Primary Site >> Esophagus Cancer

Gene >> FHIT

Journal: Oncogene. 1997 Oct 2;15(14):1653-9.
Title: Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas.
Author: Michael, D|Beer, D G|Wilke, C W|Miller, D E|Glover, T W
PMID: 9349498
Journal: Oncogene. 1997 Jul 3;15(1):101-5.
Title: FHIT gene alterations in esophageal cancer and ulcerative colitis (UC).
Author: Zou, T T|Lei, J|Shi, Y Q|Yin, J|Wang, S|Souza, R F|Kong, D|Shimada, Y|Smolinski, K N|Greenwald, B D|Abraham, J M|Harpaz, N|Meltzer, S J
PMID: 9233782
Journal: Cancer Res. 1998 Aug 1;58(15):3429-34.
Title: Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas.
Author: Tanaka, H|Shimada, Y|Harada, H|Shinoda, M|Hatooka, S|Imamura, M|Ishizaki, K
PMID: 9699676
Journal: Zhonghua Zhong Liu Za Zhi. 1998 Jul;20(4):258-60.
Title: [Association of fragile histidine triad gene (FHIT) with susceptibility to esophageal cancer. A preliminary study].
Author: Li, W|Wang, X|Cheng, G
PMID: 10920977
Journal: Cancer Res. 2000 Mar 1;60(5):1177-82.
Title: Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus.
Author: Mori, M|Mimori, K|Shiraishi, T|Alder, H|Inoue, H|Tanaka, Y|Sugimachi, K|Huebner, K|Croce, C M
PMID: 10728669
Journal: Cancer Genet Cytogenet. 2000 May;119(1):56-61.
Title: Anomalous transcripts and allelic deletions of the FHIT gene in human esophageal cancer.
Author: Menin, C|Santacatterina, M|Zambon, A|Montagna, M|Parenti, A|Ruol, A|D'Andrea, E
PMID: 10812172
Journal: Cancer. 2000 Jul 1;89(1):5-11.
Title: Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history.
Author: Shimada, Y|Sato, F|Watanabe, G|Yamasaki, S|Kato, M|Maeda, M|Imamura, M
PMID: 10896994
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Dec;22(6):548-50.
Title: [Surgical treatment of malignant esophageal tumors in PUMC Hospital].
Author: Guo, H|Li, Z|Zhang, Z|Sun, C|Xu, L|Li, W|Wang, S|Wu, M
PMID: 12903401
Journal: Cancer Res. 2001 Feb 15;61(4):1578-84.
Title: Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
Author: Ishii, H|Dumon, K R|Vecchione, A|Trapasso, F|Mimori, K|Alder, H|Mori, M|Sozzi, G|Baffa, R|Huebner, K|Croce, C M
PMID: 11245468
Journal: Oncology. 2001;61(3):205-11.
Title: Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
Author: Kitamura, A|Yashima, K|Okamoto, E|Andachi, H|Hosoda, A|Kishimoto, Y|Shiota, G|Ito, H|Kaibara, N|Kawasaki, H
PMID: 11574776
Journal: Surgery. 2002 Jan;131(1 Suppl):S1-6.
Title: Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract.
Author: Morita, Masaru|Saeki, Hiroshi|Mori, Masaki|Kuwano, Hiroyuki|Sugimachi, Keizo
PMID: 11821780
Journal: Int J Mol Med. 2003 Apr;11(4):441-7.
Title: FHIT expression and hypermethylation in esophageal squamous cell carcinoma.
Author: Noguchi, Tsuyoshi|Takeno, Shinsuke|Kimura, Yasuhiko|Uchida, Yuzo|Daa, Tsutomu|Yokoyama, Shigeo|Gabbert, Helmut E|Mueller, Wolfram
PMID: 12632095
Journal: Oncology. 2003;64(3):275-9.
Title: Microsatellite instability is often observed in esophageal carcinoma patients with allelic loss in the FHIT/FRA3B locus.
Author: Mimori, Koshi|Inoue, Hiroshi|Shiraishi, Takeshi|Matsuyama, Ayumi|Mafune, Ken-ichi|Tanaka, Yoichi|Mori, Masaki
PMID: 12697969
Journal: Ai Zheng. 2003 May;22(5):492-5.
Title: [HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County].
Author: Liu, Yan-Li|Li, Xue-Min|Jin, Guo-Liang|Yan, Xia|Yang, Jian-Zhu|Wang, Jun-Ling|Li, Yue-Hong|Wang, Feng-Rong|Zhang, Xiang-Hong
PMID: 12753709
Journal: Ai Zheng. 2004 Sep;23(9):992-8.
Title: [Allelic loss and down-regulation of FHIT gene expression in esophageal squamous cell carcinoma].
Author: Liu, Fu-Xing|Huang, Xiao-Ping|Zhao, Chun-Xia|Xu, Xin|Han, Ya-Ling|Cai, Yan|Wu, Ren-Liang|Wu, Min|Zhan, Qi-Min|Wang, Ming-Rong
PMID: 15363189
Journal: Cancer Res. 2006 Dec 1;66(23):11287-92.
Title: Fhit modulates the DNA damage checkpoint response.
Author: Ishii, Hideshi|Mimori, Koshi|Inoue, Hiroshi|Inageta, Taeko|Ishikawa, Kazuhiro|Semba, Shuho|Druck, Teresa|Trapasso, Francesco|Tani, Kenzaburo|Vecchione, Andrea|Croce, Carlo M|Mori, Masaki|Huebner, Kay
PMID: 17145874
Journal: Anticancer Res. 2006 May-Jun;26(3B):2243-8.
Title: Expression of FHIT in esophageal epithelium and carcinoma: reference to drinking, smoking and multicentric carcinogenesis.
Author: Morita, Masaru|Oyama, Tsunehiro|Nakata, Shoji|Ono, Kenji|Sugaya, Masakazu|Uramoto, Hidetaka|Yoshimatsu, Takashi|Hanagiri, Takeshi|Sugio, Kenji|Yasumoto, Kosei
PMID: 16821595
Journal: Eur J Cancer. 2006 May;42(7):972-80. Epub 2006 Mar 27.
Title: Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma.
Author: Lee, Eun Ju|Lee, Bo Bin|Kim, Jin Wook|Shim, Young Mog|Hoseok, I|Han, Joungho|Cho, Eun Yoon|Park, Joobae|Kim, Duk-Hwan
PMID: 16564166
Journal: Int J Cancer. 2006 Sep 1;119(5):1023-7.
Title: Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells.
Author: Soma, Toshiya|Kaganoi, Junichi|Kawabe, Atsushi|Kondo, Kan|Imamura, Masayuki|Shimada, Yutaka
PMID: 16570269
Journal: Cancer Res. 2008 Jun 1;68(11):4163-72.
Title: Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays.
Author: Nancarrow, Derek J|Handoko, Herlina Y|Smithers, B Mark|Gotley, David C|Drew, Paul A|Watson, David I|Clouston, Andrew D|Hayward, Nicholas K|Whiteman, David C
PMID: 18519675
Journal: J Gastroenterol Hepatol. 2008 Dec;23 Suppl 2:S205-9.
Title: Identification of the expression profile of apoptotic esophageal cancer cells by adenoviral-fragile histidine triad treatment.
Author: Mimori, Koshi|Ishii, Hideshi|Inoue, Hiroshi|Barnard, Graham F|Mori, Masaki
PMID: 19120899
Journal: Dis Esophagus. 2009;22(2):143-50.
Title: Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus.
Author: Kim, Y T|Park, J-Y|Jeon, Y K|Park, S J|Song, J Y|Kang, C H|Sung, S W|Kim, J H
PMID: 18847451
Journal: Anticancer Res. 2009 Apr;29(4):1243-7.
Title: Gene mutations in esophageal mucosa of chagas disease patients.
Author: DA Silva Manoel-Caetano, Fernanda|Silveira, Aparecida F P|Silva, Ana Elizabete
PMID: 19414370
Journal: J Cell Biochem. 2009 Aug 15;107(6):1097-106.
Title: Nit1 and Fhit tumor suppressor activities are additive.
Author: Sun, Jin|Okumura, Hiroshi|Yearsley, Martha|Frankel, Wendy|Fong, Louise Y|Druck, Teresa|Huebner, Kay
PMID: 19479888
Journal: Tsitol Genet. 2009 Nov-Dec;43(6):40-4.
Title: [Genetic and epigenetic changes of FHIT gene in patients with esophageal cancer].
Author: Tsao, Iui|Atramentova, L A
PMID: 20458975
Journal: BMC Gastroenterol. 2010 Feb 17;10:20.
Title: Chromosomal imbalances are uncommon in chagasic megaesophagus.
Author: Bellini, Marilanda F|Manzato, Antonio J|Silva, Ana E|Varella-Garcia, Marileila
PMID: 20163722
Journal: Anticancer Res. 2011 May;31(5):1685-90.
Title: Gene mutations and polymorphisms of TP53 and FHIT in chronic esophagitis and esophageal carcinoma.
Author: Silveira, Aparecida Perpetuo Fedossi|Da Silva Manoel-Caetano, Fernanda|Aoki, Sergio|Yamasaki, Lilian Hiromi Tomonari|Rahal, Paula|Silva, Ana Elizabete
PMID: 21617227
Journal: World J Gastroenterol. 2011 Jun 28;17(24):2909-23.
Title: Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes.
Author: Brown, Jacqueline|Bothma, Hannelie|Veale, Robin|Willem, Pascale
PMID: 21734802
Journal: Dis Esophagus. 2012 Jan;25(1):81-7.
Title: Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.
Author: Chava, S|Mohan, V|Shetty, P J|Manolla, M L|Vaidya, S|Khan, I A|Waseem, G L|Boddala, P|Ahuja, Y R|Hasan, Q
PMID: 21668571
Journal: J Gastroenterol Hepatol. 2012 Nov;27(11):1752-8.
Title: Fhit, E-cadherin, p53, and activation-induced cytidine deaminase expression in endoscopically resected early stage esophageal squamous neoplasia.
Author: Hayashi, Akihiro|Yashima, Kazuo|Takeda, Yohei|Sasaki, Shuji|Kawaguchi, Koichiro|Harada, Kenichi|Murawaki, Yoshikazu|Ito, Hisao
PMID: 22742976
Journal: Oncol Lett. 2015 Jan;9(1):430-436. Epub 2014 Nov 7.
Title: Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer.
Author: Chang, Zhiwei|Zhang, Weijie|Chang, Zhijun|Song, Min|Qin, Yanru|Chang, Fubao|Guo, Haiyun|Wei, Qingli
PMID: 25436004
Journal: Cancer Res. 2016 Apr 1;76(7):1714-23.
Title: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
Author: Hu, Nan|Kadota, Mitsutaka|Liu, Huaitian|Abnet, Christian C|Su, Hua|Wu, Hailong|Freedman, Neal D|Yang, Howard H|Wang, Chaoyu|Yan, Chunhua|Wang, Lemin|Gere, Sheryl|Hutchinson, Amy|Song, Guohong|Wang, Yuan|Ding, Ti|Qiao, You-Lin|Koshiol, Jill|Dawsey, Sanford
PMID: 26857264
Journal: Clin Epigenetics. 2016 Apr 22;8:43.
Title: The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma.
Author: Ma, Kai|Cao, Baoping|Guo, Mingzhou
PMID: 27110300
Journal: Oncol Lett. 2017 Jul;14(1):587-592.
Title: Frequent aberrant p53 and Fhit expression in endoscopically resected superficial hypopharyngeal cancer and esophageal cancer.
Author: Yamamoto, Sohei|Yashima, Kazuo|Kawata, Soichiro|Hosoda, Kohei|Tamoto, Akihiro|Ikebuchi, Yuichiro|Matsumoto, Kazuya|Kawaguchi, Koichiro|Harada, Kenichi|Murawaki, Yoshikazu|Isomoto, Hajime
PMID: 28693209
Journal: Oncol Lett. 2017 Jul;14(1):737-742.
Title: Expression of methylation-modulated tumor-related genes in endoscopically resected early esophageal squamous neoplasia.
Author: Hosoda, Kohei|Yashima, Kazuo|Tamoto, Akihiro|Yamamoto, Sohei|Kawata, Soichiro|Ikebuchi, Yuichiro|Matsumoto, Kazuya|Kawaguchi, Koichiro|Harada, Kenichi|Murawaki, Yoshikazu|Isomoto, Hajime
PMID: 28693228
Journal: J Cancer. 2018 Jul 30;9(16):2865-2875.
Title: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
Author: Dong, Yin|Yi, Xu|Yujie, Zhen|Huixia, Zhang|Yan, Chen
PMID: 30123355