Primary Site >> Esophagus Cancer

Gene >> FHIT

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Ref: FHIT gene alterations in esophageal cancer and ulcerative colitis (UC).
PMID: 9233782
Ref: Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas.
PMID: 9349498
 Ref: Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas.
PMID: 9699676
Ref: [Association of fragile histidine triad gene (FHIT) with susceptibility to esophageal cancer. A preliminary study].
PMID: 10920977
 Ref: Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus.
PMID: 10728669
Ref: Anomalous transcripts and allelic deletions of the FHIT gene in human esophageal cancer.
PMID: 10812172
Ref: Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history.
PMID: 10896994
Ref: [Surgical treatment of malignant esophageal tumors in PUMC Hospital].
PMID: 12903401
 Ref: Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
PMID: 11245468
Ref: Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
PMID: 11574776
 Ref: Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract.
PMID: 11821780
 Ref: FHIT expression and hypermethylation in esophageal squamous cell carcinoma.
PMID: 12632095
Ref: Microsatellite instability is often observed in esophageal carcinoma patients with allelic loss in the FHIT/FRA3B locus.
PMID: 12697969
Ref: [HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County].
PMID: 12753709
 Ref: [Allelic loss and down-regulation of FHIT gene expression in esophageal squamous cell carcinoma].
PMID: 15363189
 Ref: Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma.
PMID: 16564166
Ref: Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells.
PMID: 16570269
Ref: Expression of FHIT in esophageal epithelium and carcinoma: reference to drinking, smoking and multicentric carcinogenesis.
PMID: 16821595
Ref: Fhit modulates the DNA damage checkpoint response.
PMID: 17145874
 Ref: Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays.
PMID: 18519675
Ref: Identification of the expression profile of apoptotic esophageal cancer cells by adenoviral-fragile histidine triad treatment.
PMID: 19120899
 Ref: Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus.
PMID: 18847451
Ref: Gene mutations in esophageal mucosa of chagas disease patients.
PMID: 19414370
Ref: Nit1 and Fhit tumor suppressor activities are additive.
PMID: 19479888
Ref: [Genetic and epigenetic changes of FHIT gene in patients with esophageal cancer].
PMID: 20458975
 Ref: Chromosomal imbalances are uncommon in chagasic megaesophagus.
PMID: 20163722
 Ref: Gene mutations and polymorphisms of TP53 and FHIT in chronic esophagitis and esophageal carcinoma.
PMID: 21617227
Ref: Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes.
PMID: 21734802
 Ref: Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.
PMID: 21668571
Ref: Fhit, E-cadherin, p53, and activation-induced cytidine deaminase expression in endoscopically resected early stage esophageal squamous neoplasia.
PMID: 22742976
 Ref: Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer.
PMID: 25436004
 Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
PMID: 26857264
Ref: The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma.
PMID: 27110300
 Ref: Frequent aberrant p53 and Fhit expression in endoscopically resected superficial hypopharyngeal cancer and esophageal cancer.
PMID: 28693209
Ref: Expression of methylation-modulated tumor-related genes in endoscopically resected early esophageal squamous neoplasia.
PMID: 28693228
 Ref: Relationship between the Methylation of Folic Acid Metabolism-Related Genes and the Incidence and Prognosis of Esophageal Cancer among Ethnic Kazakhs.
PMID: 30123355