Primary Site >> Biliary tract Cancer

Gene >> FOXO1

  • 2006
  • 2012
Ref: Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.
PMID: 16767220
 Ref: Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism.
PMID: 22068162
Ref: The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.
PMID: 23086914