Primary Site >> Pancreatic Cancer

Gene >> FN1

Journal: J Clin Pathol. 1981 May;34(5):504-8.
Title: Plasma fibronectin in normal subjects and in various disease states.
Author: Stathakis, N E|Fountas, A|Tsianos, E
PMID: 7251892
Journal: Cancer Res. 1981 Sep;41(9 Pt 1):3296-9.
Title: Attachment of human pancreatic tumor cell lines to collagen in vitro.
Author: McIntyre, L J|Kleinman, H K|Martin, G R|Kim, Y S
PMID: 7260895
Journal: Cancer Metastasis Rev. 1984;3(3):249-63.
Title: Cysteine proteinases and metastasis.
Author: Sloane, B F|Honn, K V
PMID: 6093995
Journal: Cancer Res. 1985 Nov;45(11 Pt 1):5246-51.
Title: Diversity of adhesion to basement membrane components of human pancreatic adenocarcinomas.
Author: Haberern, C L|Kupchik, H Z
PMID: 2932215
Journal: Pancreas. 1987;2(1):14-24.
Title: Distribution of extracellular matrix proteins in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro.
Author: Mollenhauer, J|Roether, I|Kern, H F
PMID: 3554225
Journal: J Pathol. 1991 Sep;165(1):33-41.
Title: Characterization of integrin chains in normal and neoplastic human pancreas.
Author: Hall, P A|Coates, P|Lemoine, N R|Horton, M A
PMID: 1720170
Journal: Cancer Res. 1991 Apr 15;51(8):2107-12.
Title: Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Author: Koivunen, E|Ristimaki, A|Itkonen, O|Osman, S|Vuento, M|Stenman, U H
PMID: 2009530
Journal: Int J Cancer. 1992 Nov 11;52(5):827-33.
Title: Expression and function of VLA-alpha 2, -alpha 3, -alpha 5 and -alpha 6-integrin receptors in pancreatic carcinoma.
Author: Weinel, R J|Rosendahl, A|Neumann, K|Chaloupka, B|Erb, D|Rothmund, M|Santoso, S
PMID: 1330937
Journal: J Biol Chem. 1992 Mar 25;267(9):5790-6.
Title: Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.
Author: Busk, M|Pytela, R|Sheppard, D
PMID: 1532572
Journal: Eur J Cell Biol. 1992 Jun;58(1):62-70.
Title: Monoclonal antibodies against 5'-nucleotidase from a human pancreatic tumor cell line: their characterization and inhibitory capacity on tumor cell adhesion to fibronectin substratum.
Author: Flocke, K|Lesch, G|Elsasser, H P|Bosslet, K|Mannherz, H G
PMID: 1644065
Journal: Pancreas. 1993 Nov;8(6):711-8.
Title: Expression and distribution of VLA receptors in the pancreas: an immunohistochemical study.
Author: Rosendahl, A|Neumann, K|Chaloupka, B|Rothmund, M|Weinel, R J
PMID: 8255885
Journal: Cancer Res. 1994 Apr 15;54(8):2102-7.
Title: A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6.
Author: Lehmann, M|Rabenandrasana, C|Tamura, R|Lissitzky, J C|Quaranta, V|Pichon, J|Marvaldi, J
PMID: 7513610
Journal: Exp Cell Res. 1994 Apr;211(2):175-82.
Title: Extracellular matrix components regulating glandular differentiation and the formation of basal lamina of a human pancreatic cancer cell line in vitro.
Author: Yamanari, H|Suganuma, T|Iwamura, T|Kitamura, N|Taniguchi, S|Setoguchi, T
PMID: 8143763
Journal: Z Gastroenterol. 1994 Feb;32(2):87-90.
Title: [Fibronectin in human bile--a new parameter for diagnosis of malignant bile duct processes?--A pilot study].
Author: Korner, T|Kropf, J|Jaspersen, D|Schorr, W|Hammar, C H|Gressner, A M
PMID: 8165831
Journal: Nihon Rinsho. 1995 Jul;53(7):1648-52.
Title: [Role of tripeptide Arg-Gly-Asp (RGD) on adhesiveness of human pancreatic cancer cell, PANC-1 to extracellular matrix].
Author: Sogabe, T|Nishimura, S|Chung, Y S|Sowa, M
PMID: 7630002
Journal: Int J Cancer. 1995 Aug 9;62(4):407-13.
Title: Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.
Author: Gress, T M|Muller-Pillasch, F|Lerch, M M|Friess, H|Buchler, M|Adler, G
PMID: 7635566
Journal: Cancer. 1995 Mar 15;75(6 Suppl):1554-61.
Title: Characterization of cancer cell dissociation factor in a highly invasive pancreatic cancer cell line.
Author: Kurizaki, T|Egami, H|Hirota, M|Akagi, J|Ohmachi, H|Yamamoto, S|Ogawa, M
PMID: 7889490
Journal: Int J Pancreatol. 1995 Dec;18(3):249-55.
Title: A novel adhesion factor produced by hamster pancreatic cancer cell line is effective on normal and carcinoma cell lines of different species.
Author: Toshkov, I A|Chaney, W G|Colcher, D M|Hollingsworth, M A|Bratanova, T K|Perini, F|Pour, P M
PMID: 8708397
Journal: Pancreas. 1996 Apr;12(3):248-59.
Title: Expression and function of receptors for extracellular matrix proteins in human ductal adenocarcinomas of the pancreas.
Author: Lohr, M|Trautmann, B|Gottler, M|Peters, S|Zauner, I|Maier, A|Kloppel, G|Liebe, S|Kreuser, E D
PMID: 8830331
Journal: Nihon Ika Daigaku Zasshi. 1997 Apr;64(2):163-71.
Title: [Predisposition of subclones of pancreatic carcinoma cells, AsPC-1, to changes in functional and histopathological features of xenograft tumors with response to extracellular matrix].
Author: Aida, K|Onda, M|Asano, G|Nakazawa, N
PMID: 9128054
Journal: Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8110-5.
Title: Modified cytokeratins expressed on the surface of carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment.
Author: Ditzel, H J|Garrigues, U|Andersen, C B|Larsen, M K|Garrigues, H J|Svejgaard, A|Hellstrom, I|Hellstrom, K E|Jensenius, J C
PMID: 9223323
Journal: Int J Cancer. 1999 Mar 1;80(5):791-5.
Title: Integrin alpha6beta1 role in metastatic behavior of human pancreatic carcinoma cells.
Author: Vogelmann, R|Kreuser, E D|Adler, G|Lutz, M P
PMID: 10048983
Journal: Int J Oncol. 1999 Jul;15(1):33-9.
Title: Activated lansoprazole inhibits cancer cell adhesion to extracellular matrix components.
Author: Ohta, T|Tajima, H|Yachie, A|Yokoyama, K|Elnemr, A|Fushida, S|Kitagawa, H|Kayahara, M|Nishimura, G|Miwa, K|Yamamoto, M|Terada, T|Ohkuma, S
PMID: 10375591
Journal: Pancreas. 1999 Nov;19(4):362-9.
Title: Cytokines modulate MIA PaCa 2 and CAPAN-1 adhesion to extracellular matrix proteins.
Author: Stefani, A L|Basso, D|Panozzo, M P|Greco, E|Mazza, S|Zancanaro, F|De Franchis, G|Plebani, M
PMID: 10547196
Journal: Pancreas. 2000 Mar;20(2):129-37.
Title: Beta1 integrins play an essential role in adhesion and invasion of pancreatic carcinoma cells.
Author: Arao, S|Masumoto, A|Otsuki, M
PMID: 10707927
Journal: Eur J Surg Oncol. 2001 Aug;27(5):472-6.
Title: Thrombin enhances adhesion in pancreatic cancer in vitro through the activation of the thrombin receptor PAR 1.
Author: Rudroff, C|Striegler, S|Schilli, M|Scheele, J
PMID: 11504518
Journal: Int J Gastrointest Cancer. 2002;31(1-3):41-6.
Title: TGFbeta-induced fibrogenesis of the pancreas.
Author: Menke, Andre|Adler, Guido
PMID: 12622414
Journal: Pancreas. 2003 Apr;26(3):239-42.
Title: Immunocytes and activated stellate cells in pancreatic fibrogenesis.
Author: Jaskiewicz, Kaz|Nalecz, Adam|Rzepko, Robert|Sledzinski, Zbigniew
PMID: 12657949
Journal: Strahlenther Onkol. 2003 May;179(5):337-44.
Title: Cell adhesion-mediated radioresistance (CAM-RR). Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro.
Author: Cordes, Nils|Meineke, Viktor
PMID: 12740661
Journal: Int J Biol Markers. 2003 Apr-Jun;18(2):130-8.
Title: CD44v10: an antimetastatic membrane glycoprotein for pancreatic cancer.
Author: Navaglia, F|Fogar, P|Greco, E|Basso, D|Stefani, A L|Mazza, S|Zambon, C F|Habeler, W|Altavilla, G|Amadori, A|Cecchetto, A|Plebani, M
PMID: 12841682
Journal: Gastroenterology. 2003 Oct;125(4):1188-202.
Title: Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways.
Author: Vaquero, Eva C|Edderkaoui, Mouad|Nam, Kyung J|Gukovsky, Ilya|Pandol, Stephen J|Gukovskaya, Anna S
PMID: 14517801
Journal: Int J Oncol. 2003 Nov;23(5):1277-83.
Title: Aspirin inhibits highly invasive prostate cancer cells.
Author: Lloyd, Frank P Jr|Slivova, Veronika|Valachovicova, Tatiana|Sliva, Daniel
PMID: 14532966
Journal: Pancreas. 2004 Jan;28(1):38-44.
Title: Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins.
Author: Miyamoto, Hidenori|Murakami, Tatsuya|Tsuchida, Kunihiro|Sugino, Hiromu|Miyake, Hidenori|Tashiro, Seiki
PMID: 14707728
Journal: Pancreas. 2004 Aug;29(2):85-92.
Title: The extracellular matrix differentially regulates the expression of PTHrP and the PTH/PTHrP receptor in FG pancreatic cancer cells.
Author: Grzesiak, John J|Clopton, Paul|Chalberg, Cheryl|Smith, Kathy|Burton, Douglas W|Silletti, Steve|Moossa, A R|Deftos, Leonard J|Bouvet, Michael
PMID: 15257098
Journal: Histopathology. 2004 Sep;45(3):226-36.
Title: Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro.
Author: Sipos, B|Hahn, D|Carceller, A|Piulats, J|Hedderich, J|Kalthoff, H|Goodman, S L|Kosmahl, M|Kloppel, G
PMID: 15330800
Journal: Br J Cancer. 2004 Oct 4;91(7):1327-34.
Title: Latent effects of fibronectin, alpha5beta1 integrin, alphaVbeta5 integrin and the cytoskeleton regulate pancreatic carcinoma cell IL-8 secretion.
Author: Lowrie, A G|Salter, D M|Ross, J A
PMID: 15354211
Journal: Biochem Biophys Res Commun. 2004 Oct 29;323(4):1241-5.
Title: Pancreatic cancer stimulates pancreatic stellate cell proliferation and TIMP-1 production through the MAP kinase pathway.
Author: Yoshida, Seiya|Yokota, Tokuyasu|Ujiki, Michael|Ding, Xian-Zhong|Pelham, Carolyn|Adrian, Thomas E|Talamonti, Mark S|Bell, Richard H Jr|Denham, Woody
PMID: 15451430
Journal: Mod Pathol. 2005 Jun;18(6):752-61.
Title: Expression of novel markers of pancreatic ductal adenocarcinoma in pancreatic nonductal neoplasms: additional evidence of different genetic pathways.
Author: Cao, Dengfeng|Maitra, Anirban|Saavedra, Jorge-Albores|Klimstra, David S|Adsay, N Volkan|Hruban, Ralph H
PMID: 15696124
Journal: Gastroenterology. 2005 Apr;128(4):907-21.
Title: Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells.
Author: Bachem, Max G|Schunemann, Marion|Ramadani, Marco|Siech, Marco|Beger, Hans|Buck, Andreas|Zhou, Shaoxia|Schmid-Kotsas, Alexandra|Adler, Guido
PMID: 15825074
Journal: Am J Physiol Gastrointest Liver Physiol. 2005 Dec;289(6):G1137-47. Epub 2005 Jul
Title: Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase.
Author: Edderkaoui, Mouad|Hong, Peggy|Vaquero, Eva C|Lee, Jong K|Fischer, Lars|Friess, Helmut|Buchler, Markus W|Lerch, Markus M|Pandol, Stephen J|Gukovskaya, Anna S
PMID: 16037546
Journal: Int J Biol Markers. 2005 Oct-Dec;20(4):235-41.
Title: Pancreatic cancer cells invasiveness is mainly affected by interleukin-1beta not by transforming growth factor-beta1.
Author: Greco, E|Basso, D|Fogar, P|Mazza, S|Navaglia, F|Zambon, C F|Falda, A|Pedrazzoli, S|Ancona, E|Plebani, M
PMID: 16398405
Journal: Int J Gastrointest Cancer. 2005;36(3):131-46.
Title: Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells.
Author: Grzesiak, John J|Smith, Kathy C|Chalberg, Cheryl|Burton, Douglas W|Deftos, Leonard J|Bouvet, Michael
PMID: 16720909
Journal: Br J Cancer. 2006 May 8;94(9):1311-9.
Title: The alpha2beta1 integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines.
Author: Grzesiak, J J|Bouvet, M
PMID: 16622460
Journal: Clin Cancer Res. 2006 May 15;12(10):2976-87.
Title: RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells.
Author: Tsutsumida, Hideaki|Swanson, Benjamin J|Singh, Pankaj K|Caffrey, Thomas C|Kitajima, Shinichi|Goto, Masamichi|Yonezawa, Suguru|Hollingsworth, Michael A
PMID: 16707592
Journal: Gastroenterology. 2007 Apr;132(4):1447-64.
Title: Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.
Author: Erkan, Mert|Kleeff, Jorg|Gorbachevski, Andre|Reiser, Carolin|Mitkus, Tomas|Esposito, Irene|Giese, Thomas|Buchler, Markus W|Giese, Nathalia A|Friess, Helmut
PMID: 17408641
Journal: Int J Oncol. 2007 Jun;30(6):1413-25.
Title: Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.
Author: Issat, Tadeusz|Nowis, Dominika|Legat, Magdalena|Makowski, Marcin|Klejman, Marcin P|Urbanski, Jakub|Skierski, Janusz|Koronkiewicz, Miroslawa|Stoklosa, Tomasz|Brzezinska, Agnieszka|Bil, Jacek|Gietka, Jan|Jakobisiak, Marek|Golab, Jakub
PMID: 17487362
Journal: Surgery. 2007 Jun;141(6):804-14. Epub 2007 May 4.
Title: Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells.
Author: Grzesiak, John J|Smith, Kathy C|Burton, Douglas W|Deftos, Leonard J|Bouvet, Michael
PMID: 17560257
Journal: J Biol Chem. 2007 Sep 14;282(37):26646-55.
Title: Insulin-like growth factor-I receptor mediates the prosurvival effect of fibronectin.
Author: Edderkaoui, Mouad|Hong, Peggy|Lee, Jong K|Pandol, Stephen J|Gukovskaya, Anna S
PMID: 17627944
Journal: Ann Surg Oncol. 2007 Dec;14(12):3527-33.
Title: Epithelial-mesenchymal transition (EMT) and activated extracellular signal-regulated kinase (p-Erk) in surgically resected pancreatic cancer.
Author: Javle, M M|Gibbs, J F|Iwata, K K|Pak, Y|Rutledge, P|Yu, J|Black, J D|Tan, D|Khoury, T
PMID: 17879119
Journal: BMC Cancer. 2007 Nov 12;7:209.
Title: High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition.
Author: Klein-Scory, Susanne|Zapatka, Marc|Eilert-Micus, Christina|Hoppe, Sabine|Schwarz, Elisabeth|Schmiegel, Wolff|Hahn, Stephan A|Schwarte-Waldhoff, Irmgard
PMID: 17997817
Journal: J Surg Res. 2008 Jan;144(1):117-23.
Title: Basement membrane proteins play an important role in the invasive processes of human pancreatic cancer cells.
Author: Sawai, Hirozumi|Okada, Yuji|Funahashi, Hitoshi|Takahashi, Hiroki|Matsuo, Yoichi|Yasuda, Akira|Ochi, Nobuo|Takeyama, Hiromitsu|Manabe, Tadao
PMID: 17688882
Journal: Clin Cancer Res. 2008 Aug 1;14(15):4951-60.
Title: The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer.
Author: Wagner, Karola|Schulz, Petra|Scholz, Arne|Wiedenmann, Bertram|Menrad, Andreas
PMID: 18676770
Journal: Cancer Sci. 2008 Aug;99(8):1553-63.
Title: Divalent cations modulate the integrin-mediated malignant phenotype in pancreatic cancer cells.
Author: Grzesiak, John J|Bouvet, Michael
PMID: 18754866
Journal: Pancreas. 2008 Nov;37(4):399-404.
Title: Expression of kallikrein 7 diminishes pancreatic cancer cell adhesion to vitronectin and enhances urokinase-type plasminogen activator receptor shedding.
Author: Ramani, Vishnu C|Haun, Randy S
PMID: 18953252
Journal: Int J Cancer. 2009 Jan 1;124(1):36-45.
Title: Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines.
Author: Dasgupta, Piyali|Rizwani, Wasia|Pillai, Smitha|Kinkade, Rebecca|Kovacs, Michelle|Rastogi, Shipra|Banerjee, Sarmistha|Carless, Melanie|Kim, Esther|Coppola, Domenico|Haura, Eric|Chellappan, Srikumar
PMID: 18844224
Journal: J Biol Chem. 2009 Jan 16;284(3):1385-93.
Title: The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.
Author: Zhao, Yingshe|Min, Chengyin|Vora, Siddharth R|Trackman, Philip C|Sonenshein, Gail E|Kirsch, Kathrin H
PMID: 19029090
Journal: J Biomed Opt. 2009 Mar-Apr;14(2):024032.
Title: Extended-working-distance multiphoton micromanipulation microscope for deep-penetration imaging in live mice and tissue.
Author: Makale, Milan|McElroy, Michele|O'Brien, Peter|Hoffman, Robert M|Guo, Sharon|Bouvet, Michael|Barnes, Leo|Ingulli, Elizabeth|Cheresh, David
PMID: 19405761
Journal: Neoplasia. 2009 May;11(5):497-508.
Title: Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma.
Author: Erkan, Mert|Reiser-Erkan, Carolin|Michalski, Christoph W|Deucker, Stefanie|Sauliunaite, Danguole|Streit, Sylvia|Esposito, Irene|Friess, Helmut|Kleeff, Jorg
PMID: 19412434
Journal: J Exp Clin Cancer Res. 2009 Oct 13;28:140.
Title: Alterations in integrin expression modulates invasion of pancreatic cancer cells.
Author: Walsh, Naomi|Clynes, Martin|Crown, John|O'Donovan, Norma
PMID: 19825166
Journal: Pancreas. 2009 Oct;38(7):804-10.
Title: Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer.
Author: Ryschich, Eduard|Khamidjanov, Akmal|Kerkadze, Vachtang|Buchler, Markus W|Zoller, Margot|Schmidt, Jan
PMID: 19893454
Journal: Ai Zheng. 2009 Nov;28(11):1168-75.
Title: Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Author: Zhao, Yun-Ge|Xiao, Ai-Zhen|Ni, Jian|Man, Yan-Gao|Sang, Qing-Xiang Amy
PMID: 19895737
Journal: Exp Mol Pathol. 2010 Jun;88(3):363-70.
Title: Enhanced expression of lumican inhibited the attachment and growth of human embryonic kidney 293 cells.
Author: Ishiwata, Toshiyuki|Yamamoto, Tetsushi|Kawahara, Kiyoko|Kawamoto, Yoko|Matsuda, Yoko|Ishiwata, Shunji|Naito, Zenya
PMID: 20138170
Journal: Cancer Biol Ther. 2010 Apr 15;9(8):632-9. Epub 2010 Apr 20.
Title: Antitumor effects of EMAP II against pancreatic cancer through inhibition of fibronectin-dependent proliferation.
Author: Schwarz, Roderich E|Awasthi, Niranjan|Konduri, Srivani|Caldwell, Lauren|Cafasso, Danielle|Schwarz, Margaret A
PMID: 20212356
Journal: Cancers (Basel). 2010 Sep 9;2(3):1661-82.
Title: Interaction of stellate cells with pancreatic carcinoma cells.
Author: Habisch, Hansjorg|Zhou, Shaoxia|Siech, Marco|Bachem, Max G
PMID: 24281180
Journal: Int J Oncol. 2011 Jan;38(1):133-43.
Title: Overexpression of fibroblast growth factor receptor 4 in high-grade pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
Author: Motoda, Norio|Matsuda, Yoko|Onda, Munehiko|Ishiwata, Toshiyuki|Uchida, Eiji|Naito, Zenya
PMID: 21109934
Journal: Cancer Prev Res (Phila). 2011 Jul;4(7):1107-17.
Title: Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.
Author: Sehrawat, Anuradha|Singh, Shivendra V
PMID: 21464039
Journal: Int J Cancer. 2011 Dec 15;129(12):2905-15.
Title: Knockdown of the beta(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis.
Author: Grzesiak, John J|Tran Cao, Hop S|Burton, Douglas W|Kaushal, Sharmeela|Vargas, Fabian|Clopton, Paul|Snyder, Cynthia S|Deftos, Leonard J|Hoffman, Robert M|Bouvet, Michael
PMID: 21491421
Journal: BMC Cancer. 2011 Jun 13;11:245.
Title: FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells.
Author: Lee, Hyung-Ok|Mullins, Stefanie R|Franco-Barraza, Janusz|Valianou, Matthildi|Cukierman, Edna|Cheng, Jonathan D
PMID: 21668992
Journal: PLoS One. 2011;6(6):e21684.
Title: Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway.
Author: Paron, Igor|Berchtold, Sonja|Voros, Julia|Shamarla, Madhavi|Erkan, Mert|Hofler, Heinz|Esposito, Irene
PMID: 21747918
Journal: Exp Cell Res. 2011 Oct 15;317(17):2408-19.
Title: MUC6 mucin expression inhibits tumor cell invasion.
Author: Leir, Shih-Hsing|Harris, Ann
PMID: 21851820
Journal: Transl Oncol. 2011 Oct;4(5):282-92. Epub 2011 Oct 1.
Title: Role of alpha(5)beta(1) Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells.
Author: Yao, Hongren|Zeng, Zhao-Zhu|Fay, Kevin S|Veine, Donna M|Staszewski, Evan D|Morgan, Meredith|Wilder-Romans, Kari|Williams, Terence M|Spalding, Aaron C|Ben-Josef, Edgar|Livant, Donna L
PMID: 21966545
Journal: Zhonghua Yi Xue Za Zhi. 2011 Nov 29;91(44):3103-6.
Title: [Regulatory mechanisms of Hedgehog signaling pathway for epithelial-mesenchymal transition in pancreatic cancer cells].
Author: Xie, Kun|Hao, Kun|Tian, Xiao-dong|Chang, Zhi-gang|Qin, Chang-fu|Yang, Yin-mo
PMID: 22340649
Journal: Hum Cell. 2012 Mar;25(1):1-8.
Title: Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer.
Author: Ding, Qiang|Yoshimitsu, Makoto|Kuwahata, Taisaku|Maeda, Koki|Hayashi, Tomomi|Obara, Toru|Miyazaki, Yumi|Matsubara, Shyuichiro|Natsugoe, Shoji|Takao, Sonshin
PMID: 22109279
Journal: Dig Dis Sci. 2012 May;57(5):1181-9.
Title: Suppression of the epidermal growth factor receptor inhibits epithelial-mesenchymal transition in human pancreatic cancer PANC-1 cells.
Author: Chang, Zhi-Gang|Wei, Jun-Min|Qin, Chang-Fu|Hao, Kun|Tian, Xiao-Dong|Xie, Kun|Xie, Xue-Hai|Yang, Yin-Mo
PMID: 22271412
Journal: Mol Cell Proteomics. 2012 Jul;11(7):M112.017558.
Title: Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis.
Author: Almaraz, Ruben T|Tian, Yuan|Bhattarcharya, Rahul|Tan, Elaine|Chen, Shih-Hsun|Dallas, Matthew R|Chen, Li|Zhang, Zhen|Zhang, Hui|Konstantopoulos, Konstantinos|Yarema, Kevin J
PMID: 22457533
Journal: Eur J Med Chem. 2012 Jul;53:235-45.
Title: Synthesis and evaluation of curcumin-related compounds for anticancer activity.
Author: Wei, Xingchuan|Du, Zhi-Yun|Zheng, Xi|Cui, Xiao-Xing|Conney, Allan H|Zhang, Kun
PMID: 22551677
Journal: Hepatogastroenterology. 2012 Jul-Aug;59(117):1614-20.
Title: Thrombin stimulates integrin beta1-dependent adhesion of human pancreatic cancer cells to vitronectin through protease-activated receptor (PAR)-1.
Author: Kanemaru, Mikio|Maehara, Naoki|Iwamura, Takeshi|Chijiiwa, Kazuo
PMID: 22683980
Journal: Cancer Lett. 2013 Jun 28;334(1):118-26.
Title: Grape seed proanthocyanidins inhibit migration potential of pancreatic cancer cells by promoting mesenchymal-to-epithelial transition and targeting NF-kappaB.
Author: Prasad, Ram|Katiyar, Santosh K
PMID: 22902508
Journal: Cancer Res. 2013 Apr 1;73(7):2345-56.
Title: Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells.
Author: Kozono, Shingo|Ohuchida, Kenoki|Eguchi, Daiki|Ikenaga, Naoki|Fujiwara, Kenji|Cui, Lin|Mizumoto, Kazuhiro|Tanaka, Masao
PMID: 23348422
Journal: Pancreas. 2013 Oct;42(7):1060-9.
Title: Modulation of pancreatic tumor potential by overexpression of protein kinase C beta1.
Author: Cirigliano, Stefano M|Mauro, Laura V|Grossoni, Valeria C|Colombo, Lucas L|Diament, Miriam J|Kazanietz, Marcelo G|Bal de Kier Joffe, Elisa D|Puricelli, Lydia I|Urtreger, Alejandro J
PMID: 23695799
Journal: PLoS One. 2013 Sep 10;8(9):e73345.
Title: Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model.
Author: Yeon, Sang-Eun|No, Da Yoon|Lee, Sang-Hoon|Nam, Suk Woo|Oh, Il-Hoan|Lee, Jaehwi|Kuh, Hyo-Jeong
PMID: 24039920
Journal: PLoS One. 2013 Dec 3;8(12):e81575.
Title: RhoC interacts with integrin alpha5beta1 and enhances its trafficking in migrating pancreatic carcinoma cells.
Author: Li, Ningfeng Fiona|Gemenetzidis, Emilios|Marshall, Francis J|Davies, Derek|Yu, Yongwei|Frese, Kristopher|Froeling, Fieke E M|Woolf, Adam K|Feakins, Roger M|Naito, Yoshiki|Iacobuzio-Donahue, Christine|Tuveson, David A|Hart, Ian R|Kocher, Hemant M
PMID: 24312560
Journal: Br J Cancer. 2014 Jan 21;110(2):409-20.
Title: Pancreatic stellate cells promote hapto-migration of cancer cells through collagen I-mediated signalling pathway.
Author: Lu, J|Zhou, S|Siech, M|Habisch, H|Seufferlein, T|Bachem, M G
PMID: 24201748
Journal: Biosens Bioelectron. 2014 Apr 15;54:476-83.
Title: Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma.
Author: Gach, Philip C|Attayek, Peter J|Whittlesey, Rebecca L|Yeh, Jen Jen|Allbritton, Nancy L
PMID: 24316450
Journal: Oncol Lett. 2014 Mar;7(3):658-662.
Title: miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
Author: Miao, Lifeng|Xiong, Xianze|Lin, Yixin|Cheng, Yao|Lu, Jiong|Zhang, Jie|Cheng, Nansheng
PMID: 24520289
Journal: Cell Biochem Biophys. 2014 Jun;69(2):341-6.
Title: miR-208-induced epithelial to mesenchymal transition of pancreatic cancer cells promotes cell metastasis and invasion.
Author: Liu, Anan|Shao, Chenghao|Jin, Gang|Liu, Rui|Hao, Jun|Song, Bin|Ouyang, Liu|Hu, Xiangui
PMID: 24604208
Journal: J Transl Med. 2014 Apr 5;12:87.
Title: The role of quantitative mass spectrometry in the discovery of pancreatic cancer biomarkers for translational science.
Author: Ansari, Daniel|Aronsson, Linus|Sasor, Agata|Welinder, Charlotte|Rezeli, Melinda|Marko-Varga, Gyorgy|Andersson, Roland
PMID: 24708694
Journal: Oncogene. 2015 Jan 22;34(4):455-64.
Title: Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis.
Author: Jagadeeshan, S|Krishnamoorthy, Y R|Singhal, M|Subramanian, A|Mavuluri, J|Lakshmi, A|Roshini, A|Baskar, G|Ravi, M|Joseph, L D|Sadasivan, K|Krishnan, A|Nair, A S|Venkatraman, G|Rayala, S K
PMID: 24561527
Journal: Oncogene. 2015 Feb 19;34(8):1006-18.
Title: Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis.
Author: Wang, Q|Shen, B|Chen, L|Zheng, P|Feng, H|Hao, Q|Liu, X|Liu, L|Xu, S|Chen, J|Teng, J
PMID: 24632605
Journal: Pancreatology. 2015 May-Jun;15(3):217-25.
Title: The epithelial to mesenchymal transition in pancreatic cancer: A systematic review.
Author: Beuran, Mircea|Negoi, Ionut|Paun, Sorin|Ion, Adriana Daniela|Bleotu, Coralia|Negoi, Ruxandra Irina|Hostiuc, Sorin
PMID: 25794655
Journal: Asian Pac J Cancer Prev. 2015;16(6):2561-7.
Title: Analysis of molecular pathways in pancreatic ductal adenocarcinomas with a bioinformatics approach.
Author: Wang, Yan|Li, Yan
PMID: 25824797
Journal: Nat Cell Biol. 2015 Jun;17(6):816-26.
Title: Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Author: Costa-Silva, Bruno|Aiello, Nicole M|Ocean, Allyson J|Singh, Swarnima|Zhang, Haiying|Thakur, Basant Kumar|Becker, Annette|Hoshino, Ayuko|Mark, Milica Tesic|Molina, Henrik|Xiang, Jenny|Zhang, Tuo|Theilen, Till-Martin|Garcia-Santos, Guillermo|Williams, Caitl
PMID: 25985394
Journal: Asian Pac J Cancer Prev. 2015;16(9):4065-9.
Title: Suppression of the Epidermal Growth Factor-like Domain 7 and Inhibition of Migration and Epithelial-Mesenchymal Transition in Human Pancreatic Cancer PANC-1 Cells.
Author: Wang, Yun-Liang|Dong, Feng-Lin|Yang, Jian|Li, Zhi|Zhi, Qiao-Ming|Zhao, Xin|Yang, Yong|Li, De-Chun|Shen, Xiao-Chun|Zhou, Jin
PMID: 25987088
Journal: Cancer Lett. 2016 Oct 10;381(1):252-8.
Title: Matrix control of pancreatic cancer: New insights into fibronectin signaling.
Author: Topalovski, Mary|Brekken, Rolf A
PMID: 26742464
Journal: J Biol Chem. 2016 Jul 29;291(31):16263-70.
Title: MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin.
Author: Bhardwaj, Arun|Srivastava, Sanjeev K|Singh, Seema|Tyagi, Nikhil|Arora, Sumit|Carter, James E|Khushman, Moh'd|Singh, Ajay P
PMID: 27246849
Journal: J Biol Chem. 2016 Oct 14;291(42):22244-22252.
Title: Hypoxia and Transforming Growth Factor beta Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer.
Author: Topalovski, Mary|Hagopian, Michelle|Wang, Miao|Brekken, Rolf A
PMID: 27531748
Journal: ACS Appl Mater Interfaces. 2016 Sep 14;8(36):23591-603.
Title: The Effect of Size and Geometry of Poly(acrylamide) Brush-Based Micropatterns on the Behavior of Cells.
Author: Lilge, Inga|Jiang, Siyu|Wesner, Daniel|Schonherr, Holger
PMID: 27541003
Journal: Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):296-306.
Title: Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells.
Author: Wu, Yuan Seng|Chung, Ivy|Wong, Won Fen|Masamune, Atsushi|Sim, Maw Shin|Looi, Chung Yeng
PMID: 27750041
Journal: Int J Oncol. 2017 Jan;50(1):111-120.
Title: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer.
Author: Gui, Zhifang|Luo, Feng|Yang, Yayang|Shen, Can|Li, Shuquan|Xu, Jian
PMID: 27878247
Journal: J Hematol Oncol. 2017 Jan 13;10(1):16.
Title: Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.
Author: Principe, Moitza|Borgoni, Simone|Cascione, Mariafrancesca|Chattaragada, Michelle Samuel|Ferri-Borgogno, Sammy|Capello, Michela|Bulfamante, Sara|Chapelle, Jennifer|Di Modugno, Francesca|Defilippi, Paola|Nistico, Paola|Cappello, Paola|Riganti, Chiara|Lepora
PMID: 28086938
Journal: Mol Carcinog. 2017 Sep;56(9):2066-2075.
Title: The nuclear orphan receptor NR4A1 regulates beta1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.
Author: Hedrick, Erik|Lee, Syng-Ook|Safe, Stephen
PMID: 28418095
Journal: J Cell Biol. 2017 Nov 6;216(11):3799-3816.
Title: Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.
Author: Erdogan, Begum|Ao, Mingfang|White, Lauren M|Means, Anna L|Brewer, Bryson M|Yang, Lijie|Washington, M Kay|Shi, Chanjuan|Franco, Omar E|Weaver, Alissa M|Hayward, Simon W|Li, Deyu|Webb, Donna J
PMID: 29021221
Journal: Cell Death Dis. 2017 Oct 26;8(10):e3147.
Title: Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Author: Sheng, Weiwei|Chen, Chuanping|Dong, Ming|Wang, Guosen|Zhou, Jianping|Song, He|Li, Yang|Zhang, Jian|Ding, Shuangning
PMID: 29072694
Journal: Int J Cancer. 2018 Jan 15;142(2):392-413.
Title: Potent antitumor effect of tumor microenvironment-targeted oncolytic adenovirus against desmoplastic pancreatic cancer.
Author: Li, Yan|Hong, JinWoo|Oh, Joung-Eun|Yoon, A-Rum|Yun, Chae-Ok
PMID: 28929492
Journal: Yonsei Med J. 2018 Jan;59(1):20-27.
Title: Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell.
Author: Li, Xiaoyu|Zhao, Xianzhi|Song, Wen|Tian, Zibin|Yang, Lin|Niu, Qinghui|Zhang, Qi|Xie, Man|Zhou, Bin|Xu, Yonghong|Wu, Jun|Zhang, Cuiping
PMID: 29214772
Journal: Cancer Biol Ther. 2018 Apr 3;19(4):316-327.
Title: Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
Author: Kanteti, Rajani|Mirzapoiazova, Tamara|Riehm, Jacob J|Dhanasingh, Immanuel|Mambetsariev, Bolot|Wang, Jiale|Kulkarni, Prakash|Kaushik, Garima|Seshacharyulu, Parthasarathy|Ponnusamy, Moorthy P|Kindler, Hedy L|Nasser, Mohd W|Batra, Surinder K|Salgia, Ravi
PMID: 29303405
Journal: BMC Cancer. 2018 Jan 5;18(1):36.
Title: Regulation of pancreatic stellate cell activation by Notch3.
Author: Song, Haiyan|Zhang, Yuxiang
PMID: 29304760
Journal: Oncol Rep. 2018 Mar;39(3):1347-1355.
Title: Galectin-1 expression in activated pancreatic satellite cells promotes fibrosis in chronic pancreatitis/pancreatic cancer via the TGF-beta1/Smad pathway.
Author: Tang, Dong|Wu, Qi|Zhang, Jingqiu|Zhang, Hongpeng|Yuan, Zhongxu|Xu, Jiaming|Chong, Yang|Huang, Yuqin|Xiong, Qingquan|Wang, Sen|Tian, Ying|Lu, Yongdie|Ge, Xiao|Shen, Wenjing|Wang, Daorong
PMID: 29328490
Journal: Acta Biomater. 2018 Sep 15;78:296-307.
Title: Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity.
Author: Lazzari, Gianpiero|Nicolas, Valerie|Matsusaki, Michiya|Akashi, Mitsuru|Couvreur, Patrick|Mura, Simona
PMID: 30099198
Journal: Cancer Lett. 2018 Nov 1;436:22-27.
Title: Designer hydrogels: Shedding light on the physical chemistry of the pancreatic cancer microenvironment.
Author: Lin, Chien-Chi|Korc, Murray
PMID: 30118843