Primary Site >> Colorectal Cancer

Gene >> FHL2

Journal: Gastroenterology. 2007 Mar;132(3):1066-76. Epub 2006 Dec 3.
Title: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis.
Author: Wang, Jide|Yang, Yi|Xia, Harry H X|Gu, Qing|Lin, Marie C M|Jiang, Bo|Peng, Ying|Li, Guoqing|An, Xiaomeng|Zhang, Yali|Zhuang, Zehao|Zhang, Zhenshu|Kung, Hsiang Fu|Wong, Benjamin C Y
PMID: 17383428
Journal: Pathol Oncol Res. 2009 Mar;15(1):31-6.
Title: Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer.
Author: Qiao, Liang|Wang, Yan|Pang, Roberta|Wang, Jide|Dai, Yun|Ma, Juan|Gu, Qing|Li, Zesong|Zhang, Yusheng|Zou, Bing|Lan, H Y|Wong, Benjamin C Y
PMID: 18752053
Journal: Nanotechnology. 2009 Oct 7;20(40):405103.
Title: Functional gene silencing mediated by chitosan/siRNA nanocomplexes.
Author: Ji, A M|Su, D|Che, O|Li, W S|Sun, L|Zhang, Z Y|Yang, B|Xu, F
PMID: 19752491
Journal: Oncol Rep. 2010 Jun;23(6):1669-74.
Title: FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29.
Author: Amann, Thomas|Egle, Yvonne|Bosserhoff, Anja-Katrin|Hellerbrand, Claus
PMID: 20428824
Journal: PLoS One. 2010 Apr 28;5(4):e10371.
Title: Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.
Author: Labalette, Charlotte|Nouet, Yann|Levillayer, Florence|Colnot, Sabine|Chen, Ju|Claude, Valere|Huerre, Michel|Perret, Christine|Buendia, Marie-Annick|Wei, Yu
PMID: 20442768
Journal: Carcinogenesis. 2010 Jul;31(7):1220-9.
Title: Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer.
Author: Zhang, Wenjing|Jiang, Bo|Guo, Zheng|Sardet, Claude|Zou, Bing|Lam, Colin S C|Li, Jianming|He, Mingliang|Lan, Hui-Yao|Pang, Roberta|Hung, I F N|Tan, V P Y|Wang, Jide|Wong, Benjamin C Y
PMID: 20460358
Journal: Eur J Cancer. 2011 Jan;47(1):121-30.
Title: Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1.
Author: Zhang, Wenjing|Wang, Jide|Zou, Bing|Sardet, Claude|Li, Jianming|Lam, Colin S C|Ng, Lui|Pang, Roberta|Hung, Ivan F N|Tan, Victoria P Y|Jiang, Bo|Wong, Benjamin C Y
PMID: 20801642
Journal: Lab Invest. 2011 Dec;91(12):1695-705.
Title: FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer.
Author: Gullotti, Lucia|Czerwitzki, Jacqueline|Kirfel, Jutta|Propping, Peter|Rahner, Nils|Steinke, Verena|Kahl, Philip|Engel, Christoph|Schule, Roland|Buettner, Reinhard|Friedrichs, Nicolaus
PMID: 21826055
Journal: Br J Cancer. 2013 Jul 9;109(1):114-20.
Title: Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer.
Author: Verset, L|Tommelein, J|Moles Lopez, X|Decaestecker, C|Mareel, M|Bracke, M|Salmon, I|De Wever, O|Demetter, P
PMID: 23756870
Journal: Int J Oncol. 2013 Nov;43(5):1618-26.
Title: A novel colon cancer gene therapy using rAAVmediated expression of human shRNA-FHL2.
Author: Wu, Yao|Guo, Zheng|Zhang, Di|Zhang, Wenjing|Yan, Qingqing|Shi, Xinpeng|Zhang, Mengnan|Zhao, Yingying|Zhang, Yali|Jiang, Bo|Cheng, Tianming|Bai, Yang|Wang, Jide
PMID: 24008552
Journal: Pathol Res Pract. 2015 Feb;211(2):171-4.
Title: Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer.
Author: Al-Nomani, Lukman|Friedrichs, Jacqueline|Schule, Roland|Buttner, Reinhard|Friedrichs, Nicolaus
PMID: 25554651
Journal: Oncotarget. 2015 Sep 22;6(28):25402-17.
Title: KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.
Author: Yan, Qingqing|Zhang, Wenjing|Wu, Yao|Wu, Meiyan|Zhang, Mengnan|Shi, Xinpeng|Zhao, Jinjun|Nan, Qingzhen|Chen, Ye|Wang, Long|Cheng, Tianming|Li, Jiachu|Bai, Yang|Liu, Side|Wang, Jide
PMID: 26320172
Journal: Oncogenesis. 2016 Nov 28;5(11):e271.
Title: FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer.
Author: Wu, M|Wang, J|Tang, W|Zhan, X|Li, Y|Peng, Y|Huang, X|Bai, Y|Zhao, J|Li, A|Chen, C|Chen, Y|Peng, H|Ren, Y|Li, G|Liu, S|Wang, J
PMID: 27892920
Journal: Tumour Biol. 2017 Mar;39(3):1010428317695024.
Title: ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer.
Author: Verset, Laurine|Tommelein, Joke|Decaestecker, Christine|De Vlieghere, Elly|Bracke, Marc|Salmon, Isabelle|De Wever, Olivier|Demetter, Pieter
PMID: 28349819
Journal: Oncotarget. 2017 Apr 4;8(14):23237-23245.
Title: Acceleration of leukocytes' epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer.
Author: Durso, Danielle Fernandes|Bacalini, Maria Giulia|Sala, Claudia|Pirazzini, Chiara|Marasco, Elena|Bonafe, Massimiliano|do Valle, Italo Faria|Gentilini, Davide|Castellani, Gastone|Faria, Ana Maria Caetano|Franceschi, Claudio|Garagnani, Paolo|Nardini, Christi
PMID: 28423572