Primary Site >> Pancreatic Cancer
Gene >> FLT1
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Ref: Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. PMID: 10585578 Ref: De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop. PMID: 11054395 |
Ref: Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. PMID: 11274374 |
Ref: Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor. PMID: 12142732 Ref: Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines. PMID: 12192562 |
Ref: CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. PMID: 14522925 |
Ref: Vascular endothelial growth factor-trap suppresses tumorigenicity of multiple pancreatic cancer cell lines. PMID: 15161686 |
Ref: Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines. PMID: 15952180 |
Ref: Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. PMID: 16532435 |
Ref: Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. PMID: 17409437 |
Ref: Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1. PMID: 20178335 Ref: Significance of phospho-vascular endothelial growth factor receptor-2 expression in pancreatic cancer. PMID: 20367641 Ref: RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. PMID: 20492722 Ref: Transplanting normal vascular proangiogenic cells to tumor-bearing mice triggers vascular remodeling and reduces hypoxia in tumors. PMID: 20631070 Ref: Gastrointestinal bleeding during anti-angiogenic peptide vaccination in combination with gemcitabine for advanced pancreatic cancer. PMID: 26190488 |
Ref: Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. PMID: 21729304 |
Ref: Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. PMID: 22461457 |
Ref: Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors. PMID: 23211371 Ref: DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. PMID: 24040120 Ref: Immunological responses to a multi-peptide vaccine targeting cancer-testis antigens and VEGFRs in advanced pancreatic cancer patients. PMID: 24498547 |
Ref: VEGFR1 single nucleotide polymorphisms associated with outcome in patients with metastatic renal cell carcinoma treated with sunitinib - a multicentric retrospective analysis. PMID: 23421954 Ref: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. PMID: 24880079 Ref: Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer. PMID: 24889936 Ref: Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage. PMID: 25197551 |
Ref: Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer. PMID: 25527450 Ref: Proliferative and Glycolytic Assessment of the Whole-Body Bone Marrow Compartment. PMID: 26316472 Ref: VEGF Expression in Pancreatic Cancer and Other Malignancies: A Review of the Literature. PMID: 26710495 |
Ref: 18F-FLT Positron Emission Tomography/Computed Tomography Imaging in Pancreatic Cancer: Determination of Tumor Proliferative Activity and Comparison with Glycolytic Activity as Measured by 18F-FDG Positron Emission Tomography/Computed Tomography Imaging. PMID: 27299286 Ref: Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase. PMID: 27659534 |
Ref: Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study. PMID: 27783849 Ref: Triple-amiRNA VEGFRs inhibition in pancreatic cancer improves the efficacy of chemotherapy through EMT regulation. PMID: 27889393 Ref: Effective targeting of gemcitabine to pancreatic cancer through PEG-cored Flt-1 antibody-conjugated dendrimers. PMID: 27965135 Ref: TNFalpha and TGFbeta-1 synergistically increase the cancer stem cell properties of MiaPaCa-2 cells. PMID: 29085463 |
Ref: Tumor-Induced Myeloid Cells Are Reduced by Gemcitabine-Loaded PAMAM Dendrimers Decorated with Anti-Flt1 Antibody. PMID: 29481086 |