Primary Site >> Colorectal Cancer
Gene >> FHL2
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Ref: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. PMID: 17383428 |
Ref: Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer. PMID: 18752053 Ref: Functional gene silencing mediated by chitosan/siRNA nanocomplexes. PMID: 19752491 |
Ref: FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29. PMID: 20428824 Ref: Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice. PMID: 20442768 Ref: Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer. PMID: 20460358 |
Ref: Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1. PMID: 20801642 Ref: FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer. PMID: 21826055 |
Ref: Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer. PMID: 23756870 Ref: A novel colon cancer gene therapy using rAAVmediated expression of human shRNA-FHL2. PMID: 24008552 |
Ref: Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer. PMID: 25554651 Ref: KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. PMID: 26320172 |
Ref: FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer. PMID: 27892920 |
Ref: ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer. PMID: 28349819 Ref: Acceleration of leukocytes' epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer. PMID: 28423572 |