Primary Site >> Stomach Cancer
Gene >> FHIT
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Ref: Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines. PMID: 8640789 |
Ref: Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines. PMID: 9290961 |
Ref: Loss of FHIT expression in gastric carcinoma. PMID: 9788626 |
Ref: Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas. PMID: 9973227 Ref: FHIT gene in gastric cancer: association with tumour progression and prognosis. PMID: 10440747 |
Ref: Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival. PMID: 10618602 Ref: [Abnormal expression of the FHIT gene in human primary gastrointestinal cancers]. PMID: 12205991 |
Ref: Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas. PMID: 11396980 Ref: Fhit protein expression in human gastric cancer and related precancerous lesions. PMID: 11605039 Ref: Characterization of aberrant FHIT transcripts in gastric adenocarcinomas. PMID: 11642547 |
Ref: High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer. PMID: 11916557 Ref: Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer. PMID: 12218081 Ref: Aberrant splicing of FHIT transcripts in human gastric cancer cell lines. PMID: 15080495 |
Ref: Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer. PMID: 12669232 Ref: Tumour suppressor gene expression correlates with gastric cancer prognosis. PMID: 12692839 Ref: Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters. PMID: 12702909 Ref: Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis. PMID: 12810953 Ref: Regression of upper gastric cancer in mice by FHIT gene delivery. PMID: 12958204 Ref: [Sequence analyses of aberrant FHIT transcripts in gastric cancer cell lines]. PMID: 14695704 |
Ref: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. PMID: 15014022 Ref: [Effect of fragile histidine triad gene on apoptosis of MGC-803 gastric cancer cells]. PMID: 15067734 Ref: Loss of WWOX expression in gastric carcinoma. PMID: 15131042 |
Ref: Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection. PMID: 15609389 Ref: About the origin and development of hereditary conventional renal cell carcinoma in a four-generation t(3;8)(p14.1;q24.23) family. PMID: 15756303 Ref: Relationship between abnormality of FHIT gene and EBV infection in gastric cancer. PMID: 15929169 Ref: [Promoter methylation profile in gastric cancer]. PMID: 16163424 Ref: Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients. PMID: 16237777 |
Ref: Loss of Fhit expression is associated with poorer survival in gastric cancer but is not an independent prognostic marker. PMID: 16217683 Ref: Loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma. PMID: 16773697 |
Ref: Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: an immunostaining study on the tissue microarray. PMID: 16714395 Ref: [Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes]. PMID: 17369979 Ref: Promoter hypermethylation of CDH1, FHIT, MTAP and PLAGL1 in gastric adenocarcinoma in individuals from Northern Brazil. PMID: 17552003 Ref: Expression of Fhit, Mlh1, p16INK4A and E-cadherin in early gastric neoplasia: Correlation with histological grade and gastric phenotype. PMID: 17671701 Ref: Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns. PMID: 17693665 Ref: Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings. PMID: 18091387 Ref: MSI/LOH and extron expression of the FHIT gene in gastric carcinoma. PMID: 24557626 |
Ref: Mixed-type gastric carcinomas exhibit more aggressive features and indicate the histogenesis of carcinomas. PMID: 18266006 Ref: [Gene methylation patterns in digestive tumors]. PMID: 18769787 Ref: DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis. PMID: 19399343 |
Ref: Comparative analysis of protein expressions in primary and metastatic gastric carcinomas. PMID: 18835621 Ref: Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions. PMID: 19004824 Ref: Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma. PMID: 19360301 Ref: Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients. PMID: 19751438 Ref: [Expressions of cyclinB1, FHIT and Ki-67 in 336 gastric carcinoma patients and their clinicopathologic significance]. PMID: 20095356 |
Ref: The pathobiological behaviors and prognosis associated with Japanese gastric adenocarcinomas of pure WHO histological subtypes. PMID: 20183797 Ref: Overexpression of p73 as a tissue marker for high-risk gastritis. PMID: 20530692 |
Ref: Genetic alterations of the WWOX gene in breast cancer. PMID: 21983861 |
Ref: A clinical-biological risk stratification model for resected gastric cancer: prognostic impact of Her2, Fhit, and APC expression status. PMID: 23131390 |
Ref: Abnormal FHIT protein expression may be correlated with poor prognosis in gastric cancer: a meta-analysis. PMID: 24729090 |
Ref: Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas. PMID: 25720522 Ref: Effect of eradication of Helicobacter pylori on expression levels of FHIT, IL-8 and P73 in gastric mucosa of first-degree relatives of gastric cancer patients. PMID: 25875960 Ref: The influence of Helicobacter pylori eradication on the expression and methylation status of the FHIT gene in non-cancerous gastric mucosa of dyspeptic patients. PMID: 25943773 |
Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer. PMID: 26857264 Ref: Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis. PMID: 26961069 |
Ref: FHIT down-regulation was inversely linked to aggressive behaviors and adverse prognosis of gastric cancer: a meta- and bioinformatics analysis. PMID: 29296239 |