Primary Site >> Colorectal Cancer

Gene >> FOSL1

Journal: J Biol Chem. 1996 Sep 20;271(38):23176-84.
Title: Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene.
Author: Lengyel, E|Wang, H|Stepp, E|Juarez, J|Wang, Y|Doe, W|Pfarr, C M|Boyd, D
PMID: 8798512
Journal: Br J Cancer. 1999 Aug;80(12):1884-91.
Title: Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis.
Author: Allgayer, H|Wang, H|Shirasawa, S|Sasazuki, T|Boyd, D
PMID: 10471035
Journal: J Biol Chem. 2000 May 19;275(20):15090-8.
Title: Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling.
Author: Qiao, D|Chen, W|Stratagoules, E D|Martinez, J D
PMID: 10748108
Journal: Crit Rev Oral Biol Med. 2001;12(2):152-65.
Title: A possible role for the WNT-1 pathway in oral carcinogenesis.
Author: Lo Muzio, L
PMID: 11345525
Journal: J Biol Chem. 2002 Feb 22;277(8):6118-23. Epub 2001 Dec 18.
Title: Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes.
Author: Tice, David A|Soloviev, Irina|Polakis, Paul
PMID: 11751871
Journal: Biochem J. 2002 Jun 1;364(Pt 2):441-7.
Title: Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
Author: Catani, M Valeria|Costanzo, Antonio|Savini, Isabella|Levrero, Massimo|de Laurenzi, Vincenzo|Wang, Jean Y J|Melino, Gerry|Avigliano, Luciana
PMID: 12023887
Journal: Int J Cancer. 2002 Oct 1;101(4):301-10.
Title: Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing beta-catenin.
Author: Wang, Hanlin L|Wang, Julia|Xiao, Shu-Yuan|Haydon, Rex|Stoiber, Debra|He, Tong-Chuan|Bissonnette, Marc|Hart, John
PMID: 12209953
Journal: Int J Cancer. 2003 Aug 20;106(2):187-97.
Title: Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin.
Author: Germann, Anja|Dihlmann, Susanne|Hergenhahn, Manfred|Doeberitz, Magnus von Knebel|Koesters, Robert
PMID: 12800193
Journal: Cancer Cell. 2003 Jul;4(1):67-79.
Title: ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Author: Vial, Emmanuel|Sahai, Erik|Marshall, Christopher J
PMID: 12892714
Journal: J Cell Sci. 2003 Dec 15;116(Pt 24):4957-63.
Title: Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells.
Author: Vial, Emmanuel|Marshall, Christopher J
PMID: 14625389
Journal: Cancer Res. 2005 Feb 15;65(4):1244-50.
Title: Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.
Author: Pollock, Claire B|Shirasawa, Senji|Sasazuki, Takehiko|Kolch, Walter|Dhillon, Amardeep S
PMID: 15735008
Journal: Am J Clin Pathol. 2005 Jul;124(1):11-9.
Title: Differential expression of the AP-1 transcription factor family members in human colorectal epithelial and neuroendocrine neoplasms.
Author: Zhang, Wanghai|Hart, John|McLeod, Howard L|Wang, Hanlin L
PMID: 15923159
Journal: Eur J Cancer. 2005 Nov;41(16):2449-61. Epub 2005 Sep 30.
Title: The Fos family of transcription factors and their role in tumourigenesis.
Author: Milde-Langosch, Karin
PMID: 16199154
Journal: Gastroenterology. 2005 Nov;129(5):1581-91.
Title: Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation.
Author: Song, Shumei|Byrd, James C|Mazurek, Nachman|Liu, Kaifeng|Koo, Ja Seok|Bresalier, Robert S
PMID: 16285957
Journal: Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8538-48.
Title: Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers.
Author: Schewe, Denis Martin|Biller, Tobias|Maurer, Gabriele|Asangani, Irfan A|Leupold, Joerg H|Lengyel, Ernst R|Post, Stefan|Allgayer, Heike
PMID: 16361535
Journal: Biochem Biophys Res Commun. 2006 Sep 22;348(2):618-27. Epub 2006 Jul 28.
Title: Aspirin upregulates expression of urokinase type plasminogen activator receptor (uPAR) gene in human colon cancer cells through AP1.
Author: Jamaluddin, Md Saha
PMID: 16893520
Journal: Mol Cancer Res. 2007 May;5(5):485-96.
Title: Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer.
Author: Leupold, Jorg H|Asangani, Irfan|Maurer, Gabriele D|Lengyel, Ernst|Post, Stefan|Allgayer, Heike
PMID: 17510314
Journal: Cancer Res. 2007 Aug 15;67(16):7572-8.
Title: Involvement of RNA helicases p68 and p72 in colon cancer.
Author: Shin, Sook|Rossow, Kari L|Grande, Joseph P|Janknecht, Ralf
PMID: 17699760
Journal: Int J Cancer. 2008 Apr 15;122(8):1745-56.
Title: Fra-1 regulates vimentin during Ha-RAS-induced epithelial mesenchymal transition in human colon carcinoma cells.
Author: Andreolas, Chrysovalantis|Kalogeropoulou, Margarita|Voulgari, Angeliki|Pintzas, Alexander
PMID: 18098284
Journal: Oncogene. 2008 Oct 16;27(47):6102-9.
Title: The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Author: Hasselblatt, P|Gresh, L|Kudo, H|Guinea-Viniegra, J|Wagner, E F
PMID: 18679426
Journal: Carcinogenesis. 2012 Mar;33(3):519-28.
Title: MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.
Author: Wu, Jianmin|Wu, Gang|Lv, Lu|Ren, Yong-Feng|Zhang, Xue-Jiao|Xue, Yong-Feng|Li, Guiling|Lu, Xincheng|Sun, ZhongSheng|Tang, Kai-Fu
PMID: 22198213
Journal: Clin Exp Metastasis. 2012 Jun;29(5):471-92.
Title: Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways.
Author: Babykutty, Suboj|Suboj, Priya|Srinivas, Priya|Nair, Asha S|Chandramohan, K|Gopala, Srinivas
PMID: 22419013
Journal: Int J Biochem Cell Biol. 2013 Feb;45(2):243-54.
Title: EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells.
Author: Ferraro, Angelo|Mourtzoukou, Despoina|Kosmidou, Vivian|Avlonitis, Spiros|Kontogeorgos, George|Zografos, George|Pintzas, Alexander
PMID: 23116973
Journal: PLoS One. 2014 Mar 21;9(3):e88950.
Title: Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells.
Author: Diesch, Jeannine|Sanij, Elaine|Gilan, Omer|Love, Christopher|Tran, Hoanh|Fleming, Nicholas I|Ellul, Jason|Amalia, Marcia|Haviv, Izhak|Pearson, Richard B|Tulchinsky, Eugene|Mariadason, John M|Sieber, Oliver M|Hannan, Ross D|Dhillon, Amardeep S
PMID: 24658684
Journal: Am J Transl Res. 2014 May 15;6(3):236-47. eCollection 2014.
Title: Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.
Author: Kim, Tae-Dong|Fuchs, James R|Schwartz, Eric|Abdelhamid, Dalia|Etter, Jonathan|Berry, William L|Li, Chenglong|Ihnat, Michael A|Li, Pui-Kai|Janknecht, Ralf
PMID: 24936217
Journal: Carcinogenesis. 2015 Apr;36(4):459-68.
Title: Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition.
Author: Liu, Hong|Ren, Guoping|Wang, Tingyang|Chen, Yuexia|Gong, Chaoju|Bai, Yanfeng|Wang, Bo|Qi, Hongyan|Shen, Jing|Zhu, Lijun|Qian, Cheng|Lai, Maode|Shao, Jimin
PMID: 25750173
Journal: Oncotarget. 2015 Dec 22;6(41):43146-61.
Title: Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival.
Author: Iskit, Sedef|Schlicker, Andreas|Wessels, Lodewyk|Peeper, Daniel S
PMID: 26646695
Journal: Cancer Lett. 2016 Jun 1;375(2):274-283.
Title: SIRT1 promotes epithelial-mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expression.
Author: Cheng, Feifei|Su, Li|Yao, Chao|Liu, Limei|Shen, Junjie|Liu, Chungang|Chen, Xuejiao|Luo, Yongli|Jiang, Lupin|Shan, Juanjuan|Chen, Jun|Zhu, Wei|Shao, Jimin|Qian, Cheng
PMID: 26975631
Journal: Onco Targets Ther. 2016 Oct 25;9:6597-6604.
Title: miR-497 suppresses epithelial-mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1.
Author: Zhang, Nan|Shen, Quan|Zhang, Pingping
PMID: 27822064
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2017 Dec 20;37(12):1654-1659.
Title: [Spleen tyrosine kinase inhibits proliferation and promotes apoptosis of colorectal cancer cells in vitro via regulating Fra-1].
Author: Xi, Zuo-Wu|Liang, Wei-Tao
PMID: 29292261
Journal: Oncol Rep. 2018 Mar;39(3):1112-1118.
Title: Fra1 enhances the radioresistance of colon cancer cells to Xray or Cion radiation.
Author: Endo, Satoshi|Fujita, Mayumi|Yamada, Shigeru|Imadome, Kaori|Nakayama, Fumiaki|Isozaki, Tetsuro|Yasuda, Takeshi|Imai, Takashi|Matsubara, Hisahiro
PMID: 29399696
Journal: Cancer Res. 2018 Aug 15;78(16):4533-4548.
Title: The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.
Author: Duong, Hong Quan|Nemazanyy, Ivan|Rambow, Florian|Tang, Seng Chuan|Delaunay, Sylvain|Tharun, Lars|Florin, Alexandra|Buttner, Reinhard|Vandaele, Daniel|Close, Pierre|Marine, Jean-Christophe|Shostak, Kateryna|Chariot, Alain
PMID: 29915160