||
| 19. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2010 Oct;42(10):1571-5. | ||||||||||
| Title: | Colorectal carcinoma cells--regulation of survival and growth by SGK1. | ||||||||||
| Author: | Lang, Florian|Perrotti, Nicola|Stournaras, Christos | ||||||||||
| PMID: | 20541034 | ||||||||||
| 20. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72. | ||||||||||
| Title: | Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells. | ||||||||||
| Author: | Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Roy, Hemant|Wali, Ramesh|Joshi, Suhasini|Savkovic, Suzana D | ||||||||||
| PMID: | 21109589 | ||||||||||
| 21. | |||||||||||
| Journal: | BMC Cancer. 2011 Jun 3;11:219. | ||||||||||
| Title: | Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity. | ||||||||||
| Author: | Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Savkovic, Suzana D | ||||||||||
| PMID: | 21639915 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Lett. 2012 Nov 1;324(1):98-108. | ||||||||||
| Title: | Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models. | ||||||||||
| Author: | Chiacchiera, Fulvio|Grossi, Valentina|Cappellari, Marianna|Peserico, Alessia|Simonatto, Marta|Germani, Aldo|Russo, Silvana|Moyer, Mary P|Resta, Nicoletta|Murzilli, Stefania|Simone, Cristiano | ||||||||||
| PMID: | 22579651 | ||||||||||
| 23. | |||||||||||
| Journal: | World J Biol Chem. 2012 Sep 26;3(9):175-9. | ||||||||||
| Title: | Nuclear accumulation of beta-catenin and forkhead box O3a in colon cancer: Dangerous liaison. | ||||||||||
| Author: | Link, Wolfgang | ||||||||||
| PMID: | 23024836 | ||||||||||
| 24. | |||||||||||
| Journal: | Nat Med. 2012 Jun 6;18(6):854-6. | ||||||||||
| Title: | FOXO3a and beta-catenin co-localization: double trouble in colon cancer? | ||||||||||
| Author: | Yan, Yibing|Lackner, Mark R | ||||||||||
| PMID: | 22673992 | ||||||||||
| 25. | |||||||||||
| Journal: | Antioxid Redox Signal. 2013 Apr 10;18(11):1249-62. | ||||||||||
| Title: | Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a. | ||||||||||
| Author: | Saxena, Ashish|Tammali, Ravinder|Ramana, Kota V|Srivastava, Satish K | ||||||||||
| PMID: | 22978663 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Res. 2013 Nov 1;73(21):6435-47. | ||||||||||
| Title: | miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance. | ||||||||||
| Author: | Zhang, Lei|Pickard, Karen|Jenei, Veronika|Bullock, Marc D|Bruce, Amanda|Mitter, Richard|Kelly, Gavin|Paraskeva, Christos|Strefford, John|Primrose, John|Thomas, Gareth J|Packham, Graham|Mirnezami, Alex H | ||||||||||
| PMID: | 23950211 | ||||||||||
| 27. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Sep 1;19(17):4662-72. | ||||||||||
| Title: | microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2. | ||||||||||
| Author: | Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing | ||||||||||
| PMID: | 23846336 | ||||||||||
| 28. | |||||||||||
| Journal: | Br J Cancer. 2013 Jul 23;109(2):297-8. | ||||||||||
| Title: | Decreased FOXO3 within advanced human colon cancer: implications of tumour suppressor function. | ||||||||||
| Author: | Savkovic, S D | ||||||||||
| PMID: | 23828519 | ||||||||||
| 29. | |||||||||||
| Journal: | Br J Cancer. 2013 Jul 23;109(2):387-94. | ||||||||||
| Title: | FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role. | ||||||||||
| Author: | Bullock, M D|Bruce, A|Sreekumar, R|Curtis, N|Cheung, T|Reading, I|Primrose, J N|Ottensmeier, C|Packham, G K|Thomas, G|Mirnezami, A H | ||||||||||
| PMID: | 23828518 | ||||||||||
| 30. | |||||||||||
| Journal: | Free Radic Biol Med. 2013 Oct;63:280-90. | ||||||||||
| Title: | Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors. | ||||||||||
| Author: | Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K | ||||||||||
| PMID: | 23732517 | ||||||||||
| 31. | |||||||||||
| Journal: | J Amino Acids. 2013;2013:509056. | ||||||||||
| Title: | DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment. | ||||||||||
| Author: | Gomez-Monterrey, Isabel|Campiglia, Pietro|Scognamiglio, Ilaria|Vanacore, Daniela|Dicitore, Alessandra|Lombardi, Angela|Caraglia, Michele|Novellino, Ettore|Stiuso, Paola | ||||||||||
| PMID: | 23710334 | ||||||||||
| 32. | |||||||||||
| Journal: | J Biol Chem. 2013 Jun 7;288(23):16274-81. | ||||||||||
| Title: | FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density. | ||||||||||
| Author: | Qi, Wentao|Fitchev, Philip S|Cornwell, Mona L|Greenberg, Jordan|Cabe, Maleen|Weber, Christopher R|Roy, Hemant K|Crawford, Susan E|Savkovic, Suzana D | ||||||||||
| PMID: | 23603907 | ||||||||||
| 33. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):205-211. | ||||||||||
| Title: | Remarkably reduced expression of FoxO3a in metaplastic colorectum, primary colorectal cancer and liver metastasis. | ||||||||||
| Author: | He, Le-Ya|Wei, Xin|Du, Lei|Liu, Lu|Xu, Feng|Min, Jiang|Li, Chuan|Tao, De-Ding|Chen, Quan|Hu, Jun-Bo|Gong, Jian-Ping | ||||||||||
| PMID: | 23592131 | ||||||||||
| 34. | |||||||||||
| Journal: | Int J Cancer. 2013 Aug 15;133(4):984-96. | ||||||||||
| Title: | Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer. | ||||||||||
| Author: | Kim, Areumnuri|Lee, Jung-Eun|Lee, Seung-Sook|Kim, Cherin|Lee, Sun-Joo|Jang, Won-Suk|Park, Sunhoo | ||||||||||
| PMID: | 23475782 | ||||||||||
| 35. | |||||||||||
| Journal: | Int J Mol Sci. 2013 Jan 31;14(2):2980-95. | ||||||||||
| Title: | Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions. | ||||||||||
| Author: | Zhang, Zhiyu|Du, Guang-Jian|Wang, Chong-Zhi|Wen, Xiao-Dong|Calway, Tyler|Li, Zejuan|He, Tong-Chuan|Du, Wei|Bissonnette, Marc|Musch, Mark W|Chang, Eugene B|Yuan, Chun-Su | ||||||||||
| PMID: | 23434653 | ||||||||||
| 36. | |||||||||||
| Journal: | Cell Death Dis. 2013 Feb 7;4:e481. | ||||||||||
| Title: | PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells. | ||||||||||
| Author: | Luo, H|Yang, Y|Duan, J|Wu, P|Jiang, Q|Xu, C | ||||||||||
| PMID: | 23392169 | ||||||||||
| 37. | |||||||||||
| Journal: | BMC Cancer. 2014 Dec 24;14:997. | ||||||||||
| Title: | Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia. | ||||||||||
| Author: | Judge, Sarah M|Wu, Chia-Ling|Beharry, Adam W|Roberts, Brandon M|Ferreira, Leonardo F|Kandarian, Susan C|Judge, Andrew R | ||||||||||
| PMID: | 25539728 | ||||||||||
| 38. | |||||||||||
| Journal: | Sci Signal. 2014 Nov 11;7(351):ra107. | ||||||||||
| Title: | Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR. | ||||||||||
| Author: | Belmont, Peter J|Jiang, Ping|McKee, Trevor D|Xie, Tao|Isaacson, Jason|Baryla, Nicole E|Roper, Jatin|Sinnamon, Mark J|Lee, Nathan V|Kan, Julie L C|Guicherit, Oivin|Wouters, Bradly G|O'Brien, Catherine A|Shields, David|Olson, Peter|VanArsdale, Todd|Weinrich | ||||||||||
| PMID: | 25389372 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Lett. 2014 Oct 10;353(1):87-94. | ||||||||||
| Title: | FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways. | ||||||||||
| Author: | Cui, Yan-Mei|Jiang, Dan|Zhang, Shi-Hong|Wu, Ping|Ye, Ya-Ping|Chen, Cui-Min|Tang, Na|Liang, Li|Li, Ting-Ting|Qi, Lu|Wang, Shu-Yang|Jiao, Hong-Li|Lin, Jie|Ding, Yan-Qing|Liao, Wen-Ting | ||||||||||
| PMID: | 25069037 | ||||||||||
| 40. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2014 Apr;36(4):257-62. | ||||||||||
| Title: | [Changes of expression of miR-155 in colitis-associated colonic carcinogenesis]. | ||||||||||
| Author: | Li, Weiwei|Han, Wenxiao|Zhao, Xinhua|Wang, Hongying | ||||||||||
| PMID: | 24989910 | ||||||||||
| 41. | |||||||||||
| Journal: | Food Funct. 2014 Aug;5(8):1909-14. | ||||||||||
| Title: | Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation. | ||||||||||
| Author: | Sun, Lijuan|Luo, Cheng|Liu, Jiankang | ||||||||||
| PMID: | 24953710 | ||||||||||
| 42. | |||||||||||
| Journal: | J Clin Endocrinol Metab. 2014 Jul;99(7):E1163-72. | ||||||||||
| Title: | ZIC1 is a putative tumor suppressor in thyroid cancer by modulating major signaling pathways and transcription factor FOXO3a. | ||||||||||
| Author: | Qiang, Wei|Zhao, Yuan|Yang, Qi|Liu, Wei|Guan, Haixia|Lv, Siqing|Ji, Meiju|Shi, Bingyin|Hou, Peng | ||||||||||
| PMID: | 24684457 | ||||||||||
| 43. | |||||||||||
| Journal: | Int J Mol Med. 2014 Mar;33(3):581-8. | ||||||||||
| Title: | Revealing the molecular mechanism of colorectal cancer by establishing LGALS3-related protein-protein interaction network and identifying signaling pathways. | ||||||||||
| Author: | Han, Lu|Wu, Zhixiong|Zhao, Qicheng | ||||||||||
| PMID: | 24398765 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Lett. 2014 Mar 1;344(1):110-8. | ||||||||||
| Title: | Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A. | ||||||||||
| Author: | Germani, Aldo|Matrone, Antonio|Grossi, Valentina|Peserico, Alessia|Sanese, Paola|Liuzzi, Micaela|Palermo, Rocco|Murzilli, Stefania|Campese, Antonio Francesco|Ingravallo, Giuseppe|Canettieri, Gianluca|Tezil, Tugsan|Simone, Cristiano | ||||||||||
| PMID: | 24215867 | ||||||||||
| 45. | |||||||||||
| Journal: | Oncogene. 2014 Apr 10;33(15):1975-85. | ||||||||||
| Title: | SPROUTY2 is a beta-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. | ||||||||||
| Author: | Ordonez-Moran, P|Irmisch, A|Barbachano, A|Chicote, I|Tenbaum, S|Landolfi, S|Tabernero, J|Huelsken, J|Munoz, A|Palmer, H G | ||||||||||
| PMID: | 23624922 | ||||||||||
| 46. | |||||||||||
| Journal: | Int J Oncol. 2014 Aug;45(2):587-94. | ||||||||||
| Title: | Differential expression of miRNAs in colon cancer between African and Caucasian Americans: implications for cancer racial health disparities. | ||||||||||
| Author: | Li, Ellen|Ji, Ping|Ouyang, Nengtai|Zhang, Yuanhao|Wang, Xin Yu|Rubin, Deborah C|Davidson, Nicholas O|Bergamaschi, Roberto|Shroyer, Kenneth R|Burke, Stephanie|Zhu, Wei|Williams, Jennie L | ||||||||||
| PMID: | 24865442 | ||||||||||
| 47. | |||||||||||
| Journal: | Mol Med Rep. 2015 Feb;11(2):1200-6. | ||||||||||
| Title: | MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a. | ||||||||||
| Author: | Gao, Feng|Wang, Wenhui | ||||||||||
| PMID: | 25369914 | ||||||||||
| 48. | |||||||||||
| Journal: | Cancer Lett. 2015 Apr 1;359(1):47-56. | ||||||||||
| Title: | Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer. | ||||||||||
| Author: | Qazi, Asif Khurshid|Hussain, Aashiq|Khan, Saima|Aga, Mushtaq A|Behl, Akanksha|Ali, Shakir|Singh, Shashank Kumar|Taneja, Subhash Chandra|Shah, Bhahwal Ali|Saxena, Ajit Kumar|Mondhe, Dilip Manikrao|Hamid, Abid | ||||||||||
| PMID: | 25554016 | ||||||||||
| 49. | |||||||||||
| Journal: | Oncogene. 2015 Nov 19;34(47):5843-56. | ||||||||||
| Title: | The DEAD box protein p68: a crucial regulator of AKT/FOXO3a signaling axis in oncogenesis. | ||||||||||
| Author: | Sarkar, M|Khare, V|Guturi, K K N|Das, N|Ghosh, M K | ||||||||||
| PMID: | 25745998 | ||||||||||
| 50. | |||||||||||
| Journal: | Exp Cell Res. 2015 Oct 15;338(1):10-21. | ||||||||||
| Title: | Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells. | ||||||||||
| Author: | Coskun, Deniz|Obakan, Pinar|Arisan, Elif Damla|Coker-Gurkan, Ajda|Palavan-Unsal, Narcin | ||||||||||
| PMID: | 26318418 | ||||||||||
| 51. | |||||||||||
| Journal: | Am J Transl Res. 2015 Dec 15;7(12):2775-85. eCollection 2015. | ||||||||||
| Title: | miR-451 regulates FoxO3 nuclear accumulation through Ywhaz in human colorectal cancer. | ||||||||||
| Author: | Li, Yaoyao|Wang, Jijun|Dai, Xiaorong|Zhou, Zhengbin|Liu, Jing|Zhang, Yu|Li, Yan|Hou, Yaying|Pang, Lei|Wang, Xiaohong|Wang, Chenhai|Hao, Zhenfeng|Zhang, Yanqing|Jiang, Jixin|Cheng, Hongwei|Yu, Duonan | ||||||||||
| PMID: | 26885274 | ||||||||||
| 52. | |||||||||||
| Journal: | Oncogene. 2016 Sep 1;35(35):4611-22. | ||||||||||
| Title: | Inhibition of colon cancer growth by docosahexaenoic acid involves autocrine production of TNFalpha. | ||||||||||
| Author: | Fluckiger, A|Dumont, A|Derangere, V|Rebe, C|de Rosny, C|Causse, S|Thomas, C|Apetoh, L|Hichami, A|Ghiringhelli, F|Rialland, M | ||||||||||
| PMID: | 26853468 | ||||||||||
| 53. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 6;7(49):80888-80900. | ||||||||||
| Title: | FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc. | ||||||||||
| Author: | Yu, Yiyi|Guo, Mengzhou|Wei, Ye|Yu, Shan|Li, Hong|Wang, Yan|Xu, Xiaojing|Cui, Yuehong|Tian, Jiawen|Liang, Li|Peng, Ke|Liu, Tianshu | ||||||||||
| PMID: | 27825133 | ||||||||||
| 54. | |||||||||||
| Journal: | Br J Cancer. 2016 Nov 8;115(10):1223-1233. | ||||||||||
| Title: | FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer. | ||||||||||
| Author: | Marzi, L|Combes, E|Vie, N|Ayrolles-Torro, A|Tosi, D|Desigaud, D|Perez-Gracia, E|Larbouret, C|Montagut, C|Iglesias, M|Jarlier, M|Denis, V|Linares, L K|Lam, E W-F|Martineau, P|Del Rio, M|Gongora, C | ||||||||||
| PMID: | 27685445 | ||||||||||
| 55. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Sep 9;478(1):18-24. | ||||||||||
| Title: | Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells. | ||||||||||
| Author: | Park, Seong-Yeol|Bae, Young-Seuk | ||||||||||
| PMID: | 27470586 | ||||||||||
| 56. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):49848-49858. | ||||||||||
| Title: | Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization. | ||||||||||
| Author: | Wang, Hao|Huang, Cheng|Zhao, Liang|Zhang, Huan|Yang, Jing Mo|Luo, Peng|Zhan, Bing-Xiang|Pan, Qing|Li, Jun|Wang, Bao-Long | ||||||||||
| PMID: | 27409663 | ||||||||||
| 57. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2016 Jul;20(7):771-82. | ||||||||||
| Title: | An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A). | ||||||||||
| Author: | Fu, Qi|Du, Yong|Yang, Chun|Zhang, Dong|Zhang, Ningmei|Liu, Xiaoming|Cho, William C|Yang, Yinxue | ||||||||||
| PMID: | 27167185 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncol Rep. 2016 Jun;35(6):3363-70. | ||||||||||
| Title: | Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways. | ||||||||||
| Author: | Liu, Jiming|Li, Qiang|Liu, Zhilong|Lin, Liuming|Zhang, Xiangqiang|Cao, Mingrong|Jiang, Jianwei | ||||||||||
| PMID: | 27004568 | ||||||||||
| 59. | |||||||||||
| Journal: | Sci Rep. 2016 Feb 26;6:22090. | ||||||||||
| Title: | PS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway. | ||||||||||
| Author: | Yang, Zhao|Liu, Shengwu|Zhu, Mingao|Zhang, Hong|Wang, Ji|Xu, Qian|Lin, Kaisu|Zhou, Xiumin|Tao, Min|Li, Chong|Zhu, Hong | ||||||||||
| PMID: | 26915315 | ||||||||||
| 60. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Feb 19;470(4):851-6. | ||||||||||
| Title: | Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells. | ||||||||||
| Author: | Mizutani, Naoki|Omori, Yukari|Kawamoto, Yoshiyuki|Sobue, Sayaka|Ichihara, Masatoshi|Suzuki, Motoshi|Kyogashima, Mamoru|Nakamura, Mitsuhiro|Tamiya-Koizumi, Keiko|Nozawa, Yoshinori|Murate, Takashi | ||||||||||
| PMID: | 26809095 | ||||||||||
| 61. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6. | ||||||||||
| Title: | Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. | ||||||||||
| Author: | Penrose, Harrison|Heller, Sandra|Cable, Chloe|Makboul, Rania|Chadalawada, Gita|Chen, Ying|Crawford, Susan E|Savkovic, Suzana D | ||||||||||
| PMID: | 26657850 | ||||||||||
| 62. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Feb 1;22(3):644-56. | ||||||||||
| Title: | Tankyrase Inhibition Blocks Wnt/beta-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer. | ||||||||||
| Author: | Arques, Oriol|Chicote, Irene|Puig, Isabel|Tenbaum, Stephan P|Argiles, Guillem|Dienstmann, Rodrigo|Fernandez, Natalia|Caratu, Ginevra|Matito, Judit|Silberschmidt, Daniel|Rodon, Jordi|Landolfi, Stefania|Prat, Aleix|Espin, Eloy|Charco, Ramon|Nuciforo, Paolo| | ||||||||||
| PMID: | 26224873 | ||||||||||
| 63. | |||||||||||
| Journal: | Am J Pathol. 2017 Feb;187(2):377-389. | ||||||||||
| Title: | cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium. | ||||||||||
| Author: | Wang, Rui|Islam, Bianca N|Bridges, Allison|Sharman, Sarah K|Hu, Muhan|Hou, Yali|Somanath, Payaningal R|Venable, Laine|Singh, Nagendra|Kim, Sangmi|Sridhar, Subbaramiah|Hofmann, Franz|Browning, Darren D | ||||||||||
| PMID: | 27998725 | ||||||||||
| 64. | |||||||||||
| Journal: | Ann Surg Oncol. 2017 Dec;24(13):4051-4058. | ||||||||||
| Title: | Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival. | ||||||||||
| Author: | Clarke, Callisia N|Lee, Michael S|Wei, Wei|Manyam, Ganiraju|Jiang, Zhi-Qin|Lu, Yiling|Morris, Jeffrey|Broom, Bradley|Menter, David|Vilar-Sanchez, Eduardo|Raghav, Kanwal|Eng, Cathy|Chang, George J|Simon, Iris|Bernards, Rene|Overman, Michael|Mills, Gordon B | ||||||||||
| PMID: | 28936799 | ||||||||||
| 65. | |||||||||||
| Journal: | Jpn J Radiol. 2017 Nov;35(11):664-672. | ||||||||||
| Title: | Involvement of miR-155/FOXO3a and miR-222/PTEN in acquired radioresistance of colorectal cancer cell line. | ||||||||||
| Author: | Khoshinani, Hamed Manoochehri|Afshar, Saeid|Pashaki, Abdolazim Sedighi|Mahdavinezhad, Ali|Nikzad, Safora|Najafi, Rezvan|Amini, Razieh|Gholami, Mohammad Hadi|Khoshghadam, Alireza|Saidijam, Massoud | ||||||||||
| PMID: | 28879560 | ||||||||||
| 66. | |||||||||||
| Journal: | Mol Med Rep. 2017 Oct;16(4):5592-5598. | ||||||||||
| Title: | XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelialmesenchymal transition. | ||||||||||
| Author: | Shen, Jiancheng|Jin, Chang'e|Liu, Yonglin|Rao, Heping|Liu, Jinrong|Li, Jie | ||||||||||
| PMID: | 28849225 | ||||||||||
| 67. | |||||||||||
| Journal: | Sci Rep. 2017 Jul 20;7(1):5952. | ||||||||||
| Title: | PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated Microgravity. | ||||||||||
| Author: | Arun, Raj Pranap|Sivanesan, Divya|Vidyasekar, Prasanna|Verma, Rama Shanker | ||||||||||
| PMID: | 28729699 | ||||||||||
| 68. | |||||||||||
| Journal: | Cell Cycle. 2017 Jul 3;16(13):1243-1251. | ||||||||||
| Title: | NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer. | ||||||||||
| Author: | Karki, Rajendra|Malireddi, R K Subbarao|Zhu, Qifan|Kanneganti, Thirumala-Devi | ||||||||||
| PMID: | 28598238 | ||||||||||
| 69. | |||||||||||
| Journal: | Mol Cancer. 2017 May 26;16(1):96. | ||||||||||
| Title: | MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway. | ||||||||||
| Author: | Liang, Zhen|Wang, Xiao|Xu, Xin|Xie, Bo|Ji, Alin|Meng, Shuai|Li, Shiqi|Zhu, Yi|Wu, Jian|Hu, Zhenghui|Lin, Yiwei|Zheng, Xiangyi|Xie, Liping|Liu, Ben | ||||||||||
| PMID: | 28549468 | ||||||||||
| 70. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1392-1402. | ||||||||||
| Title: | Assessment of histone tail modifications and transcriptional profiling during colon cancer progression reveals a global decrease in H3K4me3 activity. | ||||||||||
| Author: | Triff, Karen|McLean, Mathew W|Konganti, Kranti|Pang, Jiahui|Callaway, Evelyn|Zhou, Beiyan|Ivanov, Ivan|Chapkin, Robert S | ||||||||||
| PMID: | 28315775 | ||||||||||
| 71. | |||||||||||
| Journal: | Cell Death Dis. 2017 Jan 5;8(1):e2536. | ||||||||||
| Title: | REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival. | ||||||||||
| Author: | Song, Kwon-Ho|Woo, Seon Rang|Chung, Joon-Yong|Lee, Hyo-Jung|Oh, Se Jin|Hong, Soon-Oh|Shim, Jaegal|Kim, Yong Nyun|Rho, Seung Bae|Hong, Seung-Mo|Cho, Hanbyoul|Hibi, Masahiko|Bae, Dong-Jun|Kim, Sang-Yeob|Kim, Min Gyu|Kim, Tae Woo|Bae, Young-Ki | ||||||||||
| PMID: | 28055019 | ||||||||||
| 72. | |||||||||||
| Journal: | FASEB J. 2017 Apr;31(4):1516-1530. | ||||||||||
| Title: | Inflammatory hypoxia induces syndecan-2 expression through IL-1beta-mediated FOXO3a activation in colonic epithelia. | ||||||||||
| Author: | Choi, Sojoong|Chung, Heesung|Hong, Heejeong|Kim, So Yeon|Kim, Seong-Eun|Seoh, Ju-Young|Moon, Chang Mo|Yang, Eun Gyeong|Oh, Eok-Soo | ||||||||||
| PMID: | 28031321 | ||||||||||
| 73. | |||||||||||
| Journal: | Int J Oncol. 2018 Jan;52(1):211-218. | ||||||||||
| Title: | Simvastatin enhances the radiosensitivity of p53deficient cells via inhibition of mouse double minute 2 homolog. | ||||||||||
| Author: | Lee, Ji Young|Kim, Mi-Sook|Ju, Jae Eun|Lee, Mi So|Chung, Namhyun|Jeong, Youn Kyoung | ||||||||||
| PMID: | 29115437 | ||||||||||
| 74. | |||||||||||
| Journal: | Biomed Pharmacother. 2018 Feb;98:286-296. | ||||||||||
| Title: | Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1. | ||||||||||
| Author: | Liu, Tianyou|Yu, Tao|Hu, Haiying|He, Keping | ||||||||||
| PMID: | 29274585 | ||||||||||
| 75. | |||||||||||
| Journal: | Genome Med. 2018 Jan 4;10(1):2. | ||||||||||
| Title: | Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells. | ||||||||||
| Author: | Kundu, Snehangshu|Ali, Muhammad Akhtar|Handin, Niklas|Padhan, Narendra|Larsson, Jimmy|Karoutsou, Maria|Ban, Kenneth|Wisniewski, Jacek R|Artursson, Per|He, Liqun|Hellstrom, Mats|Sjoblom, Tobias | ||||||||||
| PMID: | 29301589 | ||||||||||
| 76. | |||||||||||
| Journal: | Oncol Lett. 2018 Apr;15(4):4781-4788. | ||||||||||
| Title: | MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3. | ||||||||||
| Author: | Gao, Yuewen|Liu, Zhaoyan|Ding, Zhaohong|Hou, Shicai|Li, Jun|Jiang, Kehua | ||||||||||
| PMID: | 29552117 | ||||||||||
| 77. | |||||||||||
| Journal: | Oncol Rep. 2018 May;39(5):2235-2242. | ||||||||||
| Title: | SP1 upregulated FoxO3a promotes tumor progression in colorectal cancer. | ||||||||||
| Author: | Yu, Yiyi|Peng, Ke|Li, Hong|Zhuang, Rongyuan|Wang, Yan|Li, Wei|Yu, Shan|Liang, Li|Xu, Xiaojing|Liu, Tianshu | ||||||||||
| PMID: | 29565456 | ||||||||||
| 78. | |||||||||||
| Journal: | Phytomedicine. 2018 Mar 15;42:164-171. | ||||||||||
| Title: | Pristimerin, a naturally occurring triterpenoid, attenuates tumorigenesis in experimental colitis-associated colon cancer. | ||||||||||
| Author: | Park, Ju-Hyung|Kim, Jin-Kyung | ||||||||||
| PMID: | 29655682 | ||||||||||
| 79. | |||||||||||
| Journal: | Food Nutr Res. 2018 May 11;62. pii: 1384. | ||||||||||
| Title: | Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets. | ||||||||||
| Author: | Liang, Yu-Si|Qi, Wen-Tao|Guo, Weiqun|Wang, Chun-Ling|Hu, Ze-Bin|Li, Ai-Ke | ||||||||||
| PMID: | 29849534 | ||||||||||
| 80. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3771-3778. | ||||||||||
| Title: | Effects of miR-223 on colorectal cancer cell proliferation and apoptosis through regulating FoxO3a/BIM. | ||||||||||
| Author: | Ju, H|Tan, J-Y|Cao, B|Song, M-Q|Tian, Z-B | ||||||||||
| PMID: | 29949152 | ||||||||||
| 81. | |||||||||||
| Journal: | Cancer Immunol Res. 2018 Sep;6(9):1082-1092. | ||||||||||
| Title: | RORgammat-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells. | ||||||||||
| Author: | Rizzo, Angelamaria|Di Giovangiulio, Martina|Stolfi, Carmine|Franze, Eleonora|Fehling, Hans-Joerg|Carsetti, Rita|Giorda, Ezio|Colantoni, Alfredo|Ortenzi, Angela|Rugge, Massimo|Mescoli, Claudia|Monteleone, Giovanni|Fantini, Massimo C | ||||||||||
| PMID: | 29991500 | ||||||||||
| 82. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2018 Jul 31;37(1):178. | ||||||||||
| Title: | High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway. | ||||||||||
| Author: | Liu, Liguo|Yan, Xuebing|Wu, Dapeng|Yang, Yi|Li, Mengcheng|Su, Yang|Yang, Wenchao|Shan, Zezhi|Gao, Yuping|Jin, Zhiming | ||||||||||
| PMID: | 30064475 | ||||||||||