Primary Site >> Pancreatic Cancer
Gene >> FLT1
| 1. | |||||||||||
| Journal: | Gastroenterology. 2000 Nov;119(5):1358-72. | ||||||||||
| Title: | De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop. | ||||||||||
| Author: | von Marschall, Z|Cramer, T|Hocker, M|Burde, R|Plath, T|Schirner, M|Heidenreich, R|Breier, G|Riecken, E O|Wiedenmann, B|Rosewicz, S | ||||||||||
| PMID: | 11054395 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Cancer. 2000 Jan 1;85(1):27-34. | ||||||||||
| Title: | Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. | ||||||||||
| Author: | Itakura, J|Ishiwata, T|Shen, B|Kornmann, M|Korc, M | ||||||||||
| PMID: | 10585578 | ||||||||||
| 3. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4605-10. Epub 2001 Mar 27. | ||||||||||
| Title: | Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. | ||||||||||
| Author: | Kuo, C J|Farnebo, F|Yu, E Y|Christofferson, R|Swearingen, R A|Carter, R|von Recum, H A|Yuan, J|Kamihara, J|Flynn, E|D'Amato, R|Folkman, J|Mulligan, R C | ||||||||||
| PMID: | 11274374 | ||||||||||
| 4. | |||||||||||
| Journal: | Pancreas. 2002 Aug;25(2):111-21. | ||||||||||
| Title: | Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor. | ||||||||||
| Author: | Hoshida, Tohru|Sunamura, Makoto|Duda, Dan G|Egawa, Shinichi|Miyazaki, Shukichi|Shineha, Ryuzaburo|Hamada, Hirofumi|Ohtani, Haruo|Satomi, Susumu|Matsuno, Seiki | ||||||||||
| PMID: | 12142732 | ||||||||||
| 5. | |||||||||||
| Journal: | Eur J Nucl Med Mol Imaging. 2002 Sep;29(9):1174-81. | ||||||||||
| Title: | Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines. | ||||||||||
| Author: | Seitz, Ulrike|Wagner, Martin|Neumaier, Bernd|Wawra, Edgar|Glatting, Gerhard|Leder, Gerhard|Schmid, Roland M|Reske, Sven N | ||||||||||
| PMID: | 12192562 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2003 Sep 15;63(18):5978-91. | ||||||||||
| Title: | CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. | ||||||||||
| Author: | Ruggeri, Bruce|Singh, Jasbir|Gingrich, Diane|Angeles, Thelma|Albom, Mark|Yang, Shi|Chang, Hong|Robinson, Candy|Hunter, Kathryn|Dobrzanski, Pawel|Jones-Bolin, Susan|Pritchard, Sonya|Aimone, Lisa|Klein-Szanto, Andres|Herbert, Jean-Marc|Bono, Francoise|Schae | ||||||||||
| PMID: | 14522925 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Cancer Res. 2004 May 15;10(10):3327-32. | ||||||||||
| Title: | Vascular endothelial growth factor-trap suppresses tumorigenicity of multiple pancreatic cancer cell lines. | ||||||||||
| Author: | Fukasawa, Mitsuharu|Korc, Murray | ||||||||||
| PMID: | 15161686 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer. 2005 Jul 15;104(2):427-38. | ||||||||||
| Title: | Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines. | ||||||||||
| Author: | Wey, Jane S|Fan, Fan|Gray, Michael J|Bauer, Todd W|McCarty, Marya F|Somcio, Ray|Liu, Wenbiao|Evans, Douglas B|Wu, Yan|Hicklin, Daniel J|Ellis, Lee M | ||||||||||
| PMID: | 15952180 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer. 2006 Apr 15;106(8):1677-84. | ||||||||||
| Title: | Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. | ||||||||||
| Author: | Chung, Gina G|Yoon, Harry H|Zerkowski, Maciej P|Ghosh, Sriparna|Thomas, Laurie|Harigopal, Malini|Charette, Lori A|Salem, Ronald R|Camp, Robert L|Rimm, David L|Burtness, Barbara A | ||||||||||
| PMID: | 16532435 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2007 Apr 1;67(7):3286-94. | ||||||||||
| Title: | Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. | ||||||||||
| Author: | Abdelrahim, Maen|Baker, Cheryl H|Abbruzzese, James L|Sheikh-Hamad, David|Liu, Shengxi|Cho, Sung Dae|Yoon, Kyungsil|Safe, Stephen | ||||||||||
| PMID: | 17409437 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Pharm. 2010 Apr 5;7(2):501-9. | ||||||||||
| Title: | Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1. | ||||||||||
| Author: | Oba, Makoto|Vachutinsky, Yelena|Miyata, Kanjiro|Kano, Mitsunobu R|Ikeda, Sorato|Nishiyama, Nobuhiro|Itaka, Keiji|Miyazono, Kohei|Koyama, Hiroyuki|Kataoka, Kazunori | ||||||||||
| PMID: | 20178335 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Sci. 2010 Jun;101(6):1529-35. | ||||||||||
| Title: | Significance of phospho-vascular endothelial growth factor receptor-2 expression in pancreatic cancer. | ||||||||||
| Author: | Doi, Yosuke|Yashiro, Masakazu|Yamada, Nobuya|Amano, Ryosuke|Ohira, Go|Komoto, Masahiro|Noda, Satoru|Kashiwagi, Shinichiro|Kato, Yukihiro|Fuyuhiro, Yuhiko|Hirakawa, Kosei | ||||||||||
| PMID: | 20367641 | ||||||||||
| 13. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2010 May 23;29:53. | ||||||||||
| Title: | RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. | ||||||||||
| Author: | Yamazoe, Sadaaki|Tanaka, Hiroaki|Sawada, Tetsuji|Amano, Ryosuke|Yamada, Nobuya|Ohira, Masaichi|Hirakawa, Kosei | ||||||||||
| PMID: | 20492722 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Res. 2010 Aug 1;70(15):6283-92. | ||||||||||
| Title: | Transplanting normal vascular proangiogenic cells to tumor-bearing mice triggers vascular remodeling and reduces hypoxia in tumors. | ||||||||||
| Author: | Sasajima, Junpei|Mizukami, Yusuke|Sugiyama, Yoshiaki|Nakamura, Kazumasa|Kawamoto, Toru|Koizumi, Kazuya|Fujii, Rie|Motomura, Wataru|Sato, Kazuya|Suzuki, Yasuaki|Tanno, Satoshi|Fujiya, Mikihiro|Sasaki, Katsunori|Shimizu, Norihiko|Karasaki, Hidenori|Kono, To | ||||||||||
| PMID: | 20631070 | ||||||||||
| 15. | |||||||||||
| Journal: | Clin J Gastroenterol. 2010 Dec;3(6):307-17. | ||||||||||
| Title: | Gastrointestinal bleeding during anti-angiogenic peptide vaccination in combination with gemcitabine for advanced pancreatic cancer. | ||||||||||
| Author: | Nagayama, Hitomi|Matsumoto, Kazufumi|Isoo, Naoyuki|Ohno, Hideki|Takahashi, Naoyuki|Nakaoka, Takashi|Shinozaki, Masaru|Watanabe, Makoto|Inoue, Yusuke|Nagamura, Fumitaka|Oyaizu, Naoki|Yamashita, Naohide | ||||||||||
| PMID: | 26190488 | ||||||||||
| 16. | |||||||||||
| Journal: | BMC Cancer. 2011 Jul 5;11:286. | ||||||||||
| Title: | Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. | ||||||||||
| Author: | Rahbari, Nuh N|Schmidt, Thomas|Falk, Christine S|Hinz, Ulf|Herber, Magdalene|Bork, Ulrich|Buchler, Markus W|Weitz, Jurgen|Koch, Moritz | ||||||||||
| PMID: | 21729304 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Cancer Res. 2012 May 15;18(10):2838-49. | ||||||||||
| Title: | Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. | ||||||||||
| Author: | Speisky, Daniela|Duces, Aurelie|Bieche, Ivan|Rebours, Vinciane|Hammel, Pascal|Sauvanet, Alain|Richard, Stephane|Bedossa, Pierre|Vidaud, Michel|Murat, Arnaud|Niccoli, Patricia|Scoazec, Jean-Yves|Ruszniewski, Philippe|Couvelard, Anne | ||||||||||
| PMID: | 22461457 | ||||||||||
| 18. | |||||||||||
| Journal: | Pancreas. 2013 Apr;42(3):411-21. | ||||||||||
| Title: | Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors. | ||||||||||
| Author: | Gilbert, Judith A|Adhikari, Laura J|Lloyd, Ricardo V|Halfdanarson, Thorvardur R|Muders, Michael H|Ames, Matthew M | ||||||||||
| PMID: | 23211371 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncoimmunology. 2013 Nov 1;2(11):e27010. | ||||||||||
| Title: | Immunological responses to a multi-peptide vaccine targeting cancer-testis antigens and VEGFRs in advanced pancreatic cancer patients. | ||||||||||
| Author: | Okuyama, Ryuji|Aruga, Atsushi|Hatori, Takashi|Takeda, Kazuyoshi|Yamamoto, Masakazu | ||||||||||
| PMID: | 24498547 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2013 Sep 9;8(9):e73940. | ||||||||||
| Title: | DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ali, Naushad|Lightfoot, Stan A|Pantazis, Panayotis|Rao, Chinthalapally V|Postier, Russell G|Houchen, Courtney W | ||||||||||
| PMID: | 24040120 | ||||||||||
| 21. | |||||||||||
| Journal: | Acta Oncol. 2014 Jan;53(1):103-12. | ||||||||||
| Title: | VEGFR1 single nucleotide polymorphisms associated with outcome in patients with metastatic renal cell carcinoma treated with sunitinib - a multicentric retrospective analysis. | ||||||||||
| Author: | Beuselinck, Benoit|Karadimou, Alexandra|Lambrechts, Diether|Claes, Bart|Wolter, Pascal|Couchy, Gabrielle|Berkers, Joost|van Poppel, Hendrik|Paridaens, Robert|Schoffski, Patrick|Mejean, Arnaud|Verkarre, Virginie|Lerut, Evelyne|Joly, Florence|Lebret, Thierr | ||||||||||
| PMID: | 23421954 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Lett. 2014 Aug 28;351(1):151-61. | ||||||||||
| Title: | XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W | ||||||||||
| PMID: | 24880079 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pathol. 2014 Oct;234(2):214-27. | ||||||||||
| Title: | Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer. | ||||||||||
| Author: | Martinez-Bosch, Neus|Iglesias, Mar|Munne-Collado, Jessica|Martinez-Caceres, Carlos|Moreno, Mireia|Guerra, Carmen|Yelamos, Jose|Navarro, Pilar | ||||||||||
| PMID: | 24889936 | ||||||||||
| 24. | |||||||||||
| Journal: | Vasc Cell. 2014 Sep 6;6:18. | ||||||||||
| Title: | Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage. | ||||||||||
| Author: | Yamamoto, Yuji|Matsui, Junji|Matsushima, Tomohiro|Obaishi, Hiroshi|Miyazaki, Kazuki|Nakamura, Katsuji|Tohyama, Osamu|Semba, Taro|Yamaguchi, Atsumi|Hoshi, Sachi Suzuki|Mimura, Fusayo|Haneda, Toru|Fukuda, Yoshio|Kamata, Jun-Ichi|Takahashi, Keiko|Matsukura, | ||||||||||
| PMID: | 25197551 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Lett. 2015 Mar 1;358(1):59-66. | ||||||||||
| Title: | Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer. | ||||||||||
| Author: | Awasthi, Niranjan|Hinz, Stefan|Brekken, Rolf A|Schwarz, Margaret A|Schwarz, Roderich E | ||||||||||
| PMID: | 25527450 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Imaging Radionucl Ther. 2015 Jun 5;24(2):71-9. | ||||||||||
| Title: | Proliferative and Glycolytic Assessment of the Whole-Body Bone Marrow Compartment. | ||||||||||
| Author: | Goryawala, Mohammed|Adjoua, Malek|Gulec, Seza | ||||||||||
| PMID: | 26316472 | ||||||||||
| 27. | |||||||||||
| Journal: | Rom J Intern Med. 2015 Jul-Sep;53(3):199-208. | ||||||||||
| Title: | VEGF Expression in Pancreatic Cancer and Other Malignancies: A Review of the Literature. | ||||||||||
| Author: | Costache, M I|Ioana, Mihai|Iordache, Sevastita|Ene, D|Costache, Cornelia Alexandra|Saftoiu, A | ||||||||||
| PMID: | 26710495 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Imaging Radionucl Ther. 2016 Feb 5;25(1):32-8. | ||||||||||
| Title: | 18F-FLT Positron Emission Tomography/Computed Tomography Imaging in Pancreatic Cancer: Determination of Tumor Proliferative Activity and Comparison with Glycolytic Activity as Measured by 18F-FDG Positron Emission Tomography/Computed Tomography Imaging. | ||||||||||
| Author: | Debebe, Senait Aknaw|Goryawala, Mohammed|Adjouadi, Malek|Mcgoron, Anthony J|Gulec, Seza A | ||||||||||
| PMID: | 27299286 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 15;7(46):75319-75327. | ||||||||||
| Title: | Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase. | ||||||||||
| Author: | Choi, Sung S|Yoon, Kichul|Choi, Seon-A|Yoon, Seung-Bin|Kim, Seung U|Lee, Hong J | ||||||||||
| PMID: | 27659534 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Sci. 2017 Jan;108(1):73-80. | ||||||||||
| Title: | Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study. | ||||||||||
| Author: | Suzuki, Nobuaki|Hazama, Shoichi|Iguchi, Haruo|Uesugi, Kazuhiro|Tanaka, Hiroaki|Hirakawa, Kosei|Aruga, Atsushi|Hatori, Takashi|Ishizaki, Hidenobu|Umeda, Yuzo|Fujiwara, Toshiyoshi|Ikemoto, Tetsuya|Shimada, Mitsuo|Yoshimatsu, Kazuhiko|Shimizu, Ryoichi|Hayash | ||||||||||
| PMID: | 27783849 | ||||||||||
| 31. | |||||||||||
| Journal: | J Control Release. 2017 Jan 10;245:1-14. | ||||||||||
| Title: | Triple-amiRNA VEGFRs inhibition in pancreatic cancer improves the efficacy of chemotherapy through EMT regulation. | ||||||||||
| Author: | Huang, Jianfei|Mei, Haijun|Tang, Zhiyuan|Li, Jieying|Zhang, Xiaojing|Lu, Yixiang|Huang, Fang|Jin, Qin|Wang, Zhiwei | ||||||||||
| PMID: | 27889393 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Pharm. 2017 Jan 30;517(1-2):157-167. | ||||||||||
| Title: | Effective targeting of gemcitabine to pancreatic cancer through PEG-cored Flt-1 antibody-conjugated dendrimers. | ||||||||||
| Author: | Ozturk, Kivilcim|Esendagli, Gunes|Gurbuz, Mustafa Ulvi|Tulu, Metin|Calis, Sema | ||||||||||
| PMID: | 27965135 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncol Lett. 2017 Oct;14(4):4647-4658. | ||||||||||
| Title: | TNFalpha and TGFbeta-1 synergistically increase the cancer stem cell properties of MiaPaCa-2 cells. | ||||||||||
| Author: | Kali, Aikyn|Ostapchuk, Yekaterina O|Belyaev, Nikolai N | ||||||||||
| PMID: | 29085463 | ||||||||||
| 34. | |||||||||||
| Journal: | Mol Pharm. 2018 Apr 2;15(4):1526-1533. | ||||||||||
| Title: | Tumor-Induced Myeloid Cells Are Reduced by Gemcitabine-Loaded PAMAM Dendrimers Decorated with Anti-Flt1 Antibody. | ||||||||||
| Author: | Yoyen-Ermis, Digdem|Ozturk-Atar, Kivilcim|Kursunel, M Alper|Aydin, Cisel|Ozkazanc, Didem|Gurbuz, Mustafa Ulvi|Uner, Aysegul|Tulu, Metin|Calis, Sema|Esendagli, Gunes | ||||||||||
| PMID: | 29481086 | ||||||||||