Primary Site >> Biliary tract Cancer

Gene >> FOXO1

Journal: J Clin Invest. 2006 Jul;116(7):1843-52. Epub 2006 Jun 8.
Title: Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.
Author: Xu, Xiaoling|Kobayashi, Shogo|Qiao, Wenhui|Li, Cuiling|Xiao, Cuiying|Radaeva, Svetlana|Stiles, Bangyan|Wang, Rui-Hong|Ohara, Nobuya|Yoshino, Tadashi|LeRoith, Derek|Torbenson, Michael S|Gores, Gregory J|Wu, Hong|Gao, Bin|Deng, Chu-Xia
PMID: 16767220
Journal: Gut. 2012 Feb;61(2):268-77.
Title: Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism.
Author: Frampton, Gabriel|Invernizzi, Pietro|Bernuzzi, Francesca|Pae, Hae Yong|Quinn, Matthew|Horvat, Darijana|Galindo, Cheryl|Huang, Li|McMillin, Matthew|Cooper, Brandon|Rimassa, Lorenza|DeMorrow, Sharon
PMID: 22068162
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Dec 1;303(11):G1202-11.
Title: The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.
Author: Frampton, Gabriel|Ueno, Yoshiyuki|Quinn, Matthew|McMillin, Matthew|Pae, Hae Yong|Galindo, Cheryl|Leyva-Illades, Dinorah|DeMorrow, Sharon
PMID: 23086914