Primary Site >> Liver Cancer

Gene >> FLT3

Journal: Cancer Res. 2006 Dec 15;66(24):11851-8.
Title: Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
Author: Liu, Li|Cao, Yichen|Chen, Charles|Zhang, Xiaomei|McNabola, Angela|Wilkie, Dean|Wilhelm, Scott|Lynch, Mark|Carter, Christopher
PMID: 17178882
Journal: Semin Oncol. 2006 Aug;33(4):392-406.
Title: Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.
Author: Gollob, Jared A|Wilhelm, Scott|Carter, Chris|Kelley, Susan L
PMID: 16890795
Journal: Ann Oncol. 2007 Jun;18 Suppl 6:vi22-5.
Title: Protein kinase inhibitors in the treatment of renal cell carcinoma: sorafenib.
Author: Bracarda, S|Caserta, C|Sordini, L|Rossi, M|Hamzay, A|Crino, L
PMID: 17591826
Journal: J Gastrointest Cancer. 2007;38(2-4):154-6.
Title: Effective palliation of advanced cholangiocarcinoma with sorafenib: a two-patient case report.
Author: LaRocca, Renato V|Hicks, Matthew D|Mull, Lennea|Foreman, Brenda
PMID: 19089671
Journal: BioDrugs. 2009;23(6):377-89.
Title: Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies.
Author: Papaetis, Georgios S|Syrigos, Kostas N
PMID: 19894779
Journal: Gerontology. 2010;56(3):303-9.
Title: Antiangiogenic drugs in oncology: a focus on drug safety and the elderly - a mini-review.
Author: Boehm, S|Rothermundt, C|Hess, D|Joerger, M
PMID: 19940466
Journal: Hepatogastroenterology. 2010 May-Jun;57(99-100):426-9.
Title: Effective treatment of advanced cholangiocarcinoma by hepatic arterial infusion chemotherapy combination with sorafenib: one case report from China.
Author: Qun, Wang|Tao, Yin
PMID: 20698202
Journal: Asian Pac J Cancer Prev. 2011;12(2):497-505.
Title: Elevated serum thymidine kinase 1 predicts risk of pre/early cancerous progression.
Author: Huang, Shouqing|Lin, Jianzh|Guo, Na|Zhang, Min|Yun, Xia|Liu, Song|Zhou, Ji|He, Ellen|Skog, Sven
PMID: 21545220
Journal: Eur J Med Res. 2011 Nov 10;16(11):491-4.
Title: Sunitinib induced pyoderma gangrenosum-like ulcerations.
Author: Akanay-Diesel, S|Hoff, N P|Kurle, S|Haes, J|Erhardt, A|Haussinger, D|Schulte, K-W|Bolke, Edwin|Matuschek, C|Budach, W|Gerber, P A|Homey, B
PMID: 22027642
Journal: Cancer Sci. 2012 Jan;103(1):26-33.
Title: Transforming growth factor-beta-stimulated clone-22 is a negative-feedback regulator of Ras / Raf signaling: Implications for tumorigenesis.
Author: Nakamura, Masaki|Kitaura, Jiro|Enomoto, Yutaka|Lu, Yang|Nishimura, Koutarou|Isobe, Masamichi|Ozaki, Katsutoshi|Komeno, Yukiko|Nakahara, Fumio|Oki, Toshihiko|Kume, Haruki|Homma, Yukio|Kitamura, Toshio
PMID: 21943131
Journal: Afr J Tradit Complement Altern Med. 2012 Apr 2;9(3):431-9. eCollection 2012.
Title: Discovery of potent, orally active compounds of tyrosine kinase and serine/threonine-protein kinase inhibitor with anti-tumor activity in preclinical assays.
Author: Qiu, Yun-Qing|Zhou, Jue|Kang, Xin-Shan|Shen-Tu, Jian-Zhong|Ding, Lie-Ming|Tan, Fen-Lai|Guo, Jing|Li, Lan-Juan
PMID: 23983378
Journal: Anticancer Agents Med Chem. 2012 Nov;12(9):1088-97.
Title: Rational drug design for identifying novel multi-target inhibitors for hepatocellular carcinoma.
Author: Temirak, Ahmed|Abdulla, Mona|Elhefnawi, Mahmoud
PMID: 22583422
Journal: Curr Med Chem. 2012;19(7):938-44.
Title: Sorafenib (BAY 43-9006) in hepatocellular carcinoma patients: from discovery to clinical development.
Author: Ranieri, G|Gadaleta-Caldarola, G|Goffredo, V|Patruno, R|Mangia, A|Rizzo, A|Sciorsci, R L|Gadaleta, C D
PMID: 22214462
Journal: Mediterr J Hematol Infect Dis. 2014 Feb 17;6(1):e2014016.
Title: Sorafenib Induced Hand Foot Skin Rash in FLT3 ITD Mutated Acute Myeloid Leukemia-A Case Report and Review of Literature.
Author: Senapati, Jayastu|Devasia, Anup J|Ganapule, Abhijeet|George, Leni|Viswabandya, Auro
PMID: 24678393
Journal: Onco Targets Ther. 2015 Dec 8;8:3691-701.
Title: Profile of nintedanib in the treatment of solid tumors: the evidence to date.
Author: Awasthi, Niranjan|Schwarz, Roderich E
PMID: 26677336
Journal: J Pediatr Hematol Oncol. 2016 Apr;38(3):240-2.
Title: Sorafenib-induced Posterior Reversible Encephalopathy Syndrome in a Child With FLT3-ITD-positive Acute Myeloid Leukemia.
Author: Tavil, Betul|Isgandarova, Fatma|Bayhan, Turan|Unal, Sule|Kuskonmaz, Baris|Gumruk, Fatma|Cetin, Mualla
PMID: 26907662
Journal: Turk J Med Sci. 2016 Feb 17;46(2):572-81.
Title: Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma.
Author: Aydin, Muammer Merve|Bayin, Nermin Sumru|Acun, Tolga|Yakicier, Mustafa Cengiz|Akcali, Kamil Can
PMID: 27511526
Journal: Future Oncol. 2017 Jul 13.
Title: Cabozantinib in the treatment of hepatocellular carcinoma.
Author: B Peters, Mary Linton|Miksad, Rebecca A
PMID: 28703624
Journal: J Exp Pharmacol. 2018 May 9;10:9-17.
Title: Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis.
Author: Al-Fayoumi, Suliman|Hashiguchi, Taishi|Shirakata, Yuka|Mascarenhas, John|Singer, Jack W
PMID: 29785143