Literatures

Primary Site >> Stomach Cancer

Gene >> FHIT

1.
Journal:	Cancer Res. 1996 Mar 1;56(5):978-83.
Title:	Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
Author:	Kastury, K\|Baffa, R\|Druck, T\|Ohta, M\|Cotticelli, M G\|Inoue, H\|Negrini, M\|Rugge, M\|Huang, D\|Croce, C M\|Palazzo, J\|Huebner, K
PMID:	8640789

2.
Journal:	Genes Chromosomes Cancer. 1997 Sep;20(1):98-102.
Title:	Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines.
Author:	Tamura, G\|Sakata, K\|Nishizuka, S\|Maesawa, C\|Suzuki, Y\|Iwaya, T\|Terashima, M\|Saito, K\|Satodate, R
PMID:	9290961

3.
Journal:	Cancer Res. 1998 Oct 15;58(20):4708-14.
Title:	Loss of FHIT expression in gastric carcinoma.
Author:	Baffa, R\|Veronese, M L\|Santoro, R\|Mandes, B\|Palazzo, J P\|Rugge, M\|Santoro, E\|Croce, C M\|Huebner, K
PMID:	9788626

4.
Journal:	Cancer Res. 1999 Feb 1;59(3):748-52.
Title:	Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas.
Author:	van Dekken, H\|Geelen, E\|Dinjens, W N\|Wijnhoven, B P\|Tilanus, H W\|Tanke, H J\|Rosenberg, C
PMID:	9973227

5.
Journal:	J Pathol. 1999 Aug;188(4):378-81.
Title:	FHIT gene in gastric cancer: association with tumour progression and prognosis.
Author:	Noguchi, T\|Muller, W\|Wirtz, H C\|Willers, R\|Gabbert, H E
PMID:	10440747

6.
Journal:	Cancer. 2000 Jan 1;88(1):24-34.
Title:	Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival.
Author:	Capuzzi, D\|Santoro, E\|Hauck, W W\|Kovatich, A J\|Rosato, F E\|Baffa, R\|Huebner, K\|McCue, P A
PMID:	10618602

7.
Journal:	Hunan Yi Ke Da Xue Xue Bao. 2000 Aug 28;25(4):331-3.
Title:	[Abnormal expression of the FHIT gene in human primary gastrointestinal cancers].
Author:	Duan, X M\|Zhang, G Y\|Wu, E S
PMID:	12205991

8.
Journal:	Biochem Biophys Res Commun. 2001 Jun 15;284(3):850-5.
Title:	Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas.
Author:	Lee, S H\|Kim, W H\|Kim, H K\|Woo, K M\|Nam, H S\|Kim, H S\|Kim, J G\|Cho, M H
PMID:	11396980

9.
Journal:	Oncol Rep. 2001 Nov-Dec;8(6):1233-7.
Title:	Fhit protein expression in human gastric cancer and related precancerous lesions.
Author:	Caselli, M\|Marchisio, M\|Gaudio, M\|Saragoni, L\|Lanza, G\|Alvisi, V\|Bertagnolo, V\|Concu, M\|Capitani, S\|Caramelli, E
PMID:	11605039

10.
Journal:	Exp Mol Med. 2001 Sep 30;33(3):124-30.
Title:	Characterization of aberrant FHIT transcripts in gastric adenocarcinomas.
Author:	Lee, S H\|Kim, C J\|Park, H K\|Koh, J W\|Cho, M H\|Baek, M J\|Lee, M S
PMID:	11642547

11.
Journal:	Eur J Cancer. 2002 Mar;38(5):728-35.
Title:	High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer.
Author:	Huiping, C\|Kristjansdottir, S\|Bergthorsson, J T\|Jonasson, J G\|Magnusson, J\|Egilsson, V\|Ingvarsson, S
PMID:	11916557

12.
Journal:	Lab Invest. 2002 Sep;82(9):1201-8.
Title:	Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer.
Author:	Chang, Yu-Ting\|Wu, Ming-Shiang\|Chang, Chee-Jen\|Huang, Pei-Hsin\|Hsu, Su-Ming\|Lin, Jaw-Town
PMID:	12218081

13.
Journal:	Res Commun Mol Pathol Pharmacol. 2002;112(1-4):39-49.
Title:	Aberrant splicing of FHIT transcripts in human gastric cancer cell lines.
Author:	Lee, Sang-Han\|Kim, Ho-Young\|Kim, Tae-Jung\|Park, Hyun-Kyoung\|Kim, Woo-Hyoung\|Woo, Kee-Min\|Cho, Man-Hee
PMID:	15080495

14.
Journal:	Eur J Gastroenterol Hepatol. 2003 May;15(5):515-23.
Title:	Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Author:	Skopelitou, Antigone S\|Mitselou, Antigone\|Katsanos, Konstantinos H\|Alexopoulou, Vana\|Tsianos, Epameinondas V
PMID:	12702909

15.
Journal:	Korean J Gastroenterol. 2003 Dec;42(6):476-83.
Title:	[Sequence analyses of aberrant FHIT transcripts in gastric cancer cell lines].
Author:	Lee, Sang Han\|Kim, Hong Soo
PMID:	14695704

16.
Journal:	FASEB J. 2003 Sep;17(12):1768-70. Epub 2003 Jul 3.
Title:	Regression of upper gastric cancer in mice by FHIT gene delivery.
Author:	Ishii, Hideshi\|Zanesi, Nicola\|Vecchione, Andrea\|Trapasso, Francesco\|Yendamuri, Sai\|Sarti, Manuela\|Baffa, Raffaele\|During, Matthew J\|Huebner, Kay\|Fong, Louise Y Y\|Croce, Carlo M
PMID:	12958204

17.
Journal:	Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7824-9.
Title:	Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis.
Author:	Su, Tao\|Suzui, Masumi\|Wang, Lei\|Lin, Chyuan-Sheng\|Xing, Wang-Qiu\|Weinstein, I Bernard
PMID:	12810953

18.
Journal:	J Pathol. 2003 May;200(1):39-46.
Title:	Tumour suppressor gene expression correlates with gastric cancer prognosis.
Author:	Lee, Hye Seung\|Lee, Hyeon Kook\|Kim, Hee Sung\|Yang, Han-Kwang\|Kim, Woo Ho
PMID:	12692839

19.
Journal:	J Cancer Res Clin Oncol. 2003 Feb;129(2):84-8. Epub 2003 Mar 4.
Title:	Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer.
Author:	Rocco, Alba\|Schandl, Laslo\|Chen, Jie\|Wang, Hongbing\|Tulassay, Zsolt\|McNamara, Deirdre\|Malfertheiner, Peter\|Ebert, Matthias P A
PMID:	12669232

20.
Journal:	Clin Cancer Res. 2004 Mar 1;10(5):1698-705.
Title:	Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma.
Author:	Lee, Hye Seung\|Chang, Mee Soo\|Yang, Han-Kwang\|Lee, Byung Lan\|Kim, Woo Ho
PMID:	15014022

21.
Journal:	Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Mar;33(2):133-7.
Title:	[Effect of fragile histidine triad gene on apoptosis of MGC-803 gastric cancer cells].
Author:	Kong, Mei\|Chen, Wei-zhe\|Chen, Zhi\|Li, Min-wei
PMID:	15067734

22.
Journal:	Clin Cancer Res. 2004 May 1;10(9):3053-8.
Title:	Loss of WWOX expression in gastric carcinoma.
Author:	Aqeilan, Rami I\|Kuroki, Tamotsu\|Pekarsky, Yuri\|Albagha, Omar\|Trapasso, Francesco\|Baffa, Raffaele\|Huebner, Kay\|Edmonds, Pamela\|Croce, Carlo M
PMID:	15131042

23.
Journal:	World J Gastroenterol. 2005 Jan 7;11(1):17-21.
Title:	Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection.
Author:	Stec-Michalska, Krystyna\|Antoszczyk, Slawomir\|Klupinska, Grazyna\|Nawrot, Barbara
PMID:	15609389

24.
Journal:	Eur J Hum Genet. 2005 May;13(5):570-8.
Title:	About the origin and development of hereditary conventional renal cell carcinoma in a four-generation t(3;8)(p14.1;q24.23) family.
Author:	Valle, Laura\|Cascon, Alberto\|Melchor, Lorenzo\|Otero, Ignacio\|Rodriguez-Perales, Sandra\|Sanchez, Lydia\|Cruz Cigudosa, Juan\|Robledo, Mercedes\|Weber, Barbara\|Urioste, Miguel\|Benitez, Javier
PMID:	15756303

25.
Journal:	World J Gastroenterol. 2005 Jun 7;11(21):3212-6.
Title:	Relationship between abnormality of FHIT gene and EBV infection in gastric cancer.
Author:	Xiao, Yu-Ping\|Han, Cheng-Bo\|Mao, Xiao-Yun\|Li, Jin-Yi\|Xu, Lei\|Ren, Chang-Shan\|Xin, Yan
PMID:	15929169

26.
Journal:	Rev Med Chil. 2005 Aug;133(8):874-80.
Title:	[Promoter methylation profile in gastric cancer].
Author:	Roa, Juan Carlos\|Anabalon, Leonardo\|Roa, Ivan\|Tapia, Oscar\|Melo, Angelica\|Villaseca, Miguel\|Araya, Juan Carlos
PMID:	16163424

27.
Journal:	World J Gastroenterol. 2005 Sep 28;11(36):5735-8.
Title:	Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Author:	Zhao, Po\|Liu, Wu\|Lu, Ya-Li
PMID:	16237777

28.
Journal:	J Cancer Res Clin Oncol. 2006 Jan;132(1):45-50. Epub 2005 Oct 11.
Title:	Loss of Fhit expression is associated with poorer survival in gastric cancer but is not an independent prognostic marker.
Author:	Bragantini, Emma\|Barbi, Stefano\|Beghelli, Stefania\|Moore, Patrick S\|de Manzoni, Giovanni\|Roviello, Franco\|Tomezzoli, Anna\|Vindigni, Carla\|Baffa, Raffaele\|Scarpa, Aldo
PMID:	16217683

29.
Journal:	World J Gastroenterol. 2006 Jun 21;12(23):3766-9.
Title:	Loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma.
Author:	Xiao, Yu-Ping\|Wu, Dong-Ying\|Xu, Lei\|Xin, Yan
PMID:	16773697

30.
Journal:	J Clin Pathol. 2007 Mar;60(3):273-7. Epub 2006 May 19.
Title:	Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: an immunostaining study on the tissue microarray.
Author:	Zheng, Huachuan\|Takahashi, Hiroyuki\|Murai, Yoshihiro\|Cui, Zhengguo\|Nomoto, Kazuhiro\|Miwa, Shigeharu\|Tsuneyama, Koichi\|Takano, Yasuo
PMID:	16714395

31.
Journal:	Rev Med Chil. 2007 Jan;135(1):17-25. Epub 2007 Mar 6.
Title:	[Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes].
Author:	Zavala G, Luis\|Luengo J, Victor\|Ossandon C, Francisco\|Riquelme S, Erick\|Backhouse E, Claudia\|Palma V, Mariana\|Argandona C, Jorge\|Cumsille, Miguel Angel\|Corvalan R, Alejandro
PMID:	17369979

32.
Journal:	World J Gastroenterol. 2007 May 14;13(18):2568-74.
Title:	Promoter hypermethylation of CDH1, FHIT, MTAP and PLAGL1 in gastric adenocarcinoma in individuals from Northern Brazil.
Author:	Leal, Mariana Ferreira\|Lima, Eleonidas Moura\|Silva, Patricia Natalia Oliveira\|Assumpcao, Paulo Pimentel\|Calcagno, Danielle Queiroz\|Payao, Spencer Luiz Marques\|Burbano, Rommel Rodriguez\|Smith, Marilia Arruda Cardoso
PMID:	17552003

33.
Journal:	Oncol Rep. 2007 Sep;18(3):553-9.
Title:	Expression of Fhit, Mlh1, p16INK4A and E-cadherin in early gastric neoplasia: Correlation with histological grade and gastric phenotype.
Author:	Hara, Akihito\|Yashima, Kazuo\|Yasugi, Akiko\|Koda, Masaharu\|Kawaguchi, Koichiro\|Harada, Kenichi\|Andachi, Hironobu\|Shiota, Goshi\|Ito, Hisao\|Murawaki, Yoshikazu
PMID:	17671701

34.
Journal:	Carcinogenesis. 2007 Sep;28(9):1851-8. Epub 2007 Aug 11.
Title:	Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns.
Author:	Lea, I A\|Jackson, M A\|Li, X\|Bailey, S\|Peddada, S D\|Dunnick, J K
PMID:	17693665

35.
Journal:	Appl Immunohistochem Mol Morphol. 2007 Dec;15(4):432-40.
Title:	Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings.
Author:	Zheng, Huachuan\|Takahashi, Hiroyuki\|Murai, Yoshihiro\|Cui, Zhengguo\|Nomoto, Kazuhiro\|Tsuneyama, Koichi\|Takano, Yasuo
PMID:	18091387

36.
Journal:	Front Med China. 2007 Feb;1(1):99-103.
Title:	MSI/LOH and extron expression of the FHIT gene in gastric carcinoma.
Author:	Xiao, Yuping\|Mao, Lili\|Han, Chengbo\|Li, Jinyi\|Xu, Lei\|Xin, Yan
PMID:	24557626

37.
Journal:	Virchows Arch. 2008 May;452(5):525-34.
Title:	Mixed-type gastric carcinomas exhibit more aggressive features and indicate the histogenesis of carcinomas.
Author:	Zheng, Hua-chuan\|Li, Xiao-han\|Hara, Takuo\|Masuda, Shinji\|Yang, Xiang-hong\|Guan, Yi-fu\|Takano, Yasuo
PMID:	18266006

38.
Journal:	Rev Med Chil. 2008 Apr;136(4):451-8.
Title:	[Gene methylation patterns in digestive tumors].
Author:	Roa S, Juan Carlos\|Garcia M, Patricia\|Melo A, Angelica\|Tapia E, Oscar\|Villaseca H, Miguel\|Araya O, Juan Carlos\|Guzman G, Pablo
PMID:	18769787

39.
Journal:	Biol Res. 2008;41(3):303-15.
Title:	DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis.
Author:	Bernal, Carolina\|Vargas, Macarena\|Ossandon, Francisco\|Santibanez, Eudocia\|Urrutia, Julio\|Luengo, Victor\|Zavala, Luis F\|Backhouse, Claudia\|Palma, Mariana\|Argandona, Jorge\|Aguayo, Francisco\|Corvalan, Alejandro
PMID:	19399343

40.
Journal:	Oncol Rep. 2009 May;21(5):1251-9.
Title:	Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma.
Author:	Kim, Ji Hun\|Jung, Eun Ji\|Lee, Hye Seung\|Kim, Min A\|Kim, Woo Ho
PMID:	19360301

41.
Journal:	Zhonghua Yi Xue Za Zhi. 2009 Sep 8;89(33):2337-41.
Title:	[Expressions of cyclinB1, FHIT and Ki-67 in 336 gastric carcinoma patients and their clinicopathologic significance].
Author:	Li, Ya-Zhuo\|Zhao, Po
PMID:	20095356

42.
Journal:	Helicobacter. 2009 Oct;14(5):126-34.
Title:	Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients.
Author:	Stec-Michalska, Krystyna\|Peczek, Lukasz\|Michalski, Blazej\|Wisniewska-Jarosinska, Maria\|Krakowiak, Agnieszka\|Nawrot, Barbara
PMID:	19751438

43.
Journal:	J Biol Chem. 2009 Jan 9;284(2):1040-9.
Title:	Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
Author:	Pichiorri, Flavia\|Okumura, Hiroshi\|Nakamura, Tatsuya\|Garrison, Preston N\|Gasparini, Pierluigi\|Suh, Sung-Suk\|Druck, Teresa\|McCorkell, Kelly A\|Barnes, Larry D\|Croce, Carlo M\|Huebner, Kay
PMID:	19004824

44.
Journal:	Hum Pathol. 2009 Mar;40(3):314-22.
Title:	Comparative analysis of protein expressions in primary and metastatic gastric carcinomas.
Author:	Kim, Ji Hun\|Kim, Min A\|Lee, Hye Seung\|Kim, Woo Ho
PMID:	18835621

45.
Journal:	Histol Histopathol. 2010 Apr;25(4):445-52.
Title:	The pathobiological behaviors and prognosis associated with Japanese gastric adenocarcinomas of pure WHO histological subtypes.
Author:	Zheng, Hua-chuan\|Zheng, Yu-shuang\|Xia, Pu\|Xu, Xiao-yan\|Xing, Ya-nan\|Takahashi, Hiroyuki\|Guan, Yi-fu\|Takano, Yasuo
PMID:	20183797

46.
Journal:	Clin Cancer Res. 2010 Jun 15;16(12):3253-9.
Title:	Overexpression of p73 as a tissue marker for high-risk gastritis.
Author:	Carrasco, Gonzalo\|Diaz, Jose\|Valbuena, Jose R\|Ibanez, Paulina\|Rodriguez, Paz\|Araya, Gabriela\|Rodriguez, Carolina\|Torres, Javiera\|Duarte, Ignacio\|Aravena, Edmundo\|Mena, Fernando\|Barrientos, Carlos\|Corvalan, Alejandro H
PMID:	20530692

47.
Journal:	Med Oncol. 2012 Sep;29(3):1529-35.
Title:	Genetic alterations of the WWOX gene in breast cancer.
Author:	Ekizoglu, Seda\|Muslumanoglu, Mahmut\|Dalay, Nejat\|Buyru, Nur
PMID:	21983861

48.
Journal:	Ann Oncol. 2013 Mar;24(3):693-701.
Title:	A clinical-biological risk stratification model for resected gastric cancer: prognostic impact of Her2, Fhit, and APC expression status.
Author:	Bria, E\|De Manzoni, G\|Beghelli, S\|Tomezzoli, A\|Barbi, S\|Di Gregorio, C\|Scardoni, M\|Amato, E\|Frizziero, M\|Sperduti, I\|Corbo, V\|Brunelli, M\|Bersani, S\|Tortora, G\|Scarpa, A
PMID:	23131390

49.
Journal:	Tumour Biol. 2014 Jul;35(7):6815-21.
Title:	Abnormal FHIT protein expression may be correlated with poor prognosis in gastric cancer: a meta-analysis.
Author:	Wang, He-Ling\|Zhou, Ping-Yi\|Liu, Peng\|Zhang, Yu
PMID:	24729090

50.
Journal:	Med Oncol. 2015 Apr;32(4):92.
Title:	Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas.
Author:	He, Dan\|Zhang, Yi-wang\|Zhang, Na-na\|Zhou, Lu\|Chen, Jian-ning\|Jiang, Ye\|Shao, Chun-kui
PMID:	25720522

51.
Journal:	PLoS One. 2015 Apr 14;10(4):e0124576.
Title:	Effect of eradication of Helicobacter pylori on expression levels of FHIT, IL-8 and P73 in gastric mucosa of first-degree relatives of gastric cancer patients.
Author:	Liao, Juan\|Wen, Shichao\|Cao, Lipeng\|Zhou, Yunfeng\|Feng, Zhisong
PMID:	25875960

52.
Journal:	J Dig Dis. 2015 Jul;16(7):385-94.
Title:	The influence of Helicobacter pylori eradication on the expression and methylation status of the FHIT gene in non-cancerous gastric mucosa of dyspeptic patients.
Author:	Peczek, Lukasz\|Zuk, Karolina\|Stec-Michalska, Krystyna\|Medrek, Marta\|Nawrot, Barbara
PMID:	25943773

53.
Journal:	Cancer Res. 2016 Apr 1;76(7):1714-23.
Title:	Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
Author:	Hu, Nan\|Kadota, Mitsutaka\|Liu, Huaitian\|Abnet, Christian C\|Su, Hua\|Wu, Hailong\|Freedman, Neal D\|Yang, Howard H\|Wang, Chaoyu\|Yan, Chunhua\|Wang, Lemin\|Gere, Sheryl\|Hutchinson, Amy\|Song, Guohong\|Wang, Yuan\|Ding, Ti\|Qiao, You-Lin\|Koshiol, Jill\|Dawsey, Sanford
PMID:	26857264

54.
Journal:	Sci Rep. 2016 Mar 10;6:22982.
Title:	Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis.
Author:	Bria, E\|Pilotto, S\|Simbolo, M\|Fassan, M\|de Manzoni, G\|Carbognin, L\|Sperduti, I\|Brunelli, M\|Cataldo, I\|Tomezzoli, A\|Mafficini, A\|Turri, G\|Karachaliou, N\|Rosell, R\|Tortora, G\|Scarpa, A
PMID:	26961069

55.
Journal:	Oncotarget. 2017 Nov 3;8(64):108261-108273.
Title:	FHIT down-regulation was inversely linked to aggressive behaviors and adverse prognosis of gastric cancer: a meta- and bioinformatics analysis.
Author:	Zheng, Hua-Chuan\|Liu, Li-Li
PMID:	29296239